Abstract: A cross-laminated timber (CLT) and cold formed steel (CFS) connector and system is provided. The CLT and CFS connector comprises a track, at least one fastener, and at least one spring. The track is configured to connect to at least one CFS stud. The at least one fastener includes a head and shaft. The at least one fastener is configured to connect the track to a CLT panel. The at least one spring is configured to receive the shaft of the fastener and compress between the head of the fastener and the track. Methods of installing the CLT and CFS connector and system are also provided.

Abstract: In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two-dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.

Abstract: A shear wall assembly is provided. The assembly includes a first anchor, a second anchor, a third anchor, a first bolt, a second bolt, a seismic fuse, and a rod. Each anchor includes a hollow tubular body including a first open end, a second open end, an interior including female threads, and an exterior including male threads. Each bolt includes a head and a shank. The shank includes male threads. The shank extends through an open end of an anchor. The male threads of the bolt engage with the female threads of the anchor. The seismic fuse is configured to receive the heads of the bolts and includes a hole. The rod includes an end with male threads. The rod extends through the hole of the seismic fuse into the open end of an anchor. The male threads of the rod engage with the female threads an anchor.

Abstract: Compounds, such as cathinone derivatives, and pharmaceutical formulations that include the compounds. The compounds may have a first selectivity for a first receptor subtype that is at least 10 times greater than a second selectivity for a second receptor subtype from the same class of receptors. Methods of treating patients, which may include administering to a patient a pharmaceutical formulation that includes a compound, such as a cathinone derivative.

Abstract: A differential density absorbent towel paper product comprising at least one absorbent towel paper web is disclosed. The absorbent towel paper web has: (a) from about 20% to about 90% by weight of the dry fiber basis of the absorbent towel paper web of a refined soft wood pulp fiber mixture, (b) pulp fibers selected from the group consisting of hard wood fibers, non-wood fibers, recycled fibers, synthetic polymer fibers, bleached eucalyptus kraft fibers, and combinations thereof and, (c) not more than about 10% by weight moisture. The refined soft wood pulp fiber mixture has: i) from about 18.5% to about 88.5% by weight of soft wood pulp fiber; ii) from about 0.25% to about 5.0% by of cationic strengthening polymer; and, iii) from about 0.05% to about 20% by weight of cellulose nano-filaments.

Abstract: A differential density absorbent towel paper product comprising at least one absorbent towel paper web is disclosed. The absorbent towel paper web has: (a) from about 20% to about 90% by weight of the dry fiber basis of the absorbent towel paper web of a refined soft wood pulp fiber mixture, (b) pulp fibers selected from the group consisting of hard wood fibers, non-wood fibers, recycled fibers, synthetic polymer fibers, bleached eucalyptus kraft fibers, and combinations thereof and, (c) not more than about 10% by weight moisture. The refined soft wood pulp fiber mixture has: i) from about 18.5% to about 88.5% by weight of soft wood pulp fiber; ii) from about 0.25% to about 5.0% by of cationic strengthening polymer; and, iii) from about 0.05% to about 20% by weight of cellulose nano-filaments.

Abstract: A shear wall assembly is provided. The assembly includes a first anchor, a second anchor, a third anchor, a first bolt, a second bolt, a seismic fuse, and a rod. Each anchor includes a hollow tubular body including a first open end, a second open end, an interior including female threads, and an exterior including male threads. Each bolt includes a head and a shank. The shank includes male threads. The shank extends through an open end of an anchor. The male threads of the bolt engage with the female threads of the anchor. The seismic fuse is configured to receive the heads of the bolts and includes a hole. The rod includes an end with male threads. The rod extends through the hole of the seismic fuse into the open end of an anchor. The male threads of the rod engage with the female threads an anchor.

Abstract: A double plate floor panel is provided. The double plate floor panel includes a first panel, a second panel, and a plurality of connectors. The first panel has a first plurality of recesses on a first surface, and the second panel has a second plurality of recesses on a second surface. Each connector of the plurality of connectors inserts into a recess of the first plurality of recess and a recess of the second plurality of recesses. The connectors are sandwiched between the first surface of the first panel and the second surface of the second panel. A method of assembling the double plate floor panel is also provided.

Abstract: A differential density paper product comprising at least one paper web is disclosed. The paper product has: (a) from about 20% to about 90% by weight of the dry fiber basis of the paper product of a refined soft wood pulp fiber mixture, (b) pulp fibers selected from the group consisting of hard wood fibers, non-wood fibers, recycled fibers, synthetic polymer fibers, bleached eucalyptus kraft fibers, and combinations thereof; and, (c) not more than about 10% by weight moisture.

