Patents Assigned to National Sun Yat-Sen University
  • Patent number: 9739602
    Abstract: A method using fringe projection to describe the three-dimensional profile of a specular object is presented and has steps of: providing a diffraction grating formed by exposing and developing a hologram and having at least two sets of interference fringes; guiding a conjugate of the reference light generated from a conjugate light source to pass through the diffraction grating, in order to generate a real image with a long depth of field, a wide convergent angle, and a sinusoidal distribution light intensity; projecting this real image onto an inspected specular object; using an image capture device to capture the intensity distribution of the real image on the inspected specular object so as to obtain an image signal; and using an image processor to analyze the image signal so as to identify the profile of the inspected specular object.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: August 22, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Wei-Hung Su, Bo-Chin Huang
  • Patent number: 9713602
    Abstract: The present invention relates to a method for increasing the oxygen release efficiency of a hemoglobin-based blood substitute by using a phthalide compound, comprising the steps of: administering to a subject in need thereof the phthalide compound or co-administering to the subject in need thereof the phthalide compound along with the hemoglobin-based blood substitute, wherein the phthalide compound has an effect of increasing the oxygen release efficiency of the hemoglobin-based blood substitute, wherein the hemoglobin-based blood substitute can be fetal hemoglobin (HbF) or other Hb variants retaining two native ? subunits. The phthalide compound is used to substitute for or cooperate with 2,3-BPG, to play a role of a 2,3-BPG substitute, to act on the hemoglobin-based blood substitute to effectively substitute the function of normal hemoglobin in releasing oxygen to tissue cells, in order to maintain the cellular oxygenation level within a normal range.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: July 25, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Chia-Chen Wang, Wei-Ren Chen
  • Patent number: 9707522
    Abstract: The invention discloses a biocompatible semi-permeable membrane. The semi-permeable membrane is manufactured by: providing an eggshell membrane; and immersing the eggshell membrane in an aqueous hydrogen peroxide solution with a concentration of 0.35 to 35% for 8 to 144 hours.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: July 18, 2017
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Patent number: 9711720
    Abstract: A resistive random access memory including a first electrode, a separating medium, a resistance changing layer and a second electrode is disclosed. The first electrode has a mounting face. The separating medium is arranged on the first electrode and forms a through hole. A part of the first electrode is not covered by the separating medium. The separating medium has a first dielectric. The resistance changing layer extends along the part of the first electrode as well as along an inner face and the second face of the separating medium. The resistance changing layer has a second dielectric having a dielectric constant larger than a dielectric constant of the first dielectric by 2 or less. The second electrode is arranged on the resistance changing layer. In this arrangement, the problem of unstable forming voltage of the conventional resistive random access memory can be solved.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: July 18, 2017
    Assignee: National Sun Yat-Sen University
    Inventors: Ting-Chang Chang, Kuan-Chang Chang, Tsung-Ming Tsai, Tian-Jian Chu, Chih-Hung Pan
  • Patent number: 9690164
    Abstract: An acousto-optic crystal optical waveguide is applicable to an acoustic wave sensor for sensing acoustic wave, wherein the acousto-optic crystal optical waveguide includes an acousto-optic crystal core and an inner cladding layer covering the acousto-optic crystal core. The acoustic wave is able to change the refraction index of the acousto-optical crystal optical waveguide to make a light beam with specific wavelength refracting to outside of the acousto-optic crystal waveguide when a light beam transmits through the acousto-optic crystal optical waveguide. Objective of acoustic wave sensing is achieved by detecting wavelength and intensity variation of the light beam transmits through the acousto-optic crystal optical waveguide.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: June 27, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Jau-Sheng Wang, Yung-Hsin Tseng
  • Patent number: 9685610
    Abstract: A method for producing a resistive random access memory includes preparing a first metal layer and sputtering a resistive switching layer on the first metal layer. Surface treatment is conducted on the resistive switching layer by using a plasma containing mobile ions to dope the mobile ions into the resistive switching layer. The polarity of the mobile ions is opposite to the polarity of oxygen ions. Then, a second metal layer is sputtered on the resistive switching layer.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: June 20, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Ting-Chang Chang, Kuan-Chang Chang, Tsung-Ming Tsai, Tian-Jian Chu, Chih-Hung Pan
  • Patent number: 9678082
    Abstract: The present invention relates to a method of traceless labeling glycoproteins on a surface and an application thereof. A test glycoprotein can be immobilized on a surface using a BA-tosyl probe and the BA-tosyl probe is then released using a releasing agent, so as to expose a glycan residue of the test glycoprotein. The exposed glycan residue of the test glycoprotein can be detected without altering native glycan structures. Moreover, the present invention further provides a detection kit of traceless labeling glycoproteins on a surface in the study of glycoprotein-protein interactions, which is suitable for using the aforementioned method.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: June 13, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Po-Chiao Lin, Yung-Lin Yang, Yen-Pin Lee
