Abstract: A method for configuring a surgical guide and an associated implant. The implant and surgical guide are for maxillofacial osteosynthesis. Three-dimensional models of the pre- and post-operative anatomy are used to define attachment points. These attachment points are used to determine a structure for the implant and surgical guide.

Abstract: Systems and methods for planning delivery of an object via a catheter, such as transseptal delivery of a prosthetic mitral valve to a patient's heart are disclosed.

Abstract: Certain aspects relate to a two-part surgical guide system for use in surgical procedures such as osteotomies. Certain aspects provide a first part including a contact surface configured to conform to a portion of an anatomy of the patient to substantially restrict movement of the first part with respect to the anatomy of the patient. The first part further includes guiding elements configured to receive reference pins and guide placement of the reference pins in the anatomy of the patient. Certain aspects further provide a second part, separate from the first part. The second part includes apertures. Each aperture is configured to receive a reference pin and substantially restrict movement of the second part with respect to the anatomy of the patient. The second part further includes a functional element for guiding a procedure on the anatomy of the patient.

Abstract: Systems and methods of fluid or air passageway cross-sectional area determination in an anatomy are disclosed. In some examples, the methods may include generating a model of a structure based on a plurality of images of the structure, the structure comprising at least one fluid or air flow path. In some examples, the methods may also include identifying an obstruction element in the model of the structure, the obstruction element affecting the at least one fluid or air flow path in the model. In some examples, the methods may also include determining a region of the at least one fluid or air flow path for flow analysis.

Abstract: Systems and methods of valve quantification are disclosed. In one embodiment, a method of mitral valve quantification is provided. The method includes generating a 3-D heart model, defining a 3-D mitral valve annulus, fitting a plane through the 3-D mitral valve annulus, measuring the distance between at least two papillary muscle heads, defining an average diameter of at least one cross section around the micro valve annulus, and determining a size of an implant to be implanted.

Abstract: Systems and methods of fluid passageway cross-sectional area determination in an anatomy are disclosed.

Abstract: A method and system for providing secure delivery, transport, modification, exchange of digital design and build files that have been bundled into a digital asset within a complex digital supply chain. The system also provides for quality standards when the digital asset is used to manufacture a physical part, and provides for secure feedback to stakeholders for the purpose of digital logistics, data analytics, or liability. The system includes, but is not limited to, manufacturing, licensing, modification and delegation policy, generating authorization certificates, authenticating manufacturing devices and provide qualitative and quantitative file consumption data.

Abstract: A method and system for providing secure delivery, transport, modification, exchange of digital design and build files that have been bundled into a digital asset within a complex digital supply chain. The system also provides for quality standards when the digital asset is used to manufacture a physical part, and provides for secure feedback to stakeholders for the purpose of digital logistics, data analytics, or liability. The system includes, but is not limited to, manufacturing, licensing, modification and delegation policy, generating authorization certificates, authenticating manufacturing devices and provide qualitative and quantitative file consumption data.

Abstract: A system and method for automatically reducing rigid body motion in a digital simulated model of an object, where the simulated model represents a simulated build of the object using additive manufacturing.

Abstract: Embodiments of this application relate to connectors configured for coupling to a hollow structure, for joining hollow structures together, and/or for joining a hollow structure to a functional element. A connector may be configured to couple to one or more hollow structures, and may be further configured to couple to one or more functional elements. Exemplary connectors comprise a shell and a plug.

Abstract: Systems and methods for planning delivery of an object via a catheter, such as transseptal delivery of a prosthetic mitral valve to a patient's heart are disclosed.

Abstract: A method for configuring a surgical guide and an associated implant. The implant and surgical guide are for maxillofacial osteosynthesis. Three-dimensional models of the pre- and post-operative anatomy are used to define attachment points. These attachment points are used to determine a structure for the implant and surgical guide.

Abstract: Systems and methods for planning delivery of an object via a catheter, such as transseptal delivery of a prosthetic mitral valve to a patient's heart are disclosed.

Abstract: A system and method for detecting, based on a simulation of a build of an object using additive manufacturing, if the build of the object would be flawed or would fail during actual additive manufacturing of the object is provided.

Abstract: Systems and methods of valve quantification are disclosed. In one embodiment, a method of mitral valve quantification is provided. The method includes generating a 3-D heart model, defining a 3-D mitral valve annulus, fitting a plane through the 3-D mitral valve annulus, measuring the distance between at least two papillary muscle heads, defining an average diameter of at least one cross section around the micro valve annulus, and determining a size of an implant to be implanted.

Abstract: Disclosed herein are perforated structures and methods for their manufacture. The perforated structures comprise zones of perforations, which are optimized for controlling the flow of gas or liquid through the perforated structure. The perforated structures may be configured for use as molds and for manufacture by additive manufacturing processes.

Abstract: The present disclosure relates to fixation devices. Certain embodiments provide a fixation device for insertion into bone. The fixation device includes a body comprising threads along an outer surface of the body. The fixation device includes one or more blades movably coupled to the body. The one or more blades are configured to move between at least a first position and a second position. In the first position, the one or more blades are retracted into the body. In the second position, the one or more blades are deployed out of the body for insertion into the bone.

Abstract: Certain embodiments described herein relate to systems and methods for determining implant configuration or design of implants by taking into account soft tissues and utilizing patient-specific simulations of activities of daily living.

Abstract: Methods and devices for improving airflow distribution in treatment of respiratory conditions are disclosed. According to various embodiments, blocking devices may be used to redirect air away from healthy portions of the lung to diseased portions so that inhaled medication may be more effectively delivered to the patient.

Abstract: The present disclosure relates to an eyewear assembly that is configured for fast and easy removal or exchange of lenses. The eyewear assembly comprises a connector that may be inserted into a frame front in order to hold the lenses in place, and removed from the frame front in order to release the lenses.