Patents Assigned to Merck Patent Gesellschaft Mit Beschraenkter Haftung
  • Patent number: 5164111
    Abstract: The invention relates to polymerizable liquid-crystal materials and to polymer materials which exhibit liquid-crystal phases and which contain, attached directly or via a spacer, mesogenic groups in which at least one transversely polarizing structural element of the formulae I to X, defined in claim 1, is present.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: November 17, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Dieter Dorsch, Rudolf Eidenschink, Andreas Wachtler, Bernhard Rieger, Heino Finkelmann
  • Patent number: 5164114
    Abstract: Ethyne derivatives of the formula IR.sup.1 --(A.sup.1 --Z.sup.1).sub.m --A.sup.3 --C.tbd.C--A.sup.4 --(Z.sup.2 --A.sup.2).sub.n --R.sup.2 Iwherein R.sup.1, A.sup.1, Z.sup.1, m, A.sup.3, A.sup.4, .sub.2 Z.sup.2 and n have the meaning given in Claim 1 and R.sup.2 is --OCF.sub.3, --OC.sub.2 F.sub.4 H or --OC.sub.2 F.sub.5, are suitable as components of liquid crystal phases.
    Type: Grant
    Filed: November 25, 1988
    Date of Patent: November 17, 1992
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventors: Hans A. Kurmeier, Volker Reiffenrath, Eike Poetsch, Joachim Krause, Georg Weber
  • Patent number: 5162155
    Abstract: The invention relates to silane derivatives of the formula I ##STR1## their preparation by hydrosilylation of corresponding (meth)acrylamides and their use as silylating agents.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: November 10, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Heinz Berndt, Hartwig Hocker, Rolf Kuropka, Joachim Kinkel
  • Patent number: 5156678
    Abstract: Effect pigments based on interference pigments coated with phthalocyanine or metal phthalocyanine dyes, characterized in that the dyes are applied to the pigments as a strongly adhering film without the aid of binders or other auxiliary materials, are outstandingly suitable for use in formulations such as paints, dyes, plastics and cosmetics.
    Type: Grant
    Filed: March 25, 1991
    Date of Patent: October 20, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventor: Ralf Glausch
  • Patent number: 5149853
    Abstract: In a process for the production of thin films and epitaxial layers by gas-phase deposition, intramolecularly stabilized organometallic compounds are employed as a source of metal.
    Type: Grant
    Filed: November 8, 1991
    Date of Patent: September 22, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Dietrich Erdmann, Max E. Van Ghemen, Ludwig Pohl, Herbert Schumann, Uwe Hartmann, Wilfried Wassermann, Meino Heyen, Holger Jurgensen
  • Patent number: 5147857
    Abstract: New glycolic acid derivatives of the formula IX--O--CR.sup.1 R.sup.2 --CO--Y--NR.sup.3 --CHR.sup.4 --CR.sup.5 --CH.sub.2 --CR.sup.6 R.sup.7 --Z Iin which R.sup.1 to R.sup.7, X, Y and Z have the meanings indicated herein, and salts thereof, inhibit the activity of human plasma renin.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: September 15, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Peter Raddatz, Claus J. Schmitges, Klaus-Otto Minck
  • Patent number: 5145250
    Abstract: A process for the preparation of bone cement for subsequent introduction into the cavity of a bone serving to receive a prosthesis. The components serving for the production of the bone cement are introduced into a cartridge and mixed together during a mixing phase and subsequently undergo a further resting phase. The mixing phase and the resting phase are under automatic program control.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: September 8, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Heinrich Planck, Christoph Elser, Albrecht Grieben, Werner Ege
  • Patent number: 5141511
    Abstract: The invention relates to a process for the preparation of a resorptive bone ceramic on the basis of tricalcium phosphate which can be used as a bone replacement material. In the process, natural bone material, freed from the soft tissues, is used as the starting material. The remaining organic substances are removed from this starting material by pyrolysis. The remaining bone material, which consists virtually completely of hydroxyapatite, is subsequently treated with a phosphate carrier and then subjected to a sintering step.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: August 25, 1992
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventor: Gerd Bauer
  • Patent number: 5137885
    Abstract: Thiadiazinones of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meaning given in claim 1, show positively inotropic and vasodilating action and are suitable for combating cardiovascular diseases.
