Abstract: Compounds of the formula I in which R1, R2, R3, X1, X2 and Y have the meanings indicated in claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Abstract: In packaging (1) for a product (3) comprising at least one hygroscopic flowable solid, a drying wrapping (10) made from a moisture-impermeable material which surrounds a product bag (2) filled with the product (3) is arranged in a transport container (4), and in which the desiccant (14) is arranged on an inside (11) of the drying wrapping (10) facing the product bag (2). The desiccant (14) is arranged in at least one, preferably in a plurality of desiccant bags (13). The at least one desiccant bag (13) is covered and fixed by a moisture-permeable perforated covering (16) on the inside (11) of the drying wrapping (10).
Abstract: The present invention relates to compounds according to formula (1) or formula (2) which are suitable for use in electronic devices, more particularly organic electroluminescence devices, and also to electronic devices which contain said compounds.
Type:
Application
Filed:
July 11, 2013
Publication date:
August 27, 2015
Applicant:
Merck Patent GmbH
Inventors:
Elvira Montenegro, Amir H. Parham, Anja Jatsch, Christof Pflumm, Jones V. Kroeber, Thomas Eberle
Abstract: The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (??), which is distinguished by the fact that it has a value for the ratio ?1/?n2 in the range 6-45 with a clearing point of >60° C. and a ?? of ??2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
Abstract: The present invention relates to nanoparticulate hardening accelerators, to preparations prepared therefrom, in particular masterbatches comprising nanoparticles, and to the use thereof in polymer matrices, in particular surface coatings and printing inks of all types, which make extremely high demands of color neutrality and/or transparency.
Type:
Grant
Filed:
August 8, 2005
Date of Patent:
August 25, 2015
Assignee:
MERCK PATENT GMBH
Inventors:
Adalbert Huber, Marc Entenmann, Alfred Hennemann, Matthias Koch
Abstract: This invention relates to colored polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, color electrophoretic displays comprising such particle, and new water-soluble dyes.
Type:
Grant
Filed:
January 29, 2010
Date of Patent:
August 25, 2015
Assignee:
Merck Patent GmbH
Inventors:
Nils Greinert, Louise Diane Farrand, Mark James, Ashley Nathan Smith, Mark John Goulding, Daniel Walker, Safyan Khan, Paul Reynolds, Susan Hawkins, Roy Hughes
Abstract: The present invention relates to novel compounds containing fluorinated end groups, to the use thereof as surface-active substances, and to processes for the preparation of these compounds.
Type:
Grant
Filed:
June 1, 2010
Date of Patent:
August 25, 2015
Assignee:
MERCK PATENT GMBH
Inventors:
Wolfgang Hierse, Eckhard Claus, Jan Krause, Melanie Kleineidam, Steffen Schellenberger, Andreas Bathe
Abstract: The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
August 25, 2015
Assignee:
MERCK PATENT GMBH
Inventors:
Ian Hugh Gilbert, Neil Norcross, Beatriz Baragana Ruibal, Achim Porzelle
Abstract: The invention relates to a preparation process for thin semiconducting inorganic films comprising various metals (Cu/In/Zn/Ga/Sn), selenium and/or sulfur. The process uses molecular precursors comprising metal complexes with oximato ligands. Copper-based chalcopyrites of the I-III-IV2-type are prepared with high purity at low temperatures under ambient conditions. The thin films can be used in photovoltaic panels (solar cells).
Type:
Grant
Filed:
May 31, 2011
Date of Patent:
August 25, 2015
Assignee:
Merck Patent GmbH
Inventors:
Ranjan Deepak Deshmukh, Ralf Kuegler, Joerg J. Schneider, Rudolf Hoffmann
Abstract: The invention relates to a solid pharmaceutical preparation comprising levothyroxine sodium, gelatine, citric acid and a filler. The solid pharmaceutical preparation has an improved stability.
Type:
Application
Filed:
August 1, 2013
Publication date:
August 20, 2015
Applicant:
MERCK PATENT GMBH
Inventors:
Hiltrud Lindenblatt, Thomas T. Frank, Reiner Vonderschmitt
Abstract: The present invention relates to white-emitting organic electroluminescent devices which have at least one blue-fluorescent emitter layer and at least one phosphorescent emitter layer.
Type:
Grant
Filed:
March 10, 2010
Date of Patent:
August 18, 2015
Assignee:
Merck Patent GmbH
Inventors:
Joachim Kaiser, Holger Heil, Simone Leu, Horst Vestweber
Abstract: This invention relates to polymer particles comprising monomer units of at least one reactive mesogen, a process for their preparation, the use of these particles for the preparation of optical, electrooptical, electronic, electrochemical, electrophotographic, electrowetting and electrophoretic displays and/or devices and security, cosmetic, decorative, and diagnostic applications, and electrophoretic fluids and displays.
Type:
Grant
Filed:
May 3, 2012
Date of Patent:
August 18, 2015
Assignee:
Merck Patent GmbH
Inventors:
Laura Ramon-Gimenez, Jonathan Henry Wilson, Owain Llyr Parri, Mark John Goulding, Roger Kemp, Louise Diane Farrand
Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.
Type:
Application
Filed:
February 2, 2015
Publication date:
August 13, 2015
Applicant:
MERCK PATENT GMBH
Inventors:
Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
Abstract: The invention relates to a process of modifying the surface energy of dielectric structures, like for example dielectric layers or bank structures, in organic electronic (OE) devices, more specifically in organic field effect transistors (OFETs).
Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which DDR2 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
Type:
Application
Filed:
July 29, 2013
Publication date:
August 13, 2015
Applicant:
Merck Patent GmbH
Inventors:
Margarita Wucherer-Plietker, Daniela Werkmann, Anne Gigout, Daniel Kuhn, Edgar Sawatzky
Abstract: The invention relates to formulations containing doped conductive polymers, which due to outstanding hole injection characteristics and high conductivity are very suitable for use in organic electronic devices, preferably in organic electroluminescent devices, in particular in the buffer layers thereof. Thus the invention further relates to the use of the formulations according to the invention in organic electronic devices, preferably in electroluminescent devices, in particular in the buffer layers thereof.
Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.
Abstract: The present invention relates to an improved electrodeionization (EDI) module and apparatus adapted to transfer ions present in a liquid under the influence of an electric field.
Abstract: Disclosed are phosphors of formula (I) (Ln1?a?bGdaSmb)wMgxSry(Al1?cBc)zO(3/2w+x+y+3/2z) (I), where Ln=Y, La and/or Lu; a, c=0.0 to 1.0; 0<b<0.2 and a+b<1.0; w=1.0 to 3.0; x, y=1.0 to 2.0 and z>0.0 to 12.0, and to a process for the preparation of these phosphors and to the use thereof as conversion phosphors for conversion of the near-UV emission from an LED.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
August 11, 2015
Assignee:
Merck Patent GmbH
Inventors:
Holger Winkler, Thomas Juestel, Simas Sakirzanovas