Patents Assigned to Milestone s.r.l.
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Publication number: 20090191533Abstract: A process for preserving tissues is described which comprises transferring the tissues in a container and evacuating the container.Type: ApplicationFiled: December 9, 2008Publication date: July 30, 2009Applicant: Milestone S.r.l.Inventor: Giovanni Bussolati
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Publication number: 20080318265Abstract: This invention relates to a quality control method for improving histoprocessing, as well as a device for measuring the thickness of an organic tissue sample suited for use in the method.Type: ApplicationFiled: June 24, 2008Publication date: December 25, 2008Applicant: Milestone S.r.l.Inventor: Francesco Visinoni
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Patent number: 7075045Abstract: A system and for automatic histoprocessing of organic tissue specimens using microwaves, two cavities and automatic fluid and specimen transfer between the two cavities.Type: GrantFiled: February 25, 2005Date of Patent: July 11, 2006Assignee: Milestone S.r.l.Inventor: Franco Visinoni
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Patent number: 6949227Abstract: A devise for carrying out chemical reactions and processes in high-frequency fields, comprises a high-frequency chamber 2 for irradiating a solid, liquid or gaseous substance while under pressure with at least one radiation source and a reactor for exposing to a high-frequency field. The reactor being connectively coupled to the upper wall 4 of the high-frequency chamber 2 through a sealable connection 3. Rail elements 5 are provided around the reactor, and configured to form a pressure-resistant cage. The rail elements 5 each have a guide 11 for holding a crown-shaped holder 12. The holder 12 is fixed in its position by the guides 11 of the rail elements 5. Multiple reaction chambers can be incorporated as a batch reactor system.Type: GrantFiled: March 27, 2001Date of Patent: September 27, 2005Assignee: Milestone S.r.l.Inventors: Werner Lautenschläger, Bernd Ondruschka, Matthias Nüchter
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Publication number: 20050074422Abstract: The present invention describes a fixative composition comprising ethanol, water, 1,2-propanediol, polyvinyl alcohol and an effective amount of at least one monomeric polyhydroxy compound. The fixative composition may be used in histopathology, cytology and immunohistochemistry.Type: ApplicationFiled: July 16, 2003Publication date: April 7, 2005Applicant: Milestone S.r.l.Inventor: Francesco Visinoni
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Patent number: 6717119Abstract: A magazine-type sample rotation body (7) is arranged in a high frequency chamber (5) so that it rotates away from the horizontal, the body (7) accommodating, in fixed location, reactor blocks (10) that are sealed or sealable from fluids such that fluids contained in sample vessels in the reactor blocks can be mixed before, during and after high frequency exposure because of the rotational movement of the sample rotation body.Type: GrantFiled: January 18, 2002Date of Patent: April 6, 2004Assignee: Milestone S.r.l.Inventors: Bernd Ondruschka, Matthias Nüchter, Werner Lautenschläger
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Publication number: 20030194352Abstract: The invention relates to a device 51 for closing a plurality of digestion vessels 1 the openings of which are in each case covered by a cover 3, comprising a plurality of positioning spaces 53 for the digestion vessels, the positioning spaces 53 being able to be distributed in a circumferential row R1 and being accessible from outside, and a plurality of closing devices 73 for pressing the covers 3 against the vessels. In order to improve the capacity of the device 51 with regard to the number of digestion vessels 1 further inner positioning spaces 53 are arranged to be offset inwardly with respect to said positioning spaces 53.Type: ApplicationFiled: February 20, 2003Publication date: October 16, 2003Applicant: MILESTONE S.R.L.Inventor: Werner Lautenschlager
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Publication number: 20030127313Abstract: A pot-like digestion vessel (1), which is closed by a cover (3), is provided with adjustable automatic internal pressure relief by means of a pressure applying plunger (6) which is held in a screwing part (7) via a resilient pressure generating mans (8) to press against the cover (3). In another embodiment the plunger (6) holds a valve body (33) in an outlet channel (31) which extends through the cover (3).Type: ApplicationFiled: December 12, 2002Publication date: July 10, 2003Applicant: MILESTONE S.r.l.Inventor: Werner Lautenschlager
