Patents Assigned to Merck Patents GmbH
  • LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY
    Publication number: 20150184077
    Abstract: The present invention relates to dielectrically positive liquid-crystalline media comprising one or more compounds of the formula I and/or TINUVIN 770®, in which the parameters have the respective meanings indicated in the specification, and optionally one or more further dielectrically positive compounds and optionally one or more further dielectrically neutral compounds, and to liquid-crystal displays, especially active-matrix displays and in particular TN, IPS and FFS displays, containing these media.
    Type: Application
    Filed: May 21, 2013
    Publication date: July 2, 2015
    Applicant: Merck Patent GmbH
    Inventors: Achim Goetz, Hee-Kyu Lee, Mark Goebel
  • Pyrazolopyridinone derivatives as LPA receptor antagonists
    Patent number: 9067938
    Abstract: The present invention relates to novel pyrazolopyridinone derivatives according to formula (I) and a process of manufacturing thereof. These pyrazolopyridinone derivatives can be used as LPA receptor antagonists for the treatment of various herein disclosed diseases.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: June 30, 2015
    Assignee: Merck Patent GmbH
    Inventors: Kai Schiemann, Wolfgang Staehle, Sr., Dirk Wienke
  • LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20150175884
    Abstract: The invention relates to compounds of the formula I, to a liquid-crystalline medium which comprises at least one compound of the formula I, in which R1, R1*, L1, L2, L3 and L4 have the meanings indicated herein, and to the use thereof for an active-matrix display, in particular based on the VA, PSA, PS-VA, PM-VA, PALC, IPS, PS-IPS, SA-VA, SS-VA, FFS or PS-FFS effect.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 25, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Harald HIRSCHMANN, Monika BAUER, Martina WINDHORST, Marcus REUTER, Volker REIFFENRATH, Matthias BREMER
  • Bimesogenic Compounds and Mesogenic Media
    Publication number: 20150175883
    Abstract: The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula I in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 25, 2015
    Applicant: Merck Patent GmbH
    Inventors: Kevin Adlem, Owain Llyr Parri, Rachel Tuffin, Patricia Eileen Saxton, Mariam Namutebi, Benjamin Snow
  • Ligands And Their Preparation
    Publication number: 20150175574
    Abstract: The present invention relates to secondary amines suitable for the preparation of ligands for organometallic complexes, their preparation and their use.
    Type: Application
    Filed: June 27, 2013
    Publication date: June 25, 2015
    Applicant: Merck Patent GmbH
    Inventors: Rémi Manouk Anémian, Jong-Hyub Paek
  • MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY
    Publication number: 20150175886
    Abstract: The invention relates to mesogenic media comprising a first component, component A, consisting of bimesogenic compounds selected from the group of compounds of formulae A-I to A-III a second component, component B, consisting of nematogenic compounds, preferably selected from the group of compounds of formulae B-I to B-III and a third component, component C, consisting of one or more chiral molecules, wherein the parameters have the meaning given in claim 1, to the use of mesogenic media in flexoelectric liquid crystal devices and to those devices comprising a liquid crystal medium according to the present invention.
    Type: Application
    Filed: May 10, 2013
    Publication date: June 25, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Rachel Tuffin, Benjamin Snow, Owain Llyr Parri, Simon Siemianowski, Rebecca Proctor, Kevin Adlem
  • IMIDAZO-OXADIAZOLE AND IMIDAZO-THIADIAZOLE DERIVATIVES
    Publication number: 20150175628
    Abstract: The present invention provides compounds of Formula (I) used as Amyloid beta lowering agent for the treatment of neurodegenerative diseases.
    Type: Application
    Filed: May 23, 2013
    Publication date: June 25, 2015
    Applicant: Merck Patent GmbH
    Inventors: Anna Quattropani, Dominique Swinnen
  • Inhibitors of sphingosine kinase
    Patent number: 9062015
    Abstract: The present invention relates to compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, M1, M2, M3, M4, Y1, Y2, V, W, n, m and o have the meanings given in Claim 1, and physiologically acceptable salts, derivatives, prodrugs, solvates, tautomers and stereoisomers thereof, including mixtures thereof in all ratios, for use in the treatment of diseases which are influenced by inhibition of Sph kinase 1.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: June 23, 2015
    Assignee: Merck Patent GmbH
    Inventors: Frank Stieber, Dirk Wienke
  • Low temperature synthesis of nanowires in solution
    Patent number: 9064701
    Abstract: Methods synthesizing nanowires in solution at low temperatures (e.g., about 400° C. or lower) are provided. In the present methods, the nanowires are synthesized by exposing nanowire precursors to metal nanocrystals in a nanowire growth solution comprising a solvent. The metal nanocrystals serve as seed particles that catalyze the growth of the semiconductor nanowires. The metal nanocrystals may be formed in situ in the growth solution from metal nanocrystal precursors. Alternatively, the nanowires may be pre-formed and added to the growth solution.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: June 23, 2015
    Assignee: Merck Patent GmbH
    Inventors: Dayne D. Fanfair, Brian A. Korgel
  • Pyrimidinyl pyridazinone derivatives
    Patent number: 9062029
    Abstract: Compounds selected from the group according to Claim 1 are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: June 23, 2015
    Assignee: Merck Patent GmbH
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • Organic electronic device
    Patent number: 9066410
    Abstract: The present invention relates to organic electroluminescent devices which comprise aromatic nitrogen heterocyclic compounds, in particular in a hole-injection layer and/or in a hole-blocking layer and/or in an electron-transport layer and/or in an emitting layer.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: June 23, 2015
    Assignee: Merck Patent GmbH
    Inventor: Esther Breuning
  • Metal Complexes
    Publication number: 20150171348
    Abstract: The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.
