Patents Assigned to Nankai University
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Patent number: 12257615Abstract: A stacked circulatable microbial electrochemical reactor and a degradation method of petroleum hydrocarbon contaminated soil are provided, which belong to the field of microbial electrochemical soil remediation. The stacked circulatable microbial electrochemical reactor of the present disclosure expands influence range of anodes by a stacked microbial electrochemical system, accelerates the movement of the petroleum hydrocarbon molecules in the contaminated soil by a water circulation system, and improves the mass transfer capacity of soil, thereby increasing the degradation efficiency of petroleum hydrocarbon in the contaminated soil with microbial electrochemical technology from different aspects. The degradation method of petroleum hydrocarbon contaminated soil is provided. The degradation method of the present disclosure is simple in operation and has a high degradation efficiency of petroleum hydrocarbon in contaminated soil.Type: GrantFiled: April 8, 2021Date of Patent: March 25, 2025Assignee: Nankai UniversityInventors: Qixing Zhou, Tian Li, Xin Wang
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Patent number: 12237470Abstract: The invention belongs to the technical field of batteries, and discloses a phosphate-based flame-retardant electrolyte and a lithium-metal battery, and the phosphate-based flame-retardant electrolyte consists of a lithium salt, a phosphate solvent and a diluent. According to the invention, dimethyl (2-methoxyethoxy)methylphosphonate or diethyl (2-methoxyethoxy)methylphosphonate is used as a novel phosphate solvent, an electrolyte system with local high salt concentration is adopted, most phosphate solvent molecules are complexed with Li+ at the local high salt concentration by adjusting dosages of the lithium salt, the phosphate solvent and the diluent, so almost none of free solvent molecules exist, thus inhibiting irreversible decomposition of phosphate molecules on a surface of a li-anode, and meanwhile, the flame retardancy of the phosphate solvent greatly improves the safety of the lithium-metal battery.Type: GrantFiled: July 20, 2023Date of Patent: February 25, 2025Assignee: Nankai UniversityInventors: Jun Chen, Chunyu Zheng, Yuankun Wang, Yunpeng Hou, Zhenhua Yan, Haixia Li, Qing Zhao
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Patent number: 12215279Abstract: A method for administering a composition for exploiting natural gas hydrates. The method includes the following steps: injecting the reagent A into the tube A; injecting the reagent B into the tube B; stretching the tube A and the tube B into a hydrate reservoir by using a reagent injection instrument; regulating a flow rate according to a proportion of each component; allowing the reagents to react at a preset reservoir position; and allowing water in the reservoir to participate in the reaction at the same time, wherein a reaction product is used for supporting the reservoir.Type: GrantFiled: July 21, 2023Date of Patent: February 4, 2025Assignee: Nankai UniversityInventors: Xiaohang Liu, Annan Guo, Peng Zhao, Xiaoyang Li, Jinqiang Liang, Wei Huang, Yongqin Zhang
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Publication number: 20250019736Abstract: The present disclosure provides a microbial electrolysis cell (MEC) reactor and a rapid test method for a biochemical oxygen demand (BOD) of organic wastewater, and relates to the technical field of analysis and detection. In the present disclosure, an efficient MEC reactor is constructed based on a MEC sensing technology; meanwhile, combined with a continuous short-cycle test method and a supporting data calculation method, a rapid test method is obtained, and can be applied to various types of complex organic wastewater that does not have a biologically toxic substance and is greater than 5 mg BOD/L. After three cycles of test, last two stable cycles are taken to allow calculation; at the same time, a resulting curve is divided into multiple segments according to changes in main components of a degraded organic matter in different periods to allow segmented weighted calculations.Type: ApplicationFiled: December 11, 2023Publication date: January 16, 2025Applicant: Nankai UniversityInventors: Xin WANG, Chengmei LIAO, Ziyuan WANG, Nan LI
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Patent number: 12187811Abstract: Provided are a cyclic peptide compound simulating a natural product structure and a method for preparation thereof. The method is: the compound of formula I, a divalent palladium catalyst, and a silver salt undergoing an intramolecular arylation in a solvent under heating and stirring to construct a cyclic peptide, to generate the compound of formula II, in which the arylation sites are diverse, and can be extended to the side chain ?-position methyl or methylene of the majority hydrophobic amino acids to perform intramolecular arylation, thus overcoming the previous defect of the restriction of the types of selectable amino acids, and effectively constructing a novel aromatic ring-supported cyclic peptide compound. The aromatic ring support structure forms a novel 3D structure similar to a natural product, and provide a very favorable support for the subsequent construction of a cyclic peptide molecular library and high-throughput drug screening.Type: GrantFiled: June 21, 2019Date of Patent: January 7, 2025Assignee: Nankai UniversityInventors: Gong Chen, Bo Li, Xinghua Li, Boyang Han, Gang He
