Abstract: The present invention relates to a method and a system (400) for filling a closed container (200) with a fixative solution. The system comprises a container (200) comprising a container body (230) for receiving a biological specimen, a lid (220) for selectively closing the container body (230) and a port (100) forming a unidirectional barrier in a direction from the inside (IC) to the outside (OC) of the closed container (200). The system further comprises a dispensing apparatus (500) having a filling nozzle (300) for dispensing the fixative solution. The filling nozzle (300) is relatively moveable with respect to the container (200) between a retracted position and a filling position to fill the container (200) with the fixative solution.

Abstract: The present invention relates a spectrometer (1) having a lamp (2) that extends in substantially tubular fashion for the purposes of forming a light emission zone (3) that extends in the direction of the tubular extent and between two points to the end of emitting a first light beam (L1) and a second light beam (L2) that have the same origin on the light emission zone (3), a sample container (6) that is arranged in the beam path of the first light beam (L1) for receiving a sample to be measured, a first detection apparatus (D1) that is arranged in the direction of the first light beam (L1) for quantitative and/or qualitative determination of the sample to be measured in the sample container (6) on the basis of an interaction between the sample to be measured and the first light beam (L1), and a second detection apparatus (D2) that is arranged in the direction of the second light beam (L2) for the purposes of referencing the quantitative and/are qualitative determination, on the basis of the second light beam

Abstract: Measuring apparatus (1) for tracking human and/or animal tissues comprising: a working area (2) for receiving a tissue; a detecting unit (5) configured to detect a unique tissue code provided with the tissue placed on the working area (2); a measuring unit (9) configured to automatically measure quantitative properties of the tissue placed on the working area (2); and a processing and storing unit (22) configured to automatically link the quantitative properties with the tissue code and to automatically store the so linked quantitative properties and tissue code such that the quantitative properties can be retrieved based on the tissue code.

Abstract: The invention refers to a container (1) for collecting, transporting and storing biological tissue samples, wherein the container (1) is filled with a first component (3) being a fixative and a second component (4) being a fluid, wherein the second component (3) has a lower specific gravity compared to the fixative (3), and is immiscible with the fixative (3). The second component (4) is stratified on top of the fixative (3) to form a protective film to prevent fixative fumes to escape from the container (1). The invention further relates to a method for collecting, transporting and storing biological tissue samples.

Abstract: A device for the extraction of a compound from a solid material, which includes a microwave unit enclosing an inner vessel that is configured to hold a solid and that is fluidly sealed within an outer vessel configured to hold a solvent to be vaporized, and a condenser that is arranged to condense the vaporized solvent and deliver the condensed solvent to the inner vessel is described. The inner vessel has a solvent outlet configured to deliver condensed solvent that contains an extracted compound back to the outer vessel. The device includes a stirrer within the outer vessel and a stirrer within the inner vessel to provide agitation during the extraction process.

Abstract: A method for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample comprises placing the bag with the sample in a dosing system (e.g., on a holder or weighing device), computing a required volume or weight of fixative solution as a function of the sample or the bag with the sample, and automatically transferring the computed volume or weight of fixative solution from a storage container into the bag. A system is also described for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample, a carrier for said flexible bags, and a storage cabinet for storing the carrier.

Abstract: A method for fixation of organic tissue samples includes immersing a tissue sample in a solution of Formalin at a temperature of between 2° C. and 10° C. for a first time period (A), and immersing the tissue sample in a cold fixation dehydrating agent for a second time period (B) following the first time period. An automated tissue fixation system for fixating organic tissue samples in Formalin is also described.

Abstract: The present invention relates to a new method of extraction of solid compounds by microwaves and to the apparatus used in said method.

Abstract: A method for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample comprises placing the bag with the sample in a dosing system (e.g., on a holder or weighing device), computing a the required volume or weight of fixative solution as a function of the sample or the bag with the sample, and automatically transferring the computed volume or weight of fixative solution from a storage container into the bag. A system is also described for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample, a carrier for said flexible bags, and a storage cabinet for storing the carrier.

