Abstract: The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
Type:
Grant
Filed:
September 29, 2020
Date of Patent:
October 3, 2023
Assignee:
Merck Patent GmbH
Inventors:
Heidi Rommelaere, Joost Alexander Kolkman, Michael John Scott Saunders, Ann Union, Yolande Chvatchko, Amanda E. I. Proudfoot, Alain Vicari, Denis Bruniquel, Laurent Chevalet, Olivier Leger
Abstract: The present invention relates to effect pigments which are based on flake-form substrates having a circular form factor of 1.2-2 and are coated with at least one high-refractive-index layer, and to the use thereof, inter alia in paints, coatings, printing inks, plastics and in cosmetic formulations.
Type:
Grant
Filed:
July 6, 2020
Date of Patent:
October 3, 2023
Assignee:
MERCK PATENT GMBH
Inventors:
Gerhard Pfaff, Stephanie Andes, Klaus Ambrosius, Ralf Petry, Michael Roesler, Sabine Schoen
Abstract: The present invention encompasses ATR inhibitor for use in the treatment of coronavirus infections, including COVID-19, alone or in combination with one or more additional therapeutic agents.
Abstract: The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.
Type:
Grant
Filed:
June 20, 2018
Date of Patent:
September 26, 2023
Assignee:
Merck Patent GmbH
Inventors:
Ilona Stengel, Kathy Vinokurov, Frank Voges, Aurélie Ludemann
Abstract: The present invention relates to a composition comprising; components a) b) and d); wherein, component a) is a metal compound having the structure (I), component b) is a spin on high carbon polymer, having a polymer backbone comprising mono-cyclic aromatic hydrocarbon, fused-ring ring hydrocarbon moieties, or mixtures of these, having a wt. % of carbon from about 81 wt. % to about 94 wt. %, which is soluble to at least about 5 wt. % in a spin casting solvent, and wherein at least one, of said mono-cyclic aromatic hydrocarbon or said fused-ring ring hydrocarbon moieties, present in said spin on high carbon polymer, is functionalized with at least one alkynyloxy moiety of structure (VIII), and component d) is a spin casting solvent.
Abstract: The present invention relates to formulations for the preparation of organic electronic devices (OLEDs) which comprise (A) at least one specific ester solvent containing an aromatic group and (B) at least one organic functional material selected from organic conductors, organic semiconductors, organic fluorescent compounds, organic phosphorescent compounds, organic light-absorbent compounds, organic light-sensitive compounds, organic photosensitisation agents and other organic photoactive compounds, selected from organometallic complexes of transition metals, rare earth metals, lanthanides and actinides.
Type:
Grant
Filed:
October 11, 2021
Date of Patent:
September 26, 2023
Assignee:
Merck Patent GmbH
Inventors:
Gaëlle Béalle, Christoph Leonhard, Hsin-Rong Tseng, Irina Martynova, Aurélie Ludemann, Edgar Kluge, Anja Jatsch, Manuel Hamburger, Li Wei Tan, Pawel Miskiewicz, Philip Edward May, Daniel Walker
Abstract: The present invention relates to a liquid crystal (LC) medium comprising a compound of formula I and one or more compounds selected from the group of compounds of the formulae IIA, IIB, IIC and IID, as defined in claim 1, and to the use thereof for optical, electro-optical and electronic purposes, in particular in LC displays, especially in IPS, FFS, VA or PS-VA displays.
Abstract: An electronic switching device, in particular tunnel junctions, containing an organic molecular layer for use in memory, sensors, field-effect transistors or Josephson junctions. More particularly, related to the field of random access non-volatile memristive memories (RRAM). Another aspect is a compound of formula I for use in a molecular layer. Also, the use of the molecular layer and processes for the production and operation of an electronic switching element and components based thereon.
Type:
Application
Filed:
March 15, 2023
Publication date:
September 21, 2023
Applicant:
Merck Patent GmbH
Inventors:
Peer KIRSCH, Henning SEIM, Frank VOGES, Holger HEIL
Abstract: Novel crystalline forms of 4-1(7-chloro-2-methoxybenzo[bll 1,5]naphthyridin-10-yl)aminol-2,6-bis(pyrrolidin-l-%Ilmethyl)phenol and salts thereof are useful, in particular for pharmaceutical formulations. Processes can be used for manufacturing the crystalline forms, and the crystalline forms can be used in methods of treatment.
