Abstract: Cancers of different cellular or tissue origins express different ENOX2 cancer isoforms or combinations of isoforms and shed these proteins into the circulation. Herein are disclosed methods both for cancer detection and diagnosis of particular origin, based on the patterns and molecular weights of the isoforms which allow the identification of the cell type and or tissue of origin of the neoplasm. Relative ENOX2 amounts are proportional to tumor burden and provide a reliable measure of response to therapy and disease progression. Also provided is the amino acid sequence to which the scFv antibodies bind as the molecular basis for the specificity of the test.

Abstract: A dental implant including a first, apical portion for inserting into bone, and a second, top-side portion, starting at a level of bone surface and higher, including a stricture of the dental implant diameter, relative to a diameter of the top-side portion, for at least part of the top-side portion. Related apparatus and methods are also described.

Abstract: This disclosure relates to compositions for use in treatment of Alzheimer's Disease, and/or a ocular and retinal degenerative disease, such as age related macular degeneration. The described compositions include effective amounts of LLMe, the hydrobromide form thereof, or functional derivatives thereof. Methods of treatment of a retinal degenerative disease of Alzheimer's Disease using the described compositions are also provided.

Abstract: A method for evaluating a treatment for a brain condition, including: extracting one or more microstate parameter values from at least one EEG signal that was measured after the treatment; evaluating at least one parameter of the treatment based on the one or more microstate parameter values.

Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.

Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.

Abstract: A method for preventing bleeding, blood-brain barrier disruption, brain injury, or a combination thereof in a subject destined for cardiac surgery is disclosed. The method involves administering to the subject prior to cardiac surgery a therapeutically effective amount of alpha-1 antitrypsin (AAT-1), or functional variant thereof. The result is that it prevents bleeding, blood-brain barrier disruption, or a combination thereof in a subject destined for cardiac surgery.

Abstract: The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL, and appropriate associated treatments thereof.

Abstract: A method of treating a malignant disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a first liquid chromatography fraction of a Cannabis extract comprising at least 75% tetrahydrocannabinolic acid (THCA), and a therapeutically effective amount of a second liquid chromatography fraction of a Cannabis extract comprising at least 75% cannabigerolic acid (CBGA), wherein the first liquid chromatography fraction comprises Cannabis derived active ingredients other than the THCA, and the second liquid chromatography fraction comprises Cannabis derived active ingredients other than the CBGA, thereby treating the malignant disease in the subject.

Abstract: A system for vital sign measuring of a patient, comprising: a first sensor removably attachable with a first body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; at least one additional sensor removably attachable with a second body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; and a processor configured to provide data descriptive of a level of correspondence between measurements of the vital signs provided by the first sensor and the at least one additional sensor.

Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.

Abstract: According to some embodiments there is provided a wearable device for breast screening, comprising: at least one breast-contacting member shaped to contact a surface of a breast, the member comprising an array of force applying units and an array of sensors configured for sensing at least one parameter in response to force applied by the force applying units; the force applying units and the sensors disposed on or within the breast-contacting member and positioned to contact a surface of the breast; a memory storing one or more patterns suitable to detect a lump underlying the surface; wherein the pattern comprises a sequence of forces that vary spatially and/or vary in time; a controller configured for: reading data from the memory to control application of force; communicating with the sensors to receive signals associated with the at least one parameter sensed in response to the application of force; and to process the received signals to detect a lump.

Abstract: A method and system are disclosed for opening a workspace inside a lumen of a living creature are disclosed. Anchors may be affixed to opposite ends of the workspace. An extender may be distance anchors apart while they are affixed to the walls of the workspace. Distancing the anchors may unfold and/or stretch the lumen in the region of the workspace.

Abstract: A system for detecting a vehicle traveling a designated direction of travel on a roadway includes a sign having a front surface and a back surface. The sign may include a sign boundary marker that is different in color than a color of the front surface. One or more light panels such as an LED light panel is affixed to the sign such as to its front surface. The light emitting elements may lie below a top plane of the light panel. A color of a top surface of the light panel matches a color on the front surface of the sign over which the light panel is placed. A vehicle motion detector or proximity detector is oriented in a direction and has a detection zone for detecting moving vehicles in proximity to the sign. The detector illuminates the lights of the light panel after detecting a moving vehicle in proximity to the sign.