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Patent number: 12098414Abstract: It is provided a monitoring reactor and a method for using the same, belonging to microbiologic electrochemical early-warning technology. The monitoring reactor enriches microorganisms therein before use, and consumes the organic matter. When the organic matter in the monitoring reactor is consumed completely, i.e. the microorganisms are in a starved state, the monitoring reactor is placed in a system to be monitored for monitoring, thereby avoiding the interference of the organic matter in the soil in the monitoring reactor to the electrical signal and improving the monitoring accuracy. Furthermore, since the electrical signal in the monitoring reactor is conducted through the electricigens, the process of generating electricity of the electricigens is a process of growth and propagation of microorganism. This process is less affected by the monitored environment. Therefore, the signal output process is stable, without swell and sag of the electrical signal.Type: GrantFiled: March 30, 2021Date of Patent: September 24, 2024Assignee: Nankai UniversityInventors: Tian Li, Qixing Zhou
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Patent number: 12091340Abstract: The present disclosure relates to the technical field of microbial electrochemical technology, in particular to a graphene-magnetite conductive skeleton electrode, a preparation method and application thereof, and a method for treating petrochemical wastewater. In the present disclosure, the surface roughness of the graphite rod electrode can be increased by the conductive skeleton modified on the surface of the graphite rod electrode, which is beneficial to the enrichment of microorganisms. The increase in the load of microorganisms will mean the amount of electroactive microorganisms will also increase, which will further improve the electron transfer ability, and because the material of the modified layer is a conductive material, it is also more conducive to the transfer of electrons; at the same time, the conductive skeleton modified on the surface of graphite rod electrode can also further enhance the transmission distance of electrons because of the skeleton constructed.Type: GrantFiled: September 13, 2021Date of Patent: September 17, 2024Assignee: Nankai UniversityInventors: Qixing Zhou, Ruixiang Li, Tian Li, Xiaolin Zhang
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Patent number: 11986380Abstract: Disclosed is a bending-resistant nerve catheter and a preparation method and application thereof, and relates to the technical field of tissue engineering materials. The catheter of the present application includes an inner layer, a middle layer and an outer layer, and each layer uses raw materials of biodegradable polymers; among them, the inner layer includes a smooth surface inner layer, an oriented microchannel inner layer or a fibrous inner layer, the middle layer is a fibrous middle layer with crossing angles, the middle layer is prepared by entangling micron fibers with a certain angular arrangement, and the outer layer is made of randomly entangled polymer fibers and is tightly bonded to the middle layer.Type: GrantFiled: May 1, 2023Date of Patent: May 21, 2024Assignees: Neosheng (Tianjin) Biotechnology Co., Ltd, Nankai UniversityInventors: Meifeng Zhu, Deling Kong, Xianhao Dong, Guangzhou Song
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Patent number: 11908037Abstract: The present disclosure provides a method and system for large-capacity image steganography and recovery based on an invertible neural networks. The method is intended to embed one or more hidden images into a single host image, and recover all the hidden images from a stego image. The method designs an image steganography model that supports bidirectional mapping. The model includes cascaded invertible modules containing a host branch and a hidden branch. A hidden image is embedded into a host image through forward mapping to form a stego image, and the host image and the hidden image are separated and recovered from the single stego image through reverse mapping.Type: GrantFiled: June 18, 2021Date of Patent: February 20, 2024Assignee: Nankai UniversityInventors: Shaoping Lu, Rong Wang, Tao Zhong
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Patent number: 11865595Abstract: A device for wholly treating urban and rural mixed household refuse at low temperature on site is provided. The device includes a vibration sieving and crushing system, a magnetic separator, conveyor belts, a magnetic pulse mineralization reactor and a tail gas purifying device. By using the device, urban and rural mixed household refuse is continuously fed; the mixed household refuse is sieved by the vibrating sieve according to viscosity, weight and size; nonferrous metal is sieved through a magnetic field; and organic substances are conveyed to the magnetic pulse mineralization mixed household refuse treatment device for terminal treatment. So, efficient reduction and harmlessness of the organic substances in the mixed household refuse are realized, and the pollution of organic wastes on the environment is effectively eliminated.Type: GrantFiled: August 24, 2021Date of Patent: January 9, 2024Assignees: Nankai University, Chifeng Environmental Science Research Institute, Tianjin Shangyusheng Technology Dev., Co., Ltd.Inventors: Weizun Li, Peng Ji, Tianliang Xia, Yuandong Xia, Ruifeng Zhang, Xunwei Wang, Mingyan Yu
