Patents Assigned to National Cheng-Kung University
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Patent number: 11435353Abstract: The present invention provides a method of evaluating drug resistance in hormone therapy including the following steps. Firstly, a primary level of TRBP in a subject is measured, and an effective amount of tamoxifen, an active form of tamoxifen or an analogous of tamoxifen is provided to the subject. Then, a level of TRBP in the subject is measured after providing tamoxifen, the active form of tamoxifen or the analogous of tamoxifen. Finally, a level change of TRBP in the subject is discriminated to determine a tamoxifen resistance.Type: GrantFiled: December 4, 2018Date of Patent: September 6, 2022Assignee: National Cheng Kung UniversityInventors: Pai-Sheng Chen, Jie-Ning Li, Yao-Lung Kuo, Ming-Yang Wang
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Patent number: 11434537Abstract: Provided is a method of accurate and sensitive characterization and prognosis of colorectal cancer in a subject. The method includes obtaining a cancer tissue from the subject and determining the expression level of a miRNA and a target gene of the miRNA. Also provided is a kit for prognosis of colorectal cancer in a subject in need thereof.Type: GrantFiled: February 14, 2020Date of Patent: September 6, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Nan-Haw Chow, Chien-An Chu, Hsiao-Sheng Liu, Chung-Ta Lee
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Publication number: 20220276097Abstract: An optical sensor circuit is provided. In the optical sensor circuit, an output stage circuit transmits a voltage of first and second node to the output line according to a first driving signal. A first sensor is configured to generate a first photocurrent according to a first color light that senses an ambient light, and generate a second photocurrent according to a second color light. A second sensor is configured to generate a third photocurrent according to a third color light, and generate a fourth photocurrent according to the second color light. In a sensing phase, when the first sensor senses the first color light, and the second sensor senses the third color light, the first sensor adjusts a voltage level of the voltage according to the first photocurrent, and the second sensor adjusts the voltage level of the voltage according to the third photocurrent.Type: ApplicationFiled: May 11, 2022Publication date: September 1, 2022Applicants: Au Optronics Corporation, National Cheng-Kung UniversityInventors: Chih-Lung Lin, Chia-En Wu, Chia-Lun Lee, Jui-Hung Chang, Jian-Shen Yu
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Publication number: 20220278129Abstract: A multi-gate ferroelectric memory comprises a fin-shaped channel layer, a front ferroelectric layer disposed on one side of the fin-shaped channel layer, a back ferroelectric layer disposed on another side of the fin-shaped channel layer, a front gate attached to the front ferroelectric layer and away from the fin-shaped channel layer, wherein the front gate is configured to connect a word line, and a back gate attached to the back ferroelectric layer and away from the fin-shaped channel layer, wherein the back gate is configured to connect a bit line. The present disclosure further discloses a memory array device, comprises a plurality of the multi-gate ferroelectric memories arranged as an array, a plurality of word lines and a plurality of bit lines.Type: ApplicationFiled: May 11, 2021Publication date: September 1, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Darsen Duane LU, Chi-Jen LIN
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Patent number: 11426793Abstract: A method is provided to fabricate a high-power module. A non-touching needle is used to paste a slurry on a heat-dissipation substrate. The slurry comprises nano-silver particles and micron silver particles. The ratio of the two silver particles is 9:1˜1:1. The slurry is pasted on the substrate to be heated up to a temperature kept holding. An integrated chip (IC) is put above the substrate to form a combined piece. A hot presser processes thermocompression to the combined piece to form a thermal-interface-material (TIM) layer with the IC and the substrate. After heat treatment, the TIM contains more than 99 percent of pure silver with only a small amount of organic matter. No volatile organic compounds would be generated after a long term of use. No intermetallic compounds would be generated while the stability under high temperature is obtained. Consequently, embrittlement owing to procedure temperature is dismissed.Type: GrantFiled: December 3, 2018Date of Patent: August 30, 2022Assignee: National Cheng Kung UniversityInventors: In-Gann Chen, Hung-Cheng Chen, Chia-Ming Yang, Steve Lien-Chung Hsu, Chang-Shu Kuo