    Type: Grant
    Filed: December 20, 1991
    Date of Patent: August 11, 1992
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventors: Rochus Jonas, Ingeborg Lues, Norbert Beier, Michael Klockow, Klaus-Otto Minck
  • Patent number: 5133756
    Abstract: According to a process for producing a bone replacement material, natural bones are used as raw material, the soft parts of the bones are removed, as well as any residual organic substances, and the remaining osseous substance is finally sintered at temperatures between 1100 degrees and 1500 degrees Celcius. In order to simplify such a process and to ensure a more gentle processing of the inorganic bone matrix, the bones are dried at an increased temperature, maximum 550 degrees Celcius, with a reduced air supply or in a reducing atmosphere, then the temperature of the bones is increased during the following step up to 750 degrees to 800 degrees Celcius, with an increased air supply, and finally the bones are sintered.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: July 28, 1992
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Gerd Bauer, Freimut Vizethum
  • Patent number: 4952696
    Abstract: The invention relates to a process for resolving the enantiomers of trans-3-hydroxy-3,4-dihydro-2,2-dimethyl-4-(2-oxo-1,2-dihydropyridin-1-yl) -2H -1-benzopyran-6-carbonitrile (I), characterized in that racemic I, together with a small amount of (-)-I [or (+)-I], is dissolved in an inert solvent or solvent mixture, the solution is seeded with (-)-I [or (+)-I], the (-)-I [or (+)-I] which has precipitated is isolated, further racemis I is dissolved in the filtrate, the mixture is seeded with (+)-I [or (-)-I], the (+)-I [or (-)-I] which has precipitated is isolated, and if desired this crystallization cycle is repeated once or several times.
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: August 28, 1990
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventor: Ralf M. Devant
  • Patent number: 4903722
    Abstract: An extraction valve head for a tank for high-purity and/or toxic liquid chemicals has an inlet valve for a filler gas, an outlet valve and a purging valve, which closes a bypass between a gas inlet line and an extraction line. The valves are configured as metal diaphragm valves and are fitted in a common metallic valve housing block. All valve seals of the valves are arranged in close spatial proximity to one another in the valve housing block.
    Type: Grant
    Filed: March 30, 1989
    Date of Patent: February 27, 1990
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Frank Joseph, Holger Jurgensen
  • Patent number: 4746649
    Abstract: New diamino acid derivatives of the formula IX--Z--NH--CH(CH.sub.2 R.sup.1)--CH(NH.sub.2)--CH.sub.2 --CO--E--G--Y IwhereinX is H, R.sup.2 --O--C.sub.n H.sub.2n --CO--, R.sup.2 --C.sub.n H.sub.2n --O--CO--, R.sup.2 --C.sub.n H.sub.2n --CO--, R.sup.2 --SO.sub.2, (R.sup.2 --C.sub.n H.sub.2n)--L(R.sup.2 --C.sub.r H.sub.2r)--C.sub.t H.sub.2t --CO--, H--(NHCH.sub.2 CH.sub.2).sub.n --NH--CH.sub.2 CO-- or 9-fluorenyl--C.sub.n H.sub.2n --O--CO--,Z is 0 to 4 amino acid radicals, bonded to one another in a peptide-like manner, selected from the group consisting of Abu, Ada, Ala, Arg, Dab, Gly, His, Ile, Leu, tert.-Leu, Lys, Met, Nbg, Nle, N-Me-His, N-Me-Phe, Orn, Phe, Pro, Ser, Thr, Tic, Trp, Tyr and Val,R.sup.1 is H, A, cycloalkyl with 3-7 C atoms, Ar or C.sub.p H.sub.2p --W,E is absent or is Ala, Gly, Ile, Leu, tert.-Leu, Met, Ser, Thr or Val,G is absent or is His, Phe, Trp, Tyr or --NH--CH(CH.sub.2 R.sup.1)--CH(NH.sub.2)--CH.sub.2 CO--,Y is --O--C.sub.m H.sub.2m --R.sup.3, --NH--C.sub.m H.sub.2m --R.sup.3, --NH--C.