Abstract: The present invention relates to a liquid crystal (LC) medium comprising a compound of formula I and one or more compounds of formula II as defined in claim 1, and to the use thereof for optical, electro-optical and electronic purposes, in particular in LC displays, especially in IPS, FFS, VA or PS-VA displays.
Abstract: A steerable antenna having a plurality of radiating elements and a plurality of modifier elements configured for shifting phase and/or adjusting amplitude of a signal to be emitted by the radiating elements is disclosed. Each of the radiating elements is coupled to one of the modifier elements, wherein the modifier elements each comprise a liquid crystalline medium and wherein the modifier elements are configured such that the adjustment of the phase and/or amplitude is dependent on a state of the liquid crystalline medium. The steerable antenna further comprises a signal generator connected to the modifier elements and configured for generating a signal suited for dielectric heating of the liquid crystalline media of the modifier elements. Further aspects relate to a method for heating and/or controlling the temperature of the liquid crystalline medium of such a steerable antenna.
Type:
Application
Filed:
June 7, 2021
Publication date:
September 21, 2023
Applicant:
MERCK PATENT GMBH
Inventors:
Michael WITTEK, Carsten FRITZSCH, Dagmar KLASS
Abstract: Polymerizable compounds, processes and intermediates for their preparation, compositions containing them, polymers made from the compounds or compositions, and uses of the polymerizable compounds, compositions and polymers.
Type:
Grant
Filed:
March 29, 2021
Date of Patent:
September 19, 2023
Assignee:
MERCK PATENT GMBH
Inventors:
Thorsten Kodek, Oliver Heppert, Timo Uebel, Rocco Fortte, Leo Weegels
Abstract: The present invention relates to fluorene derivatives and to electronic devices in which these compounds are used as matrix material in the emitting layer and/or as hole-transport material and/or as electron-blocking or exciton-blocking material and/or as electron-transport material.
Abstract: The present invention relates to liquid-crystalline media comprising one or more mesogenic compounds of formula I as set forth hereinafter, wherein the one or more compounds of formula I are contained in the medium in an amount, based on the overall contents of the medium, of at least 15% by weight. The present invention further relates to a switching layer, a switching element and a window element containing the liquid-crystalline medium.
Type:
Grant
Filed:
December 3, 2018
Date of Patent:
September 19, 2023
Assignee:
Merck Patent GmbH
Inventors:
Michael Junge, Andreas Beyer, Mila Fischer, Ewa Ptak
Abstract: To provide a siliceous film manufacturing composition that can fill a narrow and a high aspect ratio trench and can produce a thick siliceous film. [Means for Solution] The present invention provides a siliceous film manufacturing composition that comprises, (a) a block copolymer having a linear and/or cyclic polysilane backbone block with or more silicon atoms and a polycarbosilane backbone block with or more silicon atoms, and (b) a solvent.
Abstract: Devices for the regulation of light transmission and in particular switchable windows, including window elements containing a switchable optical cell having a homeotropically aligned liquid crystal layer with a pretilt angle in the range of 77° to 88°.
Abstract: B7-H6-based compounds disclosed herein have favorable characteristics. Pharmaceutical compositions containing such a compound, the use of such compounds, and treatment with such pharmaceutical compositions are also disclosed. Methods for preparing a compound with an increased affinity for NKp30 are provided.
Type:
Application
Filed:
August 31, 2021
Publication date:
September 14, 2023
Applicant:
Merck Patent GmbH
Inventors:
Stefan Zielonka, Lars Toleikis, Simon Krah, Lukas Pekar
Abstract: The present application relates to a rack (1) for holding a plurality of petri-dishes (P), comprising a main body (2) with a plurality of adjacent and spaced apart holding portions (3) each configured to receive and support, in a substantially parallel orientation that is substantially perpendicular to a longitudinal direction (X) of the rack (1), a petri-dish (P), wherein each holding portion (3) includes positioning features (4) for positioning the petri-dish (P) in the holding portion (3) and allowing insertion of the petri-dish (P) from a lateral side in a direction substantially perpendicular to the longitudinal direction (X). The holding portions (3) and positioning features (4) respectively comprise a pair of separation elements (11) spaced apart from each other to define therebetween a slot (12) configured to receive the petri-dish (P).