Abstract: A cellulose-based all-solid-state polymer electrolyte separator, a preparation method thereof and an application thereof are provided. The cellulose separator is used as a skeleton, and solid-state polymer electrolyte is injected into pores of the separator using atomic layer deposition and dipping-coating processes. In addition, the polymer electrolyte remains in an amorphous structure at high temperatures by using an instantaneous quenching method, and ionic conductivity of the solid-state polymer electrolyte at room temperature is improved. After a surface of the solid-state polymer electrolyte separator is further coated with an alumina nanolayer, an electrochemical window width of the separator is significantly increased, and the solid-state polymer electrolyte separator is prevented from decomposing under a high voltage.

Abstract: Disclosed herein is a modified ribonucleotide comprising a nucleoside comprising 2?-O-acetylated ribose, and polyribonucleotides comprising the same. Also provided herein are compositions comprising a polyribonucleotide of the present disclosure and methods of making and using the same.

Abstract: An embodiment is directed to a solid state electrolyte-comprising Li or Li-ion battery cell, comprising an anode electrode, a cathode electrode with an areal capacity loading that exceeds around 3.5 mAh/cm2, an ionically conductive separator layer that electrically separates the anode and cathode electrodes, and one or more solid electrolytes ionically coupling the anode and the cathode, wherein at least one of the one or more solid electrolytes or at least one solid electrolyte precursor of the one or more solid electrolytes is infiltrated into the solid state Li or Li-ion battery cell as a liquid.

Abstract: In an embodiment, a Li-ion battery cell comprises an anode electrode with an electrode coating that (1) comprises Si-comprising active material particles, (2) exhibits an areal capacity loading in the range of about 3 mAh/cm2 to about 12 mAh/cm2, (3) exhibits a volumetric capacity in the range from about 600 mAh/cc to about 1800 mAh/cc in a charged state of the cell, (4) comprises conductive additive material particles, and (5) comprises a polymer binder that is configured to bind the Si-comprising active material particles and the conductive additive material particles together to stabilize the anode electrode against volume expansion during the one or more charge-discharge cycles of the battery cell while maintaining the electrical connection between the metal current collector and the Si-comprising active material particles.

Abstract: Battery electrode compositions are provided comprising core-shell composites. Each of the composites may comprise, for example, an active material, a collapsible core, and a shell. The active material may be provided to store and release metal ions during battery operation, whereby the storing and releasing of the metal ions causes a substantial change in volume of the active material. The collapsible core may be disposed in combination with the active material to accommodate the changes in volume. The shell may at least partially encase the active material and the core, the shell being formed from a material that is substantially permeable to the metal ions stored and released by the active material.

Abstract: Compositions and methods for synthesizing an RNA product are provided herein. For example, the present disclosure provides a method of producing an RNA product comprising incubating an in vitro transcription mixture, thereby producing an RNA product that comprises a plurality of single-stranded RNA molecules. In some embodiments, an in vitro transcription mixture comprises a DNA template comprising an RNA polymerase promoter sequence operatively linked to a target sequence; at least one RNA polymerase that recognizes the RNA polymerase promoter sequence; a plurality of ribonucleotides comprising at least two different types of ribonucleotides, each type comprising a different nucleoside; and a transcription buffer comprising an osmolyte.

Abstract: Disclosed herein is a modified ribonucleotide comprising a nucleoside comprising N4-acetylcytidine and/or 5-hydroxymethyluridine, and polyribonucleotides comprising the same. Also provided herein are compositions comprising a polyribonucleotide of the present disclosure and methods of making and using the same.

Abstract: Disclosed herein is a modified ribonucleotide comprising a nucleoside comprising N4-acetylcytidine and/or 5-hydroxymethyluridine, and polyribonucleotides comprising the same. Also provided herein are compositions comprising a polyribonucleotide of the present disclosure and methods of making and using the same.

Abstract: The present disclosure provides technologies for MYC inhibition, including, e.g. MYC fusion polypeptides and compositions comprising the same as well as methods of using the same. In particular, the present disclosure, among others, provides fusion polypeptides comprising a mutant MYC polypeptide and a repressor domain. In some embodiments, such fusion polypeptides and compositions comprising the same can be useful for inducing cancer cell apoptosis. Accordingly, in some embodiments, such fusion polypeptides and compositions comprising the same can be useful for cancer treatment.

Abstract: Unpurified or low pure soy phosphatidylserine is used to make cochleates. The cochleates contain about 40-74% soy phosphatidylserine, a multivalent cation and a biological active. A preferred cochleate contains the antifungal agent amphotericin B.

