Patents Assigned to McMaster University
  • Publication number: 20040249082
    Abstract: Siliceous materials were prepared by adding one or more additives, including one or more water soluble polymers, and derivatives thereof, as well as trifunctional silanes, to sols containing tetraalkoxysilanes derived from polyols. The polymers facilitate phase separation of the growing silica gel matrix, leading to high surface area self-supporting silica gels with cure occurring at ambient temperatures. The materials also show a significant reduction in shrinkage properties and significant protein stabilization abilities.
    Type: Application
    Filed: April 1, 2004
    Publication date: December 9, 2004
    Applicant: McMaster University
    Inventors: Zheng Zhang, Yang Chen, Jorge Cruz-Aguado, Richard J. Hodgson, Dina Tleugabulova, John D. Brennan, Michael A. Brook
  • Patent number: 6828025
    Abstract: A process for encapsulation of polar organic solvents with amphiphilic copolymer shell using controlled/living polymerization is provided for the first time. To encapsulate polar core-oils an amphiphilic polymer is required that has low interfacial tensions with both the oil phase and the water phase. For example, Poly(methyl methacrylate-co-poly(ethylene glycol) methacrylate) (PMMA-co-PegMA) was prepared in suspension polymerization conditions using atom transfer radical polymerization (ATRP). ATRP ensures that the water soluble comonomer, PegMA, is incorporated into every polymer chain throughout the polymerization reaction so that all chains possess the desired amphiphilic character. Crosslinking of PMMA-co-PegMA with diethylene glycol dimethacrylate (DegDMA) yielded hollow capsular particles at 31 mol % PegMA in the terpolymer.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: December 7, 2004
    Assignee: McMaster University
    Inventors: Mir Mukkaram Ali, Harald D. H. Stöver
  • Patent number: 6797533
    Abstract: A quantum well structure having an indium gallium arsenide phosphide (InGaAsP) quantum well active region has a low temperature grown indium phosphide (LT-InP) cap layer grown on it. Defects in the cap layer are intermixed into the quantum well active region by rapid thermal annealing to produce a blue shift in the active region. The blue shift increases as the growth temperature of the LT-InP cap layer decreases or as the phosphine flow rate during production of the LT-InP layer increases.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: September 28, 2004
    Assignee: McMaster University
    Inventors: David A. Thompson, Bradley J. Robinson, Gregory J. Letal, Alex S. W. Lee, Brooke Gordon
  • Publication number: 20040166592
    Abstract: The present invention relates to methods of immobilizing membrane-associated molecules within a sol-gel matrix. The membrane-associated molecule is embedded in the bilayer of a liposome. The molecule-liposome assembly remains functionally intact when it is immobilized within a protein and membrane-compatible sol-gel derived from polyol silane precursors or sodium silicate.
    Type: Application
    Filed: November 14, 2003
    Publication date: August 26, 2004
    Applicant: McMaster University
    Inventors: John D. Brennan, Michael A. Brook, Travis Besanger
  • Patent number: 6684702
    Abstract: A method for detecting an obstruction in a flow duct is provided. The method includes the steps of directing gas through at least one port of the flow duct, measuring a flow noise level of the gas directed through the at least one port, and comparing the noise level with a predetermined noise level. In the event that the flow noise level exceeds the predetermined noise level by at least a threshold amount, then the method includes the step of indicating the presence of an obstruction in the at least one port.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: February 3, 2004
    Assignee: McMaster University
    Inventor: Samir Ziada
  • Patent number: 6647800
    Abstract: The present invention provides a simple design for a temperature-insensitive extrinsic polarimetric strain sensor. The sensing element is a thin sheet of photoelastic material that is bonded to the test object. It is illuminated with linearly polarized light with the polarization direction at 45 degrees relative to the strain-induced fast and slow axes in the photoelastic material. The sensor measures the difference between the strains along these two orthogonal directions. The reduced sensitivity of the sensor to temperature results from the fact that the illumination is perpendicular to the surface of the test object. All polarization components that are parallel to the surface will experience identical refractive index changes due to thermal effects. Consequently, a measurement of the difference in strains along two directions in the surface plane is insensitive to temperature.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: November 18, 2003
    Assignee: McMaster University
    Inventors: Gonzalo De La Puente, Paul E. Jessop
  • Patent number: 6635104
    Abstract: Disclosed is a separation device for the separation of water vapour from a gas stream, comprising a water vapour separation membrane having a porous membrane, whose pores contain a water transfer material, the water transfer material including a first hydrophilic polymer and a second polymer which is interwoven with the first polymer.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: October 21, 2003
