Patents Assigned to Massachusetts Institute for Technology
  • Publication number: 20120202742
    Abstract: The invention relates to an drug delivery device and a method for delivering multiple drugs over a prolonged period of time. The drug delivery device has two or more unitary segments comprising a drug-permeable polymeric substance, wherein at least one of the segments further comprises a pharmaceutically active agent. The invention also relates to a method for the treatment of a benign ovarian secretory disorder in a female mammal, a method of contraception, and a method of relieving the symptoms associated with menopausal, perimenopausal and post-menopausal periods in a woman.
    Type: Application
    Filed: January 14, 2011
    Publication date: August 9, 2012
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation D/B/A Massachusetts General Hospital
    Inventors: Eyal S. Ron, Robert S. Langer, William F. Crowley, JR.
  • Patent number: 8238467
    Abstract: An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: August 7, 2012
    Assignee: Massachusetts Institute of Technology
    Inventor: William J. Dally
  • Patent number: 8235071
    Abstract: A method for implementing a logic operation employs an all fluid-based no-moving part micro-mechanical logic family of microfluidic bubble logic devices that are constructed from complex sequences of microfluidic channels, microfluidic bubble modulators for programming the devices, and microfluidic droplet/bubble memory elements for chemical storage and retrieval. The input is a sequence of bubbles/droplets encoding information, with the output being another sequence of bubbles/droplets. For performing a set of reactions/tasks, the modulators program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the microfluidic channel sequence, utilizing the generated bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: August 7, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Manu Prakash, Neil Gershenfeld
  • Patent number: 8234998
    Abstract: The present invention comprises an automated apparatus capable of spray depositing polyelectrolytes via the LbL mechanism with minimal or no human interaction. In certain embodiments, the apparatus sprays atomized polyelectrolytes onto a vertically oriented substrate. To counteract the effects of irregular spray patterns, the substrate is preferably slowly rotated about a central axis. In certain embodiments, the apparatus also includes a forced pathway for the droplets, such as a pathway created by using a vacuum. In this way, a thicker or three-dimensional substrate can be coated. In certain embodiments, the apparatus is designed so as to be scalable. Thus, through the use of multiple instantiations of the apparatus, a large or irregularly shaped substrate can be coated. Rolls of textile can therefore be coated using the apparatus. Additionally, the present invention includes a method to uniformly coat a substrate, such as a hydrophobic textile material, using aqueous solutions of polyelectrolytes.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: August 7, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Kevin C. Krogman, Paula T. Hammond, Nicole S. Zacharia
  • Patent number: 8238470
    Abstract: An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: August 7, 2012
    Assignee: Massachusetts Institute of Technology
    Inventor: William J. Dally
  • Publication number: 20120192997
    Abstract: Methods to enhance the quality of grain boundary networks are described. The process can result in the production of a metal including a relatively large fraction of special grain boundaries (e.g., a fraction of special grain boundaries of at least about 55%).
    Type: Application
    Filed: February 1, 2011
    Publication date: August 2, 2012
    Applicants: Mitsubishi Materials Corporation, Massachusetts Institute of Technology
    Inventors: Kenichi Yaguchi, Christopher A. Schuh
  • Publication number: 20120194508
    Abstract: Autostereoscopic display. The display includes an array of elements from which light emanates, the elements being rotatable about two orthogonal axes by microcontrollers. An eye tracker is provided for determining the location in three dimensions of at least one eye viewing the array. The microcontrollers, using information from the eye tracker, rotate the elements to mimic a concave surface to deliver light to the eye. It is preferred that the elements are mirrors and the display further includes a projector for projecting an image on the array for reflection to the eye. The elements themselves may include means for generating light rather than reflecting light.
