Patents Assigned to Merck Patents GmbH
  • TREATMENT REGIMEN FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
    Publication number: 20240374715
    Abstract: A novel treatment regimen is provided for the treatment of autoimmune disorders. Said novel treatment regimen provides for an efficacious treatment of autoimmune disorders with an advantageous safety profile and/or a high quality of life for the patient. Said novel treatment regimen provides for an advantageous benefit-risk ratio for patients endangered by the risk of infections.
    Type: Application
    Filed: March 8, 2024
    Publication date: November 14, 2024
    Applicant: Merck Patent GmbH
    Inventors: Ursula BOSCHERT, Urs Wiedemann
  • ELECTRONIC ELEMENT COMPRISING A PLURALITY OF CELLS ARRANGED IN A THREE DIMENSIONAL ARRAY OF CELLS AND METHOD FOR PRODUCING SUCH AN ELECTRONIC DEVICE
    Publication number: 20240381674
    Abstract: An electronic element (10) comprising a plurality of cells (100) arranged in a three dimensional array of cells (100) is provided, wherein the cells (100) are located at crossings between two crossed electrode lines (30, 31). Each cell (100) of the electronic component (100) comprises in this order a first electrode (102), a part (104) of a molecular layer (20) and a second electrode (106), wherein the molecular layer (20) is a self-assembled monolayer of organic molecules having an anchoring group connected to a dipolar unit by means of a conformationally flexible unit. Further aspects of the invention relate to a method and a compound for producing such an electronic element (10) and the use of such an electronic element (10).
    Type: Application
    Filed: June 7, 2022
    Publication date: November 14, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Peer KIRSCH, Sebastian RESCH, Henning SEIM, Marc TORNOW
  • Materials for organic electroluminescent devices
    Patent number: 12139500
    Abstract: The present invention relates to a compound of the formula (1), to the use of the compound in an electronic device, and to an electronic device comprising a compound of the formula (1). The present invention furthermore relates to a process for the preparation of a compound of the formula (1) and to a formulation comprising one or more compounds of the formula (1).
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: November 12, 2024
    Assignee: Merck Patent GmbH
    Inventors: Jens Engelhart, Philipp Stoessel, Christian Ehrenreich, Christian Eickhoff, Philipp Harbach, Amir Parham
  • LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20240368471
    Abstract: Liquid-crystalline (LC) media having positive dielectric anisotropy and liquid-crystal displays (LCDs) containing these media, especially displays addressed by an active matrix and in particular to LC displays of the TN, PS-TN, STN, TN-TFT, OCB, IPS, PS-IPS, FFS, HB-FFS, XB-FFS, PS-FFS, SA-HB-FFS, SA-XB-FFS, polymer stabilised SA-HB-FFS, polymer stabilised SA-XB-FFS, positive VA or positive PS-VA type.
    Type: Application
    Filed: June 25, 2024
    Publication date: November 7, 2024
    Applicant: Merck Patent GmbH
    Inventors: Sven Christian LAUT, Sabrina PFEIFFER, Philipp Hans FACKLER
  • Liquid crystal-based light valve
    Patent number: 12134725
    Abstract: A light valve that is operable in and electrically switchable between an optically clear and transparent state and an opaque state, wherein one or more polymerisable mesogenic compounds provided in a layer containing a liquid-crystalline medium that comprises one or more mesogenic compounds, one or more chiral compounds, one or more dichroic dyes and the one or more polymerisable mesogenic compounds are subjected to photopolymerisation. Further, a liquid-crystalline medium used in the method, a light valve obtained or respectively obtainable by carrying out the method, and the use of the light valve in mobile devices.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: November 5, 2024
    Assignee: Merck Patent GmbH
    Inventors: Christian Schoenefeld, Michael Junge, Mark Goebel, Raphael Lisicki, Kevin Kaiser
  • LIQUID CRYSTAL MEDIUM
    Publication number: 20240360362
    Abstract: Liquid crystal (LC) media having negative dielectric anisotropy, the use thereof in an electro-optical display, particularly in a display with passive matrix addressing, based on the VA, ECB, FFS or IPS effect, and displays of this type, in particular an energy saving PM-VA display with low duty driving.
