Abstract: Methods are provided for making a reservoir-based sensor device. The method may include fabricating a first substrate portion which comprises an upper surface, an opposed lower surface, a plurality of through holes defining reservoirs between said upper surface and said lower surface, and a plurality of reservoir caps closing off one end of said through holes at said upper surface; fabricating a plurality of sensors on an upper surface of a second substrate portion; aligning the first and second substrate portions such that each of said plurality of sensors is in alignment with each of said plurality of reservoirs; and bonding together the lower surface of said first substrate portion and the upper surface of said second substrate portion to seal each of said sensors inside the reservoir with which it is aligned.

Abstract: At a receiver incoming coded OFDM Symbol Data are passed through a Coarse Symbol Timing Synchronization module to determine the approximate start of the symbol. In one embodiment this is accomplished through correlation. The symbol is then passed through an FFT (2K or 8K, depending on the mode desired by the receiver). Since the Coarse Symbol Timing Synchronization module only determines an approximate start point of the symbol, a process of fine synchronization is used to adjust this approximate start point and determine a more accurate start point of the symbol. In this manner, the receiver is enabled to process COFDM symbols in DVB-T transmissions (where the symbols include a cyclic prefix to overcome echoes). One output of an FFT operation is magnitude. Magnitude is used for Channel Estimation (or Channel Correction). Another output of an FFT operation is phase discontinuity or rotations. Phase discontinuities are used in a fine synchronization process to determine the number of phase discontinuities.

Abstract: Methods for operating a sensor device are provided, which may include (a) providing at a site (e.g., implanting in a patient) a device which comprises at least first and second reservoirs, a first sensor and corresponding first reference sensor located within the first reservoir, a second sensor and corresponding second reference sensor located within the second reservoir, a first reservoir cap closing an opening in the first reservoir and a second reservoir cap closing an opening in the second reservoir, and a power source, control circuitry, and electrodes for selectively disintegrating each reservoir cap; (b) disintegrating the first reservoir cap and operating the first sensor and reference sensor; and (c) using the first reference sensor to determine whether the first sensor is operating properly. If not operating properly, then the control circuitry initiates disintegration of the second reservoir cap and operation of the second sensor and reference sensor.

Abstract: Determining a horizontal resolution and a phase of an analog video signal arranged to display a number of scan lines each formed of a number of pixels is described. A number of initialization values are set where at least one of the initialization values is a current horizontal resolution and then a difference value for each immediately adjacent ones of the pixels is determined. Next, an edge flag value based upon the difference value is stored in at least one of a number of accumulators such that when at least one of the accumulators has a stored edge flag value that is substantially greater than those stored edge flag values in the other accumulators, then the horizontal resolution is set to the current resolution.

Abstract: Systems and methods for creating virtual stop-off points in a movie title, where the viewer can explore interesting content using zoom, pan and gamma controls are provided. Methods include creating an interest point from one or more digital video titles. Systems include a composer for creating interest points in a video and a viewer for manipulating and displaying the interest points.

Abstract: Devices and methods are provided for wirelessly powering and/or communicating with implanted medical devices used for the controlled exposure and release of reservoir contents, such as drugs or sensors. The device may include a substrate having a plurality of reservoirs containing reservoir contents for release or exposure; and a rechargeable or on-demand power source comprising a local component which can wirelessly receive power from a remote transmitter wherein the received power can be used, directly or following transduction, to activate the release or exposure of the reservoir contents.

Abstract: Methods of pre-clinical animal testing to monitor physiological parameters of test animals following exposure of molecules sealed in reservoirs on implanted devices. The test molecules are exposed to physiological fluid of the animal. The molecules can be configured as a sensor chemistry that reacts with the physiological fluid. The molecules can be a drug or drug candidate that is released into the animal. The test animals are non-human mammals.

Abstract: A method of overdriving LCD panels to improve LCD pixel response time is described that does not rely upon conventional use of overdrive look up tables. The method is based upon modeling the LCD pixels as linear second-order dynamical systems that leads to simple runtime calculations requiring but a small number of stored panel specific constants.

Abstract: Methods are provided for medical treatment or diagnosis of a patient. The method includes implanting into the patient a device which comprises (i) a substrate in which at least one reservoir is located and covered by a first reservoir cap, (ii) a drug or sensor located in the reservoir, and (iii) control circuitry and a power source for disintegrating or permeabilizing the reservoir cap, and (iv) an external interface to receive incident light energy; and directing focused light to the external interface of the implanted device to actuate disintegration or permeabilization of the reservoir cap to release the drug or expose the sensor. The device may implanted onto or into the sclera or other tissue surface of the eye of the patient. The focused light may be laser light which may be used to transmit power or data to the device.

Abstract: Methods and apparatus, including computer program products, implementing and using techniques for computing motion vectors in a digital video sequence are disclosed. A recursive hierarchical method is used to determine a motion vector by using multiple resolution levels of the image frames. A best motion vector is first determined for the lowest resolution level. The best motion vector is propagated to a higher resolution level, where some adjustments are made and a new best motion vector is determined. The new best motion vector is propagated to yet another higher resolution level, where more adjustments are made and another new best motion vector is determined. This process is repeated until the highest, original, resolution level has been reached and a best motion vector has been identified. The identified best motion vector at the original resolution level is used for performing motion compensation.

