Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
Type:
Grant
Filed:
March 22, 2017
Date of Patent:
April 9, 2019
Assignees:
PROMERUS, LLC, MERCK PATENT GMBH
Inventors:
Larry F Rhodes, Hugh Burgoon, Irina Afonina, Tomas Backlund, Aurelie Morley
Abstract: Disclosed is a receptacle for accepting nutrient media, especially for bacterial cultures. Said receptacle comprises a dish and a lid that covers the dish. The dish and the lid each have a circular bottom (dish bottom and lid bottom) and an annular wall (dish wall and lid wall) that projects from the bottom. One of the walls, preferably the lid wall, has an at least slightly larger internal diameter than the external diameter of the other wall, preferably the dish wall, such that one wall can be slid onto the other wall to close the dish. In order to be able to safely handle the receptacle, engaging means which prevent the dish and the lid from being accidentally released when the same are mutually engaged, are associated with the dish and the lid.
Abstract: Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.
Type:
Grant
Filed:
October 1, 2015
Date of Patent:
April 9, 2019
Assignee:
MERCK PATENT GMBH
Inventors:
Markus Klein, Oliver Schadt, Philipp Haselmayer, Michael Busch
Abstract: The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Type:
Grant
Filed:
October 6, 2015
Date of Patent:
April 9, 2019
Assignee:
Merck Patent GmbH
Inventors:
Pascale Gaillard, Jeyaprakashnarayanan Seenisamy, Lesley Liu-Bujalski, Richard D. Caldwell, Justin Potnick, Hui Qiu, Constantin Neagu, Reinaldo Jones, Annie Cho Won, Andreas Goutopoulos, Brian A. Sherer, Theresa L. Johnson, Anna Gardberg
Abstract: The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
Type:
Application
Filed:
June 7, 2018
Publication date:
April 4, 2019
Applicant:
Merck Patent GmbH
Inventors:
Heidi ROMMELAERE, Joost Alexander KOLKMAN, Michael John Scott SAUNDERS, Ann UNION, Yolande CHVATCHKO, Amanda E.I. PROUDFOOT, Alain VICARI, Denis BRUNIQUEL, Laurent CHEVALET, Olivier LEGER
Abstract: The present invention relates to liquid crystal mixtures comprising one or more compounds of the formula A and, in addition one or more compounds of formula I or one or more compounds of formula II wherein the individual radicals have the respective meanings indicated in claim 1, to the use thereof for high-frequency components, and to high-frequency components, in particular antennae, especially for the gigahertz range, comprising these media.
Abstract: The present invention relates to electronic devices containing special cyclic lactams, more particularly organic electroluminescent devices, and to special cyclic lactams for use in electronic devices, more particularly in organic electroluminescent devices.
Type:
Grant
Filed:
January 11, 2016
Date of Patent:
April 2, 2019
Assignee:
Merck Patent GmbH
Inventors:
Philipp Stoessel, Amir Hossain Parham, Christof Pflumm, Anja Jatsch, Thomas Eberle, Jonas Valentin Kroeber
Abstract: The present invention relates to organic electroluminescent devices which comprise mixtures of at least one matrix material of the formula (1) and an emitting material which has a small singlet-triplet separation.
Type:
Grant
Filed:
March 18, 2014
Date of Patent:
April 2, 2019
Assignee:
Merck Patent GmbH
Inventors:
Philipp Stoessel, Amir Hossain Parham, Christof Pflumm, Anja Jatsch, Joachim Kaiser
Abstract: A liquid-crystalline medium, preferably having a nematic phase and exhibiting a dielectric anisotropy of 0.5 or more, which contains compounds of formula B and formula S in which denotes denotes the use thereof in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect, displays of this type which contain a liquid-crystalline medium of this type, and the use of the compounds of formula S for the improvement of the transmission and/or response times of a liquid-crystalline medium which contains one or more additional mesogenic compounds.
Type:
Application
Filed:
September 26, 2018
Publication date:
March 28, 2019
Applicant:
MERCK PATENT GMBH
Inventors:
Atsutaka MANABE, Constanze BROCKE, Herbert PLACH
Abstract: Compounds of the formula I in which Z, W, Q, R and Y have the meanings indicated in claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Abstract: The invention relates to substituted quinquephenyls of the formulae indicated in the claims and description. They are particularly suitable as UV-stabilizing component in liquid-crystalline media.
