Patents Assigned to Merck Patent GmbH
  • ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF
    Publication number: 20240010749
    Abstract: Antibodies which bind human CEACAM5 protein, as well as isolated nucleic acids and host cells containing a sequence encoding said antibodies are disclosed. Immunoconjugates containing said antibodies linked to a growth-inhibitory agent, and pharmaceutical compositions containing antibodies or said immunoconjugates are also disclosed. A use of the antibodies, immunoconjugates, and pharmaceutical compositions disclosed herein is provided for the treatment of cancer or for diagnostic purposes.
    Type: Application
    Filed: August 13, 2021
    Publication date: January 11, 2024
    Applicant: Merck Patent GmbH
    Inventors: Jan ANDERL, Sabine RAAB-WESTPHAL, Stefan HECHT, Carl DEUTSCH, Min SHAN, Doreen KÖNNING, Willem N. SLOOT, Felix HART, Christian SCHRÖTER, Lars TOLEIKIS, Nir BERGER
  • TETRAZOLE DERIVATIVES
    Publication number: 20240009175
    Abstract: Substituted tetrazole derivatives are useful for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases.
    Type: Application
    Filed: March 16, 2021
    Publication date: January 11, 2024
    Applicants: Merck Patent GmbH, RYVU THERAPEUTICS S.A.
    Inventors: Thomas FUCHSS, Lisa Koetzner, Christina Schindler, Daniel Kuhn
  • Negative type photosensitive siloxane composition and methods for producing cured film and electronic device using the same
    Patent number: 11868048
    Abstract: [Object] To provide a negative type photosensitive siloxane composition capable of forming a cured film excellent in heat resistance and critical thickness for cracking [Means] The present invention provides a negative type photosensitive siloxane composition comprising: a polysiloxane containing silanol in a specific content, a particular photo base generator, and a solvent. The content of silanol is measured by FT-IR.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: January 9, 2024
    Assignee: Merck Patent GmbH
    Inventor: Masanobu Hayashi
  • Polycarbosilazane, and composition comprising the same, and method for producing silicon-containing film using the same
    Patent number: 11866554
    Abstract: To provide a new silicon-containing polymer making it possible to form a cured film has features that its residual stress is small and crack resistance is high. A polycarbosilazane having particular cyclic structures.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: January 9, 2024
    Assignee: Merck Patent GmbH
    Inventors: Katsuchika Suzuki, Toshiya Okamura, Tetsuo Okayasu, Thorsten Vom Stein
  • Filtration head for a filter system and funnel for use in conjunction with a filtration head
    Patent number: 11865477
    Abstract: Filtration head (1) for a filter system, comprising base (2) including filter support (3) for removable filter element (4) and a fluid path from one side of filter element (4) on filter support (3), through filter element (4), and to drainage outlet (5) of base (2), and holder device (6) for removably attaching funnel (7) to base (2) to form a sample fluid reservoir on one side of filter element (4), wherein holder device (6) comprises ring-shaped element (8) configured to extend about bottom peripheral flange (7a) surrounding a lower end of funnel (7) and to selectively apply a biasing force on a radially outward protruding portion (7b) of bottom peripheral flange (7a) of funnel (7) to press funnel (7) against base (2). The filtration head allows the use of cardboard funnels without risk of liquid leakage between the funnel and the base.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: January 9, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Didier Metz, Marisa Hohnadel
  • Polysiloxane, composition comprising the same and cured film using the same
    Patent number: 11866553
    Abstract: [Problem] To provide a polysiloxanecapable of forming a cured film of a thick film with high heat resistance, a composition comprising the polysiloxane, and a method of manufacturing a cured film using the composition. [Means for Solution] To provide a polysiloxane comprising a repeating unit represented by the following formula (Ib), wherein R2 is each independently hydrogen, alkyl, aryl, alkenyl, and the like, a composition comprising the polysiloxane, and a method of manufacturing a cured film using the composition.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: January 9, 2024
    Assignee: Merck Patent GmbH
    Inventors: Naofumi Yoshida, Megumi Takahashi, Seishi Shibayama, Katsuto Taniguchi, Masanobu Hayashi, Toshiaki Nonaka
  • COMPOSITION
    Publication number: 20240002688
    Abstract: The present invention relates to a composition comprising at least one light emitting moiety.