Abstract: A memory efficient providing LC overdrive for sticky pixels at a frame n?1 for a current frame n based upon sticky pixel data associated with a frame n?2.

Abstract: Disclosed herein are methods and apparatus, including computer program products, implementing and using techniques for reducing mosquito noise in an image frame of a video signal. A window of the image frame is provided. The window includes a plurality of pixel values. One of the pixel values is selected from the pixel values in the window to define a modified window of pixel value differences. A local mean (DC) value is computed based on the pixel value differences. A mosquito noise reduction value is also computed based on the pixel value differences. An artifact attenuation factor is computed as a function of a dynamic range measure of the pixel value differences. A weighted sum of the mosquito noise reduction value and the local mean value, applying the artifact attenuation factor, and the selected pixel value, is computed to generate a modified pixel value.

Abstract: An over-sampled sequence detector operates on sampled data and tracks the detection reliability of the sampled data. The detector separately analyzes sample sequences for different sampling phases and then picks a sample sequence that allows for the most reliable detection. For the different sampling phases, the detector inspects some amount of look-behind and look-ahead information in order to improve upon simple symbol-by-symbol detection. The over-sampled information is used to further improve detection performance.

Abstract: Methods and apparatus, including computer program products, implementing and using techniques for computing motion vectors in a digital video sequence are disclosed. A recursive hierarchical method is used to determine a motion vector by using multiple resolution levels of the image frames. A best motion vector is first determined for the lowest resolution level. The best motion vector is propagated to a higher resolution level, where some adjustments are made and a new best motion vector is determined. The new best motion vector is propagated to yet another higher resolution level, where more adjustments are made and another new best motion vector is determined. This process is repeated until the highest, original, resolution level has been reached and a best motion vector has been identified. The identified best motion vector at the original resolution level is used for performing motion compensation.

Abstract: Disclosed herein are methods and apparatus, including computer program products, implementing and using techniques for reducing mosquito noise and blockiness in an image frame of a video signal. A border of a pixel block is determined, and if the region surrounded by the border is determined to be associated with mosquito noise or blockiness, then the mosquito noise or blockiness, respectively, is reduced in the region only.

Abstract: Implantable medical devices for cardiac care are provided that include a housing having a power source and control electronics; at least one lead extending from the housing and having one or more discrete reservoirs therein, each reservoir having an opening to an outer surface of the lead; one or more sensors, which monitor or detects an analyte, biomarker, or physical parameter that is associated with cardiac health, located in the reservoirs and in operable communication with said control electronics; and at least one selectively disintegratable reservoir cap sealing each of the reservoir openings, wherein the reservoir cap is operably connected to the power source and control electronics to disintegrate the reservoir cap and expose the sensors in vivo. The sensor may detect an analyte or biomarker selected from potassium ion, sodium ion, lithium ion, magnesium ion, ammonium ion, ionized calcium, lactate, oxygen, carbon dioxide, and creatinine, urea, BUN, and bilirubin.

Abstract: In a liquid crystal display (LCD) panel based display, a method of dynamically selecting either frame rate conversion (FRC) or pixel voltage overdrive is disclosed. The method is carried out by performing the following operations. A video vertical refresh rate of an incoming video data stream is determined and based upon the determining, only one video data stream conditioning protocol from a number of available video data stream conditioning protocols is selected. The selected video data stream condition protocol is then applied to the video data stream.

Abstract: An apparatus comprising a video decoder configured to receive a composite video signal modulated on a sub-carrier signal and having a luma component and a chroma component, the video decoder configured to perform a motion detection operation on the luma component and the chroma component in a plurality of frequency regions respectively. The video decoder includes variable threshold logic, coupled to the video decoder, and configured to provide a unique threshold value to the video decoder for each of the plurality of frequency regions respectively. The apparatus also includes a sub-carrier detection logic, coupled to the variable threshold logic, and configured to detect the sub-carrier signal by checking both spatial and temporal characteristics of the sub-carrier detection logic.

Abstract: A pump patch device is provided for drug delivery. The device may include a substrate having a plurality of discrete reservoirs, each reservoir having a reservoir opening; a drug disposed in the reservoirs; a pump for delivering a carrier fluid through or adjacent to the reservoir openings; a flow channel for receiving and combining the carrier fluid from the pump with the drug from the reservoirs to form a fluidized drug; and a needle for delivering the fluidized drug into the skin or another biological tissue of a patient. A device is provided for use in dialysis that includes a non-disposable module including a pump or pressure generator; and a disposable cassette operably connected to the pump or pressure generator and including a plurality of discrete reservoirs containing drug and sensors. A fluidics connection device is provided that includes a compression cold weld seal for a microfluidic via.

Abstract: An interlaced television signal is derived from an interlaced 625 line, nominally 50 Hz field rate television signal, the derived television signal having perceived reduced line structure and reduce flicker. The field rate and the number of lines of the derived television signal are increased with respect to the field rate and the number of lines of the original television signal, such that perceived flicker and line structure in the derived television signal is reduced. The increase in the field rate and the increase in the number of lines in the derived television signal results in a horizontal scanning rate that does not substantially exceed twice the horizontal scanning rate of the original television signal while minimizing undesirable motion artifacts.