Patents Assigned to Merck Patents GmbH
  • Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone
    Patent number: 10464923
    Abstract: The present invention relates to a solid form of 1-(4-{[6-Amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone, or pharmaceutically acceptable salts thereof, useful as BTK inhibitors.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: November 5, 2019
    Assignee: Merck Patent GmbH
    Inventors: Axel Becker, Marco Poma, Edoardo Burini, Christoph Saal, Vedad Theuerkorn
  • Liquid-crystalline medium
    Patent number: 10465114
    Abstract: A liquid-crystalline medium which is suitable for use in a guest-host system. An LC device, preferably a device for the regulation of the passage of energy, containing the liquid-crystalline medium.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: November 5, 2019
    Assignee: MERCK PATENT GMBH
    Inventors: Michael Junge, Andreas Beyer, Ursula Patwal, Peer Kirsch, Susann Beck
  • ALPHA-ALUMINA FLAKES
    Publication number: 20190330475
    Abstract: The present invention relates to alumina flakes having a defined thickness and particle size distribution and to their use in varnishes, paints, automotive coatings printing inks, masterbatches, plastics and cosmetic formulations and as substrate for effect pigments. and organic dyes.
    Type: Application
    Filed: July 2, 2019
    Publication date: October 31, 2019
    Applicant: Merck Patent GmbH
    Inventors: Ryuta SUZUKI, Gerhard PFAFF, Sabine SCHOEN, Fumiko SASAKI, Satoru KOBAYASHI, Koshiro KUNII, Yuji TAKENAKA, Katsuhisa NITTA
  • LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20190330530
    Abstract: The present invention relates to liquid-crystalline media comprising one or more compounds of formula DFS in which the groups and parameters occurring have the meanings indicated in claim 1, to high-frequency components comprising same, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, in particular for microwave phased-array antennas. The present invention further relates to novel mesogenic compounds.
    Type: Application
    Filed: October 23, 2017
    Publication date: October 31, 2019
    Applicant: Merck Patent GmbH
    Inventors: Atsutaka MANABE, Christian JASPER, Volker REIFFENRATH, Constanze BROCKE, Detlef PAULUTH, Dagmar KLASS, Michael WITTEK, Renate SEEGER, Dmitry USHAKOV, Beate SCHNEIDER
  • RE-LOADABLE AUTO INJECTOR
    Publication number: 20190328970
    Abstract: A reloadable auto injector wherein a syringe assembly is movably positioned between a first position in which the needle is accommodated inside a housing and a second position in which the needle protrudes outside the housing. The assembly comprises a syringe, a plunger rod and a plunger rod driver configured to apply a force to the plunger rod to advance the plunger rod in the syringe for delivering at least one dose of medicament. A syringe driver is configured to apply a force to the assembly thereby moving the assembly from the first position to the second position. A reload handle may be connected to the assembly so that user operation of the reload handle retracts the assembly to the first position and simultaneously reload the syringe driver to thereby ready the auto injector for delivering a further dose of medicament. The plunger rod driver is not re-activated.
    Type: Application
    Filed: May 15, 2019
    Publication date: October 31, 2019
    Applicant: Merck Patent GmbH
    Inventors: Soeren BECHMANN, Flemming MADSEN, Esben W. JOHANSEN
  • Dosing Regimen of Avelumab for the Treatment of Cancer
    Publication number: 20190330352
    Abstract: The present invention relates to dosing regimen of avelumab for the treatment of cancer. In particular, the invention relates to improved dosing regimen of avelumab for the treatment of cancer.
    Type: Application
    Filed: October 5, 2017
    Publication date: October 31, 2019
    Applicants: PFIZER INC, MERCK PATENT GmbH
    Inventors: Glen Ian Andrews, Carlo Leonel BELLO, Satjit Singh BRAR, Shaonan WANG, Pascal GIRARD
  • ?-alumina flakes
    Patent number: 10457812
    Abstract: Alpha-Alumina flakes having a particle thickness of 550-1000 nm, a D50-value of 15-30 ?m, a D90-value of 30-45 ?m and a D10-value of ?9.0 ?m. Use of the alumina flakes in varnishes, paints, automotive coatings printing inks, masterbatches, plastics and cosmetic formulations. Also, use of the alumina flakes as a substrate for effect pigments and in organic dyes.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: October 29, 2019
    Assignee: Merck Patent GmbH
    Inventors: Ryuta Suzuki, Gerhard Pfaff, Sabine Schoen, Fumiko Sasaki, Satoru Kobayashi, Koshiro Kunii, Yuji Takenaka, Katsuhisa Nitta
  • Robust antibody purification
    Patent number: 10457720
    Abstract: The present invention refers to a method for the separation of host cell proteins (HCPs), antibody fragments and low molecular weight substances from solutions containing antibodies.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: October 29, 2019
    Assignee: Merck Patent GmbH
    Inventors: Romas Skudas, Matthias Joehnck, Bianca Edelmann, Simon Braun, Mikhail Kozlov, Matthew T. Stone, Kevin Galipeau
  • Imidazolonylquinolines and the use thereof as ATM kinase inhibitors
    Patent number: 10457677
    Abstract: Compounds of the formula (I), which are ATM kinase inhibitors and can be employed, inter alia, for the treatment of cancer.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: October 29, 2019
    Assignee: Merck Patent GmbH
    Inventors: Thomas Fuchss, Kai Schiemann
  • Compounds for optically active devices
    Patent number: 10457658
    Abstract: The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: October 29, 2019
    Assignee: Merck Patent GmbH
    Inventors: Lars Dobelmann-Mara, Stefan Riedmueller, Martin Schraub
  • Compounds and liquid-crystalline medium
    Patent number: 10457871
    Abstract: Compounds of formula I, in which X1, X2, Sp, and R are as defined herein, are suitable for use in liquid-crystal media, such as liquid-crystal media used in liquid-crystal displays.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: October 29, 2019
    Assignee: MERCK PATENT GMBH
    Inventors: Achim Goetz, Rocco Fortte, Martin Engel, Sabrina Maag, Ingo Almeroth, Thomas Mergner, Thorsten Kodek, Detlef Pauluth
  • ALPHA-ALUMINA FLAKES
    Publication number: 20190322871
    Abstract: The present invention relates to alumina flakes having a defined thickness and particle size distribution and to their use in varnishes, paints, automotive coatings printing inks, masterbatches, plastics and cosmetic formulations and as substrate for effect pigments. and organic dyes.