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Publication number: 20220269752Abstract: An execution method for convolution computation is disclosed, which includes: dividing an input image of N channels into a first tile to an X-th tile according to a feature tile; sequentially performing convolution computations on the data in the first tile to the X-th tile of the input image of the N channels, and storing the computation results as output data; mapping the data in each of the tiles by a kernel, and performing multiply-accumulate operations on the mapped data in each of the tiles, wherein each time the multiply-accumulate operation performed on the data mapped by the kernel is complete, the kernel is shifted to change the mapped data in said tile, and multiply-accumulate operation is performed on the changed mapped data until the multiply-accumulate operations performed on all of the data in said tile are complete, thereby finishing the convolution computation of said tile.Type: ApplicationFiled: February 10, 2022Publication date: August 25, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Chung-ho Chen, Ting-jia WU, Cheng-chih HSIAO, Hsiang-yu WANG, Han-qun Huang
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Publication number: 20220262426Abstract: A memory system includes a plurality of first memory units, a plurality of read word lines, and a plurality of read bit lines. Each first memory unit of the plurality of first memory units includes a second memory unit, a first transistor coupled to the second memory unit, and a second transistor coupled to the second memory unit and the first transistor. Each read word line of the plurality of read word lines is coupled to a plurality of first transistors disposed along a corresponding row. Each read bit line of the plurality of read bit lines is coupled to a plurality of second transistors disposed along a corresponding column.Type: ApplicationFiled: June 18, 2021Publication date: August 18, 2022Applicant: National Cheng Kung UniversityInventors: Lih-Yih Chiou, Yu-Wei Lin, Wei-Shuo Ling
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Patent number: 11401232Abstract: Disclosed herein are modified chromium-dpoed zinc gallate (ZGC) nanocubes, which are characterized in respectively having a concave surface that is modified with (3-aminopropyl)triethoxysilane (APTES). The modified ZGC nanocubes produce long lasting luminescence (LLL) that lasts for at least 1.5 hours under X-ray or UV excitation. Also disclosed herein are methods for the preparation of the modified ZGC nanocubes; and methods for imaging an area of interest (e.g., cancer) in a live subject using the modified ZGC nanocubes as an imaging agent.Type: GrantFiled: June 19, 2020Date of Patent: August 2, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Chen-Sheng Yeh, Liu-Chun Wang, Zheng-Zhe Chen, Ping-Ching Wu, Chia-Hao Su
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Publication number: 20220220644Abstract: A warp scheduling method includes: storing plural of first warps issued to a streaming multiprocessor in an instruction buffer module; marking plural of second warps which are able to be scheduled in the first warps by a schedulable warp indication window, wherein the number of the marked second warps is the size of the schedulable warp indication window; sampling the read/storage unit stall cycle in each time interval to obtain a read/storage unit stall cycle proportion; comparing the read/storage unit stall cycle proportion with the stall cycle threshold, and adjusting the size of the schedulable warp indication window and determining the second warps according to the comparison result; issuing the second warps from the instruction buffer module to a corresponding one of the processing modules for execution.Type: ApplicationFiled: April 12, 2021Publication date: July 14, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Chung-ho CHEN, Chien-ming CHIU, Yu-hsiang WANG
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Patent number: 11383446Abstract: An additive manufacturing (AM) system, an AM method, and an AM feature extraction method are provided. The AM system includes an AM tool, a product metrology system, an in-situ metrology system, a virtual metrology (VM) system, a compensator, a track planner, a controller, a simulator and an augmented reality (AR) device. The simulator is used to find feasible parameter ranges, while the AR device is used to support operations and maintenance of the AM tool. The product metrology system, the in-situ metrology system and the VM system are integrated to estimate the variation of material on a powder bed of the AM tool. The compensator is used for compensating the process variation by adjusting process parameters. The product metrology system is used to measure the quality of products. The in-situ metrology system is used to collect features of melt pools on the powder bed.Type: GrantFiled: October 2, 2019Date of Patent: July 12, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Haw-Ching Yang, Yu-Lung Lo, Hung-Chang Hsiao, Shyh-Hau Wang, Min-Chun Hu, Chih-Hung Huang, Fan-Tien Cheng
