Patents Assigned to National Cheng-Kung University
  • Publication number: 20250142917
    Abstract: A composite structure includes a dielectric layer, a two-dimensional graphene layer and a carbon quantum dot film. The dielectric layer is disposed on a first surface of a silicon substrate. The two-dimensional graphene layer is disposed on the dielectric layer. The carbon quantum dot film is disposed on the two-dimensional graphene layer.
    Type: Application
    Filed: December 14, 2023
    Publication date: May 1, 2025
    Applicant: National Cheng Kung University
    Inventors: Chia-Yun CHEN, Zhe-Hao LIU, Kuan-Han LIN, Jheng-Yi LI
  • Patent number: 12287292
    Abstract: A method for detecting an analyte comprises the following steps: providing a SERS-active substrate and a Raman spectra database; applying a sample onto the SERS-active substrate; applying an incident light by a Raman spectrometer onto the SERS-active substrate to generate a Raman spectrum of the sample; and comparing the Raman spectrum of the sample with a Raman spectra database to identify an analyte in the sample. The SERS-active substrate comprises: a support; a first dielectric layer disposed on the support, wherein the first dielectric layer is formed by a plurality of first nanofibers; and a plurality of noble metal particles formed on the plurality of first nanofibers.
    Type: Grant
    Filed: June 8, 2023
    Date of Patent: April 29, 2025
    Assignee: National Cheng Kung University
    Inventors: Jiunn-Der Liao, Han Lee, Kuan-Hung Liu
  • Publication number: 20250101965
    Abstract: A pulsed-plasma thruster using an unbalanced theta-pinch includes a gas-puff generator, an ionization convergent-divergent nozzle, and an accelerating coil set. The gas-puff generator supplies a gas puff in a pulsed manner; and the accelerating coil set is arranged on a side of a throat of the ionization convergent-divergent nozzle. After the gas puff enters the ionization convergent-divergent nozzle, an electric arc is generated between the pair of electrodes of the ionization convergent-divergent nozzle so that the gas puff is ionized and forms a plasma plume, and the electrodes are utilized to drive the accelerating coil set to generate axially non-uniform magnetic fields, to accelerate the plasma plume. Based on this, the control of thrust force generation is simple and reliable, with high energy utilization efficiency.
    Type: Application
    Filed: January 4, 2024
    Publication date: March 27, 2025
    Applicant: National Cheng Kung University
    Inventors: Po-Yu CHANG, Te-Yueh CHEN
  • Publication number: 20250092908
    Abstract: A single-layered hollow transmission shaft comprises a hollow shaft body. The hollow shaft body has a power-inputting end and a power-outputting end, which are formed at two opposite ends of the hollow shaft body, and at least one multi-start helix set. The multi-start helix set has a left-coiling multi-start helix section and a right-coiling multi-start helix section, which are arranged axially and have an equal pitch, number of circles, number of starts of helix and width of helix. By a single-layered structure and a structural design of the multi-start helix set, the single-layered hollow transmission shaft provides sufficient space for wiring of communication and can transmit power with pure torque while the shaft rotates, therefore increasing precision of torque detection, and can detect torque while rotating at high speed without installing any other external element and without affecting size of the space inside the shaft.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 20, 2025
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventor: Chao-Chieh LAN
  • Publication number: 20250090842
    Abstract: A method and system device to generate and deliver an electric field to a target a peripheral nerve with customized electric fields according to the nerve of interest, which may be superficial or deep in the human body, to elicits action potentials of the target nerve. The system utilizes a stimulator circuit which receives parameters of a stimulation protocol from an external control device, and assembles basic building waveforms, counters, and timers which when combined are directed to a current/voltage driver hardware (CDC) that generates the stimulation protocol.