    Type: Application
    Filed: July 27, 2011
    Publication date: August 2, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Robert Matthew Panas, Jonathan B. Hopkins
  • Publication number: 20120196100
    Abstract: Co-continuous structured composite. The composite material includes a continuous material phase in intimate contact with a continuous second phase. A preferred embodiment has a continuous glassy polymer and a continuous elastomeric polymer; or a shape memory polymer phased together with an elastomeric phase. The composite of the invention has a combination of improved mechanical properties such as a unique combination of stiffness, strength and energy absorption, damage tolerance, multiple time constant viscoelastic and viscoplastic behaviors, and shape memory characteristics.
    Type: Application
    Filed: July 26, 2011
    Publication date: August 2, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Mary C. Boyce, Lifeng Wang, Jacky Lau
  • Publication number: 20120193606
    Abstract: Semiconductor nanocrystals including III-V semiconductors can include a core including III-V alloy. The nanocrystal can include an overcoating including a II-VI semiconductor.
    Type: Application
    Filed: March 12, 2012
    Publication date: August 2, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Moungi G. Bawendi, Sang-wook Kim, John P. Zimmer
  • Publication number: 20120194638
    Abstract: A holographic video display employs at least one light source adapted to produce at least one wavelength of monochromatic light, a video signal generator, at least one guided-wave acousto-optic modulator for diffracting light received from the light source according to signals received from the video signal generator, a vertical scanning subsystem, and an optical path between the acousto-optic modulator and the vertical scanning subsystem. The optical path may preferably include a Bravais lens system, at least one Fourier transform lens system, and at least one moving horizontal mirror.
    Type: Application
    Filed: April 2, 2012
    Publication date: August 2, 2012
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Daniel E. SMALLEY, Quinn Y. J. SMITHWICK, V. Michael BOVE, JR.
  • Patent number: 8232182
    Abstract: A transfer layer includes a transparent substrate. A buffer layer is formed on the transparent substrate that comprises PbO, GaN, PbTiO3, La0.5Sr0.5CoO3 (LSCO), or LaxPb1-xCoO3 (LPCO) so that separation between the buffer layer and the transparent substrate occurs at substantially high temperatures.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: July 31, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Il-Doo Kim, Harry L. Tuller, Yong Woo Choi, Akintunde I. Akinwande
  • Patent number: 8232136
    Abstract: The disclosure relates to a method and apparatus for micro-patterning organic layers of OLEDs. The disclosed methods do not require applying pressure to the film, nor do they require heat treatment, surface treatment or fast release rate of a stamp from the substrate. The disclosed methods are particularly advantageous over the conventional shadow masking techniques for providing large array fabrication with small features. In one embodiment of the disclosure, one or more organic films are selected for the OLED as a function of their individual or combined sublimation temperature. The material is selected in view of the depth and shape of the features that are to be formed in the organic layer. The disclosed embodiments can provide minimum feature size of 13 ?m which is suitable for high resolution OLED displays.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: July 31, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Vladimir Bulovic, Jennifer J. Yu
  • Patent number: 8232722
    Abstract: A light emitting device includes a semiconductor nanocrystal and a charge transporting layer that includes an inorganic material. The charge transporting layer can be a hole or electron transporting layer. The inorganic material can be an inorganic semiconductor.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: July 31, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Moungi G. Bawendi, Vladimir Bulovic, Seth Coe-Sullivan, Jean-Michel Caruge, Jonathan Steckel, Alexi Arango, Jonathan E. Halpert
  • Patent number: 8233717
    Abstract: A system and method for extracting feature data of dynamic objects selects sequential N frames of a video file up front, where N is a positive integer, and divides each of the N frames into N*N squares. The system and method further selects any n frames from the N frames, selects any n rows and n columns of the n frames to obtain n*n*n squares, where n is a positive integer. The system and method further extracts feature data from the video file by computing averages and differences for pixel values of the n*n*n squares.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: July 31, 2012
    Assignees: Hon Hai Industry Co., Ltd., Massachusetts Institute of Technology
    Inventor: Cheng-Hsien Lee
  • Publication number: 20120186352
    Abstract: A kit for detecting the presence of an explosive includes a pulsed focused energy source located at a target distance away from a substrate, the energy having a magnitude sufficient to release the internal energy of an explosive if present on the substrate and thereby generate an acoustic wave. The kit also includes a detector adapted to detect the acoustic wave at a detection distance away from the substrate.