  • Patent number: 9676906
    Abstract: A polymer of poly(arylene ether)s, a manufacturing method thereof, and a polymer light emitting diode with an organic light emitting layer made from the polymer are provided. The polymer is formed by processing a nucleophilic polycondensation between a fluoro-containing monomer having an electron-withdrawing group and a multi-phenyl monomer. The polymer has a host portion with fluoro- or trifluoromethyl substituents, and a customer portion with multi-phenyl groups.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: June 13, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Wen-yao Huang, Hsu-feng Lee, Yi-chiang Huang, Mei-ying Chang, Tzu-sheng Huang, Hsin-yi Wen, Chih-chen Wu
  • Publication number: 20170157084
    Abstract: The present invention relates to a method for modulating angiogenesis in a subject in need thereof, which comprises administering an effective amount of composition comprising excavatolide B and a pharmaceutically acceptable carrier to the subject.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 8, 2017
    Applicant: National Sun Yat-sen University
    Inventors: ZHI-HONG WEN, PING-JYUN SUNG, HAN-CHUN HUNG
  • Patent number: 9644069
    Abstract: A polymer of fluorine-containing sulfonated poly(arylene ether)s and a manufacturing method thereof are provided. The polymer is formed by processing a nucleophilic polycondensation between a fluorine-containing monomer having an electron-withdrawing group and a multi-phenyl monomer. A main structure of the polymer of fluorine-containing sulfonated poly(arylene ether)s has a first portion with fluoro or trifluoromethyl substituted phenyl groups, and a second portion with sulfonated phenyl groups.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: May 9, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Wen-yao Huang, Hsu-feng Lee, Benjamin Britton, Chun-che Lee, Steven Holdcroft, Jun-jie Pang, Yi-yun Hsu, Yu-chao Tseng
  • Patent number: 9647020
    Abstract: A light sensing circuit for solving the problem of low reliability in illumination detection includes a photo transistor having a gate, a drain and a source; a first transistor electrically connecting between the gate and source of the photo transistor; a first capacitor electrically connecting between the gate and the drain of the photo transistor; a second transistor electrically connecting with the drain of the photo transistor, the first capacitor, and a data signal; a second capacitor electrically connecting between the source of the photo transistor and a ground contact; a third transistor electrically connecting with the photo transistor, the first transistor, and the second capacitor; and a switch adapted to alternatively connect the third transistor with a buffer or a zero signal. A control method of the above light sensing circuit is also disclosed. Therefore, the above identified problem can be surely solved.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: May 9, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Ting-Chang Chang, Hua-Mao Chen, Ming-Yen Tsai, Min-Chen Chen
  • Patent number: 9632951
    Abstract: A cache memory includes a tag memory array and a data memory array. A control register records a reconfiguration status of at least one cache way, a start address of the tag memory array, and a start address of the data memory array. A memory controller is electrically connected to the tag memory array, the data memory array, and the control register. The memory controller controls a data access state of the tag memory array according to the mode byte and the tag base address. The memory controller controls a data access state of the data memory array according to the mode byte and the data base address. A selection module is electrically connected between the tag memory array, the data memory array, and the memory controller. The cache memory solves the problem of idle tag memory of the tag memory array.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: April 25, 2017
    Assignee: National Sun Yat-Sen University
    Inventors: Ing-Jer Huang, Chun-Hung Lai, Yun-Chung Yang
  • Patent number: 9623077
    Abstract: The present invention relates to a method for alleviating pain in a subject in need thereof, which comprises administering an effective amount of piscidin (PCD) peptide and a pharmaceutically acceptable carrier to the subject.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: April 18, 2017
    Assignees: ACADEMIA SINICA, NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Zhi-Hong Wen, Jyh-Yih Chen
  • Patent number: 9620211
    Abstract: A maintaining device and a maintenance method for maintaining the normal operation of a resistive random access memory are disclosed. The maintenance method can be executed by the maintaining device. Said memory includes first and second electrodes. The first electrode is not grounded. The maintaining device is connected to the first electrode so that the first electrode receives an operational signal and a restoring signal generated by the maintaining device. The operational signal transits from a zero voltage to a non-zero voltage and then to the zero voltage. If the operational signal has already transited from the non-zero voltage to the zero voltage, the maintenance method controls the restoring signal to transit from the zero voltage to a negative voltage, controls the restoring signal to remain the negative voltage for a period of restoring time, and controls the restoring signal to transit from the negative voltage to the zero voltage.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: April 11, 2017
    Assignee: National Sun Yat-Sen University
    Inventors: Ting-Chang Chang, Kuan-Chang Chang, Tsung-Ming Tsai, Yu-Ting Su, Chih-Hung Pan
  • Publication number: 20170087222
    Abstract: The present invention relates to a method for treating pain in a subject in need thereof, comprising administering an effective amount of a nucleic acid to the subject, wherein the nucleic acid comprises a PTEN nucleotide sequence of SEQ ID NO: 1. The present invention also provides a method for screening pharmaceutical compositions having an anti-pain effect, wherein the pharmaceutical compositions can stimulate the upregulation of PTEN.
