Abstract: A device for wholly treating urban and rural mixed household refuse at low temperature on site is provided. The device includes a vibration sieving and crushing system, a magnetic separator, conveyor belts, a magnetic pulse mineralization reactor and a tail gas purifying device. By using the device, urban and rural mixed household refuse is continuously fed; the mixed household refuse is sieved by the vibrating sieve according to viscosity, weight and size; nonferrous metal is sieved through a magnetic field; and organic substances are conveyed to the magnetic pulse mineralization mixed household refuse treatment device for terminal treatment. So, efficient reduction and harmlessness of the organic substances in the mixed household refuse are realized, and the pollution of organic wastes on the environment is effectively eliminated.

Abstract: The present disclosure provides a method and system for large-capacity image steganography and recovery based on an invertible neural networks. The method is intended to embed one or more hidden images into a single host image, and recover all the hidden images from a stego image. The method designs an image steganography model that supports bidirectional mapping. The model includes cascaded invertible modules containing a host branch and a hidden branch. A hidden image is embedded into a host image through forward mapping to form a stego image, and the host image and the hidden image are separated and recovered from the single stego image through reverse mapping.

Abstract: The present disclosure relates to the technical field of medicine, in particular to use of a prostaglandin E2 (PGE2)-primed mesenchymal stem cell (MSC) product in preparation of a drug for treating lung injury (LI). A preparation method of the PGE2-primed MSC product includes conducting mixed culture on PGE2 and MSCs to obtain the PGE2-primed MSC product. The PGE2 and the MSCs are subjected to the mixed culture to enhance functions of the MSCs, promote migration of the MSCs to injury sites, strengthen anti-inflammatory effects of the MSCs, facilitate MSC proliferation, effectively relieve various lung injuries, and accelerate regeneration of injured alveolar epithelial cells. The drug prepared from the PGE2-primed MSC product provided by the present disclosure can effectively relieve LI and accelerate the regeneration of injured alveolar epithelial cells, and a remarkable treatment effect is obtained.

Abstract: A method for preparing a pyridine compound substituted with trifluoromethylthio, difluoromethylthio or trifluoromethyl in the meta position is provided, which includes S1. in a glove box filled with nitrogen, adding a catalyst, a solvent, pinacolborane, and pyridine to a reaction flask, stirring the mixture, and performing a reaction at 40-100° C. for 2-12 hours to obtain dihydropyridine; S2. adding a trifluoromethylthio reagent, a difluoromethylthio reagent, or a trifluoromethyl reagent to the reaction flask, stirring the mixture, and performing a reaction at room temperature to 80° C. for 2-12 hours to obtain trifluoromethylthio-, difluoromethylthio- or trifluoromethyl-substituted dihydropyridine; and S3.

Abstract: The present application provides a lithium niobate having a p-type nanowire region or an n-type nanowire region and a method for preparing the same. The method includes heating and then cooling a multi-domain lithium niobate crystal to confine hydrogen ions of the multi-domain lithium niobate crystal in domain wall regions; and poling the multi-domain lithium niobate crystal that has been heated by applying a voltage, to reverse a direction of polarization of one or more domains of the multi-domain lithium niobate crystal. The lithium niobate includes a lithium niobate crystal and a p-type nanowire region or an n-type nanowire region located in the lithium niobate crystal and adjacent to a surface of the lithium niobate crystal. The present application also provides a method for converting the charge carrier type of the lithium niobate nanowire region.

Abstract: A method for preparing a pyridine compound substituted with trifluoromethylthio, difluoromethylthio or trifluoromethyl in the meta position is provided, which includes S1. in a glove box filled with nitrogen, adding a catalyst, a solvent, pinacolborane, and pyridine to a reaction flask, stirring the mixture, and performing a reaction at 40-100° C. for 2-12 hours to obtain dihydropyridine; S2. adding a trifluoromethylthio reagent, a difluoromethylthio reagent, or a trifluoromethyl reagent to the reaction flask, stirring the mixture, and performing a reaction at room temperature to 80° C. for 2-12 hours to obtain trifluoromethylthio-, difluoromethylthio- or trifluoromethyl-substituted dihydropyridine; and S3.

Abstract: The present invention relates to a reagent for exploiting natural gas hydrates, which includes a regent A and a regent B. The reagent A is PEG400-polyurethane prepolymer; the reagent B includes PEG400 and an initiator; and a volume ratio of the PEG400-polyurethane prepolymer, the PEG400 and the initiator is (1-3000):(1-1000):(1-2000). The reagent of the present invention has excellent performance and high stability, and can effectively “replace” the “water” of the natural gas hydrate; and moreover, the reaction is exothermic reaction to effectively increase the reaction rate, which reduces the energy loss on the one hand, and reduces the blockage of a gas passage caused by the secondary generation of the natural gas hydrates in a low-temperature high-pressure pipeline during transferring on the other hand.

