Patents Assigned to Merck Patent Gesellschaft mit beschrankter
  • COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS
    Publication number: 20110310462
    Abstract: This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, and to colour electrophoretic displays comprising such particles.
    Type: Application
    Filed: January 29, 2010
    Publication date: December 22, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Louise Diane Farrand, Ashley Nathan Smith, Mark James, Jonathan Henry Wilson, Daniel Walker
  • COMBINATION OF INSULIN WITH TRIAZINE DERIVATIVES AND ITS USE FOR TREATING DIABETES
    Publication number: 20110306543
    Abstract: The invention relates to a composition for use as a medicament comprising insulin in combination with at least one compound of formula (I) wherein the radicals R1 to R6 have the meaning according to claim 1, and/or physiologically acceptable salts thereof. Another object of the invention concerns a pharmaceutical composition comprising as active ingredients effective amounts of insulin and at least one compound of formula (I), together with pharmaceutically tolerable adjuvants, for the prophylactic or therapeutic treatment and/or monitoring of physiological and/or pathological conditions that are associated with insulin resistance. The invention also relates to a pharmaceutical package comprising insulin in a first dosage unit and at least one compound of formula (I) in a second dosage unit.
    Type: Application
    Filed: November 13, 2009
    Publication date: December 15, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Didier Mesangeau, Daniel Cravo, Annick Audet
  • PARTICLES FOR ELECTROPHORETIC DISPLAYS
    Publication number: 20110306742
    Abstract: This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, colour electrophoretic displays comprising such particle, and new water-soluble dyes.
    Type: Application
    Filed: January 29, 2010
    Publication date: December 15, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Louise Diane Farrand, Mark James, Matthias Koch, Ashley Nathan Smith, Jonathan Henry Wilson, Mark John Goulding, Daniel Walker
  • NITRIDOSILICATES CO-DOPED WITH ZIRCONIUM AND HAFNIUM
    Publication number: 20110304261
    Abstract: The invention relates to compounds of the formula (I) Ma2-y(Ca,Sr,Ba)1-x-ySi5-zMezN8:EuxCey (I), where Ma=Li, Na and/or K Me=Hf4+ and/or Zr4+ x=0.0015 to 0.20 and y=0 to 0.15 z<4, and to a process for the preparation of these compounds and to the use as phosphors and conversion phosphors for conversion of the blue or near-UV emission from an LED.
    Type: Application
    Filed: February 1, 2010
    Publication date: December 15, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Holger Winkler, Ralf Petry, Tim Vosgroene, Thomas Juestel, Dominik Uhlich, Danuta Dutczak
  • SURFACE-MODIFIED SILICATE FLUORESCENT SUBSTANCES
    Publication number: 20110304264
    Abstract: The invention relates to surface-modified phosphor particles based on luminescent particles which comprise at least one luminescent compound selected from the group of the silicate phosphors, where at least one coating having a thermal conductivity of <20 W/mK and at least one second coating having a thermal conductivity of >20 W/mK have been applied to the luminescent particles, and to a production process.
    Type: Application
    Filed: November 10, 2009
    Publication date: December 15, 2011
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventor: Holger Winkler
  • COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS
    Publication number: 20110297888
    Abstract: This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, and to colour electrophoretic displays comprising such particles.
    Type: Application
    Filed: January 29, 2010
    Publication date: December 8, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Louise Diane Farrand, Mark John Goulding, Jonathan Henry Wilson, Ashley Nathan Smith, Mark James, Daniel Walker
  • THIOPHENE COMPOUNDS FOR LIQUID-CRYSTALLINE MEDIA
    Publication number: 20110301360
    Abstract: The invention relates to liquid-crystalline compounds of the formula I in which R1, R2, A1, A2, A3, A4, Z1, Z2, Z3, V, a, b and c have the meanings indicated in Claim 1, and to liquid-crystalline media comprising at least one compound of the formula I, and to electro-optical displays containing a liquid-crystalline medium of this type.
