Patents Assigned to Menicon Co., Ltd.
  • Patent number: 6357876
    Abstract: A multifocal ocular lens having a vision correction area including at least one distant vision correction region having a first optical power value for distant vision correction and at least one near vision correction region having a second optical power value for near vision correction, wherein the vision correction area further includes a central intermediate-distance vision correction region which has a third optical power value for intermediate vision correction between the first and second optical power values and which is located in a central portion of the vision correction area such that the distant and near vision correction regions are located radially outwardly of the central intermediate-distance vision correction region.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: March 19, 2002
    Assignee: Menicon Co., Ltd.
    Inventors: Hiroyuki Oyama, Hideaki Kondou, Kazuya Miyamura
  • Publication number: 20020031828
    Abstract: A method for adhering and proliferating cell, which comprises the steps of inoculating, culturing and then killing fibroblast derived from a mammal, is provided. A culture vessel manufactured according to the steps of the method which can provide improved adhesion to cell and enhanced cell-proliferation is also provided.
    Type: Application
    Filed: November 20, 2001
    Publication date: March 14, 2002
    Applicant: MENICON CO., LTD.
    Inventors: Nobutaka Yamamoto, Akihisa Sugiyama, Satoshi Kawaminami
  • Patent number: 6355190
    Abstract: A method of molding an ophthalmic lens product by using a mold assembly which has a mold cavity, the lens product having a configuration corresponding to that of an ophthalmic lens or a precursor of the ophthalmic lens and being obtained by polymerizing a liquid monomer composition in the mold cavity to provide a polymer product which gives the lens product, the method comprising the steps of: preparing the mold assembly having a monomer storage space for storing the liquid monomer composition, which storage space is held in fluid communication with the mold cavity; filling the mold cavity of the mold assembly with the liquid monomer composition while the liquid monomer composition is accommodated in the monomer storage space; and polymerizing the liquid monomer composition at a temperature of 10-80° C. while a pressure higher than the atmospheric pressure is applied directly to a liquid surface of a mass of the liquid monomer composition accommodated in the monomer storage space.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: March 12, 2002
    Assignee: Menicon Co., Ltd.
    Inventors: Tatsuya Ojio, Kazuharu Niwa, Keiji Yamashita, Akihiro Yasuda
  • Patent number: 6346594
    Abstract: An ocular lens material comprising a silicone compound having a zwitterionic group (I) represented by the formula (I): wherein R1 is H or an alkyl, R2 is an aliphatic hydrocarbon or an aromatic hydrocarbon, A1 is O, S, NH or direct bond, A2 is POO− or SOO−, A3 is O, S, NH or ═O, in which when A2 is SOO−, A1 and A3 are not S, and when A3 is ═O, R2 is absent, each of p and q is 1 to 20; a zwitterionic group (II) represented by the formula (II): wherein R3 is H or an alkyl, A4 is O, S, NH or direct bond, each of r, s and t is 1 to 20; or a zwitterionic group (III) represented by the formula (III): wherein R4 is H or an alkyl, each of A5 and A6 is O, S, NH or direct bond, in which A5 and A6 are not direct bonds at the same time, u is 1 to 20, and a process for producing the same. The ocular lens material shows excellent transparency, oxygen permeability, deposit resistance and wettability to tears at the same time.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: February 12, 2002
    Assignee: Menicon Co., Ltd.
    Inventors: Tsuyoshi Watanabe, Masaki Baba
  • Publication number: 20020016270
    Abstract: A solution for contact lenses which comprises an amino acid type cationic surfactant and at least one nonionic surfactant.
    Type: Application
    Filed: June 13, 2001
    Publication date: February 7, 2002
    Applicant: Menicon Co., Ltd.
    Inventors: Akira Tsuzuki, Sadayasu Tanikawa
  • Publication number: 20010050749
    Abstract: A process for preparing an ocular lens material having hydrophilic surface, characterized by comprising the steps of (1) irradiating the surface of an ocular lens material with high-frequency plasma or excimer ultarviolet-ray; (2) contacting the surface of the ocular lens material, which is treated in accordance with the step (1), with a hydrophilic monomer-mixture solution containing at least one zwitterionic group-containing compoud; and (3) irradiating the surface of the ocular lens material, which is in the state of contacting with the hydrophilic monomer-mixture solution in the step (2), with ultraviolet-ray having a wavelength of 250 to 500 nm and then, graft polymerizing the zwitterionic group-containing compound to the surface of the ocular lens material and then, forming a surface layer; and an ocular lens material having hydrophilic surface prepared by the process.
    Type: Application
    Filed: March 19, 2001
    Publication date: December 13, 2001
    Applicant: Menicon Co., Ltd.
