Patents Assigned to Merck Patent Gesellschaft Mit Beschraenkter Haftung
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Patent number: 5164111Abstract: The invention relates to polymerizable liquid-crystal materials and to polymer materials which exhibit liquid-crystal phases and which contain, attached directly or via a spacer, mesogenic groups in which at least one transversely polarizing structural element of the formulae I to X, defined in claim 1, is present.Type: GrantFiled: July 13, 1990Date of Patent: November 17, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Dieter Dorsch, Rudolf Eidenschink, Andreas Wachtler, Bernhard Rieger, Heino Finkelmann
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Patent number: 5164114Abstract: Ethyne derivatives of the formula IR.sup.1 --(A.sup.1 --Z.sup.1).sub.m --A.sup.3 --C.tbd.C--A.sup.4 --(Z.sup.2 --A.sup.2).sub.n --R.sup.2 Iwherein R.sup.1, A.sup.1, Z.sup.1, m, A.sup.3, A.sup.4, .sub.2 Z.sup.2 and n have the meaning given in Claim 1 and R.sup.2 is --OCF.sub.3, --OC.sub.2 F.sub.4 H or --OC.sub.2 F.sub.5, are suitable as components of liquid crystal phases.Type: GrantFiled: November 25, 1988Date of Patent: November 17, 1992Assignee: Merck Patent Gesellschaft Mit Beschraenkter HaftungInventors: Hans A. Kurmeier, Volker Reiffenrath, Eike Poetsch, Joachim Krause, Georg Weber
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Patent number: 5162155Abstract: The invention relates to silane derivatives of the formula I ##STR1## their preparation by hydrosilylation of corresponding (meth)acrylamides and their use as silylating agents.Type: GrantFiled: September 11, 1990Date of Patent: November 10, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Heinz Berndt, Hartwig Hocker, Rolf Kuropka, Joachim Kinkel
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Patent number: 5156678Abstract: Effect pigments based on interference pigments coated with phthalocyanine or metal phthalocyanine dyes, characterized in that the dyes are applied to the pigments as a strongly adhering film without the aid of binders or other auxiliary materials, are outstandingly suitable for use in formulations such as paints, dyes, plastics and cosmetics.Type: GrantFiled: March 25, 1991Date of Patent: October 20, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventor: Ralf Glausch
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Patent number: 5149853Abstract: In a process for the production of thin films and epitaxial layers by gas-phase deposition, intramolecularly stabilized organometallic compounds are employed as a source of metal.Type: GrantFiled: November 8, 1991Date of Patent: September 22, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Dietrich Erdmann, Max E. Van Ghemen, Ludwig Pohl, Herbert Schumann, Uwe Hartmann, Wilfried Wassermann, Meino Heyen, Holger Jurgensen
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Patent number: 5147857Abstract: New glycolic acid derivatives of the formula IX--O--CR.sup.1 R.sup.2 --CO--Y--NR.sup.3 --CHR.sup.4 --CR.sup.5 --CH.sub.2 --CR.sup.6 R.sup.7 --Z Iin which R.sup.1 to R.sup.7, X, Y and Z have the meanings indicated herein, and salts thereof, inhibit the activity of human plasma renin.Type: GrantFiled: March 18, 1991Date of Patent: September 15, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Peter Raddatz, Claus J. Schmitges, Klaus-Otto Minck
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Patent number: 5145250Abstract: A process for the preparation of bone cement for subsequent introduction into the cavity of a bone serving to receive a prosthesis. The components serving for the production of the bone cement are introduced into a cartridge and mixed together during a mixing phase and subsequently undergo a further resting phase. The mixing phase and the resting phase are under automatic program control.Type: GrantFiled: June 15, 1990Date of Patent: September 8, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Heinrich Planck, Christoph Elser, Albrecht Grieben, Werner Ege
