Abstract: The present invention relates to transgenic plants with altered photorespiration and improved CO2 fixation as well as a method of producing said transgenic plants. Particularly, the transgenic plants show an improved growth rate, productivity and energy conversion efficiency. This method can be successfully applied to many agricultural crop plants with nutritional and medicinal uses.

Abstract: A photonic element for a quantum information processing device contains a high-purity silicon layer. The high-purity silicon layer contains integrated rare-earth element (REE) dopants at a concentration of 1019 cm?3 or less. An optical transition between the lowest crystal field levels of the REE dopants integrated in the high-purity silicon layer exhibits a homogeneous linewidth of 1 MHz or less at a temperature of 4 K or less. A method for producing such a photonic element is also disclosed.

Abstract: The present solution relates to animal behaviour modulation of at least one first animal to be carried out on a device attached to a second animal. The device comprises a memory, at least one sensor, a processor, and a signal generator. The method comprises: storing, in the memory, at least one extracted characteristic feature of training data of at least one monitored physical quantity in at least one degree of freedom in momentum, specific to at least one behaviour of the second animal and/or at least one local environmental condition related to the second animal; monitoring, by the at least one sensor, the at least one monitored physical quantity of the second animal and/or the at least one local environmental condition related to the second animal; determining, by the processor, a type of behaviour of the second animal; and generating, by the signal generator, a warning signal.

Abstract: The invention relates to a method of culturing an epithelial cell on a solid surface.

Abstract: The invention relates to a method of producing a fibrillary dry adhesive material having a plurality of fibrils. Furthermore, the invention relates to a fibrillar dry adhesive material in particular having liquid super-repellency.

Abstract: A magnetic memory device includes a conductive line extended in a first direction and a magnetic track line provided on a top surface of the conductive line and extended in the first direction. The magnetic track line includes a domain injection portion and a line portion, which is extended from the domain injection portion in the first direction. The domain injection portion has a tapered shape in an opposite direction of the first direction. The conductive line has a linewidth in a second direction, and the first and second directions are parallel to the top surface of the conductive line and are perpendicular to each other. Below the domain injection portion, a first linewidth of the conductive line remains constant in the opposite direction of the first direction.

Abstract: A magnetic memory device includes a conductive line extended in a first direction, a magnetic track line provided on the conductive line and extended in the first direction, and a non-magnetic line provided on the magnetic track line and extended in the first direction. The magnetic track line includes a lower magnetic layer and an upper magnetic layer stacked on the conductive line, an exchange coupling layer between the lower and upper magnetic layers, and a spacer layer between the exchange coupling layer and the upper magnetic layer. The exchange coupling layer is in contact with a bottom surface of the spacer layer, and the lower and upper magnetic layers are antiferromagnetically coupled with each other by the exchange coupling layer.

Abstract: The present invention relates to a method for producing a site -specifically serine ADP-ribosylated protein or peptide being, comprising: (a) subjecting a protein or peptide comprising or consisting of an amino acid sequence comprising two or more serines, wherein at least one serine is phosphorylated and at least one serine is non-phosphorylated, to a serine ADP-ribosylation reaction. The present invention also relates to a site-specifically serine ADP-ribosylated protein or peptide produced by the method of the invention.

Abstract: The present invention relates to rhodamine-type fluorophores being present in two states, a cell-permeable non-florescent form and a fluorescent form. The present invention also relates to use of the fluorophores in staining and live cell fluorescence imaging. The compounds have general formula (10) or the general formula (10?).

Abstract: Provided are a method and a device for characterizing a resonator element, a method and a device for providing an optical frequency reference, a LIDAR system and a gas sensing system. The method includes coupling a laser light into the resonator element, the resonator element having multiple carrier resonances for the carrier frequency of the laser light.

Abstract: Method for automatic focusing and astigmatism correction for a specific microscope setup, in particular an electron microscope, the microscope being at least adjustable in microscope parameters a working distance, a stigmator in a x-direction and a stigmator in a y-direction, the method comprising the steps: a) capturing a first image of a sample with a first working distance perturbation and capturing a second image of the sample with a second working distance perturbation around a current working distance and current stigmator settings; b) selecting n subareas of the first image and n subareas of the second image, n?1, wherein an i-th subarea of the first image and an i-th subarea of the second image form an i-th input patch pair, 1?i?n; c) processing each i-th input patch pair and receiving an i-th correction term comprising a correction to the current working distance, stigmator in x-direction and stigmator in y-direction; d) receiving an output correction term as a function of all the correction terms; e

Abstract: Disclosed herein is an engineered lipid-based vesicle optionally used for delivery of one or more payloads. The vesicle comprises a nanotube dimer or complex embedded with a lipid bilayer of the lipid-based vesicle. Also described herein are compositions, e.g., pharmaceutical compositions, and kits comprising the engineered lipid-based vesicle. In additional embodiments, further described herein are use of the engineered lipid-based vesicle for treating a disease or condition, for delivery to a target, or for labeling of a cell.

