Abstract: The present invention describes dibenzofuran derivatives substituted by electron-deficient heteroaryl groups, and electronic devices, especially organic electroluminescent devices, comprising these compounds as triplet matrix materials.

Abstract: Crystalline monosodium salt of 5-methyl-(6S)-tetrahydrofolic acid wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to sodium is from 1:0.5 to 1:1.5 (in mol/mol) and/or hydrates and/or solvates thereof, their use as pharmaceuticals, as well as processes of obtaining the same.

Abstract: A liquid crystal medium comprising one or more compounds of formula PT and one or more compounds of formula GF and/or UI in which the occurring groups and parameters have the meanings defined in claim 1. Also, high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, e.g. phased array antennas.

Abstract: Method for selecting at least one viscosity changing excipient for a formulation containing at least one unknown protein via a computer includes providing a data set that describes the viscosity of several known formulations containing at least one protein and optionally at least one viscosity changing excipient; generating representations of at least one excipient; using a Machine Learning Model executed on the computer to recognize patterns in the data set to evaluate the viscosity changing effect of the viscosity changing excipient to a new formulation containing at least one unknown protein by applying the recognized patterns on provided data of the unknown protein; selecting the at least one excipient according to an acquisition criterion and applying the excipient to the unknown protein, wherein the provided data of the at least one unknown protein describe the viscosity of a protein composition containing the at least one unknown protein.

Abstract: Liquid-crystalline (LC) media having positive dielectric anisotropy and liquid-crystal displays (LCDs) containing these media, especially displays addressed by an active matrix and in particular to LC displays of the TN, PS-TN, STN, TN-TFT, OCB, IPS, PS-IPS, FFS, HB-FFS, XB-FFS, PS-FFS, SA-HB-FFS, SA-XB-FFS, polymer stabilised SA-HB-FFS, polymer stabilised SA-XB-FFS, positive VA or positive PS-VA type.

Abstract: A method of manufacturing a composition with improved quantum yield, containing at least these steps: a/ manufacturing a mixture by at least these steps: 1/ providing a semiconducting light emitting nanoparticle, 2/ adding a macromolecular compound comprising at least an anchoring group; 3/ adding an organic additive, and b/ subjecting the mixture from step a/ to irradiation with light of a wavelength in the range of 300 to 600 nm having an intensity in the range of 0.025 to 1 W/cm2 to obtain the composition; wherein the organic additive is defined by formula (Ia): M-(X—Y)2, wherein M is a divalent metal ion, X is a hydrocarbon chain, and Y is a functional group.

Abstract: A two-bit memory device having a layer structure containing in order a bottom layer, a molecular layer containing a chiral compound having at least one polar functional group, and a top layer, which is electrically conductive and ferromagnetic. The chiral compound acts as a spin filter for electrons passing through the molecular layer. The chiral compound is of flexible conformation and has a conformation-flexible molecular dipole moment. An electrical resistance of the layer structure for an electrical current running from the bottom layer to the top layer has at least four distinct states which depend on the magnetization of the top layer and on the orientation of the conformation-flexible dipole moment of the chiral compound. Furthermore, a method for operating the two-bit memory device and an electronic component containing at least one two-bit memory device.

Abstract: The present invention relates to a liquid crystalline medium comprising dichroitic dyes made of benzothiadiazoles and related extended heterocyclic derivatives, the use of said medium for optical, electro-optical and electronic purposes, in particular in devices for regulating the passage of radiation energy from an outside space into an inside space, for example in windows. The invention further relates to devices containing the liquid crystalline medium according to the invention. Some new dichroitic dyes are disclosed.

Abstract: A novel treatment regimen is provided for the treatment of autoimmune disorders. Said novel treatment regimen provides for an efficacious treatment of autoimmune disorders with an advantageous safety profile and/or a high quality of life for the patient. Said novel treatment regimen provides for an advantageous benefit-risk ratio for patients endangered by the risk of infections.

Abstract: The invention relates to EGFR targeting Fc antigen binding fragment-drug conjugates (EGFR Fcab-drug conjugates) and the use of the EGFR Fcab-drug conjugates of the present invention for the treatment and/or prevention of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such EGFR Fcab-drug conjugates. Further, the invention relates to EGFR Fcab-label conjugates and diagnostic compositions containing such EGFR Fcab-label conjugates.

