Abstract: A method for producing a uniform metal coating on a substrate consisting of (1) selecting one or more metals to be coated onto the substrate wherein the metals are soluble in a molten salt when heated, (2) preparing a bath consisting of the dissolved metal-molten salt, (3) inserting a substrate into the bath, and (4) decreasing the temperature at the substrate to a level at which the metal will precipitate out of solution onto the substrate. Multiple coatings can be made by repeating the method using the same or different metal-molten salt systems. Deposition can be enhanced by adding more salt to the bath to increase precipitation of the metal onto the substrate or by introducing additional metal into the bath by electrolysis, either by electrowinning or electrorefining. The metal coating can be patterned by localized heating of the metal coating in the metal-molten salt bath to reverse deposition or by masking areas on the substrate prior to deposition.

Abstract: A biochemical procedure for diagnosis of three important properties of cells in a biopsy or blood sample: tumor type i.e., the tissue type that has become neoplastic; tissue of origin if the tumor has arisen from a metastasis; and degree of malignancy. The procedure can also be used to obtain antibodies which can be used to determine tissue of origin by immunostaining and to detect tumor antigens appearing in blood by radioimmunoassay.The procedure consists of isolating and analyzing components of a specific subcellular fraction referred to here as the "nuclear matrix". The nuclear matrix consists of proteins specific to different cell types and nuclear matrix associated DNA. The electrophoretic pattern of the proteins and restriction endonuclease digested DNA is unique and reproducible within a particular cell type and is therefore useful in diagnosing cell type. Changes in these patterns following transformation to a malignant phenotype provide additional diagnostic information.

Abstract: A non-invasive method and apparatus of reshaping the cornea to correct hyperopia, keratoconus, or myopia is described. The central stroma of the cornea is heated by microwave electromagnetic energy to the shrinkage temperature of collagen. The microwave applicator for heating stroma comprises an open-ended, coaxial antenna driven at 2450 MHz with apparatus for surface cooling of the cornea by flow of saline transverse to the antenna axis.

Abstract: Apparatus for measuring the interfacial impedance in an electrochemical cell having a pair of electrodes in contact with an electrolyte medium that includes circuitry for measuring the interaction current flowing between the electrodes at a series of predetermined external impedance values and an analyzer for determining the interfacial impedance based on the current measurements.

Abstract: Two-dimensional surface-emitting diode laser arrays are described that take advantage of both the advanced state of development of linear laser arrays with conventional cleaved end faces and the rapid development of Si heat sink technology. A hybrid array consists of linear arrays of edge-emitting lasers that are mounted in grooves with flat bottoms and 45.degree. sidewalls etched in the top of a Si substrate containing microchannels for fluid flow on the backside. The 45.degree. sidewalls of the top Si grooves are coated with a highly reflecting metallic layer. These 45.degree. mirrors deflect the laser emission from the cleaved end faces of the linear laser arrays by 90.degree. so the emission is normal to the array surface. Use of the integral microchannel heat sink in the bottom of the Si substrate provides excellent heat removal capabilities for high power density operation.

Abstract: An elongate body having a longitudinal axis oriented transverse to fluid flow. The body is disposed within the viscous sublayer of the turbulent boundary layer flow across a wall, the body having a plane of symmetry passing through the longitudinal axis of the body and normal to the wall. Torsional springs support the body for deflections about the longitudinal axis and deflections are measured. The angular deflections about the longitudinal axis are substantially linearly related to shear stress on the wall.

Abstract: Disclosed is a heterodimeric T lymphocytes receptor subunit. The subunit consists of variable, joining, constant, transmembrane, and cytoplasmic regions.The structure, amino acid, and nucleotide sequence of the lymphocyte receptor subunit were determined using cDNA clones derived from a functional murine cytotoxic T lymphocyte clone. The genes corresponding to these cDNA are expressed and rearranged specifically in T cells and have significant sequence homologies to immunoglobulin V and C genes.T cell receptor subunits may be produced from the cDNA clones. The protein molecules may be further used for the production of T-cell clone specific antibodies.

