Patents Assigned to MODERNA THERAPEUTICS, INC.
  • MODIFIED POLYNUCLEOTIDES ENCODING COPPER METABOLISM (MURR1) DOMAIN CONTAINING 1
    Publication number: 20140105965
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: December 12, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • MODIFIED POLYNUCLEOTIDES ENCODING APOPTOSIS INDUCING FACTOR 1
    Publication number: 20140107189
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Stephane Bancel, Tirtha Chakraborty, Antonin de Fougerolles, Susan Whoriskey, Ron Weiss
  • Modified polynucleotides for the production of G-CSF
    Patent number: 8680069
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Grant
    Filed: May 18, 2013
    Date of Patent: March 25, 2014
    Assignee: Moderna Therapeutics, Inc.
    Inventors: Antonin de Fougerolles, Kristy M. Wood, Sayda M. Elbashir, Jason P. Schrum
  • Method for producing a protein of interest in a primate
    Patent number: 8664194
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: March 4, 2014
    Assignee: Moderna Therapeutics, Inc.
    Inventors: Antonin de Fougerolles, Kristy M. Wood, Sayda M. Elbashir, Jason P. Schrum
  • MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF
    Publication number: 20130203115
    Abstract: The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using thereof.
    Type: Application
    Filed: January 11, 2013
    Publication date: August 8, 2013
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventor: MODERNA THERAPEUTICS, INC.