    Type: Application
    Filed: July 2, 2019
    Publication date: October 24, 2019
    Applicant: Merck Patent GmbH
    Inventors: Ryuta SUZUKI, Gerhard PFAFF, Sabine SCHOEN, Fumiko SASAKI, Satoru KOBAYASHI, Koshiro KUNII, Yuji TAKENAKA, Katsuhisa NITTA
  • MATERIALS FOR ELECTRONIC DEVICES
    Publication number: 20190322796
    Abstract: The present application relates to a polymer containing at least one structural unit of a formula (I) and at least one further structural unit selected from structural units A, B and C. The present application further relates to the use of the polymer in an electronic device and to a process for preparing the polymer. The present application further relates to an electronic device comprising the polymer.
    Type: Application
    Filed: December 19, 2017
    Publication date: October 24, 2019
    Applicant: Merck Patent GmbH
    Inventors: Beate Burkhart, Katja Maria Scheible, Nils Koenen, Holger Heil
  • FLUORINE CONTAINING POLYMERS
    Publication number: 20190322776
    Abstract: The present invention relates to novel fluorine containing polymers, compositions comprising the polymers, the use of the polymers in coatings, especially in water and dirt repellent coatings, and products coated with polymer containing coatings.
    Type: Application
    Filed: June 14, 2017
    Publication date: October 24, 2019
    Applicant: MERCK PATENT GMBH
    Inventors: Haibo FANG, Reiner FRIEDRICH
  • Bimesogenic compounds and mesogenic media
    Patent number: 10450508
    Abstract: The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula l in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: October 22, 2019
    Assignee: Merck Patent GmbH
    Inventors: Kevin Adlem, Owain Llyr Parri, Rachel Tuffin, Hassan Arasi, Benjamin Snow
  • Materials for organic electroluminescent devices
    Patent number: 10454041
    Abstract: The present invention relates to a process to produce compounds of the formula (1) which are suitable for use in electronic devices, as well as to intermediate compounds of formula (Int-1) and compounds of formula (1-1) and (1-2) obtained via the process. These compounds are particularly suitable for use organic electroluminescent devices. The present invention also relate to electronic devices, which comprise these compounds.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: October 22, 2019
    Assignee: Merck Patent GmbH
    Inventors: Teresa Mujica-Fernaud, Elvira Montenegro
  • Liquid crystal medium and liquid display
    Patent number: 10450509
    Abstract: Mesogenic media comprising one or more compounds of formulae I or II preferably mesogenic media showing a blue phase, preferably stabilized by a polymer, and their use in electro-optical light modulation elements and their respective use in displays, as well as such devices.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: October 22, 2019
    Assignee: MERCK PATENT GMBH
    Inventors: Michael Wittek, Norihiko Tanaka, Malgorzata Rillich, Volker Reiffenrath, Axel Jansen
  • Materials for electronic devices
    Patent number: 10454040
    Abstract: The invention relates to a mixture containing at least two different triaryl amino compounds of formula (I). The mixture is suitable for use in an electronic device, preferably in an organic electroluminescent device, and in particular for use as a hole transport layer.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: October 22, 2019
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Frank Voges, Arne Buesing, Christof Pflumm, Teresa Mujica-Fernaud, Jonas V. Kroeber
  • LIQUID-CRYSTALLINE MEDIUM
    Publication number: 20190316037
    Abstract: The invention relates to a liquid-crystalline medium having negative dielectric anisotropy comprising one or more compounds of formula I and one or more compounds selected from the group of the compounds of the formulae IIA, IIB and IIC, wherein the groups and parameters have the meanings indicated in claim 1, to a guest-host liquid crystal medium derived therefrom comprising one or more dichroic dyes and the use of said medium in devices such as light shutters, switchable windows, switchable mirrors and guest-host displays. The invention further relates to devices containing the liquid crystalline medium according to the invention.
    Type: Application
    Filed: October 16, 2017
    Publication date: October 17, 2019
    Applicant: Merck Patent GmbH
    Inventors: Jung-Min LEE, Hyun-Woo BAE, Dong-Mee SONG, Yong-Kuk YUN
  • METAL COMPLEXES
    Publication number: 20190315787
    Abstract: The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, containing these metal complexes.
    Type: Application
    Filed: July 11, 2017
    Publication date: October 17, 2019
    Applicant: Merck Patent GmbH
    Inventors: Philipp STOESSEL, Christian EHRENREICH