    Type: Grant
    Filed: April 2, 1987
    Date of Patent: May 24, 1988
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Peter Raddatz, Claus Schmitges
  • Patent number: 4741457
    Abstract: The present invention provides a transport container for very pure liquid chemicals having an inner container or flask made of synthetic resin with an upper sealing flange, the inner container being in an outer container, which has a protective collar, provided with openings, surrounding the sealing flange at a distance. The inner container 1 is made of two skins, the inner skin being made of an inert fluoro-synthetic resin and the outer sheet 10 being made of glass-fiber-reinforced synthetic resin completely enclosing the inner skin. The outer skin 10 is in one piece with a cylindrical mantle 11, the upper section of which forms the protective collar 14.
    Type: Grant
    Filed: October 9, 1987
    Date of Patent: May 3, 1988
    Assignee: Merck Patent Gesellschaft Mit Beschraenkter Haftung
    Inventors: Frank Joseph, Helmuth Krauss
  • Patent number: 4698351
    Abstract: Tetrahydrocarbazole derivatives of the general formula I ##STR1## in which Thc is a 1,2,3,4-tetrahydro-3-carbazolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, the two radicals Y are each H or together are a C-C bond, one radical Z is Ar and the other radical Z is H, A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 -- and Ar is a phenyl group which is unsubstituted or substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO.sub.2 -alkyl, OH, F, Cl, Br, CF.sub.3 and/or CN or by a methylenedioxy group, or is a 2- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts have effects on the central nervous system.
    Type: Grant
    Filed: August 22, 1986
    Date of Patent: October 6, 1987
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Hans-Heinrich Hausberg, Henning Bottch, Rudolf Gottschlich, Christoph Seyfried, Klaus-Otto Minck
  • Patent number: 4617293
    Abstract: Flavonoid phosphates of aminoglycoside antibiotics are useful sparingly soluble salts, e.g., for achieving a depot effect.
    Type: Grant
    Filed: May 23, 1984
    Date of Patent: October 14, 1986
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Helmut Wahlig, Elvira Dingeldein, Richard Kirchlechner, Dieter Orth, Werner Rogalski
  • Patent number: 4496447
    Abstract: Compounds of the formula ##STR1## wherein A, X, Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4, n and m are defined hereinbelow are effective photoinitiators especially for the photopolymerization of ethylenically unsaturated compounds and for the curing of printing inks.
    Type: Grant
    Filed: December 21, 1982
    Date of Patent: January 29, 1985
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Jurgen Eichler, Claus Herz, Karl-Heinz Neisius, Gregor Wehner
  • Patent number: 4489057
    Abstract: Cosmetic compositions containing dibenzoylmethane compounds of the formula ##STR1## wherein R and R.sup.1 are straight-chain or branched alkyl of 1-8 carbon atoms, n an integer from 0-3 and n' an integer from 1-3, dissolved in the fatty components of said composition have superior sun-protection efficiency.
    Type: Grant
    Filed: May 12, 1980
    Date of Patent: December 18, 1984
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Reiner Welters, Juergen Gehlhaus, Gernot Moeschl
  • Patent number: 4382012
    Abstract: Diketones of the formula ##STR1## wherein R.sub.1 is alkyl, perfluoroalkyl or alkoxy, each of 1-18 carbon atoms; R.sub.2 is alkyl or perfluoroalkyl, each of 1-12 carbon atoms; and X is 1,4-trans-cyclohexylene, 1,4-phenylene or 4,4'-cyclohexylphenyl are liquid crystalline compounds.
    Type: Grant
    Filed: July 16, 1981
    Date of Patent: May 3, 1983
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventors: Rudolf Eidenschink, Ludwig Pohl
  • Patent number: D299275
    Type: Grant
    Filed: November 26, 1986
    Date of Patent: January 3, 1989
    Assignee: Merck Patent Gesellschaft mit beschraenkter Haftung
    Inventor: Wilhelm Ott