    Type: Application
    Filed: January 20, 2011
    Publication date: July 26, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Charles M. Wynn, Robert W. Haupt, Sumanth Kaushik, Stephen T. Palmacci
  • Publication number: 20120186456
    Abstract: The system includes a vertically-oriented cylinder sized to receive a selected amount of water and a substance such as coffee to be brewed. A plunger is slidingly received within the cylinder. A filter assembly separates the grounds from the brewed drink. A heating element is wrapped around the cylinder to maintain a selected temperature within the cylinder.
    Type: Application
    Filed: December 22, 2011
    Publication date: July 26, 2012
    Applicant: Massachusetts Institute of Technology
    Inventor: Jeremy J. Kuempel
  • Publication number: 20120188474
    Abstract: The imager includes a lens for focusing infrared light forming a thermal image onto a liquid crystal array thereby changing the temperature of the liquid crystals to alter a physical property of the liquid crystals. A source of visible polarized light is arranged to illuminate the liquid crystal array so that the polarization of light reflected from the liquid crystal array varies with changes in temperature of the liquid crystals. A cross polarizer receives and transmits therethrough the light reflected from the liquid crystal array, the cross polarizer adapted to change the intensity of the light. An imager receives and detects the change in intensity of the light from the cross polarizer so that the thermal image is recreated as an electronic signal. In a preferred embodiment, the physical property is index of refraction and the liquid crystal array includes birefringent nematic liquid crystals.
    Type: Application
    Filed: July 28, 2011
    Publication date: July 26, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Robert K. Reich, Harry R. Clark
  • Patent number: 8228148
    Abstract: A persistent-mode magnet, assembled from superconducting annuli, provides a micro coil NMR, in which compactness and manufacturability are provided for a variety of applications. An annular magnet for micro NMR can include a YBCO-annulus Helmholtz coil, for example, that can energized by a magnet system and then transported for use at a second location with an operating system.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: July 24, 2012
    Assignees: Massachusetts Institute Of Technology, Railway Technical Research Institute
    Inventors: Yukikazu Iwasa, Masaru Tomita
  • Patent number: 8229130
    Abstract: A conversation shielding system comprises sensors that detect the location of a confidential conversation and the presence and location of a potential eavesdropper, audio output devices that produce masking sounds to shield the conversation from the eavesdropper, and a controller that automatically controls the operation of the output devices in response to data from the sensors. An optional portable controller may manually engage the system. A method for shielding conversation comprises identifying a conversation to be shielded, detecting a potential eavesdropper, automatically determining masking sound types, locations and volume that will shield the conversation, directing emission of masking sounds from at least one audio output device in order to shield the conversation, including adjusting the masking sound type, location, and volume in response to movement of the conversation or the eavesdropper, and continuing to shield the conversation until it ends or the eavesdropper is no longer detected.
    Type: Grant
    Filed: September 10, 2008
    Date of Patent: July 24, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Joseph A. Paradiso, Yasuhiro Ono
  • Patent number: 8227035
    Abstract: A self-replicating monolayer system employing polymerization of monomers or nanoparticle ensembles on a defined template provides a method for synthesis of two-dimensional single molecule polymers. Systems of self-replicating monolayers are used as templates for growth of inorganic colloids. A preferred embodiment employs SAM-based replication, wherein an initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition. The second monolayer is polymerized in place and the monolayers are separated to form a replicate. Both may then function as templates for monolayer assemblies. A generic self-replicating monomer unit comprises a polymerizable moiety attached by methylene repeats to a recognition element and an ending unit that will not interfere with the chosen recognition chemistry. The recognition element is self-complementary, unless a set of two replicating monomers with compatible cross-linking chemistry is employed.
    Type: Grant
    Filed: July 19, 2009
    Date of Patent: July 24, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Joseph M. Jacobson, David W. Mosley