Abstract: A method for processing frozen slices of tissue of biospecimens mounted on or adhered to glass slides, i.e. forming a frozen section (2), and arranged on a carrier (1), has the following steps: a.) immersing the frozen tissue slices in a fixative, b.) staining the tissue slice, c.) dehydrating the tissue slice, and d.) optionally clearing the tissue slice. Steps a.) to d.) are performed by automatically transferring the frozen sections (2) on the carrier (1) between and into and out of at least a container (C1) holding a fixative, at least one or optionally more, preferably two containers (C3, C5) holding a staining solution, a container (C6, C7) holding a dehydrating solution, and optionally a container (C8) holding a clearing solution. The transfer and the time duration during which the tissue slices are in said containers (C) are controlled by a control unit controlling an actuator (10).

Abstract: A method for fixation of organic tissue samples includes immersing a tissue sample in a solution of Formalin at a temperature of between 2° C. and 10° C. for a first time period (A), and immersing the tissue sample in a cold fixation dehydrating agent for a second time period (B) following the first time period. An automated tissue fixation system for fixating organic tissue samples in Formalin is also described.

Abstract: A process for preserving tissues is described which comprises transferring the tissues in a container and evacuating the container.

Abstract: A process for preserving tissues is described which comprises transferring the tissues in a container and evacuating the container.

Abstract: This invention relates to a quality control method for improving histoprocessing, as well as a device for measuring the thickness of an organic tissue sample suited for use in the method.

Abstract: A system and for automatic histoprocessing of organic tissue specimens using microwaves, two cavities and automatic fluid and specimen transfer between the two cavities.

Abstract: A devise for carrying out chemical reactions and processes in high-frequency fields, comprises a high-frequency chamber 2 for irradiating a solid, liquid or gaseous substance while under pressure with at least one radiation source and a reactor for exposing to a high-frequency field. The reactor being connectively coupled to the upper wall 4 of the high-frequency chamber 2 through a sealable connection 3. Rail elements 5 are provided around the reactor, and configured to form a pressure-resistant cage. The rail elements 5 each have a guide 11 for holding a crown-shaped holder 12. The holder 12 is fixed in its position by the guides 11 of the rail elements 5. Multiple reaction chambers can be incorporated as a batch reactor system.

Abstract: The present invention describes a fixative composition comprising ethanol, water, 1,2-propanediol, polyvinyl alcohol and an effective amount of at least one monomeric polyhydroxy compound. The fixative composition may be used in histopathology, cytology and immunohistochemistry.

Abstract: A magazine-type sample rotation body (7) is arranged in a high frequency chamber (5) so that it rotates away from the horizontal, the body (7) accommodating, in fixed location, reactor blocks (10) that are sealed or sealable from fluids such that fluids contained in sample vessels in the reactor blocks can be mixed before, during and after high frequency exposure because of the rotational movement of the sample rotation body.

Abstract: A system and method for controlling a microwave heated chemical process is disclosed. Time varying concentrations of some chemical substances within fumes in the microwave oven are monitored to detect concentration variations for which responses are known. Responses to the detected variations are initiated to control the chemical process without terminating the process. Examples of responses include varying microwave radiation energy, initiating safety systems, increased venting of the microwave oven, and so forth.

Abstract: Disclosed is an apparatus for use within a microwave radiation field which enables the operator to perform successively a plurality of chemical or physical processes while the apparatus remains in the microwave cavity. The apparatus according to the invention can be used to perform a total microwave solvent extraction including the steps of drying, extraction, filtration, and concentration. Other examples of processes, which are carried out with this apparatus are digestions, hydrolyses, separations, agitations, and precipitations. The apparatus is constructed from a container having an inside vessel. The container and the inside vessel have a substantially closed volume there between. The container and the inside vessel are in fluid communication through a glass fiber filter disposed at approximately the bottom of the inside vessel.