Patents Assigned to NATIONAL INSTITUTE
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Patent number: 10669159Abstract: Provided is a complex oxide that has a high hydrogen content, contains almost no impurity phase, and is suitable for proton conductivity. The complex oxide is represented by a chemical formula Li7-xHxLa3M2O12 (M represents Zr and/or Hf, and 3.2<x?7) and is a single phase of a garnet type structure belonging to a cubic system. A method for producing the complex oxide includes an exchange step of bringing a raw material complex oxide represented by a chemical formula Li7-xHxLa3M2O12 (M represents Zr and/or Hf, and 0?x?3.2) and a compound having a hydroxy group or a carboxyl group into contact with each other to exchange at least some of lithium of the raw material complex oxide and hydrogen of the compound having a hydroxy group or a carboxyl group.Type: GrantFiled: August 19, 2016Date of Patent: June 2, 2020Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Junji Akimoto, Naoki Hamao, Kunimitsu Kataoka
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Patent number: 10670610Abstract: Disclosed are specific biomarkers that allow for early testing of preeclampsia/HELLP syndrome. Thus, a method is provided predicting preeclampsia in a pregnant woman. Also disclosed is a kit comprising means for assaying a sample from a pregnant woman for the concentrations of the specific biomarkers.Type: GrantFiled: June 13, 2013Date of Patent: June 2, 2020Assignees: Wayne State University, The United States of America as represented by The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health, Semmelweis University, Genesis Theranostix Korlatolt Felelossegu TarsasagInventors: Adi L. Tarca, Nandor Than, Gabor Juhasz, Adrienna Katalin Kekesi, Hamutal Meiri, Zoltan Papp, Roberto Romero
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Publication number: 20200166497Abstract: An analysis apparatus (100) includes an image acquisition unit (110) and an analysis unit (120). The image acquisition unit (110) acquires image data of a microfossil in a sample collected from a stratum. The analysis unit (120) analyzes the image data acquired by the image acquisition unit (110) using a machine learning result to analyze a taxon or kind of the microfossil in the image data.Type: ApplicationFiled: May 10, 2018Publication date: May 28, 2020Applicants: NEC CORPORATION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Yousuke TAIRA, Naoki KUWAMORI, Tatsuhiko HOSHINO, Jonaotaro ONODERA, Tatsuhiko YAMAGUCHI, Kyoko TOMIOKO, Takuya ITAKI
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Publication number: 20200168460Abstract: A semiconductor substrate includes a single crystal Ga2O3-based substrate and a polycrystalline substrate that are bonded to each other. A thickness of the single crystal Ga2O3-based substrate is smaller than a thickness of the polycrystalline substrate, and a fracture toughness value of the polycrystalline substrate is higher than a fracture toughness value of the single crystal Ga2O3-based substrate.Type: ApplicationFiled: July 9, 2018Publication date: May 28, 2020Applicants: TAMURA CORPORATION, SICOXS Corporation, National Institute of Information and Communications TechnologyInventors: Akito KURAMATA, Shinya WATANABE, Kohei SASAKI, Kuniaki YAGI, Naoki HATTA, Masataka HIGASHIWAKI, Keita KONISHI
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Publication number: 20200166547Abstract: A resistance measuring device includes an amplifying unit including an amplifier, a first and a second current supply unit, a voltage detection unit, and a controller. The controller controls the voltage detection unit to detect a first output voltage of an output terminal of the amplifier in a state where the current of the first current source flows in a forward direction to a measurement target resistor by controlling the first current supply unit, controls the voltage detection unit to detect a second output voltage of the output terminal of the amplifier in a state where the current of the second current source flows in a reverse direction to the measurement target resistor by controlling the second current supply unit, and calculates a resistance value of the measurement target resistor based on the detected first output voltage and the detected second output voltage.Type: ApplicationFiled: November 4, 2019Publication date: May 28, 2020Applicant: Ulsan National Institute of Science and TechnologyInventors: Jae Joon KIM, Subin CHOI
