Abstract: The invention relates to a liquid-crystalline medium, having particular dielectric properties, in that it has: either a dielectric constant perpendicular to the director (??) in the range of 2 or more to less 8 or less and at the same time a ratio of the dielectric constant perpendicular to the director (??) to the dielectric anisotropy (??), i.e. (??/??) of 1.0 or more or or a dielectric constant perpendicular to the director (??) of 8 or more and a dielectric anisotropy (??) of 26 or less and preferably comprises one or more compounds having a high dielectric constant perpendicular to the director (??) and a high average dielectric constant (?av.). These compounds are suitable for use in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect.
Abstract: The invention relates to mesogenic media comprising a first component, component A, consisting of bimesogenic compounds optionally a second component, component B, consisting of nematogenic compounds, preferably selected from the group of compounds of formulae B-I to B-III and optionally a second or third component, component C, consisting of one or more chiral molecules, wherein the parameters have the meaning given in claim 1, to the use of mesogenic media in flexoelectric liquid crystal devices and to those devices comprising a liquid crystal medium according to the present invention.
Type:
Application
Filed:
October 23, 2014
Publication date:
October 13, 2016
Applicant:
Merck Patent GmbH
Inventors:
Rachel TUFFIN, Rebecca PROCTOR, Simon SIEMIANOWSKI, Benjamin SNOW, Owain Llyr PARRI, Kevin ADLEM
Abstract: The present invention is related to a method for the production of single crystalline TiO2 flakes in the rutile crystal structure, to single crystalline TiO2 flakes obtained by this method as well as to the use thereof, especially as pigments in several application media.
Abstract: The invention relates to compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of these compounds of formula I in liquid crystal media and to respective devices comprising a liquid crystal medium according to the present invention and in particular to flexoelectric liquid crystal devices.
Type:
Application
Filed:
October 23, 2014
Publication date:
October 6, 2016
Applicant:
Merck Patent GmbH
Inventors:
Kevin ADLEM, Owain Llyr PARRI, Rachel TUFFIN, Patricia Eileen SAXTON, Mariam NAMUTEBI, Benjamin SNOW, Rebecca PROCTOR, Simon SIEMIANOWSKI
Abstract: The present invention refers to a method for selectively structuring of a polymer matrix comprising AgNWs (silver nano wires) or silver nano particles (Ag nano ink) or comprising mixtures of AgNWs and silver nano particles on a flexible plastic substructure or solid glass sheet. The method also includes a suitable etching composition, which allows to process the method in an industrial scale.
Abstract: The invention relates to protein-adhesive dyes, to the preparation thereof and to preparations comprising same, and to a method for coloring keratin-containing fibers, in particular for coloring human hair.
Abstract: The invention provides novel heterocyclic amines according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Type:
Grant
Filed:
March 10, 2014
Date of Patent:
October 4, 2016
Assignee:
Merck Patent GmbH
Inventors:
Ruoxi Lan, Xiaoling Chen, Yufang Xiao, Bayard R. Huck, Andreas Goutopoulos
Abstract: The invention relates to enantiomerically pure DOTAP chloride and stable crystal modifications of (2R,S)-, (2S)- and (2R)-DOTAP chloride, to a process for the preparation of these modifications, and to the use thereof as constituent for the preparation of medicaments.
Abstract: Claimed is a cyclometallated organometallic light emitting complex having two tridentate ligand portions sharing a central heterocycle “A” providing a binding-site for each of the two metals (formula I): Formula (I): A more illustrative embodiment is formula (XII): Characterizing for the invention is that either one of XI and X2 and either one of Y1 and Y2 is carbon. The dinuclear complexes are for use in OLEDs.
Abstract: The present invention relates to the improvement of organic electroluminescent devices, in particular blue-emitting devices, by using compounds of the formula (1) as dopants in the emitting layer.
