Abstract: A switchable optical device is provided having a first substrate (11), a second substrate (12) and a seal (114). The two substrates (11, 12) and the seal (114) are arranged such that a cell having a cell gap is formed and a switchable medium (10) is located inside the cell gap. The first substrate (11) has a first transparent electrode (21) and the second substrate (12) has a second transparent electrode (22). The electrodes (21, 22) are facing towards the cell gap. The two substrates (11, 12) are arranged such that the first substrate (11) has a first region (71) adjacent to a first edge (41) of the first substrate (11) which does not overlap with the second substrate (12) and the second substrate (12) has a second region (72) which does not overlap with the first substrate (11). A first electrically conducting busbar (31) is arranged in the first region (71) and a second electrically conducting busbar (32) is arranged in the second region (72).

Abstract: The present invention relates to synergistic combinations of DNA-alkylating ADCs and ATR inhibitors.

Abstract: The invention relates to compounds of the formula I, in which R, A, n, L1, L2, L3 and X have the meanings given in Claim 1, to a process for their preparation, and to liquid-crystalline media comprising at least one compound of the formula I and electro-optical displays containing a liquid-crystalline medium of this type.

Abstract: The invention relates to thiazolopyridine derivatives of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative or infectious diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.

Abstract: The present invention is directed to a crystalline sodium salt of 5-methyl-(6S)-tetrahydrofolic acid wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to sodium is from 1:0.5 to 1:1.5 (in mol/mol) and/or hydrates and/or solvates thereof, as well as, a processes of obtaining the same.

Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.

Abstract: The present invention relates to the compounds of the formulae (1) and (2) and to organic electroluminescent devices, in particular blue-emitting devices, in which these compounds are used as host material or dopant in the emitting layer and/or as hole-transport material and/or as electron-transport material.

Abstract: The present invention relates to a liquid crystal (LC) medium comprising a polymerisable compound, to a process for its preparation, to its use for optical, electro-optical and electronic purposes, in particular in LC displays, especially in an LC display of the polymer sustained alignment (PSA) type, and to an LC display, especially a PSA display, comprising it.

Abstract: The present invention relates to a composition comprising a semiconducting light emitting nanoparticle.

Abstract: The present invention relates to novel 5-azaindazole derivatives of formula (I), as described and defined herein, and pharmaceutically acceptable salts, solvates and prodrug thereof, as well as pharmaceutical compositions comprising such compounds. The 5-azaindazole derivatives according to the invention have been found to be highly effective dual A2A/A2B adenosine receptor antagonists, and can thus be used as therapeutic agents, particularly in the treatment or prevention of hyperproliferative or infectious diseases or disorders.

Abstract: The present invention relates to a semiconducting nanoparticle.

Abstract: The present invention relates to heterocyclic compounds, especially for use in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.

Abstract: The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds.

Abstract: A blended composition containing uncoated Al2O3 flakes having a thickness of ?500 nm and a D50-value of 15-30 ?m and a D90-value of 30-45 ?m, and/or coated Al2O3 flakes having a thickness of ?500 nm and a D50-value of 15-30 ?m and a D90-value of 30-45 ?m, which have been coated with at least one layer of a metal oxide, mixtures of at least two metal oxides, metal, metal sulphide, titanium suboxide, titanium oxynitride, FeO(OH), metal alloys and/or rare earth compounds, and their use in various formulations.

Abstract: The present invention relates to the purification of poloxamers to be used as cell culture media additives. Activated carbon can be used to remove hydrophobic high molecular weight components which reduce the efficacy of poloxamers as cell culture additives.

Abstract: The present invention relates to liquid-crystalline media comprising one or more pleochroic compounds, and one or more compounds selected from the group of compounds of formulae I, II and III, in which the groups have the meanings as set forth in claim 1, and to components comprising these media for high-frequency technology, in particular phase shifters and microwave array antennas.

Abstract: The present invention relates to a polymerizable mixture which can be used to form a dielectric material for the preparation of passivation layers in electronic devices. The polymerizable mixture comprises a first monomer and a second monomer which may react to form a copolymer providing excellent film forming capability, excellent thermal properties and excellent mechanical properties. There is further provided a method for forming said copolymers and an electronic device containing said copolymers as dielectric material. Beyond that, the present invention relates to a manufacturing method for preparing a packaged microelectronic structure and to a microelectronic device comprising said packaged microelectronic structure formed by said manufacturing method.

Abstract: Compounds of the formula Ia and Ib in which R1, R2 and R3 have the meanings indicated in claim 1, are inhibitors of ATR, and can be employed for the treatment of diseases such as cancer.

Abstract: The present invention relates to a polymerizable mixture which can be used to form a dielectric material for the preparation of passivation layers in electronic devices. The polymerizable mixture comprises a first monomer and a second monomer which may react to form a copolymer providing excellent film forming capability, excellent thermal properties and excellent mechanical properties. There is further provided a method for forming said copolymers and an electronic device containing said copolymers as dielectric material. Beyond that, the present invention relates to a manufacturing method for preparing a packaged microelectronic structure and to a microelectronic device comprising said packaged microelectronic structure formed by said manufacturing method.

Abstract: The invention relates to a device for cutting tubing, comprising a frame having an entry window and an exit window for defining a pathway of the longitudinal axis of the tube through the device, a cutting element arranged on the frame, wherein the cutting element is arranged lateral and opposite to the pathway of the tubing and wherein at least the portion of the frame is formed mobile and the cutting element is arranged on or opposite to the mobile portion to enable the cutting element to be pressed into the pathway of the longitudinal axis of the tubing.