Patents Assigned to Massachusetts Institute Technology
  • Patent number: 4814690
    Abstract: Devices and analytical techniques are disclosed for measuring the spatial profile of permittivity of a material by multiple wavenumber interrogations. Electrode structures are disclosed which define a number of different fundamental wavelengths (or wavenumbers). Spatially periodic interrogation signals (of temporary frequency ".omega.") from the electrode structures are attenuated to varying degrees by the material undergoing analysis, depending upon the wavenumber ("k"), thereby permitting the derivation of a composite dielectric profile.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: March 21, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: James R. Melcher, Mark C. Zaretsky
  • Patent number: 4813762
    Abstract: A diffractive lenslet array receives light from multiple lasers. The lenslet array is spaced apart from a partially reflecting mirror by a distance Z=nd.sup.2 /.lambda. where n is an integer or half integer, .lambda. is the laser wavelength and d is the spacing of the lenslets in the array. In a preferred embodiment the apparatus is a unitary design in which the lenslets are etched into one surface of a substrate and a parallel surface is coated to form the partially reflecting mirror. The lenslets abut one another to produce a fill factor (percentage of array containing light) close to one and each of the lenslets is a multistep diffractive lens. Diffractive speading over a round trip distance from lasers to mirror and back again causes feedback light from a single lenslet to couple into adjacent lenslets.
    Type: Grant
    Filed: February 11, 1988
    Date of Patent: March 21, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: James R. Leger, Wilfrid B. Veldkamp, Miles L. Scott
  • Patent number: 4813049
    Abstract: The laser has three regions p-n-n+ or n-p-p+ of magnetic element alloyed Group II-VI elements such as Cd, Hg, and Te doped with an element having a high atomic radius such as Sb or In. The magnetic element may be Mn or Fe. Vapor phase epitaxy is used to create a substrate having graded energy band gap characteristic across its thickness. A two-step liquid phase epitaxy process is used to grow an active layer and a passive layer to create the laser heterostructure. The index of refraction of the active region is higher than the indexes of refraction of the substrate and passive regions. The graded energy band gap and high doping of the substrate region results in a very low resistance which minimizes a temperature rise resulting from joule heating at high current densities. The relationship of the indexes of refraction of the layers result in double sided optical confinement to support lasing. In a semimagnetic semiconductor such as HgMnTe, the coefficient dE.sub.
    Type: Grant
    Filed: September 23, 1987
    Date of Patent: March 14, 1989
    Assignee: Massachusetts Institute of Technology
    Inventor: Piotr Becla
  • Patent number: 4810646
    Abstract: Three dimensional glucan matrix compositions are prepared by separating growing Saccharomyces cerevisiae yeast from its growth medium, subjecting the yeast with cell walls intact to aqueous hydroxide and treating the insoluble glucan with acetic acid to alter the .beta.(1-6) linkages. The glucans have viscosity characteristics dependent upon the strain of Saccharomyces cerevisiae utilized and are useful as stabilizer or thickeners.
    Type: Grant
    Filed: November 28, 1984
    Date of Patent: March 7, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Spiros Jamas, ChoKyun Rha, Anthony J. Sinskey
  • Patent number: 4810663
    Abstract: An integrated circuit device including a link point for electrically connecting a plurality of metal layers, comprising a first metal layer, a link insulating layer and a second metal layer. Diffusion barrier may be employed between the link insulator layer and each of the first metal layer and the second metal layer. The metal layers are connected by exposing the link point to a low-power laser for a relatively long pulse width.
    Type: Grant
    Filed: May 6, 1986
    Date of Patent: March 7, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Jack I. Raffel, John A. Yasaitis, Glenn H. Chapman, Mark L. Naiman, James A. Burns
  • Patent number: 4805456
    Abstract: An accelerometer is provided by a sample mass suspended in a central area of a support by pairs of resonating arms. One pair of arms lies on one axis through the sample mass. Another pair of arms lies on a second axis through the sample mass perpendicular to the one axis. Acceleration of the mass and support is detected by a measured change in resonant frequency of the arms of a pair. The measured change in resonant frequency is the magnitude of the acceleration and the axis along which the pair of arms lies provides the direction of the acceleration. Orthogonal components of acceleration are simultaneously measured by the pairs of arms lying on perpendicular axes. Electrostatic force-rebalance techniques and other known techniques for measuring acceleration in a direction perpendicular to the axes of the pairs of arms are readily incorporated to provide a third direction measurement of acceleration. The accelerometer is fabricated in a monolithic process which employs micromachining techniques.