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Publication number: 20030127311Abstract: A device 5 for closing pot-like digestion vessel 1 whose opening is covered by a cover 3, has a pressure-applying plunger 6, a screwing part 7 arranged co-axially with the pressure applying plunger 6 and a resilient pressure-generating means 8 arranged between the pressure-applying plunger 6 and the screwing part. The screwing part and the pressure-applying plunger 6 fit round one another in a socketed arrangement.Type: ApplicationFiled: March 15, 2002Publication date: July 10, 2003Applicant: MILESTONE S.R.L.Inventor: Werner Lautenschlager
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Patent number: 6455317Abstract: A system and method for controlling a microwave heated chemical process is disclosed. Time varying concentrations of some chemical substances within fumes in the microwave oven are monitored to detect concentration variations for which responses are known. Responses to the detected variations are initiated to control the chemical process without terminating the process. Examples of responses include varying microwave radiation energy, initiating safety systems, increased venting of the microwave oven, and so forth.Type: GrantFiled: March 6, 2000Date of Patent: September 24, 2002Assignee: Milestone s.r.L.Inventor: Werner Lautenschlager
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Patent number: 6242723Abstract: Disclosed is an apparatus for use within a microwave radiation field which enables the operator to perform successively a plurality of chemical or physical processes while the apparatus remains in the microwave cavity. The apparatus according to the invention can be used to perform a total microwave solvent extraction including the steps of drying, extraction, filtration, and concentration. Other examples of processes, which are carried out with this apparatus are digestions, hydrolyses, separations, agitations, and precipitations. The apparatus is constructed from a container having an inside vessel. The container and the inside vessel have a substantially closed volume there between. The container and the inside vessel are in fluid communication through a glass fiber filter disposed at approximately the bottom of the inside vessel.Type: GrantFiled: July 29, 1999Date of Patent: June 5, 2001Assignee: Milestone s.r.l.Inventor: Werner Lautenschlager
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Patent number: 6054695Abstract: Disclosed is an apparatus for condensing vapors for use inside a microwave cavity. The cooling in the apparatus is provided by gas flow ventilation with air being the most convenient gas for use as a coolant. The apparatus has two ports, one port for connecting with a sample vessel and a second port for connecting with a pressure control device. The pressure control device has valves for operating a vacuum line and a feeding line. The disclosed apparatus enables a plurality of chemical digestion reactions, reflux reactions and dehydrations to be carried out simultaneously or sequentially within a microwave radiation field.Type: GrantFiled: July 30, 1998Date of Patent: April 25, 2000Assignee: Milestone S.r.l.Inventor: Werner Lautenschlager
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Patent number: 6042874Abstract: This invention relates to the processing of organic tissues to prepare them for further investigation such as by light microscopy, electron microscopy, microwave staining, immunostaining, decalcification, hybridisation etc.The present invention discloses a process for processing organic tissue, which comprises the steps of fixing an organic sample to be processed, dehydrating and clearing the sample and subsequently infiltrating and embedding the sample in a supporting medium to prepare it for further examination wherein the steps of dehydrating and clearing are carried out simultaneously by applying a mixture of a dehydration agent and an essentially lipophilic agent simultaneously to the sample.Type: GrantFiled: November 23, 1998Date of Patent: March 28, 2000Assignee: Milestone S.r.l.Inventors: Francesco Visinoni, Werner Lautenschlager
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Patent number: 6033912Abstract: A system and method for controlling a microwave heated chemical process is disclosed. Time varying concentrations of some chemical substances within fumes in the microwave oven are monitored to detect concentration variations for which responses are known. Responses to the detected variations are initiated to control the chemical process without terminating the process. Examples of responses include varying microwave radiation energy, initiating safety systems, increased venting of the microwave oven, and so forth.Type: GrantFiled: November 13, 1997Date of Patent: March 7, 2000Assignee: Milestone S.r.l.Inventor: Werner Lautenschlager