    Type: Application
    Filed: July 2, 2013
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Dominik Joosten, Esther Breuning, Joachim Kaiser
  • PROCESS FOR PRODUCING CELL CULTURE MEDIA
    Publication number: 20150166949
    Abstract: The present invention relates to an a process for manufacturing dry powder cell culture media. The preparation and usage of mixed particles generated by co-lyophilisation leads to homogenously blended cell culture media.
    Type: Application
    Filed: May 17, 2013
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventor: Joerg Von Hagen
  • LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20150166890
    Abstract: The invention relates to the compounds of the formula I and to a liquid-crystalline medium based on a mixture of polar compounds which contains at least one compound of the formula I in which R1, ring A1, L1, L2, L3, L4, L5, L6, L7, L8, Z1 and m have the meanings indicated in claim 1 and to the use of the LC mixtures in electro-optical displays, especially for the self-aligning VA mode.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventors: Graziano Archetti, Izumi Saito, Rocco Fortte, Timo Uebel
  • EFFECT PIGMENTS
    Publication number: 20150166799
    Abstract: The present invention relates to effect pigments based on coated, flake-form substrates, where an organic coating which contains fluoroalkyl groups and hydrophilic groups and is built up from at least one siloxane and/or at least one silane is applied to the substrate as outer layer.
    Type: Application
    Filed: July 5, 2013
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventors: Ulrich Schoenefeld, Joachim Duschek, Alfred Hennemann
  • METHOD OF PREPARING A BIREFRINGENT POLYMER FILM
    Publication number: 20150166892
    Abstract: The invention relates to a method of preparing a polymer film and to the use of such polymer film as in liquid crystal displays (LCDs) or other optical or electrooptical devices, for decorative or security applications, as alignment layer or optical retardation film.
    Type: Application
    Filed: May 24, 2013
    Publication date: June 18, 2015
    Applicant: Merck Patent GmbH
    Inventors: Iain Gardiner, Owain Llyr Parri, Tara Perrett, Joseph Sargent, Jack Bradford, Sarah Whitehouse
  • Process for the preparation of phosphinic acid esters
    Patent number: 9056881
    Abstract: The invention relates to a process for the preparation of alkyl phosphinates, alkenyl phosphinates, alkynyl phosphinates or phenyl phosphinates by reaction of a corresponding phosphine oxide with an alcohol or phenol in the presence of alkali-metal fluoride or tetraalkylammonium fluoride.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: June 16, 2015
    Assignee: Merck Patent GmbH
    Inventors: Nikolai Mykola Ignatyev, Michael Schulte, Christoph Alexander Jablonka, Karsten Koppe, Walter Frank
  • COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20150159088
    Abstract: The invention relates to compounds of the formula I, and to a liquid-crystalline medium, preferably having a nematic phase and negative dielectric anisotropy, which comprises one or more compounds of formula I, defined herein, for use in an electro-optical display, particularly in an active-matrix display based on the VA, ECB, PALC, FFS or IPS effect, and to the use of the compounds of the formula I for the stabilization of a liquid-crystalline medium which comprises one or more compounds of the formula II and one or more compounds of the formulae III-1 to III-4, defined herein.
    Type: Application
    Filed: February 20, 2015
    Publication date: June 11, 2015
    Applicant: Merck Patent GmbH
    Inventors: Mark GOEBEL, Rocco FORTTE, Detlef PAULUTH
  • Microsphere comprising a polymer core, a shell and an absorber
    Patent number: 9050843
    Abstract: The present invention relates to Microsphere comprising a core and a shell, in which the core comprises a polymer and at least two laser light absorber. The particle size of the microsphere is for example between 50 nm and 50 micron and preferably between 100 nm and 10 micron. The core comprises a thermoplastic polymer, the shell comprises a compatibilizer. The laser light absorbers are chosen from oxides, hydroxides, sulphides, sulphates and phosphates of metals such as copper, bismuth, tin, aluminum, zinc, silver, titanium, antimony, manganese, iron, nickel, barium, gallium, germanium, arsenic and chromium and combinations of two or more of these metals, laser light absorbing (in)organic dyes or metaloxide coated flakes. The invention further relates to the use of the microsphere as a laser marking additive and to a process for the production of the microsphere by reactive extrusion.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: June 9, 2015
    Assignee: Merck Patent GmbH
    Inventors: Franciscus Gerardus Henricus Duijnhoven Van, Franciscus Wilhelmus Maria Gelissen
  • Pyrido [2, 3-B] pyrazine compounds and their therapeutical uses such as for inhibiting ATP consuming proteins and treating diseases associated therewith
    Patent number: 9051318
    Abstract: The present invention relates to novel pyrido[2,3-b]pyrazine compounds of formula (I): and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: June 9, 2015
    Assignee: Merck Patent GmbH
    Inventors: Dieter Dorsch, Alfred Jonczyk, Guenter Hoelzemann, Christiane Amendt, Frank Zenke