Patents Assigned to National Taiwan University
  • Publication number: 20150147722
    Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a flexible portion having at least one trench. The trench is disposed on the surface of the flexible portion and has a first end and a second end. An interval is disposed between the first end and the second end. The trench is disposed for spreading the stress applied on the bionic fixing apparatus and preventing stress concentration and stress shielding.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Applicants: NATIONAL TAIWAN UNIVERSITY HOSPITAL, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Pei-Yi TSAI, Chih-Chieh HUANG, Yi-Hung WEN, Hsin-Hsin SHEN, Yi-Hung LIN, De-Yau LIN, Jui-Sheng SUN, Chuan-Sheng CHUANG, An-Li CHEN, Ching-Chih LIN
  • Publication number: 20150147632
    Abstract: An electrolyte composition including a lithium salt (A), an first anion (B1) represented by formula (1), and an organic solvent (C) are provided. When the electrolyte composition is applied in a lithium battery, good structural stability, high battery efficiency, and long charge-discharge cycle life of the lithium battery can be achieved.
    Type: Application
    Filed: May 25, 2014
    Publication date: May 28, 2015
    Applicant: National Taiwan University of Science and Technology
    Inventors: Fu-Ming Wang, Sylvia Ayu Pradanawati
  • Patent number: 9039622
    Abstract: An image generation system is provided, the system generating an ultrasound image and a photo-acoustic image of an object and including a dual-wavelength laser source, an optical filter, and an optical-based ultrasound sensor. The laser source generates a first laser pulse with a first wavelength or a second laser pulse with a second wavelength. The optical filter almost completely absorbs the energy of the first laser pulse and by the photo-acoustic effect, generates and transmits an ultrasound to the object so the object scatters and reflects the ultrasound. The second laser pulse almost completely penetrates the optical filter and is transmitted to the object so the object absorbs the energy of the second laser pulse, generates and sends a photo-acoustic signal. The optical-based ultrasound sensor receives the ultrasound and the photo-acoustic signal to generate the ultrasound image and the photo-acoustic image of the object.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: May 26, 2015
    Assignee: National Taiwan University
    Inventors: Pai-Chi Li, Bao-Yu Hsieh
  • Publication number: 20150137429
    Abstract: The present invention provides a fabrication method of a three dimensional micro-structure on polymers. The fabrication method of the present invention comprises the following steps of: preparing a sacrifice material; micro-processing the sacrifice material to form a pattern with micro-features; putting the sacrificed material with the micro-features into a mold and injecting a liquid state polymer into the mold; and solidifying the polymer by using a predetermined process and removing the sacrificed material through a guiding channel to create a three dimensional micro-structure on polymers.
    Type: Application
    Filed: April 28, 2014
    Publication date: May 21, 2015
    Applicant: National Taiwan University of Science and Technology
    Inventor: Chun-Hui Chung
  • Publication number: 20150140659
    Abstract: A three-dimensional cell culture system for an imaging system to observe a cell image includes at least two cell culture layers formed by a solution having a photo-polymerizable monomer, a bio-molecule, an acoustic scattering medium solution and a cell culture medium. After placing a cell into the two cell culture layers, the two cell culture layers are laminated to form a three-dimensional culture laminating layer for culturing the cell. After forming the three-dimensional culture laminating layer, at least one cell-locating layer having a polyethylene glycol diacrylate (PEGDA) solution, the acoustic scattering medium solution, a plurality of photoacoustic markers and the cell culture medium is positioned into the three-dimensional culture laminating layer so as to form the three-dimensional cell culture system. The imaging system is constructed according to a theory selected from one of optics, acoustics, optoacoutics and acousto-optics.
    Type: Application
    Filed: March 13, 2014
    Publication date: May 21, 2015
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: PAI-CHI LI, PO-LING KUO, CHIN-HSIUNG TSAI
  • Publication number: 20150141485
    Abstract: The present invention provides a method for the prognosis of lung cancer patient based on the expression levels of miRNA-135b, LZTS1, LATS2 and nuclear TAZ. The invention also provides a method for treatment of lung cancer.
    Type: Application
    Filed: November 20, 2013
    Publication date: May 21, 2015
    Applicants: NATIONAL CHENG KUNG UNIVERSITY, NATIONAL TAIWAN UNIVERSITY
    Inventors: Pan-Chyr Yang, Ching-Wen Lin, Tse-Ming Hong, Yih-Leong Chang
  • Publication number: 20150141783
    Abstract: A biomedical signal sensing circuit including a first and a second modulation unit, an amplifying unit, a first and a second demodulation unit is provided. The first modulation unit performs a first modulation operation to a first biomedical signal according to a first signal to generate a first modulation signal. The second modulation unit performs a second modulation operation to a second biomedical signal according to a second signal to generate a second modulation signal. The amplifying unit amplifies the first and second modulation signals, and adds the amplified first and second modulation signals to generate a third modulation signal. The first demodulation unit performs a first demodulation operation to the third modulation signal according to the first signal to generate a first sensing signal. The second demodulation unit performs a second demodulation operation to the third modulation signal according to the second signal to generate a second sensing signal.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 21, 2015
    Applicant: National Taiwan University
    Inventors: Yi-Lin Tsai, Fong-Wen Lee, Chih-Chan Tu, Bang-Cyuan Wang, Tsung-Hsien Lin
  • Publication number: 20150143494
    Abstract: The present invention provides a continuous identity authentication method. This method transforms the behavior records of different time intervals of the system user into a text format, and uses a resampling technique to generate a large number of articles of different lengths in order to have behavior records of the system user in different lengths of time, then using a document classification technique to build a matrix. In the end, building behavioral models of different time periods of the system's user using Minimum Enclosing Ball technology. The behavioral models can then learn the behavior of the legitimate system user and continuously check whether the system is currently operated by the legitimate system user or not.
