Patents Assigned to MED Institute
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Publication number: 20110009945Abstract: A method for deploying a stent delivery system having a blowmolded holder is provided. The stent is configured to expand from a first diameter to a second diameter. The holder is blowmolded to an inner surface of the compressed state. The holder contacts the inner surface and at least portions of side surfaces of the stent, and the holder and the stent have an interference fit therebetween. The deployment method includes delivering the compressed stent placed on the blowmolded holder and the holder into a predetermined deployment side. The deployment method further includes releasing the stent from interference with the holder and expanding the stent from the compressed stent to the expanded stent.Type: ApplicationFiled: September 21, 2010Publication date: January 13, 2011Applicants: Cook Incorporated, MED Institute Inc.Inventors: FRED T. PARKER, ANTHONY O. RAGHEB
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Publication number: 20110009848Abstract: A medical device is provided. The device includes a cannula with a lumen defined therethrough and an upper portion, a right side portion, a bottom portion, and a left side portion each substantially equally spaced from their respective neighboring portion around the circumferential surface of the cannula. The cannula additionally includes a plurality of apertures disposed through the distal end portion to provide communication from the lumen and a visually perceptible indicator that is configured to allow the cannula to be positioned at an appropriate rotational position within the patient.Type: ApplicationFiled: July 7, 2009Publication date: January 13, 2011Applicants: Vance Products Inc. d/b/a Cook Urological Inc., Med Institute, Inc, Sabin CorporationInventors: Bryan Woodard, James D. Purdy, David R. Wagner, Richard B. Sisken, Steven J. Charlebois, Gregory A. Frankland, Scott K. Philhower
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Patent number: 7867275Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: September 1, 2006Date of Patent: January 11, 2011Assignees: Cook Incorporated, MED Institute, Inc.Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, William D. Voorhees, III, Thomas G. Kozma
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Patent number: 7862605Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of a bioactive agent posited over at least one surface of the structure 12. Optionally, the device 10 can include at least one porous, preferably polymeric layer 20 posited over the layer 18 of bioactive agent, and can alternatively or additionally include at least one coating layer 16 posited on one surface of the structure 12, the at least one layer 18 of bioactive agent being posited in turn on at least a portion of the coating layer 16. The porous layer 20 and the coating layer 16 each provide for the controlled release of the bioactive material from the device 10. The structure 12 is preferably configured as a stent graft. The polymer of the porous layer 20 is preferably applied by vapor or plasma deposition.Type: GrantFiled: November 27, 2006Date of Patent: January 4, 2011Assignees: MED Institute, Inc., Cook IncorporatedInventors: Anthony O. Ragheb, Brian L. Bates, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III
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Publication number: 20100323052Abstract: The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice.Type: ApplicationFiled: August 27, 2010Publication date: December 23, 2010Applicants: Cook Incorporated, MED Institute, Inc.Inventors: DAVID E. ORR, William F. Moore
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Publication number: 20100312326Abstract: The present invention provides apparatus and methods for deployment of a modular stent-graft system. In one embodiment, a prosthesis comprises a first tubular graft comprising a layer of graft material, at least one lumen extending longitudinally therein, and a first fenestration extending through the layer of graft material. A layer of fenestration covering material attaches to the layer of graft material. The layer of fenestration covering material is disposed in the lumen of the first tubular graft and partitions the first fenestration from the lumen of the first tubular graft. A first non-stented opening is disposed proximal to the first fenestration and communicates with the first fenestration between the layer of graft material and the fenestration covering material. In use, a proximal end of a second tubular graft sealably engages the first non-stented opening, and the second tubular graft further extends through the first fenestration and into a branch vessel.Type: ApplicationFiled: July 22, 2010Publication date: December 9, 2010Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Timothy A.M. Chuter, Blayne A. Roeder, Steven J. Charlebois
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Patent number: 7846202Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, where the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 may be posited over the bioactive material layer 18, where the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: December 27, 2007Date of Patent: December 7, 2010Assignees: Cook Incorporated, Med Institute, Inc.Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, William D. Voorhees, III, Thomas G. Kozma
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Publication number: 20100292778Abstract: An expandable stent for use in a body vessel comprises a thin-walled tubular framework including two or more circumferentially adjacent end members extending in a longitudinal direction from an end of the framework. In a delivery configuration of the tubular framework, the end members have an interlocking configuration. Each end member has a first interlocking side and a second interlocking side, where the first interlocking side has a circumferentially directed protrusion and the second interlocking side has a circumferentially directed recess. The protrusion of a first end member mates with the recess of a second end member. In an expanded configuration of the tubular framework, the end members are disengaged from the interlocking configuration. Each end member may be an eyelet including an opening for a radiopaque rivet. A method of preparing the expandable stent for delivery into a body vessel is also described.Type: ApplicationFiled: May 15, 2009Publication date: November 18, 2010Applicant: MED Institute, Inc.Inventors: Blayne A. Roeder, Seoggwan Kim, Richard A. Swift
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Patent number: 7828840Abstract: This invention relates to medical devices and an angiotensin II type 2 (AT2) receptor antagonist compound, the medical device being adapted to release the AT2 receptor antagonist compound within a body of a patient. This invention also relates to medical devices and methods of treatment of disease, such as aneurysms and aortic dissection. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters.Type: GrantFiled: November 12, 2008Date of Patent: November 9, 2010Assignees: Med Institute, Inc., Cook IncorporatedInventors: David Paul Biggs, David D. Grewe, Anthony O. Ragheb, Patrick H. Ruane