Abstract: Electrochemical microsensors formed of a substrate containing means for sensing potential or current, including active and passive electronic devices and electronic circuits, and a micromachined structure containing at least one cavity overlying the sensing means, wherein the structure and substrate are bonded together at a temperature less than about 400.degree. C., in the absence of high voltage fields, using means not requiring highly planarized surfaces. A wide variety of materials can be utilized for both the substrate and overlying structure.Diverse embodiments are possible, having in common a cavity containing a chemically sensitive material and means for sensing potential or current.The resulting structural organization of materials transduces a chemical signal, such as concentration, to an electrical signal, which is then "processed" by the underlying FET or metallic connections.

Abstract: Disclosed is a heterodimeric T lymphocyte receptor comprising an alpha and a beta subunit. Each subunit consists of a signal peptide, variable, joining, constant, transmembrane, and cytoplasmic regions. The two subunits are connected by a disulfide bond between cysteine residues located between the constant and transmembrane region.The structure, amino acid, and nucleotide sequence of the lymphocyte receptor were determined using cDNA clones derived from a functional murine cytotoxic T lymphocyte clone. The genes corresponding to these cDNA are expressed and rearranged specifically in T cells and have significant sequence homologies to immunoglobulin V and C genes.Both the T cell receptor protein and its subunits may be produced from the cDNA clones. The protein molecules may be further used for the production of T-cell clone specific antibodies.

Abstract: X-ray detection systems based upon the nonlinear optical properties of multiple quantum well (MQW) semiconductor structures is described. X-rays generate carriers which change the index of refraction of the MQW material. Light from a probe beam may be scattered or reflected off the MQW structure and modulated by the change in refractive index caused by the carriers generated by the incident x-ray photons. A planar and microetalon approach is illustrated.

Abstract: The density of charge entrained in fluids such as oils in transformer systems, capacitors, cables, pumps and fuel transfer systems is measured by introducing the oil into a conductive container which expands in volume to receive the fluid without expelling any fluid. The container is shielded by a grounded conductor which prevents inducement of charge on the container by external sources. By measuring the current between the conducting expandable container and the surrounding shield and accounting for the effects of the charge induced on the outer wall of the container by its own induced voltage, the net charge entrained in the fluid as it is brought into the container is deduced. Extraneous effects of conduction and electrokinetic currents are automatically excluded from the measurement. The oil is then automatically returned to the transformer system by the contraction of the conductive container so that the measurement can be repeated without accumulating an inventory of fluid.

Abstract: A highly-parallel processing system in which a number of processing elements are interconnected by a network, and are also connected to a system bus and are controlled by a central processing unit. Each processing element includes a memory, and all of the memories in the processing elements form at least part of the memory available to the CPU. The processing elements normally execute programs in MIMD mode, and the CPU or another unit can interrupt them to execute a SIMD instruction. The network allows for transmission of variable length messages and also for combining messages when received at a common processing element.

Abstract: A coordination complex comprising a radionuclide selected from the class consisting of radioactive isotopes of Tc, Ru, Co, Pt and Re and an isonitrile ligand of the formula:(CNX)R,where X is a lower alkyl group having 1 to 4 carbon atoms, wherein R is selected from the group consisting of COOR.sup.1 and CONR.sup.2 R.sup.3 where R.sup.1 can be H, a pharmaceutically acceptable cation, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms. R.sup.2, and R.sup.3 can be H, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and R.sup.2 and R.sup.3 can be the same of different is disclosed. Kits that can be used to form these complexes are also disclosed.