Abstract: The present disclosure provides for a paper product. The paper product has: (a) from about 20% to about 90% by weight of the dry fiber basis of the paper product of a refined soft wood pulp fiber mixture, (b) pulp fibers selected from the group consisting of hard wood fibers, non-wood fibers, recycled fibers, synthetic polymer fibers, bleached eucalyptus kraft fibers, and combinations thereof; and, (c) not more than about 10% by weight moisture.

Abstract: A method for producing at least one microneedle containing a vaccine for transdermal delivery of the vaccine to a patient includes preparing microparticles or nanoparticles of encapsulated vaccine by preparing a solution comprising a vaccine antigen and a biocompatible polymer matrix; and spray drying the solution to form the microparticles or nanoparticles. The method includes the further steps of preparing a film composition including at least one pre-polymer solution; preparing a suspension comprising the microparticles or nanoparticles and the film composition; loading the suspension into a 3D printer; printing, via the 3D printer, at least one microneedle made from the suspension; and, converting the pre-polymer solution into a cross-linked biopolymer by exposing the at least one microneedle to UV light. Also disclosed are microneedles containing a vaccine for transdermal delivery.

Abstract: A method of erecting a carton from a blank, including: engaging the blank with a punch head against which the carton is formed, folding side portions of the blank against the punch head to form sides of the carton; folding outer portions of the side portions of the blank away from the punch head and against an external side of the carton; folding end portions of the blank against the punch head to form end portions of the carton; folding outer portions of the end portions of the blank away from the punch head and against an external end of the carton; and securing corner gussets formed between the side and end portions against sides or ends of the carton.

Abstract: An oral dissolving film containing nano- or micro-encapsulated bioactive material and methods of forming the film. The film may be prepared by dispensing a mixture of a film-forming agent, a crosslinking agent, a solution of nano- or micro-encapsulated bioactive material, and a photoinitiator into a plurality of wells in a tray using a 3D printer. The dispensed material is exposed to radiation in order to crosslink the material and form a film.

Abstract: A cross-laminated timber (CLT) and cold formed steel (CFS) connector and system is provided. The CLT and CFS connector comprises a track, at least one fastener, and at least one spring. The track is configured to connect to at least one CFS stud. The at least one fastener includes a head and shaft. The at least one fastener is configured to connect the track to a CLT panel. The at least one spring is configured to receive the shaft of the fastener and compress between the head of the fastener and the track. Methods of installing the CLT and CFS connector and system are also provided.

Abstract: A cross-laminated timber (CLT) and cold formed steel (CFS) connector and system is provided. The CLT and CFS connector comprises a track, at least one fastener, and at least one spring. The track is configured to connect to at least one CFS stud. The at least one fastener includes a head and shaft. The at least one fastener is configured to connect the track to a CLT panel. The at least one spring is configured to receive the shaft of the fastener and compress between the head of the fastener and the track. Methods of installing the CLT and CFS connector and system are also provided.

Abstract: In one aspect, a wall panel is provided that includes a cross laminated timber panel, a first extrusion, and a second extrusion. The cross laminated timber panel includes a top side, a bottom side, a first side, and a second side. The panel also includes a notch in the bottom side and a T-flange on the top side. A wall system is provided comprising a plurality of wall panels. A method of installing the wall panel system is also provided.

Abstract: A process for improving high aspect ratio cellulose filament blends comprising the steps of: a) providing a blend of cellulose nano-filaments or blend of cellulose micro-filaments; b) diluting the blend of cellulose nano-filaments or the blend of cellulose micro-filaments to a target consistency; c) fractionating the diluted blend of cellulose nano-filaments or the diluted blend of cellulose micro-filaments from the step c); and, d) collecting the fraction of the diluted blend of cellulose nano-filaments or the diluted blend of cellulose micro-filaments from the step c) having an average length of greater than at least about 25 ?m.

Abstract: A floor to wall connector is provided. The floor to wall connector comprises a wall bracket and a floor bracket. The wall bracket includes a floor receiver. The wall bracket is configured to connect to a wall panel. The floor bracket includes an opening. The floor bracket is configured to connect to a floor panel. The floor receiver of the wall bracket is configured to insert into the opening of the floor bracket thereby connecting the wall panel to the floor panel. A floor and wall system including the floor to wall connector and a method of connecting a wall panel to a floor panel via the floor to wall connector is also provided.