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Patent number: 11383450Abstract: An additive manufacturing (AM) system, an AM method, and an AM feature extraction method are provided. The AM system includes an AM tool, a product metrology system, an in-situ metrology system, a virtual metrology (VM) system, a compensator, a track planner, a controller, a simulator and an augmented reality (AR) device. The simulator is used to find feasible parameter ranges, while the AR device is used to support operations and maintenance of the AM tool. The product metrology system, the in-situ metrology system and the VM system are integrated to estimate the variation of material on a powder bed of the AM tool. The compensator is used for compensating the process variation by adjusting process parameters. The product metrology system is used to measure the quality of products. The in-situ metrology system is used to collect features of melt pools on the powder bed.Type: GrantFiled: April 22, 2020Date of Patent: July 12, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Haw-Ching Yang, Yu-Lung Lo, Hung-Chang Hsiao, Shyh-Hau Wang, Min-Chun Hu, Chih-Hung Huang, Fan-Tien Cheng
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Patent number: 11388134Abstract: A wireless network-based voice communication security protection method, which enables VoWiFi (Voice over Wi-Fi) to verify and prevent potential risks in communication, and secures the environment of network communications that can be verified by a user device. A real-time user interface indicates security and quality of the current network call and provides advice on when to cancel a call. A telecommunications provider side interface checks if the user's network communication environment is safe, and provides real-time recommendations to the user regarding the security status of the call. The user device side self-check interface and the telecommunications provider side detection interface simultaneously detect whether or not the user's network communication environment is secure.Type: GrantFiled: May 28, 2020Date of Patent: July 12, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Jung-Shian Li, I-Hsien Liu, Keng-Hao Chang, Kuan-Chu Lu
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Predictive maintenance method for component of production tool and computer program product thererof
Patent number: 11378946Abstract: Embodiments of the present invention provide a predictive maintenance method for a component of a production tool, in which a time series prediction (TSP) algorithm and an information criterion algorithm are adapted to build a TSP model, thereby forecasting the complicated future trend of accidental shutdown of the component of the production tool. In addition, an alarm scheme is provided for performing maintenance immediately when the component is very likely to enter a dead state, and a death related indicator (DCI) is provided for quantitatively showing the possibility of the component entering the dead state.Type: GrantFiled: April 24, 2020Date of Patent: July 5, 2022Assignee: NATIONAL CHENG KUNG UNIVERSITYInventors: Chin-Yi Lin, Yu-Ming Hsieh, Fan-Tien Cheng, Hsien-Cheng Huang -
Patent number: 11379558Abstract: The present invention relates to computing-implemented method and system that improves matrix multiplication efficiency, especially to method and system optimizing matrix multiplication using sparse basis approach. Matrices to be multiplied are organized into specially ordered vectors with zero values, facilitates speed up during linear combination computation or synthesis process.Type: GrantFiled: May 12, 2020Date of Patent: July 5, 2022Assignee: National Cheng Kung UniversityInventors: Gwo Giun Lee, Shih-Yu Chen
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Publication number: 20220206768Abstract: A compiler includes a front-end module, an optimization module, and a back-end module. The front-end module pre-processes a source code to generate an intermediate code. The optimization module optimizes the intermediate code. The back-end module translates the optimized intermediate code to generate a machine code. Optimization includes translating a branch instruction in the intermediate code into performing the following operations: establishing a post dominator tree for the branch instruction to find an immediate post dominator of the branch instruction as a reconverge point of a first path and a second path of the branch instruction; inserting a specific instruction at the front end of the reconverge point, so as to jumping to execute the instructions of the second path on the condition that once the specific instruction on the first path is executed.Type: ApplicationFiled: March 29, 2021Publication date: June 30, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Chung-ho Chen, Dun-jie Chen, Feng-ming Hsu, Sheng-yao Lin