    Type: Grant
    Filed: May 19, 1987
    Date of Patent: February 21, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Roger T. Howe, Shih-Chia Chang
  • Patent number: 4806621
    Abstract: A novel series of articles useful as medical devices, implants and protheses are provided which utilize poly(iminocarbonate) polymeric matrices. These articles are biocompatible, have excellent mechanical properties and degrade into non-toxic residues after introduction in vivo. The articles may be formed in any desired dimensions and configuration and may take specific shape as biodegradable sutures or as orthopedic appliances such as bone plates and the like.
    Type: Grant
    Filed: January 21, 1986
    Date of Patent: February 21, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Joachim Kohn, Robert S. Langer
  • Patent number: 4802491
    Abstract: Myocardial electrical stability is assessed based on the derivation of an alternating ECG morphology index from a series of heartbeats. The ECG electrical signal waveform is digitized at a plurlaity of sample points for each of the series of beats. Sample point matrices from the digitized ECG signals are constructed and the alternating energy at each of the sample points for the series of beats is computed. The alternating energy over the entire set of sample points is summed to generate the total alternating energy. This total alternating energy is normalized with respect to the energy of the average waveform, the normalized value being the alternating ECG morphology index. Animal studies indicate a high negative correlation between cardiac electrical stability and the alternating ECG morphology index.
    Type: Grant
    Filed: July 30, 1986
    Date of Patent: February 7, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Cohen, Joseph M. Smith
  • Patent number: 4800100
    Abstract: A method and apparatus is described for combined deposition of thin films of materials from an ion beam source and a molecular beam source in a single reactor.
    Type: Grant
    Filed: October 27, 1987
    Date of Patent: January 24, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Nicole Herbots, Olof C. Hellman
  • Patent number: 4798437
    Abstract: Discrete segments of an analog optical wave signal are collected in individual waveguides of a waveguide array. In the waveguide array, the optical signal is processed to provide an analysis of the signal or to control the signal. The signal can be analyzed by Mach-Zehnder interferometers which can provide an indication of the distance of a subject from the array. By controlling the dielectric constants of the waveguides electronically, the array can serve as an aberration free focusing lens or as an aberration compensation lens. Rapid electronic control of the focal length of the lens makes the lens particularly applicable to automatic focusing systems, systems which view only objects within a selected range of distances from the array, and the compiling of in focus segments to form a wide depth of field image.
    Type: Grant
    Filed: September 9, 1986
    Date of Patent: January 17, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert H. Rediker, Frederick J. Leonberger, Darryl P. Greenwood
  • Patent number: 4799192
    Abstract: A content addressable memory cell includes two storage field effect transistors of opposite conductivity type with their gates connected in common. A single write transistor is connected between the common gates and a bitline for storing a potential on the gates from the bitline.
    Type: Grant
    Filed: August 28, 1986
    Date of Patent: January 17, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Jon P. Wade, Charles G. Sodini
  • Patent number: 4794556
    Abstract: In-phase and quadrature components of a waveform are generated by sampling the waveform at a rate of four times the center frequency of the frequency band for which components are generated. The samples are digitized and applied to a digital 90.degree. all-pass phase-splitting network. Each pair of output samples is generated as a function of input samples delayed by an even number of time instants through a first all-pass branch and delayed by an odd number of time instants through a second all-pass branch. A common network may form both branches by switching coefficients of a multiplier and alternating the output between in-phase and quadrature samples. The waveform may be shifted from a higher freqeuncy by a mixer and may be filtered prior to sampling.
    Type: Grant
    Filed: September 19, 1984
    Date of Patent: December 27, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: Charles M. Rader
  • Patent number: 4792353
    Abstract: A consolidated metal-ceramic composite comprises a first phase of particles of aluminum oxide or a solid solution based on aluminum oxide uniformly distributed in a second matrix phase wherein the second matrix phase is non-reactive with aluminum oxide and contains a sufficient amount of titanium carbide at the interface between the first and second phase to prevent a chemical reaction at the interface during consolidation at the liquidus temperature and which exhibits good mechanical properties with regard to strength and toughness at high temperatures up to about 1200.degree. C.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: December 20, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Bruce M. Kramer, David M. Dombrowski, Dennis Gonseth, Minyang Yang, Stephen P. Kohler
  • Patent number: 4791490
    Abstract: The detector includes a focusing lens for focusing pulsed laser light reflected from an object onto a fiber optic array. The fiber optic array is configured to receive a two-dimensional image from the focusing lens and to convert the two-dimensional image into a line image. A streak camera responsive to light from the fiber optic array provides time resolution for the light from each of the fibers in the array. A two-dimensional detector records the light output from the streak camera and electronics store data and process information to construct three-dimensional images.
