Abstract: The present invention relates to amino acid sequences that are directed against Interleukin-23 (IL-23). The amino acid sequences of the present invention comprise two NANOBODIES® against IL-23 and one NANOBODY® against serum albumin, linked by two linkers (9GS linkers). In particular, the invention relates to the amino acid sequences of SEQ ID NO: 2 and SEQ ID NO: 3 (listed in Table 1 and FIG. 1) (also referred to herein as “anti-IL 23 polypeptides of the invention”).

Abstract: An apparatus (100) includes: an outer shell (211); an inner vessel (212) disposed within the outer shell; a cold head (260) having a first stage (261) disposed within the outer shell, and having a second stage (262) for contacting an interior of the inner vessel; a vent (215) extending from the interior of the inner vessel to the exterior of the outer shell; first and second heat exchangers (302a, 302b); a first thermal shield (213) disposed between the inner vessel and the outer shell; and a second thermal shield (214) disposed between the inner vessel and the first thermal shield. The first thermal shield is thermally connected to the first stage of the cold head and the first heat exchanger and is thermally isolated from the inner vessel and outer shell. The second thermal shield is thermally connected to the second heat exchanger and is thermally isolated from the inner vessel, outer shell, first thermal shield, and cold head.

Abstract: Systems and methods for secure mobile transactions are disclosed.

Abstract: The present invention relates to an assessing system, an assessing method and a computer program for assessing a heart rate of a subject. It finds application in categorizing a physiological response as a condition, in particular in the diagnosis of pathological tachycardia and bradycardia. The assessing system comprises a photoplethysmography (PPG) signal providing unit (10); a motion signal providing unit (20); a parameter providing unit (30) for providing a subject specific parameter; a heart rate determination unit (40); a resting period determination unit (50); an abnormality determination unit (80) for determining an abnormality of the heart rate during the resting period; and an assessing unit (90) for assessing the determined abnormality based on the subject specific parameter. The invention provides a system and a method, which allow for a more reliable assessment of a heart rate of a subject based on a PPG signal of the subject.

Abstract: A hair cutting device includes a cutter having a guard moveable relative a blade carrier to vary a cutting length within a cutting length range. The cutter has an actuator moveable between first and second positions to move a follower element and the guard to vary the cutting length between two extreme length settings. The cutter is pivotable relative a housing of the cutting device between an open position and a closed position for cutting. The follower element is configured to cooperate with the actuator so that, when the cutter is in the open position with the follower element and guard in the first position, but the actuator is in the second position, pivoting movement of the cutter to the closed position causes the actuator to drive the follower element and the guard to the second position.

Abstract: Methods, apparatuses, and computer program products are disclosed for securely migrating data between devices. An example method includes receiving a request at a first time for data migration between a first user device and a second user device each associated with a first user. The method further includes retrieving a baseline attribute dataset associated with the first user generated before the first time and generating a first attribute dataset associated with the first user. The method includes authenticating a session between the first user device and the second user device at the first time and causing data transfer between the first user device and the second user device. The method further includes generating a second attribute dataset associated with the first user at a second time after the first time and authenticating the session at the second time based on the first attribute dataset and the second attribute dataset.

Abstract: Deposited math based currency (“MBC”) is received at a financial institution. A processor of the financial institution receives a deposit request from a customer via a computing device. The request includes a customer private key associated with an amount of MBC to be deposited. The processor creates a first private and public key pair to receive the amount of MBC to be deposited. The processor initiates a transaction in the amount of MBC to be deposited to the first private and public key pair from the customer based on the customer private key. The processor updates a ledger to indicate that the amount of MBC to be deposited was received and is associated with an account of the customer. The ledger includes information relating to a plurality of MBC accounts associated with a plurality of customers. The processor stores the first private and public key pair in a pooled database.

Abstract: The invention provides a waveguide element (1000) comprising a first face (1001) and a second face (1002) with radiation transmissive material (1005) configured between the first face (1001) and the second face (1002), wherein the radiation transmissive material (1005) is transmissive for UV radiation, wherein the radiation transmissive material (1005) is a matrix material for a phase (1010) of another composition than the radiation transmissive material (1005), wherein the phase (1010) is available in the matrix as regions (1110) with the regions (1110) having mean particle radii (r1) selected from the range of 50-1500 nm and having an average region concentration selected from the range of 1*104-1.5*108/mm3 of the radiation transmissive material (1005).

Abstract: A method for separately registering a user and a mobile device for use of a mobile wallet account includes registering, by a registration terminal of a mobile wallet provider, a user for use of the mobile wallet account, including assigning one or more user-provided settings to the mobile wallet account. The method also includes receiving, by a computing system of the mobile wallet provider, a request from a mobile device to register the mobile device for use as a mobile wallet, identifying, by the computing system, the mobile wallet account of the registered user based on the request, and registering, by the computing system, the mobile device for use of the identified mobile wallet account, including associating the one or more user-provided settings with use of the mobile device.

