Patents Assigned to Merck Patent GmbH
  • Publication number: 20240317753
    Abstract: Tricyclic heterocycles are disclosed. These heterocyclic compounds are useful as TEAD binders and/or inhibitors of YAP-TEAD and TAZ-TEAD protein-protein interaction or binding and for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases, in particular cancer.
    Type: Application
    Filed: May 5, 2021
    Publication date: September 26, 2024
    Applicants: Merck Patent GmbH, Cancer Research Technology Ltd.
    Inventors: Timo HEINRICH, Sarah Schlesiger, Jakub Gunera, Emma Carswell, Lisa Koetzner, Andreas Blum
  • Patent number: 12099305
    Abstract: The disclosed subject matter relates to a rinse and methods of use thereof for removing an edge protection layer and residual hardmask components (e.g., metals) from the edge and at least one proximate surface of a wafer/substrate where the rinse includes acetic acid and/or a halogenated acetic acid of structure (A) wherein R1 and R2 are independently hydrogen or a halogen and R3 is a halogen and (ii) a compound having structure (B) wherein each of Ra, Rb, Rc, Rd, Re, Rf, Rg and Rh may independently be hydrogen, a substituted or an unsubstituted alkyl group, a substituted or an unsubstituted halogenated alkyl group, a substituted or an unsubstituted alkyl carbonyl group, a halogen, and a hydroxy group.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: September 24, 2024
    Assignee: Merck Patent GmbH
    Inventors: M. Dalil Rahman, Salem Mullen, JoonYeon Cho
  • Patent number: 12084438
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: September 10, 2024
    Assignees: Merck Patent GmbH, Vertex Pharmaceuticals Incorporated
    Inventors: Matthew Bleich, Jean-Damien Charrier, Huijun Dong, Steven Durrant, Meredith Suzanne Eno, Gorka Etxebarria I Jardi, Simon Everitt, Damien Fraysse, Ronald Knegtel, Igor Mochalkin, Kiri North, Filippos Porichis, Hui Qiu, Robert Pullin, Pierre-Henri Storck, Heather Clare Twin, Yufang Xiao
  • Patent number: 12083486
    Abstract: A mixing device (1) for cyclically imparting a force on an external surface (A) of a bag (B) for agitating a content (C) of the bag (B), the mixing device (1) comprising a lever (2) supported so as to be able to pivot about a pivot (3), a weight (4) provided on a first side of the lever (2), a driver (5) arranged to cooperate with the lever (2), a motor (6) for moving the driver (5) to lift the first side of the lever (2) with the weight (4) against gravity and to drop the first side against the external surface (A) of the bag (B), and a holder (7) for supporting the mixing device (1) such that the first side of the lever (2) can contact the external surface (A) of the bag (B) in the drop motion.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: September 10, 2024
    Assignee: Merck Patent GmbH
    Inventors: Stephane Olivier, Gaetan Bour
  • Patent number: 12077727
    Abstract: [Problem] To provide a semiconductor aqueous composition capable of preventing a pattern collapse and suppressing a bridge defect. [Means for Solution] A semiconductor aqueous composition comprising a single or plurality of surfactant(s) having a monovalent anion part represented by formula (I): Chain 1-X1—X2-Chain 2 (I) wherein, X1 and X2 are each independently —C(=0)- or —S(=0)2-, and Chain 1 and Chain 2 are each independently a linear or branched C1-20 alkyl, wherein one or more H in said C1-20 alkyl are replaced by F, and one or more methylenes in Chain 1 may be replaced by -0-, with the proviso that Chain 1 and Chain 2 may be bonded to form a ring structure) and a monovalent cation part other than hydrogen ion; and water.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: September 3, 2024
    Assignee: Merck Patent GmbH
    Inventors: Kazuma Yamamoto, Maki Ishii, Tatsuro Nagahara
  • Patent number: 12077703
    Abstract: The present invention relates to heteroaromatic isothiocyanates of formula N as defined in claim 1, to liquid-crystalline media comprising one or more compounds of formula N and to high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, e.g. phased array antennas.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: September 3, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Amir Hossain Parham, Constanze Brocke, Carsten Fritzsch, Dagmar Klass