    Type: Application
    Filed: October 18, 2021
    Publication date: January 4, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Yuki HIRAYAMA, Tadashi KISHIMOTO, Tomohisa GOTO, Hiromoto SATO, Nils GREINERT, Teruaki SUZUKI
  • LIQUID-CRYSTAL MEDIUM
    Publication number: 20240002728
    Abstract: A liquid-crystal (LC) material having negative dielectric anisotropy and the use thereof for optical, electro-optical and electronic purposes, such as for example in LC displays, in particular energy saving displays based on the ECB, IPS or FFS effect, where the liquid crystal medium contains one or more compounds of formula I and one or more compounds compounds of formulae IIA, IIB, IIC and IID
    Type: Application
    Filed: June 22, 2023
    Publication date: January 4, 2024
    Applicant: Merck Patent GmbH
    Inventors: Chi-Shun HUANG, Sven Christian LAUT, Hee-Kyu LEE, Minghui YANG, Harald HIRSCHMANN, Kuang-Ting CHOU, Shih-Chieh HUNG, Alexander HAHN, Philipp WUCHER
  • FERROELECTRIC NEMATIC LIQUID CRYSTALLINE MEDIUM
    Publication number: 20240002727
    Abstract: The new LC media exhibit a ferroelectric nematic phase at ambient temperature. They comprise at least one or more compounds selected from each of formula IA, of formula IB and of the group of formulae IC-1/IC-2/IC-3, in which the variable groups have the meanings indicated in the text and in the claims. The mixtures are useful for electro-optics, electronics, electro-mechanic and other applications for materials with very high dielectric permittivity and other energy-saving applications.
    Type: Application
    Filed: November 30, 2021
    Publication date: January 4, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Matthias BREMER, Atsutaka MANABE, Martin KRASKA
  • Method for processing a predetermined computing task by a distributed, vehicle-based computing system and a corresponding computing system
    Patent number: 11858372
    Abstract: A method is provided for processing a predetermined computing task by a distributed, vehicle-based computing system. By a server device, the computing task is divided into several data packets with respective computing data for a respective part of the computing task. The method includes that at least one motor vehicle is determined, which currently is in a predetermined ready state, and, in case it is in the predetermined ready state, the server device transmits to the motor vehicle at least one of the data packets and the motor vehicle processes the respective computing data of the at least one transmitted data packet. The vehicle generates a respective computing result related to the data packet and transmits this computing result to the server device.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: January 2, 2024
    Assignee: Merck Patent GmbH
    Inventors: Martin Hauschild, Joachim Kolling, James Kugler, David Martin
  • Boronic acid derivatives
    Patent number: 11858951
    Abstract: ?-Amino boronic acid derivatives are useful for inhibiting the activity of immunoproteasome (LMP7) and for the treatment and/or prevention of medical conditions affected by immunoproteasome activity such as inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases, and cancer.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: January 2, 2024
    Assignee: Merck Patent GmbH
    Inventors: Markus Klein, Oliver Schadt, Christina Esdar
  • Substrate pattern filling composition and use of the same
    Patent number: 11859152
    Abstract: To provide a substrate pattern filling composition capable of suppressing pattern collapse and a method for using the same. A substrate pattern filling composition comprising a first solute (A), a second a solute (B) and a solvent (C), and a method for using the same.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: January 2, 2024
    Assignee: Merck Patent GmbH
    Inventors: Yuko Horiba, Hiroko Kuboki, Tatsuro Nagahara
  • Positive type photosensitive siloxane composition and cured film formed by using the same
    Patent number: 11860537
    Abstract: [Object] To provide a positive type photosensitive composition capable of forming a cured film having high transparency [Means] The present invention provides a positive type photosensitive siloxane composition comprising: a polysiloxane, a diazonaphthoquinone derivative, an additive having a >N—C(?O)— or >N—C(?S)— structure and the capability of interacting with the polysiloxane, and a solvent. The polysiloxane and the additive interact with each other before exposure, but they lose the interaction after exposure.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: January 2, 2024
    Assignee: Merck Patent GmbH
    Inventors: Naofumi Yoshida, Megumi Takahashi, Katsuto Taniguchi
  • Surface coating compositions
    Patent number: 11859100
    Abstract: The present invention relates to new coating compositions for the preparation of functional surface coatings on various base material substrates. The coating compositions are based on a silazane-containing polymer and a non-polymeric phenolic compound comprising at least two and not more than four aromatic units in its molecular structure. The coating compositions provide improved physical and chemical surface properties and may be applied by user-friendly coating methods.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: January 2, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Ralf Grottenmueller, Yvonne Ott, Martin Roeder
  • COVER FOR A THIN-LAYER CHROMATOGRAPHY DEVELOPMENT CHAMBER
    Publication number: 20230417716
    Abstract: A thin-layer chromatography development chamber (1) that can be used for developing thin-layer chromatography plates (21) by introducing a liquid solvent onto a sample arranged on the surface of a thin-layer chromatography plate (21), whereby the solvent and the thin-layer chromatography plate (21) can be inserted into the development chamber (1), comprises a housing (2) with an opening (3). The opening (3) of the development chamber (1) can be closed with a cover (4) that comprises a data input unit (10) for entering or collecting data related to a development process performed within the development chamber (1). The cover (4) further comprises a data communication unit (16) that enables a wireless data transmission of the data related to the development process to a thin-layer chromatography data storage device (24).