Abstract: Systems and methods are provided for integrated healthcare management. The systems and methods include establishing a medical record data, accessing information about a treatment related to the medical record data, obtaining biometric data related to the treatment, processing the biometric data, determining whether the treatment is appropriate with respect to the biometric data, in response to the treatment being appropriate with respect to the biometric data, administering medication, and in response the treatment not being appropriate with respect to the biometric data, determining a new treatment, and administering new medication based on the new treatment.

Abstract: A method for providing a notification of applications that relate to a business process is provided. The method includes collecting identification data that relates to each of a plurality of applications connected to the at least one processor; storing the identification data; receiving a user request for information that includes a list of first applications that relate to the business process; analyzing the identification data to determine whether each respective one of the plurality of applications is to be included in the list; and generating the list based on a result of the analyzing and notifying the user of the list. The method also includes collecting network data that relates to each of the plurality of applications; storing the network data; and analyzing the network data to determine whether each respective one of the plurality of applications is to be added to the list.

Abstract: A method for capturing documentation information is provided. The method includes: receiving an input that relates to a regulatory body; identifying at least one jurisdiction that applies regulations in connection with the regulatory body; extracting, from a source database, at least one publication that includes information that relates to the regulations; formatting the regulations-related information from the extracted publications into a predetermined format; and outputting the formatted information to a computer display.

Abstract: A system includes a radiation source, first and second phased arrays, and a detector. The first and second phased arrays include optical elements, a plurality of ports, waveguides, and phase modulators. The optical elements radiate radiation waves. The waveguides guide radiation from a port of the plurality of ports to the optical elements. Phase modulators adjust phases of the radiation waves. One or both of the first and second phased arrays form a first beam and/or a second beam of radiation directed toward a target structure based on the port coupled to the radiation source. The detector receives radiation scattered by the target structure and generates a measurement signal based on the received radiation.

Abstract: Examples described herein relate to apparatus and methods for managing rewards for a customer of a financial institution, including but not limited to, determining a transaction pattern associated with transactions made by the customer, determining a deviation from the transaction pattern, determining an event associated with the customer based on the deviation, and determining rewards that correspond to the event for the customer.

Abstract: An ECG controller for an ECG device is connectable to a base ECG lead system (e.g., a 12-lead system) whereby the ECG controller implements an ECG waveform morphology based and ECG lead redundancy based detection and classification of any cable interchange (e.g., a limb cable interchange or a precordial cable interchange) between the ECG controller and the base ECG lead system. Alternatively, the ECG controller is further connectable to a sub-base ECG lead system (e.g., a limb only-lead system or a limited precordial-lead system) whereby the ECG controller implements an ECG waveform morphology based detection and classification of any cable interchange (e.g., a limb cable interchange or a precordial cable interchange) between the electrode interface and the sub-base ECG lead system.

Abstract: A computer-implemented method for analyzing a user session within an online environment includes receiving, by a path analysis computer system, usage data related to a user session within an online environment, wherein the usage data includes a plurality of events occurring within the user session, and generating, by the path analysis computer system, a plurality of user paths for the user session based on the usage data, including generating a separate user path beginning with each of the plurality of events. Each of the user paths is generated by selecting one of the plurality of events as a starting event, and arranging the plurality of events subsequent to the starting event in order of occurrence, such that the user path includes the starting event and each of the subsequent events up to and including a final event.

Abstract: Systems and methods for device-agnostic, multi-factor network authentication are disclosed. In some embodiments, a wireless network connection can authenticate a device over secure authentication means with a certificate that confirms a device identity. After authenticating the device, a user can be prompted to provide credentials in a captive portal. The captive portal can be inaccessible to devices that have not already authenticated using a certificate. After providing approved credentials to the captive portal, the user can access the network. This embodiment and additional embodiments are readily integrated into private wireless networks and others.

Abstract: A process is disclosed for converting cellulose to nanocellulose. The process comprises dissolving a cellulose feedstock in an inorganic molten salt solvent medium. The solvent medium is substantially proton free. The solvent medium may contain a proton scavenger. The process is carried out at relatively low temperatures, and requires little input of mechanical energy.

Abstract: An apparatus for ultrasound irradiation of a body part (208) includes a first ultrasound transducer (216), and a second ultrasound transducer (212) mounted oppositely, and is configured: a) such that at least two ultrasound receiving elements, for determining a relative orientation of the first to the second transducer, are attached to the first transducer; b) for a beam, from the first transducer, causing cavitation, and/or bubble destruction of systemically circulating microbubbles, within the body part; or c) both with the attached elements and for the causing. The apparatus registers, with said first transducer, the second transducer, by using as a reference respectively the features a) and/or b).

Abstract: Examples described herein relate to apparatuses and methods for providing automated advising services to a customer of a provider institution, including but not limited to a provider institution computing system determining a goal of the customer based on a user input of the customer, generating a set of sub-goals for the goal, determining a current status of the customer relating to the sub-goals and the goal, determining whether the current status of the customer meets any sub-goals and a projected status of the customer indicating whether the customer is projected to meet the goal, and sending a notification to a user device of the customer notifying the customer of a completion state of the goal based on at least one of the sub-goals met by the current status of the customer and whether the customer is projected to meet the goal.