  • Patent number: 12077541
    Abstract: The present application relates to an amine compound according to formula (I), (II) or (III) which is suitable for use in electronic devices.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: September 3, 2024
    Assignee: Merck Patent GmbH
    Inventors: Ilona Stengel, Florian Maier-Flaig, Philipp Harbach, Elvira Montenegro, Aurélie Ludemann
  • Patent number: 12078273
    Abstract: The disclosure herein relates to a flow path comprising half clamps 1 having an interior surface surrounding a flexible tubing 3 connection with a barb adapter 3, when assembled may be placed within a clamshell reduce or prevent deformation of the flexible tubing.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: September 3, 2024
    Assignee: Merck Patent GmbH
    Inventors: Olivier Flick, Robert Langlois, James Vigna, Christine Crequy, Thomas Coton
  • Publication number: 20240287102
    Abstract: A solid form of [(1R)-2-(1-benzofuran-3-yl)-1-{[(1S,2R,4R)-7-oxabicyclo[2.2.1]heptan-2-yl]formamido}ethyl]boronic acid, hydrates, solvates, and/or adducts thereof can be used as LMP7 inhibitors. The solid form can be a trimeric crystalline anhydrous form characterized by two or more 2? XRPD peaks at 6.5±0.2°, 11.2±0.2°, 17.1±0.2°, 19.6±0.2°, and 21.9±0.2° degrees.
    Type: Application
    Filed: July 28, 2022
    Publication date: August 29, 2024
    Applicant: Merck Patent GmbH
    Inventors: Delia-Maria GRUIA, Markus Klein, Michael Lange
  • Publication number: 20240287177
    Abstract: VHH-based NKp30 binders are provided having favorable characteristics. Moreover, pharmaceutical compositions including such a compound are produced and methods of medical treatment with such compounds and pharmaceutical compositions are developed. In a compound including a VHH antibody domain or fragment thereof, the VHH antibody domain or fragment thereof can have complementary determining regions CDR1, CDR2, and CDR3 of one of VHH1 to VHH16, or a humanized modification thereof, or a modification involving replacement, addition, and/or deletion of up to three amino acids in each complementary determining region.
    Type: Application
    Filed: June 22, 2022
    Publication date: August 29, 2024
    Applicant: Merck Patent GmbH
    Inventors: Stefan ZIELONKA, Lars Toleikis, Simon Krah, Lukas Pekar, Andreas Evers
  • Patent number: 12071565
    Abstract: The present invention relates to a display device, in particular a backlit display device having a visible side and a back side, which appears opaque in colour and texture on viewing of the visible side without backlighting, but, with the backlighting switched on, is sufficiently transparent that the transmission of information by the light source from the back side is possible, and to the production of a display device of this type and to the use thereof.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: August 27, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Sabine Eberle, Udo Gumsheimer
  • Patent number: 12071405
    Abstract: The present application relates to compounds of formula (I) containing a group selected from amino groups, bridged amino groups and carbazole groups, to processes for preparation thereof, and to the use thereof in electronic devices, and in particular OLEDs.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: August 27, 2024
    Assignee: Merck Patent GmbH
    Inventors: Elvira Montenegro, Teresa Mujica-Fernaud, Florian Maier-Flaig, Frank Voges
  • Publication number: 20240277645
    Abstract: The disclosed technology relates to a continuous impregnating process of active pharmaceutical ingredients (API) onto porous carriers, a continuous impregnation process for making impregnated porous carrier particles and pharmaceutical dosage forms comprising impregnated porous carrier particles, impregnated porous carrier particles and pharmaceutical dosage forms comprising impregnated porous carrier particles prepared by the continuous impregnation process.