Abstract: Liquid-crystalline (LC) media having positive dielectric anisotropy and liquid-crystal displays (LCDs) containing these media, especially displays addressed by an active matrix and in particular energy saving LC displays of the TN, PS-TN, STN, TN-TFT, OCB, IPS, PS-IPS, FFS, HB-FFS, XB-FFS, PS-FFS, SA-HB-FFS, SA-XB-FFS, polymer stabilised SA-HB-FFS, polymer stabilised SA-XB-FFS, positive VA or positive PS-VA type. The media have an improved long-term stability against UV radiation and elevated temperatures.

Abstract: The invention relates to compounds of formula (1) which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing said compounds. X is, identically or differently in each occurrence, CR or N, or two adjacent X stand for a group of the following formula (2), wherein the dashed bonds mark the bonding of said group in formula (1), with the stipulation that the compound of formula (1) contains one or two groups of formula (2); X1 is, identically or differently in each occurrence, CR or N; Y is, identically or differently in each occurrence, CR or N; Z1, Z2, Z3 are, identically or differently in each occurrence, O, S, N—Ar or CR2.

Abstract: The invention relates to a polymerisable LC medium with flat, negative or positive optical dispersion, a polymer film with flat, negative or positive optical dispersion obtainable from such a material, and the use of the polymerisable LC medium and polymer film in optical, electro optical, electronic, semiconducting or luminescent components or devices.

Abstract: A method for controlling the state of two or more liquid crystal-based switchable elements is proposed, wherein the switchable elements are configured as smart windows and/or as switchable subunits of smart windows, wherein in a first step a), at least two keyframes are defined, wherein each keyframe comprises setting values defining the intended state of a group of switchable elements. In a subsequent step b), a display frame is computed, wherein the display frame comprises setting values for the state of the group of switchable elements based on at least one of the defined keyframes. In a subsequent step c), the state of each of the switchable elements of the group of switchable elements is set as defined by the setting values of the computed display frame. Also, a master controller for use with the method, and a system implementing the method.

Abstract: The invention relates to a process for the production of an electronic component comprising a self-assembled monolayer (SAM) using compounds of the formula I R1-(A1-Z1)r—(B1)n—(Z2-A2)s-Sp-G??(I) in which the groups occurring have the meanings defined in Claim 1; the present invention furthermore relates to the use of the components in electronic switching elements and to compounds for the production of the SAM.

Abstract: The present invention describes diazadibenzofuran or diazadibenzothiophene derivatives substituted by carbazole, fluorene, phenanthrene, benzofuran and/or benzothiophene groups, especially for use in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.

Abstract: The present invention relates to a switching layer based on a liquid-crystalline mixture for use in an optical switching element. The invention also encompasses a switching element comprising the switching layer and a window element containing the switching element. The liquid crystalline mixture comprises a low-molecular liquid crystal component, a polymer component and a self-alignment additive for vertical alignment.

Abstract: The invention concerns a RFID label for marking containers or equipment, preferably in a laboratory environment and including in particular cylindrical bottles, vials, syringes, etc., by adhering the RFID layer to a surface thereof. The RFID label has a flat flexible support material base (11), at least one RFID microelectronic device (5c) included in the flat support material base (11), and at least one antenna (5a,5b) connected with the at least one RFID microelectronic device (5c) and included in the flat support material base (11). The flat support material base (11) has a number of predefined cuts (8) distributed about its outer periphery and/or the at least one RFID microelectronic device (5c) includes a tamper detection function and a conductive loop (5d) connected with tamper detection function terminals of the RFID microelectronic device (5c) is included in the flat support material base (11).

Abstract: The present invention is directed towards isomerically pure 18F-labelled (6S)- or (6R)-5-methyltetrahydrofolate radiopharmaceuticals, wherein the phenyl group within the folate structure, has been replaced by an 18F-labelled N-heterocycle, for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof.

Abstract: A polymerisable oligomeric liquid crystal (LC) and a polymerisable LC medium comprising the polymerisable oligomeric LC together with one or more mono-, di- or multireactive mesogenic compounds. Furthermore, a method for the preparation of the oligomeric LC, a birefringent polymer film obtainable from the polymerisable LC medium, and a method of preparation of such a polymer film. Also, the use of the polymer film as optical component, in particular as ultra-thin polariser (UTP) in a liquid crystal display (LCD), for contrast enhancement in an organic light emitting device (OLED), or for AR/AV/VR applications.