Patents Assigned to Metaproteomics, LLC
  • Patent number: 10220068
    Abstract: Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: March 5, 2019
    Assignee: METAPROTEOMICS, LLC
    Inventors: Andrea Lyra Heller, Brian Carroll, Matthew L. Tripp, Jeffrey S. Bland
  • Publication number: 20140335061
    Abstract: Disclosed are compositions and methods comprising supplemented oils for improving health, reducing cardiovascular risk factors, or treating certain conditions.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 13, 2014
    Applicant: METAPROTEOMICS, LLC
    Inventors: Matthew L. Tripp, Robert H. Lerman
  • Patent number: 8815306
    Abstract: Methods and compositions that can be used to promote bone and joint health through amelioration, stabilization and repair of damage associated with various pathophysiological conditions are disclosed.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: August 26, 2014
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, Veera Konda, Anu Desai, Amy J. Hall, Jeffrey S. Bland
  • Publication number: 20140066520
    Abstract: Disclosed is a pharmaceutical composition including a therapeutic quantity of a COX-2 inhibitor having an IC50-WHMA COX-2/COX-1 ratio ranging from about 0.23 to about 3.33 with reduced gastrointestinal and cardiovascular toxicity. Also disclosed are methods for treating osteoarthritis, rheumatoid arthritis or acute pain with less side-effects and faster onset of action utilizing the disclosed pharmaceutical composition.
    Type: Application
    Filed: November 5, 2013
    Publication date: March 6, 2014
    Applicant: METAPROTEOMICS, LLC
    Inventor: Eric Hauser KUHRTS
  • Publication number: 20130337092
    Abstract: Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed. Additionally, said compositions and methods are used to reduce oxidized low density lipoproteins (OxLDL), myeloperoxidase (MPO), and plasminogen activator inhibitor-1 (PAI-1).
    Type: Application
    Filed: May 17, 2013
    Publication date: December 19, 2013
    Applicant: METAPROTEOMICS, LLC
    Inventors: Veera KONDA, Andrea Lyra HELLER, Anu DESAI, Brian CARROLL, Matthew L. TRIPP, Jeffrey S. BLAND
  • Patent number: 8609154
    Abstract: Disclosed is a pharmaceutical composition including a therapeutic quantity of a COX-2 inhibitor having an IC50-WHMA COX-2/COX-1 ratio ranging from about 0.23 to about 3.33 with reduced gastrointestinal and cardiovascular toxicity. Also disclosed are methods for treating osteoarthritis, rheumatoid arthritis or acute pain with less side-effects and faster onset of action utilizing the disclosed pharmaceutical composition.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: December 17, 2013
    Assignee: Metaproteomics, LLC
    Inventor: Eric H. Kuhrts
  • Patent number: 8557306
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: October 15, 2013
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell
  • Patent number: 8486457
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: July 16, 2013
    Assignee: Metaproteomics, LLC.
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell
  • Patent number: 8475850
    Abstract: Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzymes, such as glutathione S-transferases (GSTs), and NADPH quinone reductase (NQO1) activity.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: July 2, 2013
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, Veera Konda, Amy J. Hall, Anu Desai, Jeffrey S. Bland
  • Publication number: 20130156870
    Abstract: Phytonutrient based compositions and methods of using the same for preventing, reducing, or treating genetic damage induced by environmental toxins are disclosed.
    Type: Application
    Filed: December 14, 2012
    Publication date: June 20, 2013
    Applicant: METAPROTEOMICS, LLC
    Inventor: Metaproteomics, LLC
  • Publication number: 20130064913
    Abstract: Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions, kits, and methods are additionally disclosed for means to augment the activity of identified glucose and insulin regulating drugs.
    Type: Application
    Filed: June 1, 2012
    Publication date: March 14, 2013
    Applicant: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Amy J. Hall, Veera Konda, Linda M. Pacioretty
  • Publication number: 20120270837
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: April 30, 2012
    Publication date: October 25, 2012
    Applicant: METAPROTEOMICS, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell
  • Patent number: 8257754
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: September 4, 2012
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence M. Howell
  • Patent number: 8241674
    Abstract: Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzymes, such as glutathione S-transferases (GSTs), and NADPH quinone reductase (NQO1) activity.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: August 14, 2012
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, Veera Konda, Amy Hall, Anu Desai, Jeffrey S. Bland
  • Publication number: 20120189721
    Abstract: Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzymes, such as glutathione S-transferases (GSTs), and NADPH quinone reductase (NQO1) activity.
    Type: Application
    Filed: January 18, 2012
    Publication date: July 26, 2012
    Applicant: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, Veera Konda, Amy Hall, Anu Desai, Jeffrey S. Bland
  • Publication number: 20120183634
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 19, 2012
    Applicant: METAPROTEOMICS, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell
  • Publication number: 20120177756
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 12, 2012
    Applicant: METAPROTEOMICS, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell
  • Patent number: 8206753
    Abstract: Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions, kits, and methods are additionally disclosed for means to augment the activity of identified glucose and insulin regulating drugs.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: June 26, 2012
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Amy J. Hall, Veera Konda, Linda M. Pacioretty
  • Patent number: 8193201
    Abstract: The invention provides compositions containing a fraction isolated or derived from hops and a methylxanthine. The invention additionally provides compositions containing a fraction derived from hops and a curcuminoid. The invention also provides methods of using such compositions to reduce inflammation.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: June 5, 2012
    Assignee: Metaproteomics, LLC
    Inventors: John G. Babish, Matthew L. Tripp, Jeffrey S. Bland
  • Patent number: 8168234
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: May 1, 2012
    Assignee: Metaproteomics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Jeffrey S. Bland, Gary K. Darland, Robert Lerman, Daniel O. Lukaczer, DeAnn J. Liska, Terrence Howell