    Type: Application
    Filed: November 23, 2024
    Publication date: March 20, 2025
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Wentai Liu, Meng-Ru Shen, Jung-Shun Lee, Chia-En Wong, Li-Hsien Chen, Ya-Ting Hsu
  • Publication number: 20250066943
    Abstract: The present invention provides a metal-nanoparticle-free surface-enhanced Raman scattering substrate, which comprises: an anodic aluminum oxide substrate with three-dimensional cavities, and a metal nano-film on the anodic aluminum oxide substrate. The surface-enhanced Raman scattering substrate of the present invention does not need to use metal nanoparticles, but instead uses a structure of metal nanofilm to generate a surface plasmonic resonance. Therefore, compared with the traditional surface-enhanced Raman scattering substrate with an addition of metal nanoparticles, the surface-enhanced Raman scattering substrate of the present invention has better uniformity, stability and reproducibility. The present invention utilizes an anodic aluminum oxide substrate with three-dimensional cavities, so that the surface-enhanced Raman scattering substrate has high sensitivity, high stability, and high reproducibility.
    Type: Application
    Filed: November 1, 2023
    Publication date: February 27, 2025
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Chen-Kuei CHUNG, Chung-Yu YU, Chin-An KU
  • Publication number: 20250067677
    Abstract: The present invention provides a food detection system including: an extraction equipment, a liquid to be identified, a laser light source, a Raman spectrometer, and a metal-nanoparticle-free surface-enhanced Raman scattering substrate. Without an addition of metal nanoparticles, the surface-enhanced Raman scattering substrate of the present invention has better stability and reproducibility compared to those traditional surface-enhanced Raman scattering substrate with metal nano particles. The present invention utilizes an anodic aluminum oxide substrate with two-dimensional and three-dimensional cavities, so that the surface-enhanced Raman scattering substrate has high sensitivity, high stability, and high reproducibility, and may therefore shorten the detection time and production cost of food detection. The invention also provides a food detection method using the food detection system, which is cheap, fast, stable and reliable.
    Type: Application
    Filed: November 1, 2023
    Publication date: February 27, 2025
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Chen-Kuei CHUNG, Chung-Yu YU, Ding-Yan LIN
  • Publication number: 20250062757
    Abstract: A multiple-reference-embedded comparator (MREC) circuit includes a tail current source circuit; an input transistor pair, coupled to the tail current source circuit, configured to receive differential input voltages and perform a first pre-amplification to generate first differential amplified voltages according to the differential input voltages; and a plurality of embedded reference (ER) branches, each coupled to the input transistor pair, each configured to perform a second pre-amplification to generate second differential amplified voltages according to the first differential amplified voltages, and to perform a discrete-time comparison to generate differential output voltages according to the second differential amplified voltages.
    Type: Application
    Filed: August 16, 2023
    Publication date: February 20, 2025
    Applicant: National Cheng Kung University
    Inventors: Jia-Ching Wang, Tai-Haur Kuo
  • Publication number: 20250061069
    Abstract: An accelerator system includes an off-chip memory, a bus, and an accelerator. The off-chip memory includes a first buffer. The accelerator includes a second buffer, a third buffer, a fourth buffer, an instruction fetching module, a load module, a storage module, a convolution control module, and a computation module. The instruction fetching module fetches instructions from the off-chip memory via the bus. The load module loads input data from the off-chip memory via the bus. The storage module stores the output data to the off-chip memory via the bus. The computation module performs convolution computations based on the input map and multiple kernels allocated by the convolution module. In response to loading the input data or instruction from the off-chip memory, the requested input data or instruction is transferred from the off-chip memory and temporarily stored in the first buffer.
