Abstract: Customized surgical guide for guiding a bone implant to a predetermined location on the bone during a surgical procedure, wherein the guide comprises a body comprising at least one implant contacting surface and at least one patient specific bone contacting surface, wherein the implant contacting surface is arranged to contact the implant for ensuring a unique and stable fit between the guide and the implant, and wherein the bone contacting surface is arranged to contact the bone for ensuring a unique and stable fit of a combination of the guide and the implant on the predetermined location on the bone.

Abstract: A system and method for calibrating a laser scanning system is provided. Various embodiments involve the use of a calibration plate with reference markings which is positioned to receive a directed beam in a set of known laser scanner positions. The directed beam forms a laser spot on the calibration plate, and the laser spot is captured using an image acquisition assembly such as a digital camera along with a motorized mount. The movement of the image acquisition assembly may be coordinated with the movement of the laser scanner to track the laser spot across the plate. After photographing various positions, actual laser spot coordinates are deduced from their position relative to the known positions of the reference markings.

Abstract: Systems and methods are provided for constructing a statistical shape model from a set of training shapes. In one embodiment, two shapes in the training set can be parameterized to a common base domain. Correspondence between the shapes can be evaluated using shape-specific data, such as, for the case of anatomical shapes, anatomical curves and/or anatomical landmarks. In evaluating correspondence, the shape-specific data about the second shape can be mapped to the shape-specific data about the first shape, and the mapping can be optimized based at least in part on a deformation energy of the mapping.

Abstract: The invention relates to surgical guides which are of use during reconstructive bone surgery for guiding a surgical instrument or tool. More particularly, the guides are characterized in that they are fitted to the implant rather than to the bone.

Abstract: The invention discloses a high-precision zinc-based alloy electrode wire, the external shell thereof consisting of: Zn: 70.5-95%; Cu: 2.5-27%; X: 0.02-4.0%; Y: 0.002-0.4%, and unavoidable impurities; where, X refers to any two kinds of metals selected from Ni, Ag, Cr, Si and Zr, and the weight percentage of each of these two kinds of metals is 0.01-2.0%; and Y refers to any two kinds of metals selected from Ti, Al, Co, B, and P, and the weight percentage of each of these two kinds of metals is 0.001-0.2%; the ?-phase in a metallurgical structure of the external shell is above 80 wt %. The invention also provides a method for manufacturing the electrode wire, which has high surface smoothness of the cut metal workpieces to improve the cutting precision. The method has simple process, high maneuverability, less steps, so as to facilitate large-scale and automated production.

Abstract: The invention relates to surgical guides which are of use during reconstructive bone surgery for guiding a surgical instrument or tool. More particularly, the guides are characterized in that they are fitted to the implant rather than to the bone.

Abstract: Provided herein is a method for generating and manufacturing a surgical guide for guiding a surgical intervention on a bone of a patient, and surgical guides obtainable by said method. The guides provided herein comprise an anatomy engagement surface or contact points for contacting with the first bone, and further comprise a support surface configured for contacting a second bone of the patient, over a certain range of motion of said second bone.

Abstract: The application relates to methods for manufacturing an object from a powder by selective sintering. More particularly, the methods described herein involve the step of selecting a polymer wherein the density of the crystalline phase of said polymer is equal to or lower than the density of the amorphous phase of said polymer.

Abstract: The application provides molds for the manufacture of intraluminal endoprostheses and methods for their manufacture. In particular embodiments, the methods comprise the steps of providing a 3D model of the mold, meshing the model, manufacturing a mold based on said meshed 3D model. Also provided herein are methods for manufacturing an endoprosthesis using said mold.

Abstract: Method for manufacturing a bone pin for connection to a bone, particularly for fixing an implant to a bone, the bone pin having an implant contacting part arranged to contact the implant in connected situation and a bone contacting part arranged to engage the bone in connected situation, wherein the method comprises the steps of:—providing bone information which is indicative for the bone which the bone contacting part is arranged to engage;—providing a bone contacting part which is customized on the basis of the bone information for engaging said bone;—providing an implant contacting part; and—assembling the bone contacting part and the implant contacting part for manufacturing the pin.