    Type: Application
    Filed: April 10, 2023
    Publication date: October 31, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Akihiro KOJIMA, Fumio SHIMANO
  • MMP13 binding immunoglobulins
    Patent number: 12129308
    Abstract: The present invention relates to immunoglobulins that specifically bind MMP13 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit an activity of MMP13 and preferably are also stable.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: October 29, 2024
    Assignees: MERCK PATENT GMBH, ABLYNX NV
    Inventors: Francis Descamps, Gerald Beste, Guy Hermans, Hans Guehring, Lars Toleikis, Christoph Ladel
  • METHOD FOR REDUCING ENDOTOXIN LEVELS IN NUCLEIC ACID PURIFICATION
    Publication number: 20240352441
    Abstract: The present invention relates to a method for reducing endotoxin levels or removing endotoxins from nucleic acids. For this a non-ionic detergent selected from the group of alkylglycosides and secondary alcohol alkoxylates or mixtures thereof is added prior or during anion exchange chromatographic purification of the nucleic acids using a membrane or monolith-based sorbent.
    Type: Application
    Filed: August 3, 2022
    Publication date: October 24, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Anja HEINEN-KREUZIG, Andre KIESEWETTER, Andreas STEIN, Akshat GUPTA
  • METHOD FOR PRODUCING SILICA PARTICLES, SILICA PARTICLES PRODUCED BY SUCH METHOD, COMPOSITIONS AND USES OF SUCH SILICA PARTICLES
    Publication number: 20240351889
    Abstract: The present application relates to a method for producing silica particles, and to the silica particles produced by such method. The present application further relates to compositions comprising the silica particles produced by such method as well as to uses of such silica particles and compositions comprising such silica particles.
    Type: Application
    Filed: August 10, 2022
    Publication date: October 24, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Eric JACQUINOT, Leo HANUS, Geary GRAHAM
  • Negative resist formulation for producing undercut pattern profiles
    Patent number: 12124166
    Abstract: A negative-acting, photoresist composition, imageable by 365 nm radiation that is developable in aqueous base. Apart from solvent, this composition comprises: a) an aqueous base soluble phenolic film-forming polymeric binder resin having ring bonded hydroxyl groups; b) a photoacid generator c) a crosslinking agent which comprises an etherified melamine; d) a dye as described herein; e) a quencher system consisting essentially of an amine quencher, or a mixture of such amine quenchers, as described. This invention also pertains to processes of using this composition as a photoresist.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: October 22, 2024
    Assignee: Merck Patent GmbH
    Inventors: Anupama Mukherjee, Medhat A. Toukhy
  • Smart consumables/identifier label and antenna for smart consumables/identifier label
    Patent number: 12118420
    Abstract: Described herein is a label 1 for marking containers or equipment by adhering the label to a surface thereof. The label 1 includes a support material base 11, at least one RFID microelectronic device 5c included in the support material base 11, and a plurality of antennas 5a,5b for different frequency ranges connected with the at least one RFID microelectronic device 5c and included in the support material base 11. The plurality of antennas 5a, 5b include a first antenna 5a for the frequency range of 860 to 960 MHz and having a theoretical read range peak of more than 4 m when provided on a glass surface, and the label has a dimension of 40 mm*20 mm or less.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: October 15, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Christian-Hubertus Kuechenthal, Roja Azees, Dan Kvelstad, Sven Erfurth
  • Liquid crystal medium
    Patent number: 12116521
    Abstract: The present invention relates to a liquid crystal (LC) medium comprising a compound of formula I and one or more compounds of formula II as defined in claim 1, and to the use thereof for optical, electro-optical and electronic purposes, in particular in LC displays, especially in IPS, FFS, VA or PS-VA displays.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: October 15, 2024
    Assignee: MERCK PATENT GMBH
    Inventor: Sven Christian Laut
  • NOVEL TREATMENT REGIMEN FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
    Publication number: 20240335529
    Abstract: A novel treatment regimen is provided for the treatment of autoimmune disorders. Said novel treatment regimen provides for an efficacious treatment of autoimmune disorders with an advantageous safety profile and/or a high quality of life for the patient. Said novel treatment regimen provides for an advantageous benefit-risk ratio for patients endangered by the risk of infections.