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Patent number: 10663456Abstract: The present invention provides means for evaluating harmfulness of a chemical substance before occurrence of cell death, that is, more quickly and sensitively compared to conventional methods wherein the remaining viable cell count is determined using a reductive coloring reagent after a period of time required for occurrence of cell death due to the chemical substance. A double-stranded RNA probe comprising an RNA strand labeled with a fluorescent dye A that emits fluorescence, and an RNA strand labeled with a fluorescent dye B that quenches emission from a fluorescent dye in the vicinity thereof, wherein the fluorescence is quenched in a double-stranded state due to occurrence of fluorescence resonance energy transfer (FRET) between the two kinds of fluorescent dyes.Type: GrantFiled: July 6, 2016Date of Patent: May 26, 2020Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Hidenori Tani, Masaki Torimura, Hiroaki Sato
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Patent number: 10662374Abstract: Provided are a phosphor, a manufacture thereof, and an illuminating device and an image display device using same which has excellent blue excitation characteristics of at least 440 nm and not exceeding 449 nm. The phosphor of the present invention includes an inorganic compound in which an AlON crystal, an AlON solid solution crystal, or an inorganic crystal having a same crystal structure as AlON, includes at least Mn and an A element (where the A element is a monovalent metal element) and, if necessary, a D element (where the D element is an element other than Mn, the A element, Al, O, and N) wherein, upon irradiation of an excitation source, the phosphor emits fluorescence having a peak wavelength in a range of at least 490 nm and not exceeding 550 nm.Type: GrantFiled: May 13, 2016Date of Patent: May 26, 2020Assignee: National Institute for Materials ScienceInventor: Naoto Hirosaki
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Patent number: 10660890Abstract: An HDAC6-specific inhibitor (i.e., a compound of Formula I or II) is shown to reduce the pathogenesis associated with polycystic disease. Administration of an HDAC6-specific inhibitor attenuated many of the symptoms characteristic of polycystic liver disease including cyst formation, cyst growth and cholangiocyte proliferation. Treatment with a HDAC6-specific inhibitor also increased the amount of bile duct acetylated tubulin and ?-catenin phosphorylation and/or acetylation while reducing bile duct ?-catenin synthesis. These results demonstrate that HDAC6 is overexpressed in cystic cholangiocytes and that its pharmacological inhibition reduces cholangiocyte proliferation and cyst growth.Type: GrantFiled: October 24, 2014Date of Patent: May 26, 2020Assignee: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR)Inventors: Sergio A. Gradilone, Nicholas F. LaRusso
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Patent number: 10665776Abstract: Provided is a magnetoresistance effect element in which a tunnel barrier layer stably has a cation disordered spinel structure. This magnetoresistance effect element includes a first ferromagnetic layer, a second ferromagnetic layer, and a tunnel barrier layer disposed between the first ferromagnetic layer and the second ferromagnetic layer. In addition, the tunnel barrier layer is an oxide of MgxAl1-x (0?x<1) and an amount of oxygen in the tunnel barrier layer is lower than an amount of oxygen in a fully oxidized state in which the oxide has an ordered spinel structure.Type: GrantFiled: February 14, 2019Date of Patent: May 26, 2020Assignees: TDK CORPORATION, NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Shinto Ichikawa, Katsuyuki Nakada, Seiji Mitani, Hiroaki Sukegawa, Kazuhiro Hono, Tadakatsu Ohkubo
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Patent number: 10661267Abstract: Provided is an electric pipette system, including: an operating condition receiving milt configured to receive an operating condition of a manipulation operation to foe occur next; a suction/discharge operating unit configured to perform at least any one of a suction operation and a discharge operation of a liquid by an electric pipette based cm the operating condition; an information collecting unit configured to collect various types of information during the suction operation or the discharge operation of the liquid; and an information recording unit configured to record the information.Type: GrantFiled: March 2, 2017Date of Patent: May 26, 2020Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KABUSHIKI KAISHA YASKAWA DENKI, ROBOTIC BIOLOGY INSTITUTE INC.Inventors: Toru Natsume, Naoyuki Sasaki, Kenji Matsukuma, Makoto Umeno, Tatsuro Ipposhi
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Patent number: 10663385Abstract: A measurement apparatus for carrying out an indentation creep test on a specimen, including a measurement control apparatus that includes a load measurement device, a constant-load compression device configured to compress a tip of a transparent indenter to a surface of the specimen, and an image capturing device configured to optically capture an image including a contact area portion which is a part of the specimen to which the load is applied by the constant-load compression device. The apparatus also includes an information processing apparatus that includes an image analysis unit configured to analyze a contact area, and a physical property value calculation unit. The physical property value calculation unit conducts linear regression with respect to a plot of a logarithmic value of the contact stress and a logarithmic value of the contact strain rate so as to determine a creep index n and creep constant k.Type: GrantFiled: June 1, 2016Date of Patent: May 26, 2020Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventor: Tatsuya Miyajima
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Publication number: 20200158288Abstract: A method for dispensing liquefied fuel, the method including: providing a non-petroleum fuel as a liquefied fuel to a storage tank; increasing pressure of the liquefied fuel to a target pressure using a pump disposed within the storage tank, where a first portion of the liquefied fuel is bypassed around or at least partially around a heat exchanger, and a second portion of the liquefied fuel is discharged to the heat exchanger, where the heat exchanger is configured to warm the second portion of the liquefied fuel. A dispenser is provided that incorporates a control system that allows coordinated fueling of one or more vehicles simultaneously, where the heat exchanger uses only the fuel itself without external refrigeration to manage final dispensing temperature and the fueling station does not include a storage subsystem disposed between the pump and the dispenser.Type: ApplicationFiled: September 20, 2019Publication date: May 21, 2020Applicants: NATIONAL INSTITUTE OF CLEAN-AND-LOW-CARBON ENERGYInventors: Xianming Jimmy LI, Jeff PICKLES, Edward YOUN, Jeff ALLEN, Anthony KU, Cullen HALL
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Publication number: 20200156923Abstract: A fluid bypass method for controlling the temperature of a non-petroleum fuel, the fluid bypass method includes: providing a fuel at a pressure sufficient to effect a desired flow rate to a vehicle, the fuel being at a liquid or substantially supercritical thermodynamic state requiring further heat addition in a vaporizer; and diverting a bypass stream with partial or no vaporization to a heat exchanger as a cold fluid on a cold side of the heat exchanger. The method further includes providing a remainder stream of the fuel to the vaporizer; mixing the remainder stream outflowed from the vaporizer with the cold fluid outflowed from the cold side of the heat exchanger to form a combined fuel stream; and providing the combined fuel stream to the heat exchanger as a warm fluid on a warm side of the heat exchanger.Type: ApplicationFiled: August 6, 2019Publication date: May 21, 2020Applicants: CHINA ENERGY INVESTMENT CORPORATION LIMITED, NATIONAL INSTITUTE OF CLEAN-AND-LOW-CARBON ENERGYInventors: Xianming Jimmy LI, Edward YOUN, Jeff PICKLES, Surinder SINGH
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Publication number: 20200157571Abstract: The present invention enables simultaneous and stable expression of a plurality of foreign genes by using a stealthy RNA gene expression system that is a complex that does not activate the innate immune mechanism and is formed from an RNA-dependent RNA polymerase, a single-strand RNA binding protein, and negative-sense single-strand RNAs including the following (1) to (8): (1) a target RNA sequence that codes for any protein or functional RNA; (2) an RNA sequence forming a noncoding region and derived from mRNA expressed in animal cells; (3) a transcription initiation signal sequence recognized by the RNA-dependent RNA polymerase; (4) a transcription termination signal sequence recognized by the polymerase; (5) an RNA sequence containing a replication origin recognized by the polymerase; (6) an RNA sequence that codes for the polymerase and of which codons are optimized for the species from which an introduction target cell is derived; (7) an RNA sequence that codes for a protein for regulating the activity oType: ApplicationFiled: December 4, 2019Publication date: May 21, 2020Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, TOKIWA-BIO INC.Inventors: Mahito Nakanishi, Minoru Iijima
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Publication number: 20200157688Abstract: The present invention provides a surface treatment method that improves antimicrobial activity of copper or a copper alloy and enhances immediate effects of antimicrobial actions on the surface of the copper or the copper alloy. A surface treatment method for copper or a copper alloy according to the present invention comprises preparing a reducing agent solution containing a biological reducing substance, and treating the surface of the copper or the copper alloy with the reducing agent solution. The present invention also provides a surface treatment liquid for sterilizing copper or a copper alloy, in which the surface treatment liquid contains a biological reducing substance. The present invention also provides a sterilization method that comprises bringing copper or a copper alloy treated by the surface treatment method into contact with a surface of an object to sterilize the surface of the object.Type: ApplicationFiled: May 30, 2018Publication date: May 21, 2020Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Akiko YAMAMOTO, Keiichiro OISHI, Shinji TANAKA