Abstract: A novel composite biological agent based on a porous frame material, comprising porous frame materials and biomolecules. The porous frame materials cover a biological product, wherein the porous frame materials are metal-organic frame material (MOFs), covalent organic frame materials (COFs), and hydrogen-bonding organic frame materials (HOFs), and the biomolecules are any one or a combination of antibodies, enzymes, peptides, vaccines, nucleotides, and virus species. The composite biological agent uses the porous frame materials and biomolecules to form a porous frame material/biomolecule complex, and the biomolecules are coated to achieve the protection effect. Under the premise of remaining biomolecule activity, the system can achieve efficient separation and recovery of the porous materials and the biomolecules, so that the technical problems of synthesis, storage, release, etc. are solved, a good technical effect is achieved, and the biomolecules are effectively protected.

Abstract: A 5A5B6C tricyclic spironolactone derivative is provided with a formula XI: The present invention also relates to its preparation method and its applications in the areas of insecticide, nematicide, fungicide and anti-viral agent. The 5A5B6C tricyclic spironolactone derivatives in the present invention are high-performance, broad-spectrum, low-toxicity and low-ecological risk compounds with a wide range of applications in the areas of agriculture, horticulture, forestry and health.

Abstract: A peptide-crosslinked protein-imprinted polymer, preparation method, and application thereof. One method comprises: 1) dissolving a main monomer, functional monomers, a peptide crosslinking agent, and a template protein in an aqueous solution to obtain a mixed solution; 2) adding an initiator or initiator system to the mixed solution to initiate the polymerization when the peptide crosslinking agent exists in a helix conformation to obtain a polymer; 3) eluting the template protein when the peptide chain exists in a coil conformation to obtain a peptide-crosslinked protein-imprinted polymer. The peptide crosslinking agent is a peptide with a polymerizable double bond at its both ends, and being capable of undergoing helix-coil transition. The polypeptide crosslinking agent is a polypeptide having an amino acid sequence which has a polymerizable double bond at its both ends, being capable of undergoing a helix-coil conformational transformation.

Abstract: A chiral stationary phase comprises a porous framework material and biomolecules. The porous framework material includes one of the metal-organic framework (MOF) material, the covalent organic framework (COF) material and the hydrogen-bonded organic framework (HOF) material. The biomolecules are biological chiral resolving agents. A pore size of the porous framework material is 0.2-15 nm. The porous framework material serves as a solid carrier. The biomolecules are loaded into the porous framework material. The porous framework material is modified with one or more of carboxyl, hydroxyl, amino, aldehyde, double bonds and mercapto groups.

Abstract: The present disclosure relates to the technical field of terahertz (THz) wave measurement and relates to a photo-thermo-acoustic mechanism-based power measurement apparatus and measurement method for a terahertz wave at room temperature. The apparatus includes a terahertz wave power modulation component, a photo-thermo-acoustic conversion device, and an acoustic wave measurement component. In the present disclosure, the THz absorbing substance having a photo-thermo-acoustic effect is used as the photo-thermo-acoustic conversion device. A power-modulated terahertz wave is converted into an acoustic wave pulse by means of the photo-thermo-acoustic mechanism. The acoustic wave measurement component measures the acoustic wave pulse. A peak-to-peak value of a pulse of the measured acoustic wave is proportional to the power of the terahertz wave, thereby implementing the fast broadband measurement of the terahertz wave power at room temperature.

Abstract: A method for determining an optical constant of a material includes: acquiring ellipsometric parameters; obtaining a optical constant of the material corresponding to the ellipsometric parameters by a machine learning model; the machine learning model including a mapping relationship between the ellipsometric parameters and the material optical constant of the material corresponding to the ellipsometric parameters. The method uses the machine learning model to implement an automatic fitting of ellipsometric parameters. In the method, the optical constant of the material is calculated by a machine learning model, which no longer depends on the experiences of the experimenters, thereby reducing requirements for the operator, accelerating the fitting of the data curve when calculating the optical constants of the material and improving the operation efficiency.

Abstract: The present disclosure provides a metalens array and a spatial positioning method based on the metalens array. The metalens array includes at least two metalenses, each of the metalenses comprises a plurality of prism cells, each of the prism cells comprises a silicon dioxide substrate and a titanium oxide prism placed on the silicon dioxide substrate, and the plurality of prism cells are arranged periodically.