    Type: Application
    Filed: June 20, 2024
    Publication date: October 10, 2024
    Applicant: Merck Patent GmbH
    Inventors: Ursula Boschert, Urs Wiedemann
  • Liquid-crystal medium
    Patent number: 12104109
    Abstract: A liquid-crystal (LC) material having negative dielectric anisotropy and the use thereof for optical, electro-optical and electronic purposes, such as for example in LC displays, in particular energy saving displays based on the ECB, IPS or FFS effect, where the liquid crystal medium contains one or more compounds of formula I and one or more compounds compounds of formulae IIA, IIB, IIC and IID
    Type: Grant
    Filed: June 22, 2023
    Date of Patent: October 1, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Chi-Shun Huang, Sven Christian Laut, Hee-Kyu Lee, Minghui Yang, Harald Hirschmann, Kuang-Ting Chou, Shih-Chieh Hung, Alexander Hahn, Philipp Wucher
  • Tricyclic heterocycles
    Publication number: 20240317753
    Abstract: Tricyclic heterocycles are disclosed. These heterocyclic compounds are useful as TEAD binders and/or inhibitors of YAP-TEAD and TAZ-TEAD protein-protein interaction or binding and for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases, in particular cancer.
    Type: Application
    Filed: May 5, 2021
    Publication date: September 26, 2024
    Applicants: Merck Patent GmbH, Cancer Research Technology Ltd.
    Inventors: Timo HEINRICH, Sarah Schlesiger, Jakub Gunera, Emma Carswell, Lisa Koetzner, Andreas Blum
  • Rinse and method of use thereof for removing edge protection layers and residual metal hardmask components
    Patent number: 12099305
    Abstract: The disclosed subject matter relates to a rinse and methods of use thereof for removing an edge protection layer and residual hardmask components (e.g., metals) from the edge and at least one proximate surface of a wafer/substrate where the rinse includes acetic acid and/or a halogenated acetic acid of structure (A) wherein R1 and R2 are independently hydrogen or a halogen and R3 is a halogen and (ii) a compound having structure (B) wherein each of Ra, Rb, Rc, Rd, Re, Rf, Rg and Rh may independently be hydrogen, a substituted or an unsubstituted alkyl group, a substituted or an unsubstituted halogenated alkyl group, a substituted or an unsubstituted alkyl carbonyl group, a halogen, and a hydroxy group.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: September 24, 2024
    Assignee: Merck Patent GmbH
    Inventors: M. Dalil Rahman, Salem Mullen, JoonYeon Cho
  • Mixing device
    Patent number: 12083486
    Abstract: A mixing device (1) for cyclically imparting a force on an external surface (A) of a bag (B) for agitating a content (C) of the bag (B), the mixing device (1) comprising a lever (2) supported so as to be able to pivot about a pivot (3), a weight (4) provided on a first side of the lever (2), a driver (5) arranged to cooperate with the lever (2), a motor (6) for moving the driver (5) to lift the first side of the lever (2) with the weight (4) against gravity and to drop the first side against the external surface (A) of the bag (B), and a holder (7) for supporting the mixing device (1) such that the first side of the lever (2) can contact the external surface (A) of the bag (B) in the drop motion.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: September 10, 2024
    Assignee: Merck Patent GmbH
    Inventors: Stephane Olivier, Gaetan Bour
  • GCN2 inhibitors and uses thereof
    Patent number: 12084438
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: September 10, 2024
    Assignees: Merck Patent GmbH, Vertex Pharmaceuticals Incorporated
    Inventors: Matthew Bleich, Jean-Damien Charrier, Huijun Dong, Steven Durrant, Meredith Suzanne Eno, Gorka Etxebarria I Jardi, Simon Everitt, Damien Fraysse, Ronald Knegtel, Igor Mochalkin, Kiri North, Filippos Porichis, Hui Qiu, Robert Pullin, Pierre-Henri Storck, Heather Clare Twin, Yufang Xiao
  • Heteroaromatic isothiocyanates
    Patent number: 12077703
    Abstract: The present invention relates to heteroaromatic isothiocyanates of formula N as defined in claim 1, to liquid-crystalline media comprising one or more compounds of formula N and to high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, e.g. phased array antennas.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: September 3, 2024
    Assignee: MERCK PATENT GMBH
    Inventors: Amir Hossain Parham, Constanze Brocke, Carsten Fritzsch, Dagmar Klass
  • Compounds for electronic devices
    Patent number: 12077541
    Abstract: The present application relates to an amine compound according to formula (I), (II) or (III) which is suitable for use in electronic devices.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: September 3, 2024
    Assignee: Merck Patent GmbH
    Inventors: Ilona Stengel, Florian Maier-Flaig, Philipp Harbach, Elvira Montenegro, Aurélie Ludemann