Abstract: A method of fabricating a component (1) comprises the steps of providing precursor material in a working medium, creating acoustic forces and positioning the precursor material in the working medium under the effect of the acoustic forces, so that a material distribution is formed, which has a shape of the component to be fabricated, and subjecting at least one of the material distribution and the working medium to a fixation, so that the precursor material of the material distribution or the working medium surrounding the material distribution is bound, wherein the step of creating the acoustic forces includes generating an acoustic interference pattern (5), and the material distribution (4) is formed by moving the precursor material (2) towards energy extrema of the acoustic interference pattern (5). Furthermore, an apparatus (100) for fabricating a component (1) is described.

Abstract: A method where a propeller is set into locomotion relative to a medium at least partially surrounding the propeller. An actuator induces a rotation of the propeller relative to the medium and about a rotational axis of the propeller, and the propeller converts its rotational movement into locomotion relative to the medium. The aspect ratio of at least one cross-section of the propeller is three or more. Also a helical or modifiedly helical propeller for converting rotational movement of the propeller into locomotion of the propeller relative to a medium at least partially surrounding the propeller, where the aspect ratio of at least one cross section of the propeller is three or more. And a method of producing a propeller, including the step of providing a plate extending along the helical axis, where the aspect ratio of at least one cross section of the plate is three or more.

Abstract: The present invention refers to methods of increasing the catalytic efficieny of Hydrogen Evolution Reactions (HER) electrocatalysts with a low external magnetic field. The present invention further includes electrochemical cells having an external magnetic field. The electrocatalyst is a metal or a compound with partially filled d-orbitals, more preferred a ferromagnetic or paramagnetic material with partially filled d-orbitals.

Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.

Abstract: The present invention relates to means and methods for conjugating/attaching target molecules such as proteins to a label and/or carrier. Specifically, the present invention provides a complex comprising a metal cation coordinating (i) nitrate as a metal cation ligand and (ii) a metal cation chelating domain comprising a chelating ligand and a label and/or carrier. This complex can be used for attaching a label and/or a carrier to a target molecule, preferably a protein. The attachment of the label or carrier via the complex of the invention involves the replacement of the metal cation ligand with a coordinating group of the target molecule so that a product complex with the target molecule as primary ligand in the coordination sphere of the metal cation is formed. Accordingly, the present invention also provides for uses and methods involving the attachment of a label and/or carrier to a target molecule.

Abstract: The present invention relates to transgenic plants with altered photorespiration and improved CO2 fixation as well as a method of producing said transgenic plants. Particularly, the transgenic plants show an improved growth rate, productivity and energy conversion efficiency. This method can be successfully applied to many agricultural crop plants with nutritional and medicinal uses.

Abstract: Disclosed are systems and techniques for extracting user body shape (e.g., a representation of the three-dimensional body surface) from user behavioral data. The behavioral data may not be explicitly body-shape-related, and can include shopping history, social media likes, or other recorded behaviors of the user within (or outside of) a networked content delivery environment. The determined body shape can be used, for example, to generate a virtual fitting room user interface.

Abstract: The present invention relates to means and methods for conjugating/attaching target molecules such as proteins to a label and/or carrier. Specifically, the present invention provides a complex comprising a metal cation coordinating (i) a metal cation ligand being a carbonate selected from CO32? and HCO3— and (ii) a metal cation chelating domain comprising a chelating ligand and a label and/or carrier. This complex can be used for attaching a label and/or a carrier to a target molecule, preferably a protein. The attachment of the label or carrier via the complex of the invention involves the replacement of the metal cation ligand with a coordinating group of the target molecule so that a product complex with the target molecule as primary ligand in the coordination sphere of the metal cation is formed. Accordingly, the present invention also provides for uses and methods involving the attachment of a label and/or carrier to a target molecule.

Abstract: Disclosed are a device, system and method for animal tracking. The tracking device comprises a tracker processing component, an energy component, a transmitting component, and a securing component. The system comprises the tracking device, a receiving device and a server. The method comprising securing the tracking device to an animal, transmitting an identification of the animal, receiving the transmission via the receiving device, modifying it and forwarding it to the server, where the modified transmission is logged and analyzed to determine animal positions.

Abstract: The present invention relates in a first aspect to a plug flow tubular bioreactor having an integral or multi-part tube adapted for cultivation, and, optionally, infection, viral transduction, or transfection of eukaryotic cells. In a further aspect, the present invention relates to a plug flow tubular bioreactor system comprising the plug flow tubular bioreactor according to the present invention. Further, the present invention relates to a method for preparing virus particles, vectors, cells or other molecules including toxic molecules using the plug flow tubular bioreactor or the system according to the present invention. Finally, the present invention relates to the use of a plug flow tubular bioreactor for the preparation of virus particles, vectors including viral vectors, cells including modified cells or other molecules including toxic molecules.

Abstract: The present invention relates to a device for separation of plasma or serum from a blood sample from a small blood volume (e.g. capillary blood). The device comprises a separation member, an extraction member and a housing. The extraction member comprises a base and one or more microstructures protruding from and being integrally formed with said base, wherein said one or more microstructures are configured to extract plasma or serum from said separation member by capillary forces. The present invention further provides methods for separating plasma or serum using the device according to the present invention. Similarly, also methods for analyzing one or more proteins and/or metabolites contained in plasma or serum that is separated using a device according to the present invention are provided.