    Type: Grant
    Filed: July 2, 1987
    Date of Patent: December 13, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Frederick K. Knight, Kenneth Kalata
  • Patent number: 4789724
    Abstract: A method for preparation of very pure anhydride copolymers with high yield. The anhydride copolymers, consisting of aromatic and aliphatic diacids are formed by melt condensation of individually prepared, pure, isolated prepolymers. The method of preparation is characterized by high yield, reproducibility, polymer purity and controlled composition, and is a short and convenient procedure. The polyanhydrides produced by the disclosed method are particularly well suited to biomedical applications requiring low levels of toxic or inflammatory contaminants and physical and mechanical properties which closely conform to manufacturing specifications.
    Type: Grant
    Filed: October 17, 1986
    Date of Patent: December 6, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Abraham J. Domb, Robert S. Langer
  • Patent number: 4788634
    Abstract: A resonant forward converter at a switching frequency of 10 MHz provides a small volume point-of-load converter for distributed power systems. The leakage inductance of a transformer is made negligibly small relative to the magnetizing inductance of the transformer. This enables a resonant controllable switch on the primary side of a transformer and a secondary side rectified diode to be switched either on or off at the same time. The capacitance across the primary side switch and the secondary side diode rings with a resonant inductor connected in parallel with the transformer. Both the switch and diode, therefore, have zero voltage switching transitions. Further, the resonant inductor being connected in parallel with the transformer provides a resonant ring that is independent of load.
    Type: Grant
    Filed: June 22, 1987
    Date of Patent: November 29, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Martin F. Schlecht, Leo F. Casey
  • Patent number: 4787900
    Abstract: Process for forming a multilayer blood vessel prosthesis. Each layer is formed from bioreplaceable materials which include those produced by contacting collagen with an aminopolysaccharide and subsequently covalently crosslinking the resulting polymer, polymers of hydroxyacetic acid and the like. Cross flow filtration molding and wet extrusion molding are two processes which are particularly useful for forming the inner layer of the blood vessel prosthesis. The outer layer of the blood vessel prosthesis is preferably formed by freeze drying a dispersion of the bioreplaceable material onto the inner layer(s). The disclosed blood vessel prosthesis is a multilayer structure with each layer having a porosity and other physicochemical and mechanical characteristics selected to maximize the effectiveness of the blood vessel. The prosthesis functions initially as a thromboresistant conduit with mechanical properties which match those of the adjacent natural blood vessel.
    Type: Grant
    Filed: January 12, 1987
    Date of Patent: November 29, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: Ioannis V. Yannas
  • Patent number: 4786718
    Abstract: Experiments designed to define the differences between the 21 oncogene of DNA isolated from human bladder cancer cells and its corresponding proto-oncogene are described herein. By a series of in vitro recombinations, the difference was initially isolated to a 350 kb segment of DNA; sequencing defined the difference as a change in the Gly.sup.12 codon causing the p21 protein of the oncogene to contain valine at a location where the p21 protein of the proto-oncogene contained glycine. Assays for detecting carcinogenesis based on such differences are also described. In one type of assay, a restriction enzyme specific for either the altered or non-altered DNA segment of the genes are employed to detect carcinogenesis. In another type of assay, seralogical reagents, such as antibody specific for either p21 protein expressed from the proto-oncogene or oncogene, or a common site therein, are described.
    Type: Grant
    Filed: August 8, 1985
    Date of Patent: November 22, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert A. Weinberg, Clifford J. Tabin, Scott M. Bradley
  • Patent number: 4784722
    Abstract: A method and apparatus for forming a monolithic surface emitting laser diode array by providing vertical partly light transmissive mirror surfaces opposite parabolic light reflective mirror surfaces formed adjacent the active buried layer of a heterostructure diode laser. The mirror surfaces are preferably formed using a mass-transport heating process. Other mirror shapes may be formed in accordance with the invention.
    Type: Grant
    Filed: October 19, 1987
    Date of Patent: November 15, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Zong-Long Liau, James N. Walpole
  • Patent number: RE32782
    Abstract: A system for establishing, in vivo, the strength of bone in a live being such as, for example, a horse. The system permits determination of the speed of travel of sound through the bone and the strength of the bone is assessed on the basis of said speed of travel.The questions raised in reexamination request No. 90/000,815, filed 07/22/85, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e).
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: November 15, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: George W. Pratt, Jr.