Type:
Grant
Filed:
September 17, 2015
Date of Patent:
March 26, 2019
Assignee:
MERCK PATENT GMBH
Inventors:
Christian Jasper, Timo Uebel, Detlef Pauluth, Michael Junge
Abstract: The present invention relates to non-metallic interference pigments, in particular laminar interference pigments, which comprise a thin high-refractive layer and an outermost layer that contains crystalline carbon in the form of graphite and/or graphene. The invention also relates to a method for producing such pigments and the use of the thus produced pigments.
Abstract: The present invention relates to the purification of poloxamers to be used as cell culture media additives. Activated carbon can be used to remove hydrophobic high molecular weight components which reduce the efficacy of poloxamers as cell culture additives.
Type:
Application
Filed:
February 20, 2017
Publication date:
March 21, 2019
Applicant:
MERCK PATENT GMBH
Inventors:
Anja LICHT, Almut RAPP, Joerg VON HAGEN
Abstract: The present invention relates to light-converting materials which comprise semiconductor nanoparticles and an unactivated crystalline material, where the semiconductor nanoparticles are located on the surface of the unactivated crystalline material. The present invention furthermore relates to the use of the light-converting material in a light source. The present invention furthermore relates to a light-converting mixture, to a light source, to a lighting unit which contains the light-converting material according to the invention, and to a process for the production of the light source.
Type:
Application
Filed:
August 17, 2016
Publication date:
March 21, 2019
Applicant:
Merck Patent GmbH
Inventors:
Norbert STENZEL, Andrea OPOLKA, Bernhard RIEGER, Stefan TEWS
Abstract: The present invention describes amines with dibenzofuran, dibenzothiophene and fluorene groups, especially for use as triplet matrix materials in organic electroluminescent devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.
Type:
Application
Filed:
February 6, 2017
Publication date:
March 21, 2019
Applicant:
Merck Patent GmbH
Inventors:
Amir Hossain PARHAM, Thomas EBERLE, Anja JATSCH, Tobias GROSSMANN, Jonas Valentin KROEBER, Elvira MONTENEGRO, Caroline WERN
Abstract: The invention relates to novel compounds containing one or more benzo[1,2-d;4,5-d?]bisthiazole-4,8-diyl (“BBT”) units, to methods for their preparation and educts or intermediates used therein, to mixtures and formulations containing them, to the use of the compounds, mixtures and formulations as organic semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising these compounds, mixtures or formulations.
Type:
Application
Filed:
March 10, 2017
Publication date:
March 21, 2019
Applicant:
Merck Patent GmbH
Inventors:
Lana NANSON, Agnieszka PRON, Michal KROMPIEC
Abstract: The present invention describes carbazolyl compounds substituted by electron-deficient heteroaryl groups, especially for use as triplet matrix materials in organic electroluminescent devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.
Type:
Application
Filed:
October 11, 2016
Publication date:
March 21, 2019
Applicant:
Merck Patent GmbH
Inventors:
Amir Hossain PARHAM, Aurélie LUDEMANN, Dominik JOOSTEN, Tobias GROSSMANN, Jonas Valentin KROEBER
Abstract: The present invention is related to a method for the production of single crystalline TiO2 flakes in the rutile crystal structure, to single crystalline TiO2 flakes obtained by this method as well as to the use thereof, especially as pigments in several application media.
Abstract: A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with 4-[(S)-2-azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide.
Abstract: Novel azaquinazoline carboxamide derivatives of formula (I) wherein W1, W2, W3, W4, R1, R2, R3 and m which are defined above, are p70S6K inhibitor, and can be employed, inter alia, for the treatment of hyperproliferative disorders.
Type:
Grant
Filed:
April 24, 2018
Date of Patent:
March 19, 2019
Assignee:
Merck Patent GmbH
Inventors:
Bayard R. Huck, Ruoxi Lan, Justin Potnick, Lizbeth Celeste DeSelm, Mark W. Cronin, Jr., Constantin Neagu, Xiaoling Chen, Roch Boivin, Theresa L. Johnson, Andreas Goutopoulos