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Patent number: 5141511Abstract: The invention relates to a process for the preparation of a resorptive bone ceramic on the basis of tricalcium phosphate which can be used as a bone replacement material. In the process, natural bone material, freed from the soft tissues, is used as the starting material. The remaining organic substances are removed from this starting material by pyrolysis. The remaining bone material, which consists virtually completely of hydroxyapatite, is subsequently treated with a phosphate carrier and then subjected to a sintering step.Type: GrantFiled: February 7, 1990Date of Patent: August 25, 1992Assignee: Merck Patent Gesellschaft mit Beschraenkter HaftungInventor: Gerd Bauer
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Patent number: 5137885Abstract: Thiadiazinones of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meaning given in claim 1, show positively inotropic and vasodilating action and are suitable for combating cardiovascular diseases.Type: GrantFiled: December 20, 1991Date of Patent: August 11, 1992Assignee: Merck Patent Gesellschaft Mit Beschraenkter HaftungInventors: Rochus Jonas, Ingeborg Lues, Norbert Beier, Michael Klockow, Klaus-Otto Minck
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Patent number: 5133756Abstract: According to a process for producing a bone replacement material, natural bones are used as raw material, the soft parts of the bones are removed, as well as any residual organic substances, and the remaining osseous substance is finally sintered at temperatures between 1100 degrees and 1500 degrees Celcius. In order to simplify such a process and to ensure a more gentle processing of the inorganic bone matrix, the bones are dried at an increased temperature, maximum 550 degrees Celcius, with a reduced air supply or in a reducing atmosphere, then the temperature of the bones is increased during the following step up to 750 degrees to 800 degrees Celcius, with an increased air supply, and finally the bones are sintered.Type: GrantFiled: February 20, 1990Date of Patent: July 28, 1992Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Gerd Bauer, Freimut Vizethum
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Patent number: 4952696Abstract: The invention relates to a process for resolving the enantiomers of trans-3-hydroxy-3,4-dihydro-2,2-dimethyl-4-(2-oxo-1,2-dihydropyridin-1-yl) -2H -1-benzopyran-6-carbonitrile (I), characterized in that racemic I, together with a small amount of (-)-I [or (+)-I], is dissolved in an inert solvent or solvent mixture, the solution is seeded with (-)-I [or (+)-I], the (-)-I [or (+)-I] which has precipitated is isolated, further racemis I is dissolved in the filtrate, the mixture is seeded with (+)-I [or (-)-I], the (+)-I [or (-)-I] which has precipitated is isolated, and if desired this crystallization cycle is repeated once or several times.Type: GrantFiled: February 14, 1990Date of Patent: August 28, 1990Assignee: Merck Patent Gesellschaft mit Beschraenkter HaftungInventor: Ralf M. Devant
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Patent number: 4903722Abstract: An extraction valve head for a tank for high-purity and/or toxic liquid chemicals has an inlet valve for a filler gas, an outlet valve and a purging valve, which closes a bypass between a gas inlet line and an extraction line. The valves are configured as metal diaphragm valves and are fitted in a common metallic valve housing block. All valve seals of the valves are arranged in close spatial proximity to one another in the valve housing block.Type: GrantFiled: March 30, 1989Date of Patent: February 27, 1990Assignee: Merck Patent Gesellschaft mit Beschraenkter HaftungInventors: Frank Joseph, Holger Jurgensen
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Patent number: 4746649Abstract: New diamino acid derivatives of the formula IX--Z--NH--CH(CH.sub.2 R.sup.1)--CH(NH.sub.2)--CH.sub.2 --CO--E--G--Y IwhereinX is H, R.sup.2 --O--C.sub.n H.sub.2n --CO--, R.sup.2 --C.sub.n H.sub.2n --O--CO--, R.sup.2 --C.sub.n H.sub.2n --CO--, R.sup.2 --SO.sub.2, (R.sup.2 --C.sub.n H.sub.2n)--L(R.sup.2 --C.sub.r H.sub.2r)--C.sub.t H.sub.2t --CO--, H--(NHCH.sub.2 CH.sub.2).sub.n --NH--CH.sub.2 CO-- or 9-fluorenyl--C.sub.n H.sub.2n --O--CO--,Z is 0 to 4 amino acid radicals, bonded to one another in a peptide-like manner, selected from the group consisting of Abu, Ada, Ala, Arg, Dab, Gly, His, Ile, Leu, tert.-Leu, Lys, Met, Nbg, Nle, N-Me-His, N-Me-Phe, Orn, Phe, Pro, Ser, Thr, Tic, Trp, Tyr and Val,R.sup.1 is H, A, cycloalkyl with 3-7 C atoms, Ar or C.sub.p H.sub.2p --W,E is absent or is Ala, Gly, Ile, Leu, tert.-Leu, Met, Ser, Thr or Val,G is absent or is His, Phe, Trp, Tyr or --NH--CH(CH.sub.2 R.sup.1)--CH(NH.sub.2)--CH.sub.2 CO--,Y is --O--C.sub.m H.sub.2m --R.sup.3, --NH--C.sub.m H.sub.2m --R.sup.3, --NH--C.Type: GrantFiled: April 2, 1987Date of Patent: May 24, 1988Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Peter Raddatz, Claus Schmitges
