Abstract: The present invention relates to surface-modified silica particles comprising an alkoxy organosilane and to compositions comprising such particles as well as to uses of such surface-modified silica particles and compositions comprising such particles.
Abstract: A polymerisable LC material comprising at least one di- or multireactive mesogenic compound and at least one compound of formula CO-1, wherein R1, R2, L1, L2, L3, and n have the meanings as given in claim 1. Furthermore, a method for preparation of the LC material, a polymer film with improved thermal durability obtainable from the corresponding polymerisable LC material, a method of preparation of such polymer film, and the use of such polymer film and said polymerisable LC material for optical, electro-optical, decorative or security devices.
Abstract: The present invention relates to a method for producing purified water comprising a step of passing water through a mixed bed ion exchanger comprising beads having a diameter of less than 0.5 mm, as well as to a module comprising an ultrafiltration means and a mixed bed ion exchanger as defined above and a water treatment system for producing ultrapure water comprising ultrafiltration means and a mixed bed ion exchanger as defined above, wherein the ultrafiltration means is located upstream of said mixed bed ion exchanger.
Abstract: Describe herein is a composition comprising: an acrylic polymer comprising repeat units selected from ones having structure (1), (2), (3), (4), (5), (6), and (7) wherein these repeat units are present in said acrylic polymer in the mole % ranges as described herein; a Novolak resin having a dissolution rate in 0.26 N aqueous TMAH of at least 50 ?/sec; a diazonaphthoquinone (DNQ) photoactive compound (PAC); and an organic spin casting solvent, and a process of using said composition as a positive photoresist developable in aqueous base.
Type:
Grant
Filed:
November 12, 2020
Date of Patent:
November 21, 2023
Assignee:
Merck Patent GmbH
Inventors:
Weihong Liu, Ping-Hung Lu, Chunwei Chen, Medhat A. Toukhy
Abstract: The present invention relates to interference pigments based on platelet-shaped substrates which are coated with at least four high refractive layers and to the use thereof, inter alia in paints, coatings, printings inks, plastics and in particular in cosmetic formulations. The interference pigments show a moderate chroma and can be used as effect pigments, as filler pigments and as protection agent against near infrared radiation, VIS and high energy light.
Type:
Grant
Filed:
March 14, 2018
Date of Patent:
November 21, 2023
Assignee:
Merck Patent GmbH
Inventors:
Michael Termer, Jutta Zur Lage, Anett Moschner, Lilia Heider
Abstract: Filtration head (1) for a filter system, comprising base (2) including filter support (3) for removable filter element (4) and a fluid path from one side of filter element (4) on filter support (3), through filter element (4), and to drainage outlet (5) of base (2), and holder device (6) for removably attaching funnel (7) to base (2) to form a sample fluid reservoir on one side of filter element (4), wherein holder device (6) comprises ring-shaped element (8) configured to extend about bottom peripheral flange (7a) surrounding a lower end of funnel (7) and to selectively apply a biasing force on a radially outward protruding portion (7b) of bottom peripheral flange (7a) of funnel (7) to press funnel (7) against base (2). The filtration head allows the use of cardboard funnels without risk of liquid leakage between the funnel and the base.
Abstract: The present invention relates to cellulose based papers coated with nitrocellulose as well as to methods for producing such coated papers and methods for using them, especially in lateral flow applications.
Type:
Application
Filed:
September 28, 2021
Publication date:
November 16, 2023
Applicant:
MERCK PATENT GMBH
Inventors:
Tina BOCK, Markus BIESALSKI, Marcel KRAUSSE, Tobias MECKEL, Dieter SPIEHL
Abstract: The present invention relates to a process of preparing polyfluoroether compounds with unsaturated end groups and to compounds prepared by said process.
Type:
Application
Filed:
September 6, 2021
Publication date:
November 16, 2023
Applicant:
MERCK PATENT GMBH
Inventors:
Reiner FRIEDRICH, Fabian KOCH, Laura SCHIMURA
Abstract: The present invention relates to a process for the preparation of fluorinated compounds, to novel compounds containing fluorinated end groups, to the use thereof and to compositions comprising novel compounds containing fluorinated end groups.
Abstract: The present invention relates to polypeptides binding Aggrecan as well as ADAMTS5 and/or MMP13, more in particular to polypeptides that comprise or essentially consist of immunoglobulins binding Aggrecan as well as immunoglobulins binding ADAMTS5 and/or immunoglobulins binding MMP13 (also referred to herein as “polypeptides of the invention”, and “immunoglobulin(s) of the invention”, respectively).