    Assignee: McMaster University
    Inventors: Elena N. Komkova, Alicja M. Mika, Ronald F. Childs
  • Patent number: 6627218
    Abstract: A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a spacer arm and a cationic amino group, and an appropriate co-lipid. The invention also includes the cationic lipids and mammalian plasmid DNA or other cells in admixture with the aqueous dispersion.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: September 30, 2003
    Assignees: The University of Tennessee Research Foundation, McMaster University
    Inventors: Leaf Huang, Richard M. Epand, Remo Bottega
  • Patent number: 6592648
    Abstract: A process of reduction of iron ore and/or waste oxides in the form of agglomerate containing carbonaceous reductant on the hearth of a furnace includes providing a bed of agglomerates on the hearth of a furnace, the bed having a height of at least about 40 mm and having at least four layers of agglomerates. The carbonaceous reductant contains sufficient volatile matter, the volatile matter having a weight of at least about 10% of the weight of the reductant. The bed of agglomerates is heated with a radiant heat source having a temperature of at least about 1450° C. to cause the top of the bed to reach a temperature in the range of 1350° C. to 1530° C. to 1500° C. to reduce iron oxides in the iron ore and/or waste oxides to metallic iron.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: July 15, 2003
    Assignee: McMaster University
    Inventors: Wei-kao Lu, Dianbing Huang
  • Patent number: 6566322
    Abstract: Disclosed are silicone polymer based compounds, which include a hydrophobic silicone polymer backbone and a hydrophilic component. The hydrophilic component may act as a chelating agent to bind a metal. The hydrophilic component may be hydrophilic prior to binding with a metal or after binding. Also disclosed are methods of making these compounds. The compounds are useful in a variety of applications.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: May 20, 2003
    Assignee: McMaster University
    Inventors: Michael A. Brook, Rodica-Sinziana Himmeldirk
  • Patent number: 6513390
    Abstract: The present invention provides a simple design for a temperature-insensitive extrinsic polarimetric strain sensor. The sensing element is a thin sheet of photoelastic material that is bonded to the test object. It is illuminated with linearly polarized light with the polarization direction at 45 degrees relative to the strain-induced fast and slow axes in the photoelastic material. The sensor measures the difference between the strains along these two orthogonal directions. The reduced sensitivity of the sensor to temperature results from the fact that the illumination is perpendicular to the surface of the test object. All polarization components that are parallel to the surface will experience identical refractive index changes due to thermal effects. Consequently, a measurement of the difference in strains along two directions in the surface plane is insensitive to temperature.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: February 4, 2003
    Assignee: McMaster University
    Inventors: Gonzalo De La Puente, Paul E. Jessop
  • Patent number: 6509032
    Abstract: A cationic lipid useful in transfection of cells with DNA is disclosed.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: January 21, 2003
    Assignee: McMaster University
    Inventors: Leaf Huang, Richard M. Epand, Remo Bottega
  • Patent number: 6461404
    Abstract: A ladle is equipped with properly positioned side and bottom injectors for enhanced steel decarburization in a vacuum tank degasser. To facilitate the circulation of liquid steel in the tank the bottom injectors are positioned in a common segment in order to create a single loop of liquid flow. To enlarge the surface area exposed to vacuum, and to increase the active surface area, supplementary gas flow is provided by side injectors located at the upper sidewall. The active surface area is enhanced by breaking bubbles released from side injectors.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: October 8, 2002
    Assignee: McMaster University
    Inventors: Gordon Irons, Diancai Guo
  • Patent number: 6406562
    Abstract: There is provided a method for treating the surface of metals such as nickel based or high alloy steels, austenitic and ferritic stainless steels, copper and aluminum alloys to increase their corrosion resistance by modification of the metal surfaces to inhibit cathodic corrosion processes. In a single step treatment process the metals are immersed into a heated aqueous composition containing a rare earth salt substantially free of any halide compound. Increased corrosion resistance is obtained using nitrates of yttrium, gadolinium, cerium, europium, terbium, samarium, neodymium, praseodymium, lanthanum, holmium, ytterbium, dysprosium, and erbium nitrates. The rare earth salt is present in the range from about 2% by weight to saturation of the solution. The composition includes a pH-modifying substance such as nitric acid to adjust the pH in the range 0.5 to about 6.5 to attack the surface to remove oxides facilitating deposition of the rare earth.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: June 18, 2002