Abstract: A method for improving a bio-coupling efficiency between a protein and a nucleic acid based on an ?-helix handle includes the following steps. First, the handle carrying the non-natural amino acid (H-tag) is designed. Then, a recombinant expression plasmid encoding a fusion protein containing the H-tag and the protein to be tested is constructed. Subsequently, the fusion recombinant protein containing the non-natural amino acid in the H-tag is expressed and purified. Finally, the non-natural amino acid in the H-tag-fused protein and the coupling group on the nucleic acid substrate are efficiently connected by click chemistry. Thea-helix handle is used to provide a controllable reaction condition on the protein surface for the non-natural amino acid, avoiding the complex structure, charge and polar nanoenvironment around the surface of the protein to be tested.

Abstract: Provided are a cyclic peptide compound simulating a natural product structure- and a method for preparation thereof. The method is: the compound of formula I, a divalent palladium catalyst, and a silver salt undergoing an intramolecular arylation in a solvent under heating and stirring to construct a cyclic peptide, to generate the compound of formula II, in which the arylation sites are diverse, and can be extended to the side chain ?-position methyl or methylene of the majority hydrophobic amino acids to perform intramolecular arylation, thus overcoming the previous defect of the restriction of the types of selectable amino acids, and effectively constructing a novel aromatic ring-supported cyclic peptide compound. The aromatic ring support structure can form a novel 3D structure similar to a natural product, and provide a very favorable support for the subsequent construction of a cyclic peptide molecular library and high-throughput drug screening.

Abstract: A process method for producing a pesticide by using carbon dioxide includes: weighing a 1,3-cyclohexanedione substrate 1(a-e), a catalyst and Cs2CO3 in a Schlenk bottle, degassing, and continuously introducing 1 atm of carbon dioxide; adding a solvent and reacting for 48 h in an oil bath at 50° C. After the reaction was completed, post-treatment was carried out to obtain a 2-carboxyl-1,3-cyclohexanedione compound 2(a-e). The obtained acid is acylated and then added dropwise to a dichloromethane solution containing aniline to react for 2 h at room temperature. After the reaction, column chromatography was performed to obtain a pesticide compound 3(a-e). Adding the pesticide compound 3(a-e) into 50% concentrated sulfuric acid and refluxing at 80° C. for 8 hours. Through separation, a pesticide product compound 4(a-e) was obtained. The process method is simple, with low requirements on equipment, wide sources of raw materials, low cost, low toxicity and easy industrial scale-up production.

Abstract: A system for determining a second-order nonlinear susceptibility of a material includes a laser light source, a polarization modulator, a light collector, a polarization detector and a controller. The controller can obtain the second-order nonlinear susceptibility of the sample to be tested according to the test data. The system for determining the second-order nonlinear susceptibility of a material can directly test a material (block or film) with a thickness of hundreds of nanometers, and draw a second-order nonlinear susceptibility fitting curve of the material according to the test results of the optical system.

Abstract: A highly-dispersed hydrogenation catalyst, a preparation method thereof, and use thereof in the preparation of biofuel from palm oil or other oil are provided. The combination of maleic anhydride-grafted polypropylene (MA-PP) and a silane coupling agent (SCA) is introduced into an aluminum oxide composite carrier through organic amidation to obtain a uniformly-dispersed composite carrier with regular pores. Moreover, through a multi-stage impregnation and roasting process, a particle size of an active component is greatly reduced, and the dispersion of the active component and the number of active sites are improved. A hydrogenation catalyst with high hydrothermal stability, high hydrogenation activity, and long life is prepared based on the composite carrier with regular pores and used in the preparation of biofuel from vegetable oil or other oil through hydrodeoxygenation (HDO), which has great industrial application value.

Abstract: The invention relates to the complex of synthetic polymer and natural extracellular matrix for vascular grafts and their preparation methods. The components of biodegradable synthetic polymer in the preparation process can be chosen with different material proportions. The scaffolds with different fiber diameters, different fiber arrangements, different pore sizes and different pore structures can be prepared by electro-spinning, wet-spinning, melt-spinning, 3D printing, pouring, phase separation, particle leaching and other technologies. Among them, the natural extracellular matrix components come from a wide range of sources such as vascular tissues from different kinds of animals including arteries and veins of pigs and cattle or vascular tissues from human donors including umbilical cord vessels, etc. And its composition and content can be flexibly adjusted according to the demand.