Abstract: An implantable medical device includes a functional unit, an introducer unit for introducing and/or navigating the functional unit in a lumen of body conduit(s) of a subject, and an elongated operable element connectable to a controller for operating the functional unit though the elongated operable element in a lumen of body conduit(s) of the subject. The functional unit, introducer unit, and elongated operable element may be in a slidable relationship for assembling and unassembling the implantable medical device in vivo. The implantable medical device is implantable, explantable, and operable in a lumen of body conduit(s) of a subject according to related methods.

Abstract: An occlusion catheter system for full or partial occlusion of a vessel includes an occlusion balloon. The balloon is positioned in a folded, uninflated configuration around a central shaft, a proximal shaft, and a distal shaft of the occlusion catheter system, having an outer diameter less than seven French. The balloon is constructed of a semi-compliant or non-compliant material and is sized to have a blown diameter between approximately ten percent to sixty percent greater than the inner diameter of the vessel, whereby an outer surface of the balloon comes into full diametric contact with an inner surface of the vessel upon partial inflation of the balloon and folds are formed in the outer surface of the balloon. The folds define flow channels with inner surfaces of the vessel or with portions of the outer surface of the balloon that allow partial blood flow past the balloon.

Abstract: Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, receiving the output signal from the at least one light detector with a processor and based on the received output signal, calculating the attenuance attributable to blood in a sample with a signal-to-noise ratio of at least 20-to-1; and determining a blood glucose level.

Abstract: The various embodiments of the method of the present invention include a method to improving or expanding the capacity of a sleep analysis unit or laboratory, a method sleep analysis testing a patient admitted for diagnosis or treatment of another primary medical condition while being treated or diagnosed for that condition, a method of sleep analysis testing a patient that cannot be easily moved or treated in a sleep analysis unit or laboratory and other like methods.

Abstract: An electrotherapeutic device for treating a visual disease using microcurrent stimulation is provided. The device includes a signal generator in which a waveform controller digitally controls a waveform signal source so as to generate a waveform in which one or more waveform parameters (e.g., pulse width, pulse period, pulse position, pulse coding, peak current amplitude, duty cycle, and/or pulse shape) are varied in accordance with a protocol for treating a visual disease. The device also includes an applicator connected to the signal generator and configured to apply the waveform to at least one stimulation point within an eye region.

Abstract: The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

Abstract: The present invention provides for a data acquisition system for EEG and other physiological conditions, preferably wireless, and method of using such system. The wireless EEG system can be used in a number of applications including both studies and clinical work. These include both clinical and research sleep studies, alertness studies, emergency brain monitoring, and any other tests or studies where a subject's or patient's EEG reading is required or helpful. This system includes a number of features, which enhance this system over other systems presently in the marketplace. These features include but are not limited to the having multiple channels for looking at a number of physiological features of the subject or patient, a built in accelerometer for looking at a subject's or patient's body motion, a removable memory for data buffering and storage, capability of operating below 2.

Abstract: The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to method of sleep diagnosis and treatment.

Abstract: Medical apparatuses for securing, protecting, retaining, and/or concealing various medical devices such as catheters or electrical leads are disclosed herein. The medical apparatus can be a garment which for use by a patient having a central venous catheter in place. Medical garments as disclosed herein can be used for a wide variety of medical devices attached to a patient, by implantation or otherwise, for varying lengths of time. Medical garments described herein may be used with any of a variety of medical devices which include or comprise one or more conduits used for medical treatment or diagnosis, including conduits which comprise catheters as well as electrical conduits such as electrical leads.

Abstract: The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.

Abstract: A radiation latency measurement system, having a pulse detector connected to a radiation detector mounted within a phantom that is configured to be positioned within a radiation treatment system which delivers a radiation dose to the radiation detector. The pulse detector has a first circuit that applies a high voltage bias to the radiation detector and a second circuit that amplifies the voltage signal from the radiation detector with a fixed gain first amplification stage and a variable gain second amplification stage. A first comparator receives the amplified signal and generates an output signal when the amplified signal exceeds a specified voltage level and a second comparator that processes and filters the output signal. The timing of receipt of the radiation dose signal may be compared to the position of the radiation detector in order to measure a radiation dose latency of the radiation treatment system.

Abstract: The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.

Abstract: A deformable image registration phantom, having a housing, an outer cylinder with a first diameter, a parallel eccentric inner cylinder with a second diameter smaller than the first diameter, a ball and socket mount, and a target. The target is mounted to the housing by way of the inner and outer cylinders and the ball and socket mount. The inner cylinder is rotatably mounted within the outer cylinder and the target is rotatably mounted, directly or indirectly, within the inner cylinder. The outer cylinder may be rotatably mounted within the housing and the ball and socket mount rotatably mounted within the inner cylinder. Alternatively, the outer cylinder may be rotatably mounted within the ball and socket mount and the ball and socket mount rotatably mounted within the housing.

Abstract: The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

Abstract: Transcatheterly implantable mammalian body conduit intralumenal device and lumen wall anchor assembly. Anchor includes: wire network, connector positioning wires having a secured and a released position, and a connector disposed at end of each wire. Anchor has: a compact-secured-configuration, an expanded-secured-configuration, an expanded-released-configuration. When the anchor is in the expanded-secured-configuration, the wire network exerts a force on conduit lumen wall and the connector positioning wires are the in secured position. When the anchor is in the expanded-released-configuration, the connector positioning wires are in the released position, and do not obstruct fluid flow axially through conduit. Device includes an interconnector that allows for the releasable interconnector of the connectors thereto. Device and anchor assembly can be explanted from the conduit.

Abstract: The present invention provides for a data acquisition system for EEG and other physiological conditions, preferably wireless, and method of using such system. The wireless EEG system can be used in a number of applications including both studies and clinical work. These include both clinical and research sleep studies, alertness studies, emergency brain monitoring, and any other tests or studies where a subject's or patient's EEG reading is required or helpful. This system includes a number of features, which enhance this system over other systems presently in the marketplace. These features include but are not limited to the having multiple channels for looking at a number of physiological features of the subject or patient, a built in accelerometer for looking at a subject's or patient's body motion, a removable memory for data buffering and storage, capability of operating below 2.

Abstract: The various embodiments of the method of the present invention include a method to improving or expanding the capacity of a sleep analysis unit or laboratory, a method sleep analysis testing a patient admitted for diagnosis or treatment of another primary medical condition while being treated or diagnosed for that condition, a method of sleep analysis testing a patient that cannot be easily moved or treated in a sleep analysis unit or laboratory and other like methods.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.