    Type: Application
    Filed: November 15, 2023
    Publication date: February 20, 2025
    Applicant: National Cheng Kung University
    Inventors: Chung-ho CHEN, Cheng-you XIE
  • Patent number: 12228921
    Abstract: Embodiments of the present invention provide a multiple-variable predictive maintenance method for a component of a production tool and a computer program product thereof, in which a multiple-variable time series prediction (TSPMVA) and an information criterion algorithm are adapted to build a best vector autoregression model (VAR), thereby forecasting the complicated future trend of accidental shutdown of the component of the production tool. Therefore, the multiple-variable prediction of the present invention can improve the accuracy of prediction compared with the single-variable prediction.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: February 18, 2025
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Chin-Yi Lin, Yu-Ming Hsieh, Fan-Tien Cheng, Hsien-Cheng Huang
  • Patent number: 12224008
    Abstract: A non-volatile static random access memory includes: a static random access memory, a reading element and a first embedded non-volatile memory. The static random access memory includes a first inverter, a second inverter and two transistors, an output terminal of the first inverter and the input terminal of the second inverter are electrically connected to each other to serve as a Q node, an input terminal of the first inverter and an output terminal of the second inverter are electrically connected to each other to serve as a QB node, and the two transistors are electrically connected to the Q node and the QB node, respectively. The reading element is electrically connected to the Q node. The first embedded non-volatile memory is electrically connected to the QB node.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: February 11, 2025
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Darsen Duane Lu, Mohammed Aftab Baig, Siao-Shan Huang, Fu Yuan Chang
  • Publication number: 20250035666
    Abstract: A shear mode piezoelectric accelerometer includes a ring-shaped piezoelectric element, a central shaft, a mass block, a first electrode, and a second electrode. The ring-shaped piezoelectric element includes an outer ring wall and an inner ring wall. The central shaft is made of conductive material and is fixed through the inner ring wall of the ring-shaped piezoelectric element. The mass block is made of conductive material and includes a fixed element and a weight element. The fixed element has a fixed hole and is fixed to the outer ring wall of the ring-shaped piezoelectric element by fitting the fixed hole. The weight element is located on the fixed element on the opposite side away from the fixed hole. The first electrode is electrically connected to the central shaft. The second electrode is electrically connected to the mass block.
    Type: Application
    Filed: August 29, 2023
    Publication date: January 30, 2025
    Applicant: National Cheng Kung University
    Inventors: Cheng-Ying LI, Sheng-Yuan CHU
  • Patent number: 12207962
    Abstract: The present invention relates to a method for measuring muscle mass, including: a first selection step, wherein a frame selection information is obtained by using a frame to select a fascia region from a provided computed tomography image under the condition that the window width ranges from 300 HU to 500 HU and the window level ranges from 40 HU to 50 HU, wherein the selected range of the fascia region includes a muscle; and a second selection step, wherein a muscle information of the muscle is obtained by calculating a pixel value in the frame-selected fascia region under the condition that the HU value of the CT image ranges from ?29 HU to 150 HU.
    Type: Grant
    Filed: April 20, 2022
    Date of Patent: January 28, 2025
    Assignee: National Cheng Kung University
    Inventors: Yi-Shan Tsai, Yu-Hsuan Lai, Bow Wang, Cheng-Shih Lai, Chao-Yun Chen, Meng-Jhen Wu, Po-Tsun Kuo, Tsung-Han Lee
  • Patent number: 12211212
    Abstract: An image segmentation method includes the following steps: obtaining a target image; inputting the target image into a machine learning model to obtain an image segmentation parameter value corresponding to the target image; executing an image segmentation algorithm on the target image according to the image segmentation parameter value to obtain an image segmentation result, wherein the image segmentation result is segmenting the target image into object regions; and displaying the image segmentation result. In addition, an electronic device and storage medium using the method are also provided.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: January 28, 2025
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Yi-Shan Tsai, Cheng-Shih Lai, Chao-Yun Chen, Meng-Jhen Wu, Yun-Chiao Wu, Hsin-Yi Feng, Po-Tsun Kuo, Kai-Yi Wang, Wei-Cheng Su
  • Publication number: 20250025512
    Abstract: Disclosed herein is an isolated population of cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSCs), wherein the isolated population of cardiomyocytes comprises genomic deletions in HCN1 and HCN4 genes. According to some embodiments of the present disclosure, the isolated population of cardiomyocytes further comprises genomic deletions in HCN2 and HCN3 genes. Also disclosed herein are methods of producing the isolated population of cardiomyocytes, and methods of treating subjects suffering from cardiac diseases by administering the isolated population of cardiomyocytes to the subjects.
