Patents Assigned to McMaster University
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Patent number: 12372583Abstract: An approach to control or monitoring of battery operation makes use of a recurrent neural network (RNN), which receives one or more battery attributes for a Lithium ion (Li-ion) battery, and determines, based on the received one or more battery attributes, a state-of-charge (SOC) estimate for the Li-ion battery.Type: GrantFiled: October 8, 2021Date of Patent: July 29, 2025Assignees: The Trustees of Columbia University in the City of New York, McMaster UniversityInventors: Ephram Chemali, Matthias Preindl
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Patent number: 12372585Abstract: An approach to control or monitoring of battery operation makes use of an artificial neural network (ANN), which receives one or more battery attributes for a Lithium ion (Li-ion) battery, and determines, based on the received one or more battery attributes, a state-of-charge (SOC) and/or a state-of-health (SOH) estimate for the Li-ion battery. The ANN includes at least one of a recurrent neural network (RNN) and a convolutional neural network (CNN), and the series of values of the battery attributes includes at one of battery voltage values, battery current values, and battery temperature values.Type: GrantFiled: March 7, 2023Date of Patent: July 29, 2025Assignees: The Trustees of Columbia University in the City of New York, McMaster UniversityInventors: Ephram Chemali, Matthias Preindl
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Patent number: 12360115Abstract: Methods of determining the risk of an adverse cardiovascular event or death in a mammal are provided which include determining in a biological sample obtained from the mammal the level of a combination of biomarkers selected from a glucose metabolism biomarker, a heart function biomarker, a renal function biomarker and at least one biomarker of cardiac injury. A score is allotted based on the level of each biomarker, and the cumulative score is indicative of the risk of an adverse cardiovascular event.Type: GrantFiled: August 26, 2016Date of Patent: July 15, 2025Assignee: McMaster UniversityInventors: Peter Kavsak, Andrew Worster
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Patent number: 12343452Abstract: The present application discloses biofunctional surfaces that have self-assembled monolayers of fluorine groups with “built-in” functional groups promote targeted cell and biomolecule binding to the surface while reducing non-specific binding. Further, this application also relates to methods for preparing functional biomolecules, viruses and cells that can be covalently immobilized to prepare biofunctional surfaces.Type: GrantFiled: January 9, 2019Date of Patent: July 1, 2025Assignee: McMaster UniversityInventors: Tohid F. Didar, Maryam Badv, Zachary Cetinic, Amid Shakeri
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Patent number: 12344687Abstract: A novel synthetic functionalized backbone polymer is provided which is a polyanionic side-chain functionalized backbone polymer comprising a hydrophilic backbone polymer functionalized with an activated alkene or epoxy group. The functionalized backbone polymer may be combined with a free or protected thiol-containing compound to form a crosslinked hydrogel having biomedical application, and may additionally be combined with a hydrogel matrix to yield a hydrogel system useful for in vivo delivery of cells and other therapeutic agents.Type: GrantFiled: January 9, 2024Date of Patent: July 1, 2025Assignee: McMaster UniversityInventors: Sarah Alison Stewart, Harald Donald Helmut Stover, Michael Bradley Coulson
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Publication number: 20250101064Abstract: The present disclosure relates generally to the field of cancer immunotherapy. More particularly, the present disclosure relates to multivalent antibody recruitment molecules and methods of treating cancer using same.Type: ApplicationFiled: August 26, 2024Publication date: March 27, 2025Applicant: McMaster UniversityInventors: Anthony Rullo, Yonghong Wan, Benjamin Lake
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Publication number: 20240420573Abstract: System, methods, and other embodiments described herein relate to implementing cooperative management strategies. In one embodiment, a method includes determining a severity score and a risk area. The method may then determine whether vehicles should belong to a first vehicle set, which may perform a cooperative vehicle response action, or a second vehicle set, in which individual response actions may be performed. The method may then generate a cooperative response action or an individual response action corresponding to the cooperative or individual vehicle sets, provided such vehicle sets are not empty.Type: ApplicationFiled: June 15, 2023Publication date: December 19, 2024Applicants: Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Jidosha Kabushiki Kaisha, McMaster UniversityInventors: Seyhan Ucar, Hao Yang, Yashar Zeiynali Farid