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Publication number: 20240005440Abstract: The present disclosure provides a method and system for large-capacity image steganography and recovery based on an invertible neural networks. The method is intended to embed one or more hidden images into a single host image, and recover all the hidden images from a stego image. The method designs an image steganography model that supports bidirectional mapping. The model includes cascaded invertible modules containing a host branch and a hidden branch. A hidden image is embedded into a host image through forward mapping to form a stego image, and the host image and the hidden image are separated and recovered from the single stego image through reverse mapping.Type: ApplicationFiled: June 18, 2021Publication date: January 4, 2024Applicant: Nankai UniversityInventors: Shaoping Lu, Rong Wang, Tao Zhong
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Patent number: 11760923Abstract: The present invention relates to a reagent for exploiting natural gas hydrates, which includes a regent A and a regent B. The reagent A is PEG400-polyurethane prepolymer; the reagent B includes PEG400 and an initiator; and a volume ratio of the PEG400-polyurethane prepolymer, the PEG400 and the initiator is (1-3000):(1-1000):(1-2000). The reagent of the present invention has excellent performance and high stability, and can effectively “replace” the “water” of the natural gas hydrate; and moreover, the reaction is exothermic reaction to effectively increase the reaction rate, which reduces the energy loss on the one hand, and reduces the blockage of a gas passage caused by the secondary generation of the natural gas hydrates in a low-temperature high-pressure pipeline during transferring on the other hand.Type: GrantFiled: December 22, 2022Date of Patent: September 19, 2023Assignees: Nankai University, Guangzhou Marine Geological Survey, Institute of Exploration Technology, Chinese Academy of Geological SciencesInventors: Xiaohang Liu, Annan Guo, Peng Zhao, Xiaoyang Li, Jinqiang Liang, Wei Huang, Yongqin Zhang
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Publication number: 20230144262Abstract: The present disclosure relates to the technical field of terahertz (THz) wave measurement and relates to a photo-thermo-acoustic mechanism-based power measurement apparatus and measurement method for a terahertz wave at room temperature. The apparatus includes a terahertz wave power modulation component, a photo-thermo-acoustic conversion device, and an acoustic wave measurement component. In the present disclosure, the THz absorbing substance having a photo-thermo-acoustic effect is used as the photo-thermo-acoustic conversion device. A power-modulated terahertz wave is converted into an acoustic wave pulse by means of the photo-thermo-acoustic mechanism. The acoustic wave measurement component measures the acoustic wave pulse. A peak-to-peak value of a pulse of the measured acoustic wave is proportional to the power of the terahertz wave, thereby implementing the fast broadband measurement of the terahertz wave power at room temperature.Type: ApplicationFiled: November 2, 2022Publication date: May 11, 2023Applicant: Nankai UniversityInventors: Weiwei LIU, Tingyuan WANG, Nan ZHANG, Lanjun GUO
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Patent number: 11543564Abstract: The present disclosure provides a metalens array and a spatial positioning method based on the metalens array. The metalens array includes at least two metalenses, each of the metalenses comprises a plurality of prism cells, each of the prism cells comprises a silicon dioxide substrate and a titanium oxide prism placed on the silicon dioxide substrate, and the plurality of prism cells are arranged periodically.Type: GrantFiled: September 25, 2020Date of Patent: January 3, 2023Assignee: Nankai UniversityInventors: Shuqi Chen, Wenwei Liu, Dina Ma, Hua Cheng, Jianguo Tian
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Patent number: 11505800Abstract: A method for improving a bio-coupling efficiency between a protein and a nucleic acid based on an ?-helix handle includes the following steps. First, the handle carrying the non-natural amino acid (H-tag) is designed. Then, a recombinant expression plasmid encoding a fusion protein containing the H-tag and the protein to be tested is constructed. Subsequently, the fusion recombinant protein containing the non-natural amino acid in the H-tag is expressed and purified. Finally, the non-natural amino acid in the H-tag-fused protein and the coupling group on the nucleic acid substrate are efficiently connected by click chemistry. Thea-helix handle is used to provide a controllable reaction condition on the protein surface for the non-natural amino acid, avoiding the complex structure, charge and polar nanoenvironment around the surface of the protein to be tested.Type: GrantFiled: September 23, 2019Date of Patent: November 22, 2022Assignee: Nankai UniversityInventors: Zhongbo Yu, Xu Li, Xiaofeng Ma, Lihua Qu, Wei Huang
