Abstract: Disclosed is a contact lens having a back surface to be placed on a cornea. The back surface includes a generally circular central zone whose radius of curvature gradually decrease from its center toward its periphery, and an peripheral zone disposed around the central zone.

Abstract: A method for adhering and proliferating cell, which comprises the steps of inoculating, culturing and then killing fibroblast derived from a mammal, is provided. A culture vessel manufactured according to the steps of the method which can provide improved adhesion to cell and enhanced cell-proliferation is also provided.

Abstract: An ocular lens material comprising a siloxane-containing polymer obtained by polymerizing a monomer mixture containing (A) a siloxane macromonomer having at least two active unsaturated groups and a number average molecular weight of 2,000 to 100,000; and (B) a vinyl ester of lower fatty acid as essential components. An ocular lens material comprising a polymer obtained by saponification of the siloxane-containing polymer. Processes for producing the ocular lens materials. The ocular lens materials are excellent not only in lipid-stain resistance, wettability and oxygen permeability, but also in flexibility, particularly, shape recovery at the same time.

Abstract: A contact lens wherein a dioptric power P is held within a range of −10-0 diopters, a back junction is located outward of a front junction in a diametric direction orthogonal to a center axis of the lens, a central lens thickness TC measures 0.03-0.50 mm along the center axis, a front junction lens thickness TFJ measures 0.05 mm or more, and a back-junction lens thickness TBJ is determined depending upon said dioptric power P so as to satisfy a following expression: &Sgr;(Ai·10−i·Pi)≦TBJ/TFJ≦&Sgr;(Bi·10−i·Pi) where, A0=+1.2382 A1=−0.1741 A2=−1.4711 A3=−0.9355 B0=+1.4699 B1=−0.2523 B2=−1.9897 B3=−1.2603.

Abstract: A method of designing an ophthalmic lens, including: determining specifications of a temporary lens to provide an optical power required by a wearer; applying the temporary lens to a prescribed schematic eye, and effecting emmetropization of an optical system including the temporary lens and schematic eye; obtaining an optical characteristic of the optical system at a position of an optical axis of the temporary lens which is offset from an optical axis of the schematic eye by an offset amount; obtaining successively optical characteristics corresponding to different configurations of the temporary lens with the axes of the temporary lens and schematic eye offset by the offset amount; selecting optimum one of the different configurations of the temporary lens which gives optimum one of the successively obtained optical characteristics; and determining specifications of an intended ophthalmic lens as a final product, based on the selected optimum configuration of the temporary lens.

Abstract: An ocular lens material comprising a siloxane-containing polymer obtained by polymerizing a monomer mixture containing (A) a siloxane macromonomer having at least two active unsaturated groups and a number average molecular weight of 2,000 to 100,000; and (B) a vinyl ester of lower fatty acid as essential components. An ocular lens material comprising a polymer obtained by saponification of the siloxane-containing polymer. Processes for producing the ocular lens materials. The ocular lens materials are excellent not only in lipid-stain resistance, wettability and oxygen permeability, but also in flexibility, particularly, shape recovery at the same time.

Abstract: A method of disinfecting a contact lens including the steps of: preparing a disinfecting liquid which contains at least one suitably selected metal phthalocyanine compound and hydrogen peroxide, the at least one metal phthalocyanine compound being dispersed or dissolved in an aqueous medium; immersing the contact lens in the disinfecting liquid; and irradiating, with a light, the disinfecting liquid in which the contact lens is immersed.

Abstract: An ocular lens material comprising a copolymer prepared by polymerization with heating of a monomer mixture and/or with irradiating a monomer mixture with ultraviolet ray by means of a molding method, the monomer mixture containing a polysiloxane macromonomer A, a Si-containing alkyl methacrylate B, a hydrophilic monomer C comprising NVP as C-1 and another hydrophilic monomer C-2, another monomer D and a crosslinkable monomer E comprising a crosslinkable monomer E-1 containing at least one group selected from acryloyl group, vinyl group and allyl group, and methacryloyl group, and a crosslinkable monomer E-2 containing at least two methacryloyl groups as main components, wherein (A+B)/C (weight ratio) is 30/70 to 70/30, A/B is 25/75 to 75/25, C-1/C-2 is 50/50 to 100/0, the amount of D is 0 to 20% by weight in the monomer mixture, which has high oxygen permeability, high mechanical strength, excellent surface wettability and low surface frictional property.

Abstract: A method of marking an ophthalmic lens, including a step of irradiating the ophthalmic lens formed of a resin material with a laser radiation of a femtosecond pulse width, such that the laser radiation is condensed at each of predetermined at least one spot within the ophthalmic lens, to form a whitened portion at the each of the predetermined at least one spot, for thereby providing the ophthalmic lens with a marking.

Abstract: A water-absorptive contact lens whose water content is in a range from 10% to 60% and which is formed of a polymeric material obtained by copolymerization of a polymerizable monomer composition that includes: (A) 20 to 70 wt. % of alkoxypolyethylene glycol (meth)acrylate having at least three ethylene glycol units, and (B) 30 to 80 wt. % of a silicon-containing macromonomer.

Abstract: A highly water-absorptive ophthalmic lens which is formed of a macromolecular material including vinyl alcohol unit as a major component, wherein the improvement comprises: the macromolecular material being formed by saponifying a copolymer obtained by copolymerization of a polymerizable monomer composition which consists of vinyl acetate and diethylene glycol divinyl ether; the ophthalmic lens having a water content in a range from 73% to 84%; and the ophthalmic lens having a ratio of a dimensional change of less than ±2% and is free from whitening after (A) the ophthalmic lens has been subjected to three cycles of a freezing-thawing operation wherein the ophthalmic lens formed of the macromolecular material is left at a temperature of not higher than −10° C. for not less than twelve hours, and is subsequently left at a temperature in a range from 15° C. to 30° C. for not less than six hours, and/or (B) the ophthalmic lens has been kept at a temperature in a range from 1° C.

