Abstract: The present invention is related to magnetic pigments comprising a transparent flaky homogeneously composed substrate having two parallel major surfaces and a coating comprising maghemite, to a process for the production of said pigments as well as to their use.
Type:
Application
Filed:
June 8, 2010
Publication date:
April 19, 2012
Applicant:
Merck Patent Gesellschaft Mit Beschrankter Haftung
Abstract: The invention relates to biomarkers based on gene expression products and methods for determining the efficacy of anti-EGFR antibodies in the treatment of EGFR expressing cancer. The invention is further related to the prediction of sensitivity or resistance of a patient suffering from EGFR expressing cancer to the treatment of said patient with a specific anti-EGFR antibody. The invention is preferably related to the identification of respective biomarkers that allow a better prediction of the clinical outcome of the treatment with anti-EGFR antibodies in patients with KRAS wild-type tumors. In this context, the invention especially relates to anti-EFGR antibody c225/cetuximab (Erbitux®) and its use in patients suffering from colorectal Cancer (CRC).
Type:
Application
Filed:
June 15, 2010
Publication date:
April 19, 2012
Applicant:
Merck Patent Gesellschaft Mit Beschrankter Haftung
Abstract: The present invention relates to shape-memory polymers which are distinguished by the fact that they comprise BiOCl pigments as X-ray contrast agents. Polymers doped in this way are used, in particular, in medical technology products, such as, for example, stiffening pins for the spinal column, tooth root cones, as bone cement and in catheter materials.
Type:
Application
Filed:
May 19, 2010
Publication date:
April 12, 2012
Applicants:
ADOLF PFAFF & KARL-FRIEDRICH REICHENBACH GBR, MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Matthias Lergenmueller, Sabine Schoen, Adolf Pfaff, Karl Friedrich Reichenbach
Abstract: The object of the present invention is a new inkjet printable etching composition comprising an etchant, which is activated by a second component. Thus, a further object is the use of this new composition in a process for the etching of surfaces semiconductor devices or surfaces of solar cell devices.
Type:
Application
Filed:
May 12, 2010
Publication date:
April 12, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Oliver Doll, Edward Plummer, Mark James, Ingo Koehler
Abstract: Novel compounds of the formula (I), in which W, T, R1, R2, R3, R4, R5 and R6 have the meanings indicated in Patent Claim (1), are suitable as antidiabetics.
Type:
Grant
Filed:
September 27, 2007
Date of Patent:
April 10, 2012
Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung
Inventors:
Markus Klein, Rolf Gericke, Norbert Beier, Bertram Cezanne, Christos Tsaklakidis, Werner Mederski
Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?xHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1, 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFWRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.
Type:
Grant
Filed:
October 20, 2010
Date of Patent:
April 3, 2012
Assignee:
Merck Patent Gesellschaft Mit Beschrankter Haftung
Inventors:
Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
Abstract: The invention relates to conjugated polymers that comprise phenanthrene and/or indenofluorene units and are free of amine-containing units, to methods of their preparation, to the use of the polymers in organic electronic (OE) devices, and to OE devices comprising the polymers.
Type:
Application
Filed:
May 4, 2010
Publication date:
March 22, 2012
Applicant:
Merck Patent Gesellschaft Mit Beschrankter Haftung
Inventors:
David Sparrowe, Niels Schulte, Frank Egon Meyer
Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer stabilised) and PSA (polymer sustained alignment) type.
Type:
Application
Filed:
April 19, 2010
Publication date:
March 22, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Andreas Taugerbeck, Alexander Hahn, Achim Goetz
Abstract: The invention relates to specific cinnamic acid ascorbates and to the use thereof as UV filters which bond to the skin, and to a process for the preparation thereof, and to preparations comprising these compounds.
Type:
Application
Filed:
April 12, 2010
Publication date:
March 1, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Abstract: The present invention relates to a process for the production of the largest possible spherical, monodisperse polyvinylpyrrolidone (PVP) seed particles in the micron range by dispersion polymerisation. The particles obtained in this way represent novel starting materials for the production of macroporous polymer particles, which can in turn be employed in preparative and analytical chromatography for protein preparation. They can also be employed as base material for further reactions. The novel process for the polymerisation of N-vinylpyrrolidone, which is inexpensive to carry out, gives particles having optimised quantities, such as monodispersity, sphericity and particle diameter, which can be employed in further reactions and have advantageous, in particular improved, properties for use in chromatographic separation methods.