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Patent number: 11371885Abstract: An optical sensor circuit is provided. In the optical sensor circuit, an output stage circuit transmits a voltage of first and second node to the output line according to a first driving signal. A first sensor is configured to generate a first photocurrent according to a first color light that senses an ambient light, and generate a second photocurrent according to a second color light. A second sensor is configured to generate a third photocurrent according to a third color light, and generate a fourth photocurrent according to the second color light. In a sensing phase, when the first sensor senses the first color light, and the second sensor senses the third color light, the first sensor adjusts a voltage level of the voltage according to the first photocurrent, and the second sensor adjusts the voltage level of the voltage according to the third photocurrent.Type: GrantFiled: October 7, 2019Date of Patent: June 28, 2022Assignees: Au Optronics Corporation, National Cheng-Kung UniversityInventors: Chih-Lung Lin, Chia-En Wu, Chia-Lun Lee, Jui-Hung Chang, Jian-Shen Yu
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Patent number: 11374434Abstract: A radio frequency energy-harvesting apparatus is applied to a radio frequency energy-transmitting apparatus with a location detection function. The radio frequency energy-harvesting apparatus includes a direct current signal receiving-processing unit, a rectification and harmonic generation unit, and a radar wave receiving-transmitting unit. The rectification and harmonic generation unit is electrically connected to the direct current signal receiving-processing unit. The radar wave receiving-transmitting unit is electrically connected to the rectification and harmonic generation unit.Type: GrantFiled: October 25, 2019Date of Patent: June 28, 2022Assignees: DELTA ELECTRONICS, INC., NATIONAL CHENG KUNG UNIVERSITYInventors: Tzuen-Hsi Huang, Sheng-Fan Yang, Chun-Cheng Chen, Pei-Jung Chung, Chun-Yi Lu
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Publication number: 20220199999Abstract: A cathode material and a fabricating method thereof, and a lithium-ion battery are described. The cathode material is a 1D metal-organic coordination polymer of [CuL(Py)2]n, and its structure is formed by interlinking organic ligands (L) and metals (Cu). The cathode material can use redox active sites on both the metal and organic ligand to carry out multi-electron transfer. A N bond contained in L together with a benzene ring of L in an adjacent polymer chain form a weak interaction of C?N . . . ?. In addition, a Py of adjacent polymer chains also have an interaction of ? . . . ?. Therefore, [CuL(Py)2]n chains are closely interlaced and packed, but there is still enough regular space for lithium ions to enter and exit quickly, so it can be charged and discharged rapidly and exhibits high power density.Type: ApplicationFiled: April 18, 2021Publication date: June 23, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Teng-hao CHEN, Kaveevivitchai Watchareeya, An-che Li, Cheng-han Chang
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Publication number: 20220189334Abstract: A cognition evaluation method, comprises: obtaining brain physiology information associated with a subject by a brain state measuring instrument, obtaining a plurality of cognitive aspects according to the brain physiology information, selecting at least one of the cognitive aspects according to a sport type as at least one sport cognitive aspect, obtaining a cognition task outcome corresponding to the at least one sport cognitive aspect, and evaluating and outputting a sport cognition level of the at least one sport cognitive aspect according to the cognition task outcome. The present disclosure further provides a cognition evaluation system.Type: ApplicationFiled: February 3, 2021Publication date: June 16, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Fu-Zen SHAW, Sheng-Fu LIANG, Ren-Yi LIN
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METHOD OF TRAINING A SPEECH RECOGNITION MODEL OF AN EXTENDED LANGUAGE BY SPEECH IN A SOURCE LANGUAGE
Publication number: 20220189462Abstract: A method of training a speech recognition model of an extended language by speech in a source language includes the following steps: creating a phonetic reference table of the source language, wherein the phonetic reference table includes a source language audio file and a source language phonetic transcription corresponding to each other; obtaining an extended language text file of the extended language; marking the extended language text file with an extended language phonetic transcription to create a text reference table of the extended language; training an acoustic model of the extended language by the phonetic reference table and the text reference table; and training a language model of the extended language by the extended language text file of the extended language; wherein the speech recognition model of the extended language includes the acoustic model and the language model of the extended language.Type: ApplicationFiled: August 31, 2021Publication date: June 16, 2022Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: Wen-Hsiang LU, Shao-Chuan SHEN, Ching-Jui LIN