Abstract: A flexible unit cell is disclosed. The flexible unit cell is a single unit that can be repeated and interconnected to create a flexible design such as a covering for an object or person. The flexible unit includes a rigid portion and a flexible connection portion. Flexible units connect via the flexible connection portion to form a flexible design that can move and flex based on the connection of the flexible connection portions between flexible units. Further, the rigid portions of the flexible units may not be connected, allow such movement. The flexible unit is designed such that a flexible design made using such flexible units maintains a degree of rigidity so it can keep a shape of a surface of an object, but also maintains enough flexibility to conform to the surface even if the object bends or moves. Further disclosed are processes for manufacturing such flexible unit cells.

Abstract: The application provides customized aortic stent and stent graft devices and methods for the manufacture thereof. The customized aortic stent or stent graft are patient-specific in that they conform to at least part of the ascending aorta, aortic arch and/or thoracic aorta.

Abstract: Systems and methods of valve quantification are disclosed. In one embodiment, a method of mitral valve quantification is provided. The method includes generating a 3-D heart model, defining a 3-D mitral valve annulus, fitting a plane through the 3-D mitral valve annulus, measuring the distance between at least two papillary muscle heads, defining an average diameter of at least one cross section around the micro valve annulus, and determining a size of an implant to be implanted.

Abstract: The present invention provides a method for creating a personalized digital planning file for simulation of dental implant placement. After planning, the digital representation in a plaster model may be used to design and produce dedicated surgical templates to assist the surgeon in transferring the implant plan to a patient during medical intervention.

Abstract: A patient-specific tibial pin guide for placement on a tibia during a joint arthroplasty procedure on a patient is disclosed. The tibial pin guide includes a patient-specific inner surface having a first offset portion and a second offset portion. The first offset portion is configured to be offset from and mimic a first bone surface. The first offset portion of the patient-specific inner surface is shaped to form a gap to accommodate soft tissue overlying a proximal surface of the tibia of the patient. The second offset portion of the patient-specific inner surface is shaped to provide clearance for a patella tendon of the patient. The tibial pin guide also has a first patient-specific contact area configured for direct bone registration without intervening soft tissue and a second patient-specific contact area that is configured for direct bone registration without intervening soft tissue. The second patient-specific contact area is non-contiguous with the first patient-specific contact area.

Abstract: Embodiments of this application relate to systems and methods which allow for 3-D printed objects, such as eyeglasses and wristwatches, for example, to be customized by users according to modification specifications that are defined and constrained by manufacturers. These modification specifications may be constrained by the manufacturers based on factors relating to the printability of a modified design.

Abstract: Described herein are guiding instruments for use in surgical procedures involving the positioning of a bone plate. Furthermore methods for the manufacture of such instruments and methods for positioning a bone plate are also provided.

Abstract: Provided herein are patient-specific surgical guiding tools for positioning on a socket of a ball-and-socket joint, e.g. a glenoid cavity. The guiding tools comprise a central contact element fitting within the socket and one or more lateral contact elements fitting on the rim of the socket. The guiding tools allow accurate positioning of surgical tools such as alignment elements, according to a pre-operational planning. Methods for the manufacture and use of said guiding tools are also provided.

Abstract: A low-boron-oxygen cutting line for one-way wire winding and a manufacturing method are provided. A core material comprises 55-65 wt % of copper, 0.001-0.03 wt % of boron, 0.05-1.0 wt % of other elements which are at least two of titanium, iron, silicon, nickel, manganese, aluminum, tin, phosphorus and rare earth, less than 0.5 wt % of inevitable impurity elements, and an allowance of zinc; and a surface comprises 35.0-45.0 wt % of copper, 0.001-3.0 wt % of oxygen, 0.0005-0.5 wt % of other elements, at least two of which are titanium, iron, silicon, nickel, manganese, aluminum, tin, phosphorus and rare earth, less than 0.5 wt % of inevitable impurity elements, and an allowance of zinc. The cutting line has improved mechanical properties and strengthened discharge properties, and can cut irregularly shaped materials or those hollowed in the middle.

Abstract: The present application relates to surgical guiding tools that may be used for guiding a surgical instrument during bone surgery. A surgical guiding tool may include a body including one or more clamps configured to attach the surgical guiding tool to one or more portions of the bone, wherein a first clamp of the one or more clamps includes a snap-fit portion including a flexible structure for increasing a clamping force of the first clamp and allowing ease of removal of the surgical guiding tool from the bone. The surgical guiding tool may further include at least one aperture for guiding a surgical instrument. The present application further provides methods for manufacturing surgical guiding tools and uses of the tools for placement onto a bone.