Abstract: New soluble preceramic polymers formed by reacting B.sub.10 H.sub.14-n R.sub.n, (where R is a lower alkyl group having from 1 to about 8 carbon atoms, a substituted or unsubstituted cycloalkyl group having from 3 to about 8 carbon atoms, a substituted or unsubstituted lower alkenyl group having from 2 to about 8 carbon atoms, or a substituted or unsubstituted lower aryl group having from 6 to about 10 carbon atoms, and n is a number from zero to about six) with a diamine in an organic solvent are disclosed. Preferably the diamine has the formulaR.sup.1 R.sup.2 N-R.sup.3 -NR.sup.4 R.sup.5where R.sup.1, R.sup.2, R.sup.4 and R.sup.5 are H, a lower alkyl group having from 1 to about 8 carbon atoms, a substituted or unsubstituted cycloalkyl group having from 3 to about 8 carbon atoms, a substituted or unsubstituted lower alkenyl group having from 2 to about 8 carbon atoms, a substituted or unsubstituted lower aryl group having from 6 to about 10 carbon atoms, or a di- or triorganosilyl. R.sup.

Abstract: An osmium-catalyzed method of addition to an olefin. In the method of asymmetric dihydroxylation of the present invention, an olefin, a chiral ligand, an organic solvent, water, and aamine oxide and an osmium-containing compound are combined. In the method of asymmetric oxyamination of the present invention, an olefin, a chiral ligand, an organic solvent, water, an amine derivative and an osmium-containing compound are combined. In the method of asymmetric diamination of the present invention, an olefin, a chiral ligand, an organic solvent, a metallo-chloramine derivative or an amine derivative and an osmium-containing compound are combined. In one embodiment, an olefin, a chiral ligand which is a dihydroquinidine derivative or a dihydroquinine derivative, acetone, water, N-methyl morpholine N-oxide and osmium tetroxide are combined to effect asymmetric dihydroxylation of the olefin.

Abstract: An analysis of LEU3, a leucine-specific regulatory locus encoding a factor for control of RNA levels of a group of leucine-specific genes, is provided.DNA sequence analysis of a clone of LEU3 shows that it contains an open reading frame of 886 amino acids. There are three regions of particular interest: a cluster of acidic amino acids that are located in the C-terminal half of the coding region, a region with a repeated cysteine motif, and a region of partial homology with MATalpha2. A LEU3-dependent DNA binding activity is demonstrated to interact with homologous portions of the 5'-region of LEU1 and LEU2.

Abstract: The invention relates to visible-laser deposition reactions of metal containing oxyhalide and carbonyl vapors, such as, chromyl chloride vapor, CrO.sub.2 Cl.sub.2, or cobalt carbonyl, Co.sub.2 (CO).sub.8, for direct writing of metal containing opaque patterns on various substrates (Si, SiO.sub.2, GaAs and glass). Deposition at low laser power is by photolysis of adsorbed reactant molecules. Higher powers initiate deposition photochemically and continue it with a combined photolytic/pyrolytic reaction, simultaneously inducing a solid-phase conversion of the deposited film. Mixed Cr.sub.2 O.sub.3 /CrO.sub.2 or cobalt thin films of 1-nanometer to several-micrometer thickness, as well as 1-millimeter-long single crystals of Cr.sub.2 O.sub.3 or cobalt, can be grown with this process, the former at rates up to 3 .mu.m/s. Thin chromium oxide films produced in this manner are strongly ferromagnetic.

Abstract: A process for improving the swelling resistance of a titanium-modified austenitic stainless steel that involves a combination of rapid solidification and dynamic compaction techniques.

Abstract: Spatial light modulators which use a substrate having a buried channel charge-coupled device (CCD) formed therein, wherein the amount of charge in the charge storage wells associated with the electrodes of the CCD is controlled by an electrically or optically addressed data signal. The level of charge in such charge storage wells controls the electric field beneath the electrodes so that the intensity of electromagnetic energy (e.g., light) directed through The CCD is spatially modulated by the charge levels in the charge storage wells in accordance with the Franz-Keldysh electroabsorption effect.

Abstract: A method and resultant device is described for fabricating iridium silicide Schottky IR detectors in which a thin intermediate film of platinum is formed between the conventional iridium outer layer over a p-type silicon substrate with or without an n-type guard ring. After thermal treatment, an iridium platinum silicide region is formed in the silicon substrate. The unreated iridium/platinum outside the device region is removed using a dry-etching process.