Abstract: This invention features methods and apparatus for performing nucleic acid hybridization and amplification processes on a support. Such methods and apparatus are useful for synthesizing nucleic acid and detecting target nucleic acid for diagnostics and therapeutics.
Type:
Grant
Filed:
May 29, 1997
Date of Patent:
July 18, 2000
Assignees:
Mosaic Technologies, Inc., Whitehead Institute for Biomedical Research
Abstract: This invention features methods, apparatus and kits for performing nucleic acid hybridization and amplification reactions on a support. Such methods and apparatus are useful in diagnostic and therapeutic processes for synthesizing nucleic acid and detecting target nucleic acids in a sample.
Type:
Grant
Filed:
February 14, 1997
Date of Patent:
May 9, 2000
Assignee:
Mosaic Technologies
Inventors:
Christopher P. Adams, Truett C. Boles, Andrew R. Muir, Stephen J. Kron
Abstract: Disclosed is a polymerizable complex containing a covalently attached nucleic acid molecule which, under appropriate conditions, is capable of copolymerization with a second polymerizable ethylene-containing monomer unit to form a polymerized layer. The polymerized layer containing attached nucleic acid is useful in a variety of contexts including, for example, hybridization assays. The polymerized layer containing the covalently attached nucleic acid molecule can be formed into a variety of shapes, or attached to a formed material through appropriate chemistry.
Type:
Grant
Filed:
March 5, 1997
Date of Patent:
August 3, 1999
Assignee:
Mosaic Technologies, Inc.
Inventors:
T. Christian Boles, Stephen J. Kron, Christopher P. Adams
Abstract: This invention features methods and apparatus for performing nucleic acid hybridization and amplification processes on a support. Such methods and apparatus are useful for synthesizing nucleic acid and detecting target nucleic acid for diagnostics and therapeutics.
Type:
Grant
Filed:
August 3, 1994
Date of Patent:
June 24, 1997
Assignees:
Mosaic Technologies, Inc., Whitehead Institute for Biomedical Research
Inventors:
Christopher P. Adams, Stephen Joseph Kron