    Type: Application
    Filed: March 18, 2016
    Publication date: March 30, 2017
    Applicant: National Sun Yat-sen University
    Inventors: Zhi-Hong Wen, Ming-Hong Tai, Shi-Ying Huang, Chun-Sung Sung, Wu-Fu Chen, Chun-Hong Chen, Chien-Wei Feng, Han-Chun Hung, Hui-Min David Wang, Nan-Fu Chen
  • Patent number: 9603555
    Abstract: A motion/vibration detection system and method therefore are provided. The system includes a transmitter and a receiver. The transmitter includes a transmit/receive antenna unit and a first oscillator. The receiver includes a receiving unit and a demodulation unit. The transmit/receive antenna unit receives an output signal from the first oscillator and transmits a detection signal. The detection signal is reflected from at least one object under detection into a reflected detection signal, which is received by the transmit/receive antenna unit. The transmit/receive antenna unit injects the reflected detection signal into the first oscillator and accordingly the first oscillator is under a self-injection locking mode. The receiving unit receives the detection signal. The demodulation unit demodulates the detection signal received by the receiving unit into a baseband output signal, to extract at least one motion/vibration information of the objection under detection.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: March 28, 2017
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Tzyy-Sheng Horng, Fu-Kang Wang, Kang-Chun Peng
  • Patent number: 9607818
    Abstract: A multimode ionization device includes an electrospray unit, a charge generating unit, and a plasma supplying unit. The electrospray unit is configured to form an electrospray plume which travels along a traveling path. The charge generating unit is configured to permit a liquid electrospray medium to leave the electrospray unit as the electrospray plume. The plasma supplying unit can generate and guide a plasma plume to mix with the electrospray plume so as to obtain a plume combination in a confluent zone, and is oriented to permit at least one of analytes carried in the plume combination to travel to the receiving unit along a linearly-extending end zone of the traveling path.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: March 28, 2017
    Assignee: National Sun Yat-Sen University
    Inventor: Jentaie Shiea
  • Patent number: 9578604
    Abstract: A power-allocation method for scalable video transmission over MIMO system includes: encoding a video sequence into L layers; performing MCSs to the layers and estimating bit error rate or symbol error rate respectively for each of the layers after MCSs procedure based on channel quality feedbacks from the receiver side; performing power allocations of L sub-problems and obtaining candidate power allocation solution of each of the sub-problems respectively based on bit error rate or symbol error rate of each of the layers and derivative of bit error rate or symbol error rate of each of the layers; and choosing one of the candidate power allocation solution with the largest quality of experiences as the power allocation of the scalable video transmission over MIMO system. This invention considers transmission-error-rate of PHY layer and video coding structure of APP layer and optimizes quality of experiences at user end with cross-layer design.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: February 21, 2017
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Xiang Chen, Jenq-Neng Hwang, Chung-Nan Lee
  • Patent number: 9563015
    Abstract: An optical waveguide structure and a manufacturing method thereof are disclosed. The optical waveguide structure has a first waveguide layer, a binding layer, and a second waveguide layer. The first waveguide layer has a taper portion, a connecting portion, and a strip portion. The manufacturing method of the optical waveguide structure has steps of etching to form the first waveguide layer, and then etching to form the second waveguide layer under the first waveguide layer.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: February 7, 2017
    Assignee: National Sun Yat-sen University
    Inventors: Yi-Jen Chiu, Yi-Jhe Chen, Chung-Yi Lin, Wei Lin
  • Patent number: 9559422
    Abstract: The disclosure provides a communication device. The communication device includes a ground conductor portion and a multi-antenna system. The multi-antenna system includes at least a first and a second resonant portion, each of which is disposed on the corresponding radiating edge of the ground conductor portion. Each of the resonant portions may have a loop resonant structure or may have an open-slot resonant structure, and has a resonant path. The electrically coupling portion makes the length of the resonant path less than or equal to 0.18 times the wavelength of the lowest operating frequency of the multi-antenna system, and thereby excites the corresponding radiating edge and forms a strong surface current distribution, and generates an effective radiating energy and at least one resonant mode, in which the effective radiating energy has a corresponding strongest radiation direction.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: January 31, 2017
    Assignees: Industrial Technology Research Institute, National Sun Yat-sen University
    Inventors: Kin-Lu Wong, Yeh-Chun Kao, Po-Wei Lin, Wei-Yu Li