    Type: Application
    Filed: July 18, 2023
    Publication date: January 23, 2025
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Yen-Wen LIU, Yan-Shen SHAN
  • Patent number: 12202825
    Abstract: Pyrimidine compounds of formula (I) shown herein. Also disclosed are pharmaceutical compositions containing one of the pyrimidine compounds and methods of using the pyrimidine compounds to treat or prevent chemotherapy-induced peripheral neuropathy.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: January 21, 2025
    Assignees: National Health Research Institutes, National Cheng Kung University
    Inventors: Jang-Yang Chang, Meng-Ru Shen, Kak-Shan Shia, Chien-Huang Wu
  • Publication number: 20250023439
    Abstract: An offset overlap type of a modulated ferromagnetic pole piece ring and a manufacturing method thereof are provided. The modulated ferromagnetic pole piece ring comprises a plurality of ring pieces overlapped with each other. At least one ring piece comprises a plurality of main ribs, a plurality of inner ribs, and a plurality of outer ribs. The main ribs are arranged in a circular manner with intervals in between, and a plurality of first gaps and a plurality of second gaps are formed alternately between the main ribs, wherein the inner ribs are respectively located in the first gaps, and the outer ribs are respectively located in the second gaps.
    Type: Application
    Filed: April 10, 2024
    Publication date: January 16, 2025
    Applicant: National Cheng Kung University
    Inventors: Mi-ching TSAI, Po-wei HUANG, Wen-hao YANG, Tsung-wei CHANG
  • Patent number: 12196550
    Abstract: An optical measurement system measuring optical parameters of an object is provided. The object includes at least two light-transmitting layers. The optical measurement system includes a light source module, an image capture module, and a controller. The light source module emits at least two measurement light beams toward the object. The measurement light beams are respectively incident on the object at different angles. The image capture module receives light spots formed on a sensing surface of the image capture module by at least two first light beams after the measurement light beams are reflected by the object and at least two second light beams after the measurement light beams are refracted and reflected between the object. The controller is electrically connected to the image capture module to obtain positions of the light spots. The controller calculates the optical parameters of the object according to the positions of the light spots.
    Type: Grant
    Filed: August 24, 2022
    Date of Patent: January 14, 2025
    Assignee: National Cheng-Kung University
    Inventors: Chien-Sheng Liu, Wen-Yu Shih
  • Publication number: 20250012645
    Abstract: A multi-dimensional strain sensing device includes a flexible substrate, two piezoelectric semiconducting films, a first pair of electrodes and a second pair of electrodes. The two piezoelectric semiconducting films are formed on opposite sides of the flexible substrate respectively. The first pair of electrodes are formed on one of the two piezoelectric semiconducting films and opposite to the flexible substrate. The second pair of electrodes are formed on the other one of the two piezoelectric semiconducting films and opposite to the flexible substrate. The present disclosure further proposes a method for sensing types of external motions by the multi-dimensional strain sensing device, a method for forming a ternary valued logic device by the multi-dimensional strain sensing device and a ternary valued logic system.
    Type: Application
    Filed: July 7, 2023
    Publication date: January 9, 2025
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Jit DUTTA, Chuan Pu LIU
  • Patent number: 12190506
    Abstract: An interactive image marking method is introduced. The interactive image marking method includes the following steps, displaying a target image and at least one marked region in the target image; receiving an interactive signal, where the interactive signal corresponds to a first pixel of the target image; calculating a correlation between the first pixel and pixels of the target image, and determining a correlation range in the target image according to the correlation; editing the marked region according to the correlate range; and displaying the edited marked region. In addition, an electronic device and a recording medium using the method are also introduced.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: January 7, 2025
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Yi-Shan Tsai, Cheng-Shih Lai, Chao-Yun Chen, Meng-Jhen Wu, Yun-Chiao Wu, Hsin-Yi Feng, Po-Tsun Kuo, Kai-Yi Wang, Wei-Cheng Su