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Publication number: 20200158701Abstract: In an LC/MS/MS analysis: injecting a sample into a passage leading to a column group provided in a liquid chromatograph, the column group including a plurality of columns serially connected to each other and packed with different kinds of packing materials; supplying an eluant to one or a plurality of columns including a column located most downstream, to separate a portion of the target components in the sample in the one or plurality of columns, and sequentially elute those components from the most downstream column to perform mass spectrometry; and supplying a different eluant to one or a plurality of columns including the most downstream column, to separate at least a portion of the target components which stayed uneluted in the one or plurality of columns in the first analysis step, and sequentially elute those components from the most downstream column to perform mass spectrometry.Type: ApplicationFiled: April 13, 2017Publication date: May 21, 2020Applicants: SHIMADZU CORPORATION, National Institute for Environmental StudiesInventors: Toshikazu MINOHATA, Jun WATANABE, Shoji NAKAYAMA
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Publication number: 20200156956Abstract: The present disclosure relates to a method for producing metal oxide nanoparticles includes a first step of preparing a reaction solution containing a metal complex, an alcohol, and water; a second step of heating the reaction solution for phase-separation under a hermetically sealed atmosphere where the volumetric expansion ratio of the reaction solution reaches 5 to 15%; a third step of holding the reaction solution heated in the second step for 30 minutes or more for dehydrating the metal complex to precipitate the metal oxide nanoparticles; and a fourth step of collecting the metal oxide nanoparticles after the metal oxide nanoparticles are cooled.Type: ApplicationFiled: January 23, 2020Publication date: May 21, 2020Applicants: FURUKAWA ELECTRIC CO., LTD., NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Yoshikazu TSUZUKI, Mariko WAKAE, Kazuhiko KURUSU, Hideki ABE
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Publication number: 20200162384Abstract: A network switching device includes: a communication unit; an information collection unit configured to obtain information on a network state of the network from first and second information for packets received through the communication unit; a marking reference calculation unit configured to calculate a marking reference based on the second information when it is determined that the network state has changed based on the first information; and a marking execution unit configured to perform marking indicating a congestion degree on at least a part of the packets received through the communication unit based on the calculated marking reference.Type: ApplicationFiled: October 29, 2019Publication date: May 21, 2020Applicant: Ulsan National Institute of Science and TechnologyInventors: Kyunghan LEE, Junseon KIM
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Publication number: 20200162389Abstract: A method, performed by a receiver, for controlling congestion, including receiving packets from a transmitter, determining a maximum transmission rate of the received packets; determining a minimum packet delay of the received packets; determining characteristics of a congestion window of next packets to be received from the transmitter based on the maximum transmission rate and the minimum packet delay; and transmitting information on the determined characteristics of the congestion window to the transmitter.Type: ApplicationFiled: November 18, 2019Publication date: May 21, 2020Applicant: Ulsan National Institute of Science and TechnologyInventors: Kyunghan LEE, Shinik PARK
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Publication number: 20200157082Abstract: The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.Type: ApplicationFiled: January 21, 2020Publication date: May 21, 2020Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, National Institutes of Health, A Component of the United States Department of Health and Human, The Regents of the University of CaliforniaInventors: Donna M. Huryn, Peter Wipf, Matthew G. LaPorte, Raffaele Colombo, Marina Kovaliov, Chaemin Lim, Celeste Natalie Alverez, Zhizhou Yue, Lalith Palitha Samankumara, Alexander Julian Chatterley, Yongzhao Yan, Mary Liang, Neal J. Green, Eric T. Baldwin, William J. Moore, Michelle Arkin, R. Jeffrey Neitz, Kean-Hooi Ang, Clifford Bryant, Stacie Bulfer