Patents Assigned to Medicure International, Inc.
  • Cardioprotective phosphonates and malonates
    Publication number: 20030120074
    Abstract: The present invention provides for pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) and to pyridoxine malonate analogues, such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)malonates), pharmaceutical compositions, and methods for treatment of cardiovascular and related diseases, and diabetes mellitus and related diseases.
    Type: Application
    Filed: October 28, 2002
    Publication date: June 26, 2003
    Applicant: Medicure International Inc.
    Inventor: Wasimul Haque
  • Cardioprotective phosphonates and malonates
    Publication number: 20030114677
    Abstract: The present invention provides for pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) and to pyridoxine malonate analogues, such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)malonates), pharmaceutical compositions, and methods for treatment of cardiovascular and related diseases, and diabetes mellitus and related diseases.
    Type: Application
    Filed: October 28, 2002
    Publication date: June 19, 2003
    Applicant: Medicure International Inc.
    Inventor: Wasimul Haque
  • Treatment of cerebrovascular disease
    Publication number: 20030114424
    Abstract: A method of treating a cerebrovascular disease, particularly stroke, is described. A method of treating a cerebrovascular disease includes administering pyridoxal-5′-phosphate, pyridoxal, pyridoxine, pyridoxamine, 3-acylated analogues of pyridoxal, 3-acylated analogues of pyridoxal-4,5-aminal, pyridoxine phosphonate analogues, or pharmaceutical compositions thereof.
    Type: Application
    Filed: September 24, 2002
    Publication date: June 19, 2003
    Applicant: Medicure International Inc.
    Inventors: Wasimul Haque, Rajat Sethi
  • Cardioprotective phosphonates and malonates
    Publication number: 20030114678
    Abstract: The present invention provides for pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) and to pyridoxine malonate analogues, such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)malonates), pharmaceutical compositions, and methods for treatment of cardiovascular and related diseases, and diabetes mellitus and related diseases.
    Type: Application
    Filed: October 28, 2002
    Publication date: June 19, 2003
    Applicant: Medicure International Inc.
    Inventor: Wasimul Haque
  • Pyridoxine and pyridoxal analogues: novel uses
    Patent number: 6548519
    Abstract: The invention provides pyridoxal and pyridoxine analogues, pharmaceutical compositions containing pyridoxine and pyridoxal analogues, and methods of administering pharmaceutical compositions containing a therapeutically effective amount of at least one of these analogues. In accordance with the present invention, the pyridoxal and pyridoxine analogues can be used in the treatment of undesired platelet aggregation, and in the treatment of symptoms thereof.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: April 15, 2003
    Assignee: Medicure International Inc.
    Inventor: Wasimul Haque
  • Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
    Patent number: 6417204
    Abstract: The invention provides pyridoxal and pyridoxine analogues, pharmaceutical compositions containing pyridoxine and pyridoxal analogues, and methods of administering pharmaceutical compositions containing a therapeutically effective amount of at least one of these analogues. In accordance with the present invention, the pyridoxal and pyridoxine analogues can be used in the treatment of cardiovascular or related diseases and in the treatment of symptoms thereof.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: July 9, 2002
    Assignee: Medicure International Inc.
    Inventor: Wasimul Haque