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Publication number: 20240416950Abstract: A system and method is provided for implementing computer-controlled systems (e.g., vehicle safety and traffic management systems) based on compliance rates. A vehicle system and method are provided that estimate compliance rates in real-time, and have the capability to dynamically modify the computer-controlled instructions generated by a computer-controlled system (e.g., vehicle safety and traffic management systems) in a manner that improves compliance, and in-turn improves overall system performance. For example, a vehicle includes sensors receiving data from a plurality of communicative connected vehicles. The received data is associated with a real-time monitoring of traffic conditions for the vehicle. The vehicle also includes a controller device estimating a compliance rate in real-time based on the received data. The controller device of the vehicle also controls an automated operation of the vehicle using a modified computer-controlled instruction based on the estimated compliance rate.Type: ApplicationFiled: June 14, 2023Publication date: December 19, 2024Applicants: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA, McMaster UniversityInventors: Yashar ZEIYNALI FARID, Hao YANG, Seyhan UCAR
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Publication number: 20240388063Abstract: An optical grating comprising a refractive index with a periodic pattern that includes a base period ?0; a periodic sampling of the base period, with a first period ?1 and a first duty cycle p1, thereby defining a single-sampled grating (SSG); and a periodic sampling of the SSG, with a second period ?2 and a second duty cycle p2. The resulting dual-sampled grating (DSG) can have a reflection spectrum containing reflection peaks. If two DSGs having different reflection spectra share a common interface, a tunable optical filter can be produced, where electrical or heating means can cause a reflection peak of one spectrum to be shifted to coincide with a reflection peak of the other spectrum, thereby filtering the corresponding wavelength. By inserting between the two DSGs a gain medium and a phase-tuning medium, a laser source structure is realized. Either device can be produced by etching or stacking methods.Type: ApplicationFiled: July 26, 2024Publication date: November 21, 2024Applicants: HUAWEI TECHNOLOGIES CANADA CO., LTD., McMaster UniversityInventors: Xun LI, Chuanning NIU, Sangzhi ZHAO, Tan Huy HO
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Publication number: 20240375145Abstract: This disclosure relates to methods of making omniphobic materials which are physically and chemically modified at their surface to create hierarchically structured materials with both nanoscale and microscale structures that provide the omniphobic properties. Uses thereof, including as flexible tubular structures that repel contaminants are also disclosed herein.Type: ApplicationFiled: August 18, 2022Publication date: November 14, 2024Applicant: McMaster UniversityInventors: Tohid Didar, Leyla Soleymani, Shadman Khan
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Publication number: 20240359211Abstract: This application relates to omniphobic materials which are physically and chemically modified at their surface to create hierarchically structured materials with both nanoscale and microscale structures that provide the omniphobic properties. Methods of making such omniphobic surfaces with hierarchical structures and uses thereof, including as flexible films that repel contaminants are also disclosed in the application.Type: ApplicationFiled: July 10, 2024Publication date: October 31, 2024Applicant: McMaster UniversityInventors: Leyla Soleymani, Roderick Maclachlan, Sara Moetakef Imani, Yuting Chan, Tohid Didar
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Patent number: 12125216Abstract: Systems, methods and devices for detecting a presence of an analyte in a fluid sample are described herein. The devices include a microfluidic module having a microfluidic channel configured to receive the fluid sample at an inlet thereof and direct the fluid sample towards an outlet thereof. The devices also include an image sensor positioned removably abutting the microfluidic module. The image sensor is positioned laterally between the inlet and the outlet of the microfluidic channel and below a lower surface of the microfluidic channel. The image sensor is communicatively coupled to a processor that is configured to receive signal data from the image sensor. The devices also include a light source configured to direct light through the fluid sample and towards the image sensor as the fluid sample passes through the microfluidic channel. The image sensor receives the light and outputs the signal data to the processor.Type: GrantFiled: June 18, 2021Date of Patent: October 22, 2024Assignee: McMaster UniversityInventors: Qiyin Fang, Jessica Kun, Marek Smieja
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Publication number: 20240343872Abstract: This disclosure relates to superhydrophobic materials and/or surfaces comprising a shrinkable polymer substrate and at least one polysiloxane layer, wherein the materials and/or surfaces comprise microscale wrinkles and nanoscale features that form hierarchical structures. Methods of making and uses thereof are also disclosed herein.Type: ApplicationFiled: August 17, 2022Publication date: October 17, 2024Applicant: McMaster UniversityInventors: Tohid F. Didar, Leyla Soleymani, Liane Ladoucheur
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Publication number: 20240331531Abstract: An example operation includes one or more of receiving traffic data uploaded from vehicles that are currently operating within a geographic area via a computer network, generating a plurality of macroscopic fundamental diagrams (MFDs) for a plurality of sub-areas within the geographic area, respectively, based on the received traffic data, identifying a sub-area among the plurality of sub-areas which is congested based on the plurality of MFDs, and transmitting routing instructions to the vehicles within the geographic area to divert the vehicles away from the sub-area.Type: ApplicationFiled: April 28, 2023Publication date: October 3, 2024Applicants: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA, McMaster UniversityInventors: Yashar Zeiynali Farid, Hao Yang, Seyhan Ucar, Kentaro Oguchi