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Patent number: 7815687Abstract: The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.Type: GrantFiled: December 17, 2008Date of Patent: October 19, 2010Assignee: Med Institute, Inc.Inventors: Clinton D. Bahler, Alan R. Leewood, Jichao Sun
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Patent number: 7811622Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: October 31, 2007Date of Patent: October 12, 2010Assignees: Cook Incorporated, MED Institute, Inc.Inventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, Thomas G. Kozma, William D. Voorhees, III
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Publication number: 20100249899Abstract: A stent graft for endovascular introduction into the pararenal region of the descending aorta. The stent graft has an elongate tubular body (10) with a proximal portion (12), a distal portion (16) of a diameter less than the proximal portion and a tapered central portion (14). A notional transverse clock face on the tubular body has 12 o'clock at a notional anterior longitudinal datum line. The stent graft has a scalloped cut out (26) centered at about 12:30 o'clock and a fenestration (28) at about 12:00 o'clock in the proximal portion and first and second fenestration assemblies which can be low profile side arms at about 2:15 o'clock and about 10:00 o'clock in the tapered central portion. The tapered central portion can have an arcuate side wall (30) so that the tapered portion has an outer face which is concave.Type: ApplicationFiled: March 26, 2010Publication date: September 30, 2010Applicants: Cook Incorporated, William A. Cook Australia Pty. Ltd., MED Institute, Inc.Inventors: Timothy A. Chuter, David Ernest Hartley, Blayne A. Roeder
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Patent number: 7799261Abstract: The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice.Type: GrantFiled: November 20, 2008Date of Patent: September 21, 2010Assignees: Cook Incorporated, MED InstituteInventors: David E. Orr, William F. Moore
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Patent number: 7799070Abstract: A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material.Type: GrantFiled: October 31, 2007Date of Patent: September 21, 2010Assignees: Cook Incorporated, MED InstituteInventors: Brian L. Bates, Anthony O. Ragheb, Neal E. Fearnot, William D. Voorhees, III, Thomas G. Kozma
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Patent number: 7799266Abstract: A method for manufacturing a stent delivery system having a holder and at least one stent configured to expand from a first diameter to a second diameter is provided. The manufacturing method includes compressing the stent to the first diameter, inserting the stent into a first tube, placing a second tube inside the first tube and inside an inner diameter of the stent. The second tube is airtight. The manufacturing method also includes applying pressure and heat suitable to the second tube, thereby blowmolding the second tube against the stent.Type: GrantFiled: December 16, 2008Date of Patent: September 21, 2010Assignees: Cook Incorporated, MED Institute Inc.Inventors: Fred T. Parker, Anthony O. Ragheb
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Patent number: 7780717Abstract: A stent graft introducer actuation assembly (1) having a fixed handle (3) and at least one sliding handle (5, 7), the sliding handle or handles telescoping within the fixed handle, and a winch arrangement (9) to retract the sliding handle into the fixed handle. There may be provided arrangements to give a mechanical advantage to the winch arrangement.Type: GrantFiled: April 26, 2007Date of Patent: August 24, 2010Assignees: MED Institute, Inc., William A. Cook Australia Pty. Ltd.Inventors: Werner Dieter Ducke, David Ernest Hartley, David D. Grewe
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Patent number: 7766953Abstract: A deployment system and method for an expandable stent are described. The deployment system includes an expandable stent in an unexpanded state and a first tubular sheath having one or more first flaps extending from a distal end thereof. The one or more first flaps overlie one or more first longitudinal portions of the stent. A second tubular sheath may overlie the first tubular sheath. The deployment method includes advancing a deployment system including an expandable stent in an unexpanded state to a treatment site in a body vessel. At the treatment site, one or more second longitudinal portions of the stent are radially expanded to partially deploy the stent, and then one or more first longitudinal portions of the stent are radially expanded to fully deploy the stent. Each of the first and second longitudinal portions preferably extends from a proximal end to a distal end of the stent.Type: GrantFiled: May 16, 2007Date of Patent: August 3, 2010Assignee: Med Institute, Inc.Inventors: James D. Purdy, Joseph M. Stewart, IV
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Patent number: 7753948Abstract: A beam is provided for intraluminal devices. The beam is defined by a first side surface and a second side surface. The first side surface is tapered at a different rate than the second side surface. One advantage of the beam is that strain which is normally concentrated in adjacent, interconnected bends is redirected onto the length of the beam. This may increase the fatigue life of intraluminal devices or may be used to fashion new structures with improved performance.Type: GrantFiled: June 15, 2006Date of Patent: July 13, 2010Assignee: Med Institute Inc.Inventors: Blayne A. Roeder, Alan R. Leewood
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Publication number: 20100161027Abstract: A stent includes a main body having proximal and distal ends, and at least one conformance strut coupled to the proximal end of the main body. A portion of the at least one conformance strut extends proximal to a proximal end of a graft material in a compressed delivery configuration, and further is aligned inside the proximal end of the graft material in an expanded deployed configuration. In the deployed configuration, the proximal conformance strut may at least partially encircle the graft material just distal to the proximal end of the graft material, which may reduce the likelihood of infolding at the proximal edge of the graft material and potential endoleaks.Type: ApplicationFiled: December 17, 2009Publication date: June 24, 2010Applicant: MED Institute, Inc.Inventor: David E. Orr
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Publication number: 20100148409Abstract: A method for manufacturing a stent delivery system having a holder and at least one stent configured to expand from a first diameter to a second diameter is provided. The manufacturing method includes compressing the stent to the first diameter, inserting the stent into a first tube, placing a second tube inside the first tube and inside an inner diameter of the stent. The second tube is airtight. The manufacturing method also includes applying pressure and heat suitable to the second tube, thereby blowmolding the second tube against the stent.Type: ApplicationFiled: December 16, 2008Publication date: June 17, 2010Applicants: Cook Incorporated, MED Institute, Inc.Inventors: Fred T. Parker, Anthony O. Ragheb