Patents Assigned to MORS
  • TREATMENTS FOR FIBROTIC DISEASES
    Publication number: 20160206591
    Abstract: Disclosed herein are methods for treatment for fibrosis, ocular pathologies associated with fibrosis, including proliferative vitreoretinopathy (PVR) by inhibiting the activity of activated transforming growth factor ? activated kinase 1 (TAK1), or activation thereof. Pharmaceutical compositions for use in the described treatments are also provided.
    Type: Application
    Filed: March 29, 2016
    Publication date: July 21, 2016
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Ayala Pollack, Zeev Dvashi
  • DEVICE FOR PLACEMENT IN THE TRICUSPID ANNULUS
    Publication number: 20160184098
    Abstract: A device (200) for implantation in or near an annulus of a tricuspid valve comprising at least one blood flow control element (202) adapted to capture a volume of blood therein. Optionally or alternatively, the blood flow control element is adapted to allow at least some volume of blood (406) to regurgitate through the annulus during at least some part of systole. Optionally or alternatively, the device comprises a relatively rigid annulus with an arc length of less than 300 degrees. Optionally or alternatively, the relatively rigid annulus comprises a plurality of tissue fixation elements positioned along no more than 300 degrees of a circumference of the annulus, for example to avoid damaging conduction pathways between an atria and a chamber.
    Type: Application
    Filed: March 10, 2016
    Publication date: June 30, 2016
    Applicant: Mor Research Applications Ltd.
    Inventor: Mordehay VATURI
  • Methods and compositions for diagnosing complications of pregnancy
    Patent number: 9334540
    Abstract: The present invention provides methods and compositions for identifying subjects at risk of developing a complication of pregnancy, such as preeclampsia or preterm labor. The compositions are microRNAs and associated nucleic acids.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: May 10, 2016
    Assignees: Rosetta Genomics Ltd., MOR Research Applications
    Inventors: Yaron Goren, Shlomit Gilad, Moshe Hod, Yariv Yogev
  • COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES
    Publication number: 20160114006
    Abstract: This disclosure relates to compositions for use in treatment of a retinal degenerative disease, such as age related macular degeneration. The described compositions include agents for activating p38 and/or JNK signaling through the activation of TAK1 in the retinal pigment epithelium of a subject diagnosed with the disease. Methods of treatment of a retinal degenerative disease using the described compositions are also provided.
    Type: Application
    Filed: May 29, 2014
    Publication date: April 28, 2016
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventors: Ayala POLLACK, Zeev DVASHI
  • COMPOSITIONS AND METHODS FOR TREATING POST-OPERATIVE COMPLICATIONS OF CARDIOPULMONARY SURGERY
    Publication number: 20160089423
    Abstract: Disclosed herein are compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ failure, by administering a pharmaceutical composition comprising alpha-1 antitrypsin (AAT).
    Type: Application
    Filed: May 12, 2014
    Publication date: March 31, 2016
    Applicant: MOR RESEARCH APPLICATIONS LTD.
    Inventor: Dan Abrahamov
  • METHOD AND SYSTEM FOR ANALYZING CRANIOFACIAL COMPLEX IMAGES
    Publication number: 20160029927
    Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.
    Type: Application
    Filed: October 5, 2015
    Publication date: February 4, 2016
    Applicants: Ramot at Tel-Aviv University Ltd., Mor Research Applications Ltd.
    Inventors: Yehuda FINKELSTEIN, Lior WOLF
  • Method of treatment of small for gestational age infants under two years of age
    Patent number: 9168289
    Abstract: The invention provides a method and a composition for the treatment of infants age less than 2.5 years old defined as small for gestational age (SGA), including the use of hGH or any compound that increases blood levels of hGH or of IGF-I. Early use of the composition prevents the irreversible neurological and psychological damage of the children.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: October 27, 2015
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventor: Zvi Laron
  • NUCLEIC ACID DETECTION ASSAY
    Publication number: 20150299805
    Abstract: This invention is directed, inter alia, to methods and kits for rapid, easy and cost-effective methods of breast cancer prediction and diagnosis in inter alia, blood samples.
    Type: Application
    Filed: January 9, 2015
    Publication date: October 22, 2015
    Applicants: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY, MOR RESEARCH APPLICATIONS LTD.
    Inventor: Amos Douvdevani
  • Method and system for analyzing craniofacial complex images
    Patent number: 9153022
    Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: October 6, 2015
    Assignees: Mor Research Applications Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Yehuda Finkelstein, Lior Wolf
  • Apparatus and method for analyzing stream of imaging data
    Patent number: 9147246
    Abstract: A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: September 29, 2015
    Assignees: Ben-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
    Inventors: Alon Friedman, Yoash Chassidim, Ofer Prager, Ilan Shelef
  • Elongated body for deployment in a heart
    Patent number: 9131928
    Abstract: Coronary sinus ring apparatus, including an elongated body for deployment in a coronary sinus, an aperture in a long side of the body, at least a partial lumen extending from one end of the elongated body to at least the aperture, and a guide within the elongated body positioned and shaped to guide an element inserted along the lumen to the aperture. Apparatus for treating a heart, including a delivery tube sized for and adapted for insertion into a body, a sharp tip adapted to be pushed through cardiac muscle, an elongate tensioning element, and a foldable anchor adapted to couple the elongate tension element to cardiac muscle tissue, wherein the delivery tube encloses one or both of the elongate tensioning element and the foldable anchor. Related apparatus is also described.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: September 15, 2015
    Assignee: Mor Research Applications Ltd.
