Abstract: Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double-stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented with nanopore (including micropore) detection systems.
Type:
Application
Filed:
October 1, 2008
Publication date:
April 16, 2009
Applicant:
NABsys, Inc.
Inventors:
John Oliver, Barrett Bready, Peter Goldstein, Franco Preparata