Abstract: Aspects relate to method of zinc-comprising nanowire fabrication, the method comprising forming a starting material comprising zinc metal or zinc metal alloy and at least one reactive metal, and exposing the starting material to one or more alcohols to obtain a reaction product comprising zinc-comprising nanowires, wherein the at least one reactive metal is more reactive than zinc to the one or more alcohols.

Abstract: Disclosed herein are fusion polypeptides comprising: (i) a fragment antigen comprising an epitope of a target protein antigen; and (ii) a complement binding polypeptide. The disclosure also provides fusion polynucleotides (e.g., mRNA) encoding the same. Also disclosed herein are methods of making and using the fusion polypeptides and fusion polynucleotides of the present disclosure.

Abstract: Metal-ion battery cells are provided that take advantage of the disclosed “doping” process. The cells may be fabricated from anode and cathode electrodes, a separator, and an electrolyte. A metal-ion additive may be incorporated into (i) one or more of the electrodes, (ii) the separator, or (iii) the electrolyte. The metal-ion additive provides additional donor ions corresponding to the metal ions stored and released by anode and cathode active material particles. An activation potential may then be applied to the anode and cathode electrodes to release the additional donor ions into the battery cell.

Abstract: Generally described herein are adhesion promoter compositions, which can be formed, for example, via a two-step synthetic process. In some embodiments, the first step of the synthetic process involves the hydrolysis and polycondensation of an organosilane monomer compound, thereby providing a polyorganosilane intermediate compound. In certain aspects, the organosilane compound may be hydrolyzed and polycondensed in the presence of a chain extender (e.g., a co-monomer) to provide an oligomeric adhesion promoter with greater degrees of functionalization. In some embodiments, the second step of the synthetic process involves the hydrosilylation of the polyorganosilane intermediate compound with a hydro silane-containing compound, resulting in a compound of the adhesion promoter.

Abstract: Disclosed herein is a modified ribonucleotide comprising a nucleoside comprising N4-acetylcytidine and/or 5-hydroxymethyluridine, and polyribonucleotides comprising the same. Also provided herein are compositions comprising a polyribonucleotide of the present disclosure and methods of making and using the same.

Abstract: This invention relates to polymer-based partially-open, hollow reservoirs in the nano-size to micro-size range that encapsulate an additive, which can be released from the reservoirs using specific event stimuli such as reduction-oxidation and voltage change, or at will, using the same stimuli. This invention also relates to method preparing such reservoirs, and for releasing the additive. This invention further relates to matrix that comprises such reservoirs and the method of preparing such matrix. This invention also relates to applications, for example in corrosion inhibition, lubrication, and adhesion, that benefit from using such a controlled release of an additive.

Abstract: An embodiment is directed to a solid state electrolyte-comprising Li or Li-ion battery cell, comprising an anode electrode, a cathode electrode with an areal capacity loading that exceeds around 3.5 mAh/cm2, an ionically conductive separator layer that electrically separates the anode and cathode electrodes, and one or more solid electrolytes ionically coupling the anode and the cathode, wherein at least one of the one or more solid electrolytes or at least one solid electrolyte precursor of the one or more solid electrolytes is infiltrated into the solid state Li or Li-ion battery cell as a liquid.

Abstract: A Li or Li-ion or Na or Na-ion battery cell is provided that comprises anode and cathode electrodes, a separator, and a solid electrolyte. The separator electrically separates the anode and the cathode. The solid electrolyte ionically couples the anode and the cathode. The solid electrolyte also comprises a melt-infiltration solid electrolyte composition that is disposed at least partially in at least one of the electrodes or in the separator.

Abstract: Linear covalently closed vectors, and compositions and methods for making same.

Abstract: According to some embodiments, an anti-microbial composition (e.g., an anti-microbial coating), and related methods, are generally described. The anti-microbial composition may be used to kill, inhibit growth, mitigate, and/or inhibit retention of one or more microbes and/or bacteria. The anti-microbial properties of the composition may be provided by a microbial inhibition material, which comprises a silane compound (e.g., a first silane compound) functionalized with a metal ion. The composition may also include a fingerprint inhibition material, which comprises a silane compound (e.g., a second silane compound) that may preferably be hydrophobic. The fingerprint inhibition material may comprise an invisible fingerprint material and/or an anti-fingerprint material. The invisible fingerprint material is configured to hide fingerprints by making them optically less visible (e.g., to the human eye), while the anti-fingerprint material may be configured to suppress the retaining of fingerprints.