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Patent number: 4741457Abstract: The present invention provides a transport container for very pure liquid chemicals having an inner container or flask made of synthetic resin with an upper sealing flange, the inner container being in an outer container, which has a protective collar, provided with openings, surrounding the sealing flange at a distance. The inner container 1 is made of two skins, the inner skin being made of an inert fluoro-synthetic resin and the outer sheet 10 being made of glass-fiber-reinforced synthetic resin completely enclosing the inner skin. The outer skin 10 is in one piece with a cylindrical mantle 11, the upper section of which forms the protective collar 14.Type: GrantFiled: October 9, 1987Date of Patent: May 3, 1988Assignee: Merck Patent Gesellschaft Mit Beschraenkter HaftungInventors: Frank Joseph, Helmuth Krauss
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Patent number: 4698351Abstract: Tetrahydrocarbazole derivatives of the general formula I ##STR1## in which Thc is a 1,2,3,4-tetrahydro-3-carbazolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, the two radicals Y are each H or together are a C-C bond, one radical Z is Ar and the other radical Z is H, A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- and Ar is a phenyl group which is unsubstituted or substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, or is a 2- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts have effects on the central nervous system.Type: GrantFiled: August 22, 1986Date of Patent: October 6, 1987Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Hans-Heinrich Hausberg, Henning Bottch, Rudolf Gottschlich, Christoph Seyfried, Klaus-Otto Minck
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Patent number: 4617293Abstract: Flavonoid phosphates of aminoglycoside antibiotics are useful sparingly soluble salts, e.g., for achieving a depot effect.Type: GrantFiled: May 23, 1984Date of Patent: October 14, 1986Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Helmut Wahlig, Elvira Dingeldein, Richard Kirchlechner, Dieter Orth, Werner Rogalski
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Patent number: 4496447Abstract: Compounds of the formula ##STR1## wherein A, X, Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4, n and m are defined hereinbelow are effective photoinitiators especially for the photopolymerization of ethylenically unsaturated compounds and for the curing of printing inks.Type: GrantFiled: December 21, 1982Date of Patent: January 29, 1985Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Jurgen Eichler, Claus Herz, Karl-Heinz Neisius, Gregor Wehner
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Patent number: 4489057Abstract: Cosmetic compositions containing dibenzoylmethane compounds of the formula ##STR1## wherein R and R.sup.1 are straight-chain or branched alkyl of 1-8 carbon atoms, n an integer from 0-3 and n' an integer from 1-3, dissolved in the fatty components of said composition have superior sun-protection efficiency.Type: GrantFiled: May 12, 1980Date of Patent: December 18, 1984Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Reiner Welters, Juergen Gehlhaus, Gernot Moeschl
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Patent number: 4382012Abstract: Diketones of the formula ##STR1## wherein R.sub.1 is alkyl, perfluoroalkyl or alkoxy, each of 1-18 carbon atoms; R.sub.2 is alkyl or perfluoroalkyl, each of 1-12 carbon atoms; and X is 1,4-trans-cyclohexylene, 1,4-phenylene or 4,4'-cyclohexylphenyl are liquid crystalline compounds.Type: GrantFiled: July 16, 1981Date of Patent: May 3, 1983Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventors: Rudolf Eidenschink, Ludwig Pohl
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Patent number: D299275Type: GrantFiled: November 26, 1986Date of Patent: January 3, 1989Assignee: Merck Patent Gesellschaft mit beschraenkter HaftungInventor: Wilhelm Ott