    Type: Application
    Filed: June 13, 2022
    Publication date: August 22, 2024
    Applicants: MERCK PATENT GMBH, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Fernando J. MUZZIO, Benjamin J. GLASSER, Thamer A. OMAR, Andrés D. ROMÁN-OSPINO, Gudrun BIRK
  • Publication number: 20240277711
    Abstract: cMET inhibitors can be used in the treatment of glioblastoma, including disseminated glioblastoma harboring MET amplification.
    Type: Application
    Filed: June 2, 2022
    Publication date: August 22, 2024
    Applicant: Merck Patent GmbH
    Inventors: Claudia-Nanette GANN, Ilhan Celik, Nazanin Majd, John Frederick de Groot, Michael Weller
  • Publication number: 20240279550
    Abstract: Reactive mesogens (RMs) derived from tolane, mixtures and formulations comprising them, polymers obtained from such RMs and RM mixtures, and the use of the RMs, RM mixtures and polymers in optical or electrooptical components or devices.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 22, 2024
    Applicant: Merck Patent GmbH
    Inventors: Kevin Adlem, Owain Llyr Parri, Alex Davis, Stephen Mulcahy, Philipp Wucher, Beate Schneider
  • Patent number: 12068150
    Abstract: [Problem] To obtain a substrate cleaning solution capable of cleaning a substrate and removing particles. [Means for Solution] The present invention is a substrate cleaning solution comprising an insoluble or hardly soluble solute (A), a soluble solute (B), and a solvent (C).
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: August 20, 2024
    Assignee: Merck Patent GmbH
    Inventors: Takafumi Kinuta, Tatsuro Nagahara, Yuko Horiba
  • Patent number: 12065431
    Abstract: The present invention describes amines with dibenzofuran, dibenzothiophene and fluorene groups, especially for use as triplet matrix materials in organic electroluminescent devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.
    Type: Grant
    Filed: December 29, 2021
    Date of Patent: August 20, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Amir Hossain Parham, Thomas Eberle, Anja Jatsch, Tobias Grossmann, Jonas Valentin Kroeber, Elvira Montenegro, Caroline Wern
  • Patent number: 12065536
    Abstract: The invention relates to polymers having at least one repeating unit of the following formula (I): wherein Ar1, Ar2, Ar3 and Ar4, R and X, and a, b, c, d, e and f can have the meanings defined in claim 1, to processes for the preparation thereof and to the use thereof in electronic or optoelectronic devices, in particular in organic electroluminescent devices, so-called OLEDs (OLED?Organic Light Emitting Diodes). The present invention also relates to electronic or optoelectronic devices, in particular organic electroluminescent devices, which contain said polymers.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: August 20, 2024
    Assignee: Merck Patent GmbH
    Inventors: Nils Koenen, Dominik Joosten, Beate Burkhart, Katja Scheible, Miriam Engel, Holger Heil
  • Publication number: 20240270748
    Abstract: Tricyclic heterocycles are useful as TEAD binders and/or inhibitors of YAP-TEAD. Tricyclic heterocycles can be used for TAZ-TEAD protein-protein interaction or binding and for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases, in particular cancer.
    Type: Application
    Filed: November 2, 2021
    Publication date: August 15, 2024
    Applicants: Merck Patent GmbH, Cancer Research Technology Ltd.
    Inventors: Timo Heinrich, Sarah Schlesiger, Jakub Gunera, Lisa Koetzner, Emma Carswell, Andreas Blum
  • Publication number: 20240271042
    Abstract: A liquid crystal medium comprising a) one or more compounds of formula I and one or more compounds of the formula T and one or more compounds of the formula S1 and an electronic component comprising said LC medium, operable in the visible (VIS), infrared (IR) or microwave region of the electromagnetic spectrum. Also, the use of said LC medium in the IR, VIS or microwave region and to devices comprising said electronic component.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 15, 2024
    Applicant: Merck Patent GmbH
    Inventors: Izumi Saito, Benjamin Snow