    Assignee: McMaster University
    Inventors: Yucheng Lu, Michael Brian Ives
  • Patent number: 6386217
    Abstract: An assistive device for persons with an injured or disabled leg includes a main body comprising a crutch to which is pivotally attached a supporting structure. To assist the person in walking, the device can be used as crutch in the known manner, and the supporting structure is maintained in the same plane as the crutch. When the person wishes to be seated, one end of the device is placed on the seat adjacent the person and the supporting structure of the device is pivoted out of the plane of the crutch to provide a support for the opposite end.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: May 14, 2002
    Assignee: McMaster University
    Inventors: Barbara Cooper, Derek Clark, John Campa, Antonio Bellusci
  • Patent number: 6319516
    Abstract: A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a spacer arm and a cationic amino group, and an appropriate co-lipid. The invention also includes the cationic lipids and mammalian plasmid DNA or other cells in admixture with the aqueous dispersion.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: November 20, 2001
    Assignees: The University of Tennessee Research Corporation, McMaster University
    Inventors: Leaf Huang, Richard M. Epand, Remo Bottega
  • Patent number: 6287969
    Abstract: Disclosed herein is a method of forming a superconductor, comprising the steps of: providing a substrate and exposing the substrate to a first atmosphere, including precursors to form a first epitaxial layer segment. The first layer segment is then exposed to a second atmosphere, including precursors to form a second epitaxial layer segment, and the second layer segment is exposed to a third atmosphere including precursors to form a third epitaxial layer segment. Each of the first and third layer segments are each formed from a superconductor material and the second layer segment is formed from a material different from the first and third layer segments and the first, second and third layer segments have a collective thickness, the third layer segment having an outer surface with a roughness which is less than that of a single layer of the superconductor material with a thickness equal to the collective thickness.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: September 11, 2001
    Assignee: McMaster University
    Inventors: Robert A. Hughes, Patrick J. Turner, John S Preston
  • Patent number: 6273483
    Abstract: A robotic gripper for fixturing and manipulating a sheet of substantially rigid material, e.g. a sheet metal part, has three fingers with circumferential grooves thereon. Each of the fingers has three degrees of movement. The sheet metal part has at least one opening of a size suited to accommodate one of the fingers. The other fingers can engage the edges of other openings in the sheet metal part or the outside edge of the part. The fingers can be moved away from each other or towards each other respectively depending on the positioning of the fingers, whereby the sheet metal part is fixtured by means of the grooves of the fingers. By using three fingers each having three degrees of movement, and having grooves thereon, an object can be held and kinematically locked without the application of force.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: August 14, 2001
    Assignee: McMaster University
    Inventor: Gary M. Bone
  • Patent number: 6258276
    Abstract: Charged membranes comprise a porous substrate and a cross-linked polyelectrolyte or hydrogel located in the pores of the substrate and are useful in a variety of membrane separation processes, including pressure driven membrane separation, diffusion dialysis, Donnan dialysis, electrodialysis, electrochemical synthesis and prevaporation. Certain of the membranes are novel.
    Type: Grant
    Filed: October 18, 1996
    Date of Patent: July 10, 2001
    Assignee: McMaster University
    Inventors: Alicja M. Mika, Ronald F. Childs, James M. Dickson
  • Patent number: 6068711
    Abstract: There is provided a method for treating the surface of metals such as nickel based or high alloy steels, austenitic and ferritic stainless steels, copper and aluminum alloys to increase their corrosion resistance by modification of the metal surfaces to inhibit cathodic corrosion processes. In a single step treatment process the metals are immersed into a heated aqueous composition containing a rare earth salt substantially free of any halide compound. Increased corrosion resistance is obtained using nitrates of yttrium, gadolinium, cerium, europium, terbium, samarium, neodymium, praseodymium, lanthanum, holmium, ytterbium, dysprosium, and erbium nitrates. The rare earth salt is present in the range from about 2% by weight to saturation of the solution. The composition includes a pH-modifying substance such as nitric acid to adjust the pH in the range 0.5 to about 6.5 to attack the surface to remove oxides facilitating deposition of the rare earth. For aluminum alloys the pH is maintained between 4.5 to 6.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: May 30, 2000
    Assignee: McMaster University
    Inventors: Yucheng Lu, Michael Brian Ives