    Type: Application
    Filed: November 12, 2021
    Publication date: December 28, 2023
    Applicant: MERCK PATENT GMBH
    Inventors: Michaela OBERLE, Eric SCHUNDA, Robert FISCHER
  • Materials for electronic devices
    Patent number: 11856849
    Abstract: Compounds of formula (1) that have functional substituents in a specific spatial arrangement, and electronic devices that include a compound of formula (1), and to the preparation of compounds of formula (1).
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: December 26, 2023
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Irina Martynova, Anja Jatsch, Thomas Eberle, Jonas Kroeber, Christof Pflumm
  • Method of treating bone metastasis diseases, medicaments therefore, and a method of predicting the clinical outcome of treating bone metastasis diseases
    Patent number: 11851492
    Abstract: A method is used for treating bone metastasis diseases in subjects. The method preferably depends on whether the subject shows certain specific proteins levels in one or more body fluids prior to or during treatment. The treatment includes the administration of at least one pan ?v integrin inhibitor to a subject, a medicament for use in said new methods, and a method of predicting the outcome of a treatment with at least one pan ?v integrin inhibitor based on the specific protein levels in one or more body fluids of the subject.
    Type: Grant
    Filed: March 14, 2022
    Date of Patent: December 26, 2023
    Assignee: Merck Patent GmbH
    Inventors: Josef Straub, Eike Staub
  • Polymerisable liquid crystal material and polymerised liquid crystal film
    Patent number: 11851601
    Abstract: A polymerisable LC material containing one or more di- or multireactive mesogenic compounds, and one or more compounds of formula TRI, and one or more compounds of formula ND Furthermore, a method for preparing the polymerisable LC material, and a polymer film with improved thermal durability and UV stability obtainable from the polymerisable LC material, and a method of preparing such polymer film, and using such polymer film and the polymerisable LC material for optical, electro-optical, decorative or security devices.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: December 26, 2023
    Assignee: Merck Patent GmbH
    Inventors: Yong-Hyun Choi, Jae-Hyun Kang, Hyun-Jin Yoon
  • Polymerizable LC material and polymer film
    Patent number: 11851600
    Abstract: An optical component and a electro optical devices comprising the optical component. Further, a cholesteric polymerizable liquid crystalline (LC) material, preferably utilized in an optical component in accordance with the present invention, a process for the production of the cholesteric polymerizable LC material, a process to convert the cholesteric polymerizable material into a polymer film, a polymer film obtainable from the cholesteric polymerizable LC material, and the use of the polymer films in an optical component or device comprising a polymer film.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: December 26, 2023
    Assignee: Merck Patent GmbH
    Inventors: Stephen Mulcahy, Owain Llyr Parri
  • METHOD FOR VARIABLY ADJUSTING THE ELECTRICAL INSULATING PROPERTIES OF VARISTOR-CONTAINING MATERIALS
    Publication number: 20230407052
    Abstract: The present invention relates to a process for the variable adjustment of the electrical insulation properties of varistor-containing composite materials with the aid of defined filler mixtures, to the use of such filler mixtures, and to composite materials having resistive and capacitive field-control properties comprising filler mixtures of this type.
    Type: Application
    Filed: November 12, 2021
    Publication date: December 21, 2023
    Applicant: MERCK PATENT GMBH
    Inventors: Johann BAUER, Tanja DELP