    Type: Application
    Filed: February 16, 2010
    Publication date: December 8, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Lars Lietzau, Louise Diane Farrand, Markus Czanta, Harald Hirschmann, Michael Wittek, Izumi Saito, Brigitte Schuler
  • 2-oxo-3-benzylbenzoxazol-2-one derivatives and related compounds as Met kinase inhibitors for the treatment of tumours
    Patent number: 8071593
    Abstract: Described are compounds which inhibit, regulate and/or modulate kinase signal transduction, for example of Met kinase. The compounds are of the formulae A1 to A148 and B1 described herein, including 2-oxobenzoxazol-3-ylmethyl]phenyl}carbamate and 2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]carbamate compounds, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. Also described are compositions containing these compounds. Also described are methods for the treatment of diseases in which the inhibition, regulation and/or modulation of kinase signal transduction plays a role by administering these compounds.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: December 6, 2011
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • Fluorosurfactants
    Patent number: 8067625
    Abstract: The present invention relates to fatty acid esters of polyols or sulfonated fatty acid esters or sulfonated fatty acid amides containing at least one group Y, where Y stands for CF3—(CH2)a—O—, SF5—, CF3—(CH2)a—S—, CF3CF2S—, [CF3—(CH2)a]2N— or [CF3—(CH2)a]NH—, where a stands for an integer selected from the range from 0 to 5, or formula (I), where Rf stands for CF3—(CH2)r—, CF3—(CH2)r—O—, CF3—(CH2)r—S—, CF3CF2—S—, SF5—(CH2)t— or [CF3—(CH2)r]2N—, [CF3—(CH2)r]NH— or (CF3)2N—(CH2)r—, B stands for a single bond, O, NH, NR, CH2, C(O)—O, C(O), S, CH2—O, O—C(O), N—C(O), C(O)—N, O—C(O)—N, N—C(O)—N, O—SO2 or SO2—O, R stands for alkyl having 1 to 4 C atoms, b stands for 0 or 1 and c stands for 0 or 1, q stands for 0 or 1, where at least one radical from b and q stands for 1, and r stands for 0, 1, 2, 3, 4 or 5, to processes for the preparation of these compounds, and to uses of these surface-active compounds.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: November 29, 2011
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Wolfgang Hierse, Nikolai (Mykola) Ignatyev, Martin Seidel, Elvira Montenegro, Peer Kirsch, Andreas Bathe
  • PROCESS OF FORMING INSULATING LAYER BY PARTICLES HAVING LOW ENERGY
    Publication number: 20110284801
    Abstract: The invention relates to a process of preparing functional layers, like protection, encapsulation and alignment layers, on an electronic device by a low energy particle beam deposition process, to functional layers obtainable by said process, and to electronic devices comprising such functional layers.
    Type: Application
    Filed: November 18, 2009
    Publication date: November 24, 2011
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Michael Coelle, Owain Llyr Parri, David Sparrowe, Oleg Yaroshchuk, Eugene Telesh
  • Triazabenzo[E]azulene derivatives for the treatment of tumors
    Patent number: 8063040
    Abstract: Novel triazabenzo[e]azulene derivatives of the formula, (I) in which R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of TGF-beta receptor kinase and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: September 29, 2007
    Date of Patent: November 22, 2011
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Guenter Hoelzemann, Hartmut Greiner, Christiane Amendt
  • NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS
    Publication number: 20110281859
    Abstract: Compounds of the formula I, in which D, X, Y, Z, R and R1 have the meanings indicated in Claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumours.
    Type: Application
    Filed: December 22, 2009
    Publication date: November 17, 2011
    Applicant: Merck Patent Gesellschaft MIT Beschrankter Haftung
    Inventors: Timo Heinrich, Frank Zenke, Mireille Krier, Kai Schiemann
  • DOPED GARNET FLUORESCENT SUBSTANCE HAVING RED SHIFT FOR PC LEDS
    Publication number: 20110279022
    Abstract: The invention relates to phosphors having a garnet structure of the formula I (Ya,Lub,Sec,Tbd,The,Irf,Sbg)3?x (Al5?yMgy/2Siy/2)O12:Cex (I), where +b+c+d+e+f+g+h+i=1×=0.005 to 0.1 and y=0 to 4.0, and to a process for the preparation of these phosphors and to the use as conversion phosphors for conversion of the blue or near-UV emission from an LED.