    Inventor: Tsuyoshi Watanabe
  • Patent number: 6329445
    Abstract: An ocular lens material comprising a polymer prepared by polymerizing a component containing a benzotriazole compound (A) represented by the formula (I): wherein X is hydrogen, a halogen, an alkyl having 1 to 3 carbons or an alkoxy having 1 to 3 carbons, R1 is an alkylene having 2 to 10 carbons, R2 is hydrogen, methyl or a halogenated methyl, R3 is hydrogen, an alkyl or an aryl, and each of R4 and R5 is independently an alkyl having 1 to 8 carbons. The material shows excellent ultraviolet-ray absorbing power and oxidation inhibiting power at the same time.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: December 11, 2001
    Assignee: Menicon Co., LTD
    Inventors: Akiko Okumura, Kazuhiko Nakada, Akinori Okumura
  • Patent number: 6326448
    Abstract: A soft intraocular lens material which consists essentially of a polymer obtained by polymerizing polymerizable components containing a hydrophilic monomer, and which has a water absorptivity of from 1.5 to 4.5 wt %.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: December 4, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Tatsuya Ojio, Kazuharu Niwa, Tohru Kawaguchi
  • Patent number: 6320008
    Abstract: A polymeric colorant represented by the following formula: A1—N═N—A2—O—(CH2)n-X wherein, A1 represents an aryl group which may have a substituent group, A2 represents an arylene group which may have a substituent group, X represents one of an acryloyloxy group, a methacryloyloxy group, a vinylphenyl group, a vinylphenyloxy group, and a vinylphenylalkyloxy group whose alkyl portion has 1-5 carbon atoms, and n is an integer of 1-5, and a colored material for an ocular lens which uses to the polymeric colorant is also disclosed.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: November 20, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Akira Tsuzuki, Kazuharu Niwa, Tatsuya Ojio
  • Patent number: 6315929
    Abstract: A mold assembly for forming an ophthalmic lens, the mold assembly comprising a first mold and a second mold which cooperate with each other to define therebetween a mold cavity having a profile following that of the ophthalmic lens, wherein the improvement comprises: at least one of the first and second molds being a coated mold consisting of a body portion including a backing surface having rigidity and mechanical strength enough to withstand a molding operation for forming the ophthalmic lens in the mold cavity, and a thermoplastic film retained on the body portion such that the thermoplastic film covers the backing surface of the body portion, the thermoplastic film having a molding surface which partially defines the mold cavity and which gives a corresponding one of opposite surfaces of the ophthalmic lens.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: November 13, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Kenichi Ishihara, Motonobu Togo
  • Publication number: 20010031318
    Abstract: A process for preparing an ultraviolet-ray-absorbable and low water-containing soft contact lens, characterized by immersing a low water-containing soft contact lens in a solution (I) prepared by dissolving an ultraviolet-ray absorbing agent in a swelling solution, permeating the ultraviolet-ray absorbing agent to the inside of a swollen low water-containing soft contact lens, and then removing the swelling solution used for swelling of the low water-containing soft contact lens. According to the process, the ultraviolet-ray absorbing agent can be physically captured to the inside of the contact lens to impart ultraviolet-ray absorbability to the contact lens without elution of ultraviolet-ray absorbing agent and the ultraviolet-ray-absorbable and low water-containing soft contact lens can be prepared without inhibition of polymerization.
    Type: Application
    Filed: March 6, 2001
    Publication date: October 18, 2001
    Applicant: MENICON CO., LTD.
    Inventors: Misako Nishibayashi, Eri Ito, Kazuhiko Nakada
  • Publication number: 20010021759
    Abstract: A polymeric colorant represented by the following formula:
    Type: Application
    Filed: April 17, 2001
    Publication date: September 13, 2001
    Applicant: Menicon Co., Ltd.
    Inventors: Akira Tsuzuki, Kazuharu Niwa, Tatsuya Ojio
  • Publication number: 20010016190
    Abstract: It is an object of the present invention to provide a water-soluble antibacterial polymer having an excellent antibacterial property and stability, and a liquid formulation comprising it for contact lenses, which is suitably used for disinfection or preservation of contact lenses.
    Type: Application
    Filed: January 30, 2001
    Publication date: August 23, 2001
    Applicant: MENICON CO., LTD.
    Inventors: Kazuhiko Nakada, Sadanori Oono
  • Patent number: 6277940
    Abstract: There is provided a material for a soft intraocular lens, which has excellent transparency and flexibility, can be inserted from a small incision and has an high refractive index independent on a water content. The material comprises (A) 5-25 % by weight of acrylate containing an aromatic ring, (B) 50-90 % by weight of 2-hydroxyethyl (meth)acrylate, and (C) 5-45 % by weight of a (meth)acrylate monomer having the coefficient of water absorption of the homopolymer thereof of not more than 30 % by weight, except for (A) acrylate containing an aromatic ring and (B) 2-hydroxyethyl (meth)acrylate.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: August 21, 2001
    Assignee: Menicon Co. Ltd
    Inventors: Kazuharu Niwa, Tatsuya Ojio, Toru Kawaguchi
  • Patent number: 6276920
    Abstract: Mold assembly for forming a lens blank for an ophthalmic lens, wherein upper and lower tapered inner surfaces of intermediate sleeve are adapted to be held in press-fitting engagement with respective outer surfaces of upper and lower molds, to effect fluid-tight connection of the upper and lower molds with the intermediate sleeve, with the upper mold being held in abutting contact with a shoulder of the intermediate sleeve, and with stopper surfaces of the intermediate and lower molds being held in abutting contact with each other to determine a relative axial position therebetween, such that a mold cavity to be filled with a liquid monomer composition is defined by the upper and lower molds and the intermediate sleeve, while a liquid reservoir for storing an excess amount of the monomer composition which has been discharged from the mold cavity is defined by the upper mold and the intermediate mold.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: August 21, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Atsuhiro Doke, Seiichi Ichikawa
  • Patent number: 6265499
    Abstract: A process for producing a shaped product, which comprises polymerizing a mixture comprising a radical scavenger, a polymerization initiator and a radical polymerizable monomer to obtain a partially polymerized mixture having the conversion of the monomer into the polymer of from 5 to 90 wt %, filling the partially polymerized mixture in a predetermined cavity and then applying polymerization energy to complete polymerization.
    Type: Grant
    Filed: November 27, 1998
    Date of Patent: July 24, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Haruko Nagino, Ichiro Ando
  • Publication number: 20010008314
    Abstract: A mold assembly for forming an ophthalmic lens, or a lens blank from which one ophthalmic lens is produced by effecting a cutting operation on at least one of a front surface and a back surface of the lens blank, the mold assembly consisting of a first mold having a molding surface and a second mold having a molding surface, which first and second molds are assembled together so as to define therebetween a mold cavity having a profile corresponding to that of the ophthalmic lens or the lens blank, the mold cavity being filled with a polymeric material which is polymerized to form the ophthalmic lens or the lens blank, wherein at least one of the first and second molds is a layered mold which is constituted by a composite sheet comprising a metal sheet layer and at least one resin layer which are laminated on each other, the at least one resin layer of the composite sheet providing the molding surface of the layered mold which partially defines the mold cavity.
    Type: Application
    Filed: January 3, 2001
    Publication date: July 19, 2001
    Applicant: Menicon Co., Ltd.
    Inventors: Yuki Tanaka, Chikai Kosaka
  • Patent number: 6260966
    Abstract: A multifocal ocular lens having a vision correction area which includes a central and outer vision correction region, an intermediate region located between the central and outer regions, and an intermediate-distance vision correction region located radially outwardly of and adjacent to the outer region, and which has an optical axis with which centers of these regions are aligned, the central and outer vision correction regions having respective different first and second optical power values, wherein the optical power of the intermediate region located between the central and outer regions is represented by a combination of two different quadratic curves connected to each other at a point of inflection which corresponds to a desired third optical power between the first and second values, and wherein the intermediate-distance vision correction region located radially outwardly of the outer region includes radially inner and outer varying-power zones, the optical power in the radially inner varying-power zon
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: July 17, 2001
    Assignee: Menicon Co. Ltd.
    Inventors: Tadashi Sawano, Hiroyuki Ohyama, Kazuya Miyamura, Yuuzi Gotou, Hideaki Kondou
  • Patent number: 6258299
    Abstract: A device comprises a lower die 6 composed of a lower die base portion and a lower die columnar portion of which tip surface is formed with a lower die molding surface corresponding to one surface of an ocular lens material; an upper die 8 composed of an upper die base portion that is fitted into an upper portion of a hollow hole of the cylindrical main body for parting the hollow hole into two, forming an intermediate chamber 18 between itself and the lower die base portion into which the monomer composition is filled, and forming an exterior accumulating chamber 20 on a side of an upper aperture of the hollow hole into which the monomer composition is accumulated, and an upper die columnar portion of which tip surface is formed with an upper die molding surface corresponding to another surface of the ocular lens material, wherein a molding cavity 22 having a communicating portion 24 is formed between the upper die molding surface and the lower die molding surface; and not less than three piercing holes 16 pr
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: July 10, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Keiji Yamashita, Tatsuya Ojio, Tohru Kawaguchi
  • Patent number: 6257547
    Abstract: Lens mold assembly including a first and a second mold cooperating with each other to define a mold cavity for molding an ophthalmic lens with the first and second molds being held in line contact with each other at a radial position, wherein at least one of the two molds consists of a central molding portion located radially inwardly of the radial position, and an outer rim portion located radially outwardly of the radial position, the central molding portion cooperating with the other mold to define the mold cavity, the above-indicated at least one mold having a mold surface which is opposed to a mold surface of the other mold when the two molds are assembled together, the mold surface of the at least one mold consisting of a central lens-forming region in the central molding portion, and an outer peripheral non lens-forming region in the outer rim portion, at least a part of the lens-forming region adjacent to the radial position providing a concave portion, while at least a part of the outer peripheral no
    Type: Grant
    Filed: June 1, 1999
    Date of Patent: July 10, 2001
    Assignee: Menicon Co., Ltd.
    Inventors: Motonobu Togo, Kenichi Ishihara