Abstract: The invention relates to a modular polypeptide comprising a first partial effector sequence comprising a first part of a circular permutated halotag protein connected to a sensor module sequence, which is connected to a second part of a circular permutated halotag protein. The sensor module is a single polypeptide or a polypeptide pair capable of undergoing conformational change from a first confirmation to a second confirmation depending on the presence or concentration of an analyte compound. The modular peptide is catalytically active in response to an environmental stimulus or in response to the sensor pair interacting. The invention further relates to nucleic acid sequences encoding the modular polypeptide, and to kits comprising same.

Abstract: The invention relates to a DEPFET comprising: a semiconductor substrate (100) of a first conduction type, which has a first main surface (101) and a second main surface (102), which are opposite one another; a source terminal region (1s) of a second conduction type on the first main surface (101); a drain terminal region (1d) of a second conduction type; a channel region (10), which is arranged between the source terminal region (1s) and the drain terminal region (1d); a gate electrode (11), which is separated from the channel region (10) by a gate insulator (6); a rear activation region (104) of a second conduction type, which is formed on the second main surface (102); and a substrate doping increase region (2) of a first conduction type, which is formed at least under the source terminal region (1s) and under the channel region (10), the substrate doping increase region (2) having a signal charge control region (20) of the first conduction type below the gate electrode (11), in which signal charge control

Abstract: An interferometer apparatus includes a beam splitter arranged for splitting an input beam into a first beam propagating along a first interferometer arm including a deflection mirror and a second beam propagating along a second interferometer arm including a deflection mirror. The first and second interferometer arms have an identical optical path length. A beam combiner is arranged for recombining the first and second beams into a constructive output and a destructive output. In the first interferometer arm compared with the second interferometer arm, one additional Fresnel reflection at an optically dense medium is provided and a propagation of the electromagnetic fields of the first and second beams, when recombined by the beam combiner, results in a wavelength-independent phase difference of ? between the contributions of the two interferometer arms to the destructive output. Furthermore, an interferometric measurement apparatus and an interferometric measurement method are described.

Abstract: A computer-implemented method for shape deformation, comprising: obtaining an image; obtaining one or more positional constraints; determining a shape deformation/image map, based on the positional constraints; applying the shape deformation to the image; and outputting the image.

Abstract: The present invention relates in a first aspect to a method for the purification of biological macromolecular complexes. Typically, no chromatography steps are applied. That is, the present invention relates to a method for the purification of biological macromolecular complexes Furthermore, the present invention relates to a method for crystallization of biological macromolecular complexes comprising the step of purification as described followed by crystallization in a reservoir solution containing a water-soluble polymer. Furthermore, purified biological macromolecular complexes obtainable by the method according to the present invention are provided as well as crystallized biological macromolecular complexes. Finally, a method for determining the suitability of a candidate compound for inhibiting the 20S proteasome of an individual is provided.

Abstract: A method of detecting particles (1), e.g. proteins, after separation of particles based on their specific features, e.g. charge, size, shape, density, as series of single light scattering events created by the individual particles is described. The particles (1) are separated from each other along the separation path (11) and particles have specific arrival times at the target side depending on the particle features. The detecting step comprises an interferometric sensing of the light scattered at individual particles bound or transient in the detection volume (30). Parameters of the scattering light signals e.g. the interferometric contrast are analysed for obtaining specific particle features, e.g. size, mass, shape, charge, or affinity of the particles (1). Furthermore, a detection apparatus (100) being configured for detecting particles (1) is described.

Abstract: The present invention relates to an expression system for a genetically encoded protein synthesis inhibitor containing RNA N-glycosidase activity split into two components. The expression system can be combined with genetic targeting systems to achieve cell- and/or tissue-type-specific and/or temporally-specific control of protein synthesis in a host, particularly in a mammalian host.

Abstract: A method of magnetic resonance tomography includes arranging an object in a static magnetic field, subjecting it to radiofrequency (RF) pulses and magnetic field gradients for creating spatial encoding of magnetic resonance signals, acquiring the signals with at least two RF receive coils, each with a self-resonance frequency and a spatially restricted sensitivity profile, and reconstructing an object image. Spatial encoding of the signals by the gradients and the profiles is utilized, wherein the profile of at least one of the coils is subjected to a temporal sensitivity profile modulation while acquiring the signal. The self-resonance frequency of the at least one coil is set within a predetermined receive bandwidth of a constant resonance frequency value during the modulation. The reconstructing further utilizes the modulation for obtaining additional spatial information to the spatial encoding of the signals by the gradients. Furthermore, an MRI device is described.

Abstract: The invention relates to a method for separating chlorine from a gaseous anode outlet stream mass flow of an electrochemical cell reactor. In a first aspect, the method makes use of an absorption step, wherein an anode outlet stream mass flow of the electrochemical cell reactor is exposed to an organic solvent being essentially immiscible with water for achieving an exergy-efficient separation of chlorine and hydrogen chloride. In a further aspect, the method makes use of absorption step, wherein the anode outlet stream mass flow is exposed to an ionic liquid, wherein the hydrogen chloride is dissolved in said ionic liquid, thereby forming a gas flow containing essentially chlorine and a solution mass flow comprising the ionic liquid and the hydrogen chloride. The hydrogen chloride is desorbed from the solution mass flow in a desorption step.