Abstract: A method of creating a local oscillator light beam LO for a phase-resolved spectroscopy measurement comprises the steps of providing a first measuring light beam (1) and a second measuring light beam (2) being aligned to each other, creating the local oscillator light beam LO by an optical non-linear interaction of a first portion (1A) of the first measuring light beam (1) and a first portion (2A) of the second measuring light beam (2) in an optical nonlinear medium (20), and superimposing the local oscillator light beam LO, a second portion (1B) of the first measuring light beam (1) and a second portion (2B) of the second measuring light beam (2) with a predetermined mutual phase relationship, for providing a sample light beam (3) for the phase-resolved spectroscopy measurement. The local oscillator light beam LO and the second portions (1B, 2B) of the first and second measuring light beams (1, 2) are superimposed with a displaced Sagnac interferometer (10).

Abstract: A semiconductor photomultiplier module (20; 30; 40) comprises a first semiconductor chip (21; 31; 41) disposed in a first plane and comprising an array (21.1) of single-photon avalanche diodes (SPAD), a second semiconductor chip (22; 32; 42) disposed in a second plane and comprising a first part of an electronic read-out circuit, and a third semiconductor chip (26; 36; 46) comprising a second part of the electronic read-out circuit, wherein the first semiconductor chip (21; 31; 41) and the second semiconductor chip (22; 32; 42) are arranged in a stacked relationship and vertical electrical interconnects (23) are arranged to electrically interconnect the first semiconductor chip (21; 31; 41) with the second semiconductor chip (22; 32; 42).

Abstract: The present invention relates to the use of a vehicle for specific molecular targeting of Langerin+ cells, wherein the vehicle is capable of specifically binding to a Langerin+ cell, said vehicle comprising (a) at least one carrier and (b) at least one saccharide moiety-based conjugate for a targeted cargo delivery into a Langerin+ cell, as well as pharmaceutical compositions and uses comprising the inventive vehicle.

Abstract: The quantum device comprises a transmission structure, wherein based on its geometrical arrangement, interference and quantum collapse, the transmission structure is designed such that quantum waves emitted by at least two bodies, for example, by thermal excitation, are passed preferentially to a subset of these bodies, without the need for a magnetic field to be applied.

Abstract: The current disclosure relates to methods for treating ovarian cancer based on specific antigen expression of the cancer. Furthermore, the expressed antigen may be used in immunotherapeutic methods for treatment of the ovarian cancer. Aspects of the disclosure relate to immunotherapies targeting CT45 polypeptides, methods for treating ovarian cancer based on CT45 expression, and kits for detecting CT45 polypeptides and nucleotides.

Abstract: A method and system that utilizes an admissible heuristic to determine the fastest-path between two points on a road map is disclosed. The method and system are based in part on a set of separators disposed on the map and represented by line segments, either independent or organized into hierarchical tree structures and based on recursive spatial subdivision. A preprocessing step computes a vector of values per road junction based on the separators that is then stored with the map and used to efficiently compute a high-quality heuristic to be used at a query stage. The heuristic scales well to any map size, resulting in a very efficient determination of fastest-path queries between points at all distances. The implementation is economically feasible and the resulting query speeds are significantly faster than other known heuristics and other state-of-the-art systems used for computing fastest-paths on maps.

Abstract: The present invention relates to a method for producing cytidine 5?-monophospho-N-acetyl-neuraminic acid (CMP-Neu5Ac, 1) from low-cost substrates N-acetyl-D-glucosamine (GlcNAc), pyruvate, cytidine and polyphosphate in a single reaction mixture with a set of optionally immobilized or optionally co-immobilized enzymes comprising N-acylglucosamine 2-epimerase (AGE), an N-acetylneuraminate lyase (NAL), an N-acylneuraminate cytidylyltransferase (CSS), a uridine kinase (UDK), a uridine monophosphate kinase and a polyphosphate kinase 3 (PPK3). Further, said process may be adapted to produce Neu5Acylated i.e. sialylated biomolecules and biomolecules including a saccharide, a peptide, a protein, a glycopeptide, a glycoprotein, a glycolipid, a glycan, an antibody, and a glycoconjugate, in particular, an antibody drug conjugate, and a carbohydrate conjugate vaccine, or a flavonoid.

Abstract: The invention relates to a linear drive unit comprising a first and second actuator element, a guiding unit configured to enable a linear relative movement between both actuator elements, a first and second power unit, each attached to the first actuator element and configured to provide the second actuator element with a respective first and second driving force, and a control unit for controlling both power units and configured to control the first and second driving force such that the first driving force can be different from the second driving force. The invention further relates to a telescope comprising a linear drive unit as well as to a method of aligning such telescope.