Abstract: Disclosed is a contact lens including an optical zone having a substantially circular shape; an peripheral zone having an annular shape and located around the optical zone; and an intermediate zone having an annular shape and located between the optical and peripheral zones. The intermediate zone including a convex portion formed in at least one radial position of a back surface thereof so as to extend in a circumferential direction thereof with an outwardly curved surface as seen in a diametrical cross-section of the lens.

Abstract: A highly water-absorptive ophthalmic lens which is formed of a macromolecular material including vinyl alcohol unit as a major component and whose water content is in a range of 50-90%, wherein: the macromolecular material is a cross-linked vinyl alcohol-allyl alcohol/halogenated-alkyl ethylene copolymer which includes allyl alcohol unit and/or halogenated-alkyl ethylene unit, together with the vinyl alcohol unit; and the ophthalmic lens has a ratio of a dimensional change of less than ±2% and being free from whitening after (A) the ophthalmic lens has been subjected to three cycles of a freezing-thawing operation wherein the ophthalmic lens formed of the macromolecular material is left at a temperature of not higher than −10° C. for not less than twelve hours, and is subsequently left at a temperature in a range from 15° C. to 30° C. for not less than six hours, and/or (B) the ophthalmic lens has been kept at a temperature in a range from 1° C. to 9° C. for three months.

Abstract: A method of designing an ophthalmic lens, including: determining specifications of a temporary lens to provide an optical power required by a wearer; applying the temporary lens to a prescribed schematic eye, and effecting emmetropization of an optical system including the temporary lens and schematic eye; obtaining an optical characteristic of the optical system at a position of an optical axis of the temporary lens which is offset from an optical axis of the schematic eye by an offset amount; obtaining successively optical characteristics corresponding to different configurations of the temporary lens with the axes of the temporary lens and schematic eye offset by the offset amount; selecting optimum one of the different configurations of the temporary lens which gives optimum one of the successively obtained optical characteristics; and determining specifications of an intended ophthalmic lens as a final product, based on the selected optimum configuration of the temporary lens.

Abstract: An ocular lens material comprising a copolymer prepared by polymerization with heating of a monomer mixture and/or with irradiating a monomer mixture with ultraviolet ray by means of a molding method, the monomer mixture containing a polysiloxane macromonomer A, a Si-containing alkyl methacrylate B, a hydrophilic monomer C comprising NVP as C-1 and another hydrophilic monomer C-2, another monomer D and a crosslinkable monomer E comprising a crosslinkable monomer E-1 containing at least one group selected from acryloyl group, vinyl group and allyl group, and methacryloyl group, and a crosslinkable monomer E-2 containing at least two methacryloyl groups as main components, wherein (A+B)/C (weight ratio) is 30/70 to 70/30, A/B is 25/75 to 75/25, C-1/C-2 is 50/50 to 100/0, the amount of D is 0 to 20% by weight in the monomer mixture, which has high oxygen permeability, high mechanical strength, excellent surface wettability and low surface frictional property.

Abstract: A process for producing an ocular lens having a highly hydrophilic lens surface, comprising a polymer obtained by polymerizing a monomer mixture containing a hydrophilic monomer, which comprises:

Abstract: A method of modifying a surface of an ophthalmic lens, includes the steps of: generating plasma at an atmospheric pressure between electrodes of a plasma generating device; and blowing the plasma from the plasma generating device by introducing a gas between the electrodes. The ophthalmic lens, which is located outside the plasma generating device, is irradiated with the plasma blown out from the plasma generating device to modify the surface of the ophthalmic lens to form a final ophthalmic lens product.

Abstract: An ophthalmic solution or contact lens solution comprising at least one germicidal/preservative component. The ophthalmic solution further comprises at least one selected amino-acid-based component, 0-0.2 wt. % of sodium chloride, and 0-0.5 wt. % of phosphate. The contact lens solution further comprises at least one selected acidic component and 0-0.2 wt. % of sodium chloride. Alternatively, the contact lens solution further comprises at least one selected amino-acid-based component, at least one selected acidic compound, and 0-0.2 wt. % of sodium chloride.

Abstract: Disclosed is a contact lens having a refractive power ranging from −15.0 to +15.0 diopters in an optical zone thereof, wherein a back optical zone is a conical surface having a conic coefficient ranting from −0.04 to −0.49, and a front optical zone is a conical surface having a conic coefficient ranging from −0.02 to −0.50. The contact lens exhibits optical characteristics required in consideration of an optical system of an eye when being positioned at a position of rest during wear in which an optical axis of the optical zone is decentered with respect to an optical axis of the eye.

Abstract: An ocular lens having a desired shape without having a deformation induced by its process, and having a uniform coat layer on its surface, is proceeded by single mold polymerization. The ocular lens is produced by a process comprising a step of irradiating at least one part of the molding surface for the ocular lens of the mold with an excimer light, a step of coating a compound fixable to the ocular lens surface by an interaction with a polymerizable component in the ocular lens material, or its solution on the mold surface after irradiating with an excimer light, a step of filling the ocular lens material into the mold after coating, and polymerizing, a step of releasing a polymer obtained by the polymerization from the mold, and obtaining an ocular lens stock material having above-mentioned component fixed on its surface, and a step extracting unfixed unreacted components from obtained ocular lens stock material.