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Publication number: 20240331532Abstract: An example operation includes one or more of receiving traffic data from a plurality of transports that are currently in operation within a predetermined geographic area, partitioning a map of the predetermined geographic area into a plurality of partitions based on link states within the traffic data, generating a plurality of macroscopic fundamental diagrams (MFDs) for the plurality of partitions based on flow rates and link densities in the traffic data, and mitigating congestion within the predetermined geographic area based on the plurality of MFDs for the plurality of partitions.Type: ApplicationFiled: March 30, 2023Publication date: October 3, 2024Applicants: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA, McMaster UniversityInventors: Yashar Zeiynali Farid, Hao Yang, Seyhan Ucar, Kentaro Oguchi
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Publication number: 20240317660Abstract: The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted.Type: ApplicationFiled: June 23, 2022Publication date: September 26, 2024Applicant: McMaster UniversityInventors: Jakob Magolan, Xiong Zhang, Nicholas Jentsch, Mathew Piotrowski, Meghan Fragis, Jarrod Johnson, Lauren Irwin
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Patent number: 12078370Abstract: A district energy system includes at least one energy provisioning unit, an energy management controller; a thermal distribution network coupled to the energy provisioning units and to a plurality of coupling interfaces connectable to the associated HVAC system of buildings within a district, and an electrical distribution network coupled to the energy provisioning units and to the coupling interfaces. The coupling interfaces may include both heat pumps and heat exchangers at each building, to provide heating, cooling and enable harvesting of normally wasted thermal energy from the buildings for re-distribution. The controller can manage the selection and number of energy provisioning units (and their operational set points) coupled to the district thermal distribution network and the electrical distribution network to meet the thermal and electrical demands of the district while satisfying other operational goals such as the minimization of greenhouse gas emissions.Type: GrantFiled: April 19, 2021Date of Patent: September 3, 2024Assignee: McMaster UniversityInventors: James Scott Cotton, Kelton Friedrich, Vickram Lakhian, Saber Mohamed, Mohamed Yasser Abdelsalam, Jorge Chebeir, Jeff Girard
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Publication number: 20240272148Abstract: The present application is directed to methods of performing chemical reactions, including multi-step chemical reactions in which two or more of the reagents in the chemical reaction are incorporated or entrapped in a solid polymeric structure comprising pullulan. In certain embodiments, the chemical reaction or multi-step reaction serves as a sensor. Accordingly the present application is also directed to sensors for performing the methods of the application. In certain embodiments, at least one of the reagents is a biomolecule and the sensor is a biosensor. In certain other embodiments, the solid polymeric structure comprising pullulan and the reagents for performing a chemical reaction form a convenient device for performing a chemical reaction.Type: ApplicationFiled: February 9, 2024Publication date: August 15, 2024Applicant: McMaster UniversityInventors: Carlos Filipe, John D. Brennan, Robert Pelton, Sana Jahanshahi-Anbuhi, Yingfu Li
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Patent number: 12044669Abstract: An electrochemical sensor array for detecting analytes in water, including a frame; a plurality of sensor electrodes each mounted to the frame, including a free chlorine working electrode including a gold thin film and having a free chlorine sensing surface to be exposed to the water; and a reference electrode including a silver thin film and a silver and silver chloride layer and having a reference sensing surface to be exposed to the water. A method of manufacturing an electrochemical sensor array for detecting analytes in water, including forming a free chlorine electrode, including forming a gold thin film on a first base layer; forming a reference electrode, including forming a silver thin film on a second base layer and applying a silver and silver chloride paste to a portion of the silver thin film; and arranging the free chlorine electrode and the reference electrode on a common frame.Type: GrantFiled: December 16, 2021Date of Patent: July 23, 2024Assignees: McMaster University, 2055218 Ontario Inc.Inventors: Arif Ui Alam, Mohamed Jamal Deen
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Patent number: 12011422Abstract: Provided herein are novel synthetic compounds having the structure of formula (1), wherein X is a substituted or unsubstituted aromatic or heteroaromatic mono- or polycyclic ring system; and Y is substituted or unsubstituted C5-C10 alkyl or alkenyl group, or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium.Type: GrantFiled: May 27, 2022Date of Patent: June 18, 2024Assignee: McMaster UniversityInventors: Eric Brown, Omar M Elhalfawy, Nick Jentsch, Xiong Zhang, Jakob Magolan