Type:
Application
Filed:
April 27, 2010
Publication date:
March 1, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Abstract: Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim (1), are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.
Type:
Application
Filed:
April 8, 2010
Publication date:
March 1, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Dieter Dorsch, Margarita Wucherer-Plietker, Thomas J.J. Mueller, Eugen Merkul
Abstract: The invention relates to a means in the form of a test strip and a method for the rapid determination of the content of aldehydes in samples.
Type:
Application
Filed:
April 19, 2010
Publication date:
March 1, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Daniel Rupprecht, Stefanie Beil-Seidler, Berthold Wagner
Abstract: The present invention relates to porous, magnetic silica-gel mouldings having novel properties, by means of which separations of substances from reaction solutions and solid-phase reactions are simplified. In addition, a process for the preparation of these separation materials and possible applications thereof are described.
Type:
Application
Filed:
March 17, 2010
Publication date:
February 23, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Abstract: The invention relates to a birefringent layer having negative optical dispersion, a liquid crystal (LC) medium for its preparation, and the use of the birefringent layer and the LC media in optical, electrooptical, electronic, semiconducting or luminescent components or devices.
Type:
Grant
Filed:
March 4, 2008
Date of Patent:
February 21, 2012
Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung
Inventors:
Owain Llyr Parri, Kevin Adlem, Karl Skjonnemand, David Wilkes
Abstract: The present invention relates to pearlescent pigments based on flake-form substrates which have at least one FeOOH layer and at least one TiO2 layer or at least one TiO2/SiO2/TiO2 layer package, and to the use thereof, inter alia, in paints, coatings, printing inks, powder coatings, plastics and in particular in care and decorative cosmetics.
Type:
Grant
Filed:
December 12, 2007
Date of Patent:
February 14, 2012
Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung
Inventors:
Carsten Handrosch, Marcus Mathias, Nicole Schupp, Meike Willius
Abstract: The present invention relates to dielectrically positive, preferably nematic, media comprising one or more polymerisable compounds, to polymer-stabilised media obtained therefrom, to the use thereof in liquid-crystal displays, and to these displays, in particular PSA-IPS, PSA-FFS and PSA-positive VA displays
Type:
Application
Filed:
February 3, 2010
Publication date:
February 9, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Markus Czanta, Izumi Saito, Christian Schoenefeld, Seung-Eun Lee, Sang-Kyu Lee, Ji-Hong Bae
Abstract: The invention relates to a method for producing onium salts with tetrafluoroborate anion by reacting an onium halide with an oxonium tetrafluoroborate, sulfonium tetrafluoroborate, or triphenylcarbonium tetrafluoroborate.
Type:
Grant
Filed:
November 18, 2005
Date of Patent:
January 24, 2012
Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung
Inventors:
Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Andriy Kucheryna, Helge Willner
Abstract: The present invention relates to curable mixtures for the sealing, encapsulation, bonding or coating of opto-electronic components, such as OLEDs, solar cells, optical sensors and liquid-crystal displays, or for the alignment of liquid crystals.
Type:
Application
Filed:
February 25, 2010
Publication date:
January 12, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Matthias Koehler, Volker Meyer, Edgar Boehm, Michael Junge, Eike Poetsch
Abstract: The present invention relates to thiophene derivatives, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, and to LC media and LC displays comprising same.
Type:
Application
Filed:
February 3, 2010
Publication date:
January 5, 2012
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
Inventors:
Axel Jansen, Detlef Pauluth, Harald Hirschmann, Markus Czanta
Abstract: The invention relates to phosphors having a garnet structure of the formula I (Ya,Gdb,Luc,Sed,Sme,Tbf,Prg,Thh,Iri,Sbj,Bik)3-x(All,Gam)5O12:Cex??(I) where a+b+c+d+e+f+g+h+i+j+k=1 l+m=1 and x=0.005 to 0.1, and to a process for the preparation of these phosphors, and to the use thereof as conversion phosphors for conversion of the blue or near-UV emission from an LED.
Type:
Grant
Filed:
February 13, 2008
Date of Patent:
January 3, 2012
Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung
Inventors:
Holger Winkler, Tim Vosgroene, Thomas Juestel, Stephanie Moeller