Type:
Grant
Filed:
June 4, 2018
Date of Patent:
November 14, 2023
Assignees:
MERCK PATENT GMBH, ABLYNX NV
Inventors:
Soren Steffensen, Gerald Beste, Hans Guehring, Lars Toleikis, Christoph Ladel, Sven Lindemann, Roland Kellner, Ralf Guenther
Abstract: The present invention relates to a composition comprising at least one nanosized light emitting material and at least compound represented by the following general formula (1) or (2), wherein Z is P, As or Sb and R1, R2, R3, R4, R5 and R6 are, identically or differently, selected from alkyl groups, aryl groups, heteroaryl groups, aralkyl groups, heteroaralkyl groups, alkaryl groups and alkheteroaryl groups,
Abstract: A liquid crystal medium containing a) one or more compounds of formula I b) one or more compounds of the formula IIBa and c) one or more compounds of the formula IIDa and the use thereof for optical, electro-optical and/or electronic purposes, in particular in LC displays, especially in IPS, FFS, VA or PS-VA displays.
Abstract: The present invention relates to a method for producing purified water comprising a step (a) of passing water through a mixed bed ion exchanger comprising beads having a diameter between 0.2 and 0.7 mm and a step (b) of passing water through a fibrous ion-exchange material. The invention further relates to a module comprising the mixed bed ion exchange resin and the fibrous material and to a water treatment system for producing ultrapure water comprising the mixed bed ion exchange resin and the fibrous material.
Abstract: Alpha-amino boronic acid derivatives are useful for selectively inhibiting the activity of immunoproteasome subunit LMP7 and for the treatment of medical conditions affected by immunoproteasome activity such as blood disorders and solid tumors, which are defined by specific genetic alterations and/or inadequate responsiveness to other therapeutic treatments. In particular, the compounds disclosed herein are selective LMP7 inhibitors, which may be useful alone or in combination for the treatment of blood disorders, such as multiple myeloma, and certain solid tumors.
Type:
Application
Filed:
October 5, 2021
Publication date:
November 2, 2023
Applicant:
Merck Patent GmbH
Inventors:
Christina ESDAR, Manja FRIESE-HAMIM, Michael SANDERSON, Gina WALTER-BAUSCH
Abstract: A liquid-crystal (LC) media having a negative dielectric anisotropy containing a compound of formula I and the use of the LC media for optical, electro-optical and electronic purposes, in particular in energy-efficient LC displays, especially in IPS, FFS, VA or PS-VA displays.
Abstract: A liquid-crystalline (LC) media having positive dielectric anisotropy and tliquid-crystal displays (LCDs) containing these media, especially to displays addressed by an active matrix and in particular to energy efficient LC displays of the TN, PS-TN, STN, TN-TFT, OCB, IPS, PS-IPS, FFS, HB-FFS, XB-FFS, PS-FFS, SA-HB-FFS, SA-XB-FFS, polymer stabilised SA-HB-FFS, polymer stabilised SA-XB-FFS, positive VA or positive PS-VA type.
Type:
Application
Filed:
March 20, 2023
Publication date:
October 26, 2023
Applicant:
MERCK PATENT GMBH
Inventors:
Sven Christian LAUT, Hee-Kyu LEE, Jing WANG
Abstract: The present invention relates to a metal effect pigment-free radar-compatible coating on a substrate, to a process for the production of such a coating, and to the use of such a coating, in particular in vehicle construction.
Abstract: The present invention relates to combination therapies useful for the treatment of cancer. In particular, the invention relates to the combined use of a PD-1 inhibitor, a TGF? inhibitor, and a TIGIT inhibitor to treat cancer.
Abstract: The present application relates to biotechnological fluid treating, such as biopharmaceutical liquids in order to obtain products such as monoclonal antibodies, vaccines or recombinant proteins, and particularly to a system for treating a biotechnical fluid, having a bioprocess machine and at least one bioprocess machine helper, configured to connect to each other and each comprising a controller, in turn comprising a machine-to-machine communication tool configured for connecting to a network
Type:
Application
Filed:
August 19, 2021
Publication date:
October 26, 2023
Applicant:
MERCK PATENT GMBH
Inventors:
Rene REINBIGLER, Denis DUBRET, Steven MILLER
Abstract: The invention relates to a polymerizable LC material comprising one or more reactive mesogenic compounds, one or more chiral compounds and one or more compounds of formula I, wherein the individual radicals have one of the meaning as given in the claims. Furthermore, the present invention relates also to a method for its preparation, a polymer film with improved thermal and UV stability obtainable from a corresponding polymerizable LC material, to a method of preparation of such polymer film, and to the use of such polymer film and said polymerizable LC material in optical, electro-optical, decorative or security devices.
Type:
Application
Filed:
September 23, 2021
Publication date:
October 26, 2023
Applicant:
Merck Patent GmbH
Inventors:
Stephen MULCAHY, Owain Llyr PARRI, Sarabjot KAUR