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Publication number: 20220315623Abstract: Provided are a cyclic peptide compound simulating a natural product structure- and a method for preparation thereof. The method is: the compound of formula I, a divalent palladium catalyst, and a silver salt undergoing an intramolecular arylation in a solvent under heating and stirring to construct a cyclic peptide, to generate the compound of formula II, in which the arylation sites are diverse, and can be extended to the side chain ?-position methyl or methylene of the majority hydrophobic amino acids to perform intramolecular arylation, thus overcoming the previous defect of the restriction of the types of selectable amino acids, and effectively constructing a novel aromatic ring-supported cyclic peptide compound. The aromatic ring support structure can form a novel 3D structure similar to a natural product, and provide a very favorable support for the subsequent construction of a cyclic peptide molecular library and high-throughput drug screening.Type: ApplicationFiled: June 21, 2019Publication date: October 6, 2022Applicant: Nankai UniversityInventors: Gong CHEN, Bo LI, Xinghua LI, Boyang HAN, Gang HE
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Publication number: 20220001076Abstract: The invention relates to the complex of synthetic polymer and natural extracellular matrix for vascular grafts and their preparation methods. The components of biodegradable synthetic polymer in the preparation process can be chosen with different material proportions. The scaffolds with different fiber diameters, different fiber arrangements, different pore sizes and different pore structures can be prepared by electro-spinning, wet-spinning, melt-spinning, 3D printing, pouring, phase separation, particle leaching and other technologies. Among them, the natural extracellular matrix components come from a wide range of sources such as vascular tissues from different kinds of animals including arteries and veins of pigs and cattle or vascular tissues from human donors including umbilical cord vessels, etc. And its composition and content can be flexibly adjusted according to the demand.Type: ApplicationFiled: June 1, 2019Publication date: January 6, 2022Applicant: Nankai UniversityInventors: Deling Kong, Xianhao Dong, Meifeng Zhu
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Publication number: 20210374227Abstract: The present disclosure discloses a trusted execution environment (TEE)-based password management method and system. This method assumes a hardware trusted environment on a mobile end. A user authorizes the hardware trusted environment, and an independent operating system in the trusted environment automatically performs password management operations. The TEE registers an independent strong password for each account, and stores a correspondence between accounts and applications (or websites) in a hardware security zone. When an application requests login, an account list corresponding to the application is returned for a user to select. Through point-to-point encrypted transmission, different trusted devices can synchronize stored password information. In addition, a trusted mobile end can manage applications (or websites) on other devices without a TEE such as laptops.Type: ApplicationFiled: December 16, 2020Publication date: December 2, 2021Applicant: Nankai UniversityInventors: Mingming CHENG, Yuchao Gu
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Publication number: 20210332372Abstract: A method for improving a bio-coupling efficiency between a protein and a nucleic acid based on an ?-helix handle includes the following steps. First, the handle carrying the non-natural amino acid (H-tag) is designed. Then, a recombinant expression plasmid encoding a fusion protein containing the H-tag and the protein to be tested is constructed. Subsequently, the fusion recombinant protein containing the non-natural amino acid in the H-tag is expressed and purified. Finally, the non-natural amino acid in the H-tag-fused protein and the coupling group on the nucleic acid substrate are efficiently connected by click chemistry. Thea-helix handle is used to provide a controllable reaction condition on the protein surface for the non-natural amino acid, avoiding the complex structure, charge and polar nanoenvironment around the surface of the protein to be tested.Type: ApplicationFiled: September 23, 2019Publication date: October 28, 2021Applicant: Nankai UniversityInventors: Zhongbo Yu, Xu Li, Xiaofeng Ma, Lihua Qu, Wei Huang
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Publication number: 20210206731Abstract: The present invention belongs to the technical field of pesticides, particularly relates to sulfonyl-structure-containing triazinone derivatives, their preparation methods, and their uses in insect killing and/or bacterium killing. The sulfonyl-structure-containing triazinone derivatives are compounds represented by formula (Ia) or (Ib). The sulfonyl-structure-containing triazinone derivatives provided in the present invention exhibit outstanding insecticidal activity as well as bactericidal activity.Type: ApplicationFiled: September 21, 2017Publication date: July 8, 2021Applicant: Nankai UniversityInventors: Qingmin Wang, Hongjian Song, Yan Yang, Yuxiu Liu, Ziwen Wang