Type:
Grant
Filed:
October 2, 2014
Date of Patent:
October 4, 2016
Assignee:
Merck Patent GmbH
Inventors:
Horst Vestweber, Holger Heil, Philipp Stoessel, Arne Buesing, Amir Hossain Parham, Rocco Fortte
Abstract: Compounds of the formula I in which R, X1, X2, X3, X4, R1, R2 and q have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Type:
Application
Filed:
February 24, 2014
Publication date:
September 29, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
Wolfgang STAEHLE, Christos TSAKLAKIDIS, Manja FRIESE-HAMIM, Birgitta LEUTHNER, Dirk WIENKE
Abstract: The invention relates to pharmaceutically important variants of the major allergen Phl p 1 from timothy grass, characterized in that a preparation, hitherto not possible, of monomeric molecules which are soluble and stable in physiological media can be carried out with the aid of prokaryotic expression systems and subsequent purification thereof.
Type:
Grant
Filed:
March 22, 2010
Date of Patent:
September 27, 2016
Assignee:
Merck Patent GmbH
Inventors:
Roland Suck, Helmut Fiebig, Oliver Cromwell
Abstract: The present invention relates to piperidine and pyrazine derivatives according to formulae (Ia), (Ib) and (II) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers.
Type:
Grant
Filed:
July 30, 2014
Date of Patent:
September 27, 2016
Assignee:
MERCK PATENT GMBH
Inventors:
Kai Schiemann, Melanie Schultz, Wolfgang Staehle
Abstract: The invention relates to novel conjugated polymers containing one or more diindeno-thieno[3,2-b]thiophene based polycyclic repeating units, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising these polymers, polymer blends, mixtures or formulations.
Type:
Application
Filed:
September 26, 2014
Publication date:
September 22, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
William MITCHELL, Mansoor D'LAVARI, Changsheng WANG, David SPARROWE
Abstract: Disclosed are novel conjugated polymers containing one or more 3,4-dithia-7-sila-cyclopenta[a]pentalene based units and one or more pyrazino[2,3-g]quinoxaline based units, methods for their preparation and educts or intermediates used therein, polymer blends, mixtures and formulations containing them, the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices containing these polymers, polymer blends, mixtures or formulations.
Type:
Application
Filed:
October 13, 2014
Publication date:
September 22, 2016
Applicant:
MERCK PATENT GMBH
Inventors:
Lana NANSON, Nicolas BLOUIN, Steven TIERNEY
Abstract: The invention relates to a filling device (1) for dispensing a fluid into at least one container, where the filling device (1) has a weighing system (2) and a filling-needle system (3). The weighing system (2) has a positioning device (4) which can be adapted to a container diameter and which may have an annular design. The weighing system (2) is arranged on an accommodation platform (7) which can be moved vertically by means of a linear unit. The filling-needle system (3) is arranged on a displacement unit in a position at a distance in the axial direction above the positioning device (4).
Abstract: The present invention relates to electrically conductive pigments, to a process for the preparation thereof and to the use thereof, in particular in antistatic or dissipative articles or surfaces, for example in paints, coatings, printing inks or floorcoverings.
Abstract: Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect the presence of Der p III nucleic acid in a sample or for the recombinant production of peptides having an activity of Der p III. Peptides having an activity of Der p III can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites.
Type:
Grant
Filed:
January 23, 2009
Date of Patent:
September 20, 2016
Assignee:
MERCK PATENT GMBH
Inventors:
Wayne R. Thomas, Kaw-Yan Chua, Bruce L. Rogers, Mei-chang Kuo
Abstract: [Object] To provide a composition enabling to form a fine negative photoresist pattern free from troubles, such as, surface roughness, bridge defects, and resolution failure; and also to provide a pattern formation method using that composition. [Means to Solve the Problem] A fine pattern-forming composition is used for miniaturizing a resist pattern by fattening said pattern in a process of formation of a negative resist pattern using a chemically amplified resist composition. The fine pattern-forming composition comprises a polymer comprising a repeating unit having a structure of the following formula (A), (B) or (C): and a solvent. This composition is cast on a negative resist pattern obtained by development with an organic solvent developer, and then heated to form a fine pattern.
Abstract: The invention relates to a process of modifying the surface energy of dielectric structures, like for example dielectric layers or bank structures, in organic electronic (OE) devices, more specifically in organic field effect transistors (OFETs).