    Type: Application
    Filed: September 2, 2009
    Publication date: November 17, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Holger Winkler, Thomas Juestel, Julian Plewa
  • [(4-oxo-4H-chromen-3-yl)hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)methyl]phosphonic acid derivatives
    Patent number: 8052963
    Abstract: The present invention relates to compounds of the formula (I), where R1 to R3 each, independently of one another, denote H, hydroxyl or alkoxy having 1 to 8 C atoms, R4 denotes alkyl having 1 to 4 C atoms, H, hydroxyl or alkoxy having 1 to 8 C atoms, R5 denotes H or hydroxyl, and R6 denotes H or alkyl having 1 to 18 C atoms, or salts thereof, but where all R1 to R4 together cannot be equal to H, to compositions, and to the preparation and use thereof.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: November 8, 2011
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Christophe Carola, Herwig Buchholz
  • Novel Polymorphic Forms of 3-(1--6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile Hydrochloride Salt and Processes of Manufacturing Thereof
    Publication number: 20110269767
    Abstract: The present invention relates to 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer.
    Type: Application
    Filed: December 4, 2009
    Publication date: November 3, 2011
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Axel Becker, Clemens Kuehn, Christoph Saal, Oliver Schadt, Dieter Dorsch, Heinz Hermann Bokel, Frank Stieber, Cristina Donini
  • BENZOTHIAZOLONE DERIVATIVES
    Publication number: 20110269756
    Abstract: Compounds of the formula I, in which R1, R2, R3, R3?, R4, R4?, E, E?, E? and E?? have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: December 8, 2009
    Publication date: November 3, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat
  • Fluorosurfactants
    Patent number: 8049022
    Abstract: The present invention relates to fatty acid alkanolamides or polyolamides containing at least one group Y, where Y stands for CF3—(CH2)a—O—, SF5—, CF3—(CH2)a—S—, CF3CF2S—, [CF3—(CH2)a]2N— or [CF3—(CH2)a]NH—, where a stands for an integer selected from the range from 0 to 5, or formula (I), where Rf stands for CF3—(CH2)r—, CF3—(CH2)r—O—, CF3—(CH2)r—S—, CF3CF2—S—, SF5—(CH2)r— or [CF3—(CH2)r]2N—, [CF3—(CH2)r]NH— or (CF3)2N—(CH2)r—, B stands for a single bond, O, NH, NR, CH2, C(O)—O, C(O), S, CH2—O, O—C(O), N—C(O), C(O)—N, O—C(O)—N, N—C(O)—N, O—SO2 or SO2—O, R stands for alkyl having 1 to 4 C atoms, b stands for 0 or 1 and c stands for 0 or 1, q stands for 0 or 1, where at least one radical from b and q stands for 1, and r stands for 0, 1, 2, 3, 4 or 5, to processes for the preparation of these compounds, and to uses of these surface-active compounds.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: November 1, 2011
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Wolfgang Hierse, Nikolai (Mykola) Ignatyev, Martin Seidel, Elvira Montenegro, Peer Kirsch, Andreas Bathe
  • POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS
    Publication number: 20110261311
    Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilised blue phase, and in LC media for LC displays of the PS or PSA (“polymer sustained” or “polymer sustained alignment”) type, and to LC media and LC displays comprising these compounds.
    Type: Application
    Filed: April 26, 2011
    Publication date: October 27, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Axel Jansen, Andreas Taugerbeck, Helmut Haensel, Achim Goetz
  • Liquid-crystalline medium and liquid crystal display
    Patent number: 8043671
    Abstract: Disclosed are a liquid-crystalline medium based on a mixture of dielectrically negative polar compounds of each of formulae I and II and the use thereof in an electro-optical display, particularly in a display with passive matrix addressing, based on a VA, ECB, PALC, FFS or IPS effect, and such displays.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: October 25, 2011
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Masahiro Iijima, Nobuo Kubo
  • PYRIDAZINONE DERIVATIVES
    Publication number: 20110257181
    Abstract: Compounds of the formula (I), in which Y, R1, R2, R3 and R3? have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: November 24, 2009
    Publication date: October 20, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat