Abstract: A method of transmitting optical pulses in a transmission media includes separating a coherent source optical pulse into a plurality of mutually coherent pulses, and producing a series of mutually coherent optical pulses from the plurality of pulses. The series is transmitted through the media, and the pulses of the series are received at a distant region of the media. The series of pulses is adapted to interfere and form a packet whose width is narrower than the width of any pulse of the series at the distant region.

Abstract: A collision recovery method for use in a Wireless Location System includes receiving a transmission from a wireless transmitter at multiple signal collection systems and multiple antenna ports of each of the multiple signal collection systems. At each of the multiple signal collection systems, the transmission received at each antenna port is converted into a digital format, and digital data representative of the received transmission is stored. The transmission is then demodulated, and TDOA analysis is performed on the digital data from pairs of signal collection systems. The location of the wireless transmitter is determined using the TDOA data. The method further involves verifying that the RF data from each antenna port is from the wireless transmitter to be located, e.g., by demodulating a segment of the transmission received at each antenna port and verifying that at least a combination of the following fields is correct: MIN, MSID, TMSI, IMSI, and ESN.

Abstract: A fiber optic needle probe for measuring or imaging the internal structure of a specimen includes a needle defining a bore, an optical fiber substantially positioned within the bore, and a beam director in optical communication with the optical fiber. At least a portion of the wall of the needle is capable of transmitting light. The beam director directs light from the optical fiber to an internal structure being imaged and receives light from the structure through a transparent portion of the wall. An actuating device causes motion of any, or all of, the needle, optical fiber, and beam director to scan the internal structure of the specimen. The fiber optic needle probe allows imaging inside a solid tissue or organ without intraluminal insertion. When used in conjunction with an OCT imaging system, the fiber optic needle probe enables tomographic imaging of the microstructure of internal organs and tissues which were previously impossible to image in a living subject.

Abstract: An optical bit rate for communication systems. The optical bit rate converter converts an ultra-high speed optical data stream to a lower rate optical data stream. In one embodiment, the optical bit rate converter converts the ultra-high speed optical data stream to a lower rate optical data stream that can be detected and processed electronically. The optical rate converter includes a buffer presenting a repeating optical data bit pattern, an optical sampler presenting an optical sampling bit stream, and an optical correlator. The optical correlator has a first input in communication with the output of the buffer and a second input in communication with the output of the optical sampler. The optical correlator produces a rate-converted optical data bit stream at its output in response to the repeating optical data bit pattern produced by the buffer and the optical sampling bit stream produced by the optical sampler.

Abstract: Methods are provided for the fabrication of hydrophilic coatings on hydrophobic surfaces. In one embodiment, a polyethylene oxide (PEO) coating is fabricated on the surface of a polymeric material by contacting the surface with a methacrylic acid or acrylic acid monomer. The monomer first is reacted, for example by irradiation with an electron beam, to polymerize and covalently attach the monomer to the surface, to improve the hydrophilicity of the polymeric material. A coating of PEO molecules is subsequently attached to the polymer surface by hydrogen bond complexation. The PEO coating then may be covalently grafted onto the surface, for example, by irradiation grafting with an electron beam. The covalent grafting of a coating of the methacrylic or acrylic monomers to the surface greatly improves the wettability of the surface, and facilitates the covalent or non-covalent attachment of a coating of PEO to the polymer surface.

Abstract: An apparatus for optimal control of distributed actuator and sensor arrays includes a control system having a state estimator including an operator which acts on estimation error through convolution with respect to a spatial variable to generate a state estimate, and a control output generator which applies a control operator to the state estimate through convolution with respect to the spatial variable. A method of designing an optimized control system includes the steps of obtaining a system model, computing a transform of the model with respect to the spatial domain, solving linear matrix inequalities to generate auxiliary variables, performing an inverse transform on the auxiliary variables, and computing an estimator operator and a control operator for a model-based estimator control system.

Abstract: The present invention provides a system for the growth of C. tetani and production of Tetanus Toxin for use in formulating Tetanus Toxoid preparations. The system includes growth media that contain significantly reduced levels of meat or dairy by-products using non-animal based products to replace the animal-derived products. Preferred media are substantially free of animal-derived products.

Abstract: Binary optics are used in an illumination system for a color projection display. In one embodiment a broad spectrum light source illuminates a multilevel optical phase element which disperses the broad spectrum light from the light source by diffraction. A display having a number of pixel elements, each capable of transmitting a predetermined spectral region, is positioned within the near field region of the multilevel optical phase element so as to receive the light dispersed by the multilevel phase element.

Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.

Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an impedance sensor. The impedance sensor has an electrode positioned to measure the impedance of a portion of the target area between the needle and the electrode to indicate the depth of penetration of the needle into the target area.

Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.

Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an electrolytic actuator which pumps the formulation through the bore.

Abstract: An injector includes a housing having a chamber for holding a liquid formulation of an active principle to be injected into a biological body and an output port in fluid communication with the chamber through which the liquid formulation is injected. A piston is positioned within the housing, and includes an end portion with substantially the same shape as the chamber. A magnetic force draws the piston and housing together to expel the liquid formulation out of the chamber through the output port.

Abstract: Micron scale dielectric items are manipulated by methods and apparatus taking advantage of spatially non-uniform field. Such fields give rise to a force on dielectric items, directing them generally toward regions of more concentrated field. The electrode may be elongated, either unitary, with a generally planar counter electrode, or dual, such as parallel pins, loops or plates. If dual, particles are generally attracted to regions of high field concentration, including tips, edges and spaces between electrode conductors. Items can be granular, threadlike, or sheets, and microelectronic parts and other shapes. Items can also be collected directly into a recess of a pharmaceutical material delivery microchip, with a conductive membrane of the microchip acting as a manipulating electrode. Items are attracted without regard to their surface charge, or the polarity of the field, which can be AC or DC. Charging, or knowing the charge of items to be manipulated is not necessary.

Abstract: A collaborative online tele-operation system allows an audience of many participants to simultaneously share control of a single remote actor, such that the actions of the actor are based on the ongoing collective preferences of the audience.

Abstract: A method and apparatus for telemetering data on a channel having a maximum data rate by utilizing a power efficient communication protocol is provided. The data to be telemetered comprises a number of source symbols where each source symbol is characterized by a probability of occurrence. A sequence of signals forming codewords having an energy and a length is produced. The length for the codewords is based at least on the number of symbols to be coded. Each codeword signifies a specified source symbol on the basis of a mapping between source symbols and codewords. The mapping is such that each source symbol of lower probability of occurrence is associated with a codeword of at least equal energy.

Abstract: The present invention is a network architecture or framework that supports hosting and content distribution on a truly global scale. The inventive framework allows a Content Provider to replicate and serve its most popular content at an unlimited number of points throughout the world. The inventive framework comprises a set of servers operating in a distributed manner. The actual content to be served is preferably supported on a set of hosting servers (sometimes referred to as ghost servers). This content comprises HTML page objects that, conventionally, are served from a Content Provider site. In accordance with the invention, however, a base HTML document portion of a Web page is served from the Content Provider's site while one or more embedded objects for the page are served from the hosting servers, preferably, those hosting servers near the client machine. By serving the base HTML document from the Content Provider's site, the Content Provider maintains control over the content.

Abstract: The invention relates to a method and apparatus for requesting data from one of a plurality of servers. A virtual network of nodes is generated in response to a data request. A first node on the virtual network of nodes is chosen randomly, and a path generated from the first node to the root on the virtual network. At least one node on the path is mapped to a respective one of the plurality of servers and data is requested from a server. The node may be mapped to the server using the method and apparatus for distributing a request to one of a plurality of resources of the present invention.

Abstract: An image processing system for generating a class model from an image by identifying relative relationships between different properties of different image regions, includes a region partitioner a relationship processor, a template generator and an image detector. The image processing system utilizes a class model defined by one or more relative relationships between a plurality of image patches. The relative relationships describe the overall organization of images within an image class. The relative relationships are encoded in a global deformable template which can be used to classify or detect images. The class model may be pre-defined or generated by the image processing system. In one embodiment, the class model is generated from a low resolution image.

Abstract: A synthetic aperture system for producing a non-periodic pattern in a region of overlap. The system includes a source of electromagnetic radiation producing a plurality of electromagnetic beams, a plurality of beam controllers positioned to receive a respective one of the plurality of electromagnetic beams and direct the respective electromagnetic beam into the region of overlap; and a system controller in electrical communication with each of the plurality of the beam controllers. Each beam controller controls at least one of the phase, amplitude and polarization of a respective one of the plurality of electromagnetic beams in response to control signals from the system controller. The result is a non-periodic pattern formed within the region of overlap by the interference of a plurality of electromagnetic beams in response to the control signals from the system controller. The invention also relates to a method for producing a non-periodic pattern in a region of overlap.