    Inventors: Amnon Zlotnick, Henry M. Israel, Boaz Harari
  • Grain fraction endosperm recovery system
    Patent number: 9079184
    Abstract: Generally, a dry-wet grain fractionation system which provides a dry mill process (26) for the production of grain fractions (14) (15) (16) and a wet mill process (18) for the production of purified bran (19), endosperm (20) and germ (21) from the mixture of grain particles in a grain fraction (14) (15) or (16) or combinations thereof. Specifically, a dry-wet grain fractionation system for production of corn germ (21) having increased protein and oil content and an endosperm (20) having increased starch and sugar content.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: July 14, 2015
    Assignee: MOR Technology, LLC
    Inventor: Daniel L. Claycamp
  • Accommodating intraocular lens assembly
    Patent number: 9034035
    Abstract: An accommodating intraocular lens (AIOL) assembly (10) including an optics assembly (12) including an inflatable member (14), and characterized by an extra-capsular-bag interface structure (16) for interfacing with ocular structure of an eye external to a capsular bag for implanting the AIOL (10) outside the capsular bag, the extra-capsular-bag interface structure (16) including a less-rigid portion (18) and a more-rigid portion (20) that define a volume therebetween which is at least partially filled with a fluid (22) and which is in fluid communication with the inflatable member (14) via at least one conduit (24), and wherein the less-rigid portion (18) is responsive to movement of the ocular structure to apply a pumping force on the fluid (22) to cause the fluid (22) to flow via the at least one conduit (24) to the inflatable member (14) so as to change the optical power of the optics assembly (12).
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: May 19, 2015
    Assignee: Mor Research Applications Ltd.
    Inventors: Nir Betser, Ehud Assia
  • FGL-2 prothrombinase as a diagnostic tool for malignancy
    Patent number: 9023609
    Abstract: The present invention reveals a strong correlation between FGL-2 prothrombinase activity levels and the presence of a malignant proliferative disorder in a subject. Thus, the present invention provides FGL-2 prothrombinase activity as a diagnostic tool for malignancy.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: May 5, 2015
    Assignees: Mor Research Applications Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Aida Inbal, Esther Rabizadeh
  • Appliance bracket
    Patent number: 9016641
    Abstract: A bracket having a base having a mounting plate with upstanding flanges on opposite sides. The flanges each include an upper notch and a lower notch oppositely located therefrom. The lower notches are adapted for receiving a second member. An adapter has a second mounting plate and upstanding flanges extending from opposite sides of the second mounting plate. The flanges carry the first and second members. The first member is biased laterally by a spring to a fully outward position. The first member is movable between the fully outward position and an inward position. The second member is fixed laterally with respect to the flanges on the adapter. The upper and lower notches are positioned so their respective openings are closer than the outermost portions of the first and second members when the first member is in its fully outward position.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: April 28, 2015
    Assignee: MOR/ryde International, Inc.
    Inventors: Jon Kauffman, Barry Ousley
  • MIDDLE EAR PROSTHESIS
    Publication number: 20150039088
    Abstract: A middle ear prosthesis (40) is provided for mounting in the middle ear (4). The middle ear prosthesis comprises a shaft (42) having a distal end configured for the introduction into the inner ear (8) through an aperture (30) formed in a footplate (23) of a stapes bone and in a membrane of an oval window of the inner ear, by moving the shaft in an introduction direction, the shaft being configured for transmitting sound wave vibrations to the inner ear. The prosthesis further comprises a coupling portion (46), for coupling, the shaft to at least one of the ossicles (17) so as to allow transmitting thereby sound wave vibrations from the ossicles to the shaft; and a stop member (48) spaced from the distal end of the shaft and configured for bearing against the remaining portions thereby limiting the movement of the shaft in the introduction direction.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 5, 2015
    Applicant: MOR RESEARCH APPLICATIONS LTD
    Inventor: Salim Mazzawi
  • Diagnosing, prognosing and monitoring multiple sclerosis
    Patent number: 8945935
    Abstract: The present invention provides a system and method for diagnosing, monitoring or prognosing Multiple Sclerosis at different stages as well as affording the prediction of disease activity and response to a treatment regimen, using at least one sensor comprising carbon nanotubes or metal nanoparticles, each coated with various organic coatings in conjunction with a pattern recognition algorithm.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: February 3, 2015
    Assignees: Technion Research & Development Foundation Ltd., Mor Research Applications Ltd., Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Hossam Haick, Ariel Miller
  • Methods and compositions for inhibiting the nuclear factor ?B pathway
    Patent number: 8945632
    Abstract: The current invention provides therapeutic methods which include inhibition of nuclear factor ?b pathway in a cell based on the discovery of an active fraction of a plant extract termed NUP or a composition which includes NUP. NUP is used in treating and managing different diseases such as cancer, inflammation, and virus infections.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: February 3, 2015
    Assignees: Ben Gurion University of the Negev R&D Authority, Mor Research Applications Ltd.
    Inventors: Avi Golan, Jacob Gopas, Janet Ozer, Nadav Eisner, Adelbert Bacher, Wolfgang Eisenreich, Elena Ostrozhenkova, Hila Winer
  • Red microalgae expressing exogenous polypeptides and methods of generating and utilizing same
    Patent number: 8936930
    Abstract: A method of transforming red microalgae is provided. The method is effected by: (i) culturing red microalgae cells under predetermined light/dilution conditions to thereby generate competent red microalgae cells; and (ii) introducing at least one exogenous polynucleotide into said competent red microalgae cells, thereby transforming the red microalgae.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: January 20, 2015
    Assignees: Ben-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
    Inventors: Shoshana Arad, Miri Lapidot, Yacob Weinstein, Ron Dagan
  • Beard cover
    Patent number: D725827
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: March 31, 2015
    Assignee: Mor-Dall Enterprises, Inc.
    Inventor: Kristine L. Boley-Morse