    Type: Application
    Filed: May 28, 2014
    Publication date: May 21, 2015
    Applicant: National Taiwan University of Science and Technology
    Inventors: Yuh-Jye Lee, Chi-Tien Yeh, Chien-Yi Chiu
  • Patent number: 9032821
    Abstract: Disclosed herein are improved articles for screening candidate insect pest-repellents; and their uses in host-free methods and/or systems for screening candidate insect pest-repellents.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: May 19, 2015
    Assignee: National Taiwan University
    Inventors: Wen-Jer Wu, Rong-Nan Huang, Li-Chong Su
  • Publication number: 20150131719
    Abstract: A rate-distortion optimized quantization method includes determining a rate model and a distortion model respectively, establishing a rate-distortion objective function according to the rate model and the distortion model, estimating a closed-form solution for the rate-distortion objective function, and according to an input frame generating quantized transform coefficients using the closed-form solution.
    Type: Application
    Filed: January 13, 2014
    Publication date: May 14, 2015
    Applicant: National Taiwan University
    Inventors: Tsung-Yau HUANG, Homer H. CHEN, Chieh-Kai KAO
  • Patent number: 9030746
    Abstract: The present invention discloses a fabrication method of a microlens array (MLA) and an MLA fabricated using the same. The fabrication method of an MLA comprises: providing a substrate with an interface hydrophilic modified polymer layer; using light, gas or liquid with the property of converting the polymer' hydrophilicity to create a hydrophilic zone on the interface hydrophilic modified polymer layer; coating the substrate with a liquid material to condense a plurality of liquid microlenses in the hydrophilic zone; and curing the plurality of liquid microlenses to form a plurality of microlenses. Therefore, the fabrication method of an MLA has advantages of fast speed, low cost, no etch transfer and low temperature.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: May 12, 2015
    Assignee: National Taiwan University
    Inventors: Hsiang-Chun Wei, Guo-Dung Su
  • Publication number: 20150125855
    Abstract: The present invention provides a method of SNP detection by using gene detection in bead-based microfluidics comprising following steps: (a) preparing a microbead with a duplex DNA; (b) inserting a dye into the duplex DNA; (c) delivering the microbead into a microchannel with a temperature gradient region; (d) heating the temperature gradient region to denature the duplex DNA; (e) monitoring a fluorescence intensity of the duplex DNA during the step (d) to obtain a melting curve; and (f) determining the SNP by a melting curve analysis method; wherein the duplex DNA is synthesized by a target single-strand DNA and an allele-specific probe. Furthermore, the present invention offers a temperature gradient region to enhance the measurement accuracy. The continuous-flow mechanism in this region is validated and optimized.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 7, 2015
    Applicant: National Taiwan University
    Inventors: Kan-Chien LI, Shih-Torng DING, En-Chung LIN, Yen-Wen LU
  • Publication number: 20150117734
    Abstract: A method of ultrasound nonlinear imaging with high-bit Golay code excitation includes transmitting a first, a second, a third and a fourth Golay code signal wave which have more than four bits and are orthogonal pairs to each other; making the second and the forth Golay code signal wave be subtracted from the first and the third Golay code signal wave respectively to eliminate noise interference wave; performing compression filtering process to the above generated waves and taking a cross sum to generate two compressed code waves; taking the difference between the two compressed code waves to generate an image wave which includes at least two second-order harmonic waves; processing ultrasound nonlinear imaging by using the second-order harmonic waves and to generate an ultrasound image.
    Type: Application
    Filed: March 5, 2014
    Publication date: April 30, 2015
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventor: CHE-CHOU SHEN
  • Publication number: 20150118649
    Abstract: The present invention relates to a surface treatment method for an implant, comprising: providing an implant; and forming a ceramic layer on a surface of the implant by atomic layer deposition, wherein the ceramic layer has a thickness of 5-150 nm; a root mean square roughness increase in a range of 15 nm or less; and a friction coefficient of 0.1-0.5. The ceramic layer formed on the surface of the implant can fully encapsulate the surface of the implant with excellent uniformity to effectively block the free metal ions dissociated from the implant. Moreover, it has anti-oxidation and anti-corrosion effects, and greatly enhances the biocompatibility of the implant.
    Type: Application
    Filed: May 20, 2014
    Publication date: April 30, 2015
    Applicant: National Taiwan University
    Inventors: Sheng-Hao HSU, Wan-Yu TSENG, Li-Deh LIN, Ming-Shu LEE, Ming-Hung TSENG, Wei-Fang SU, Feng-Yu TSAI, Min-Huey CHEN
  • Publication number: 20150119716
    Abstract: A method of ultrasound nonlinear imaging with Golay code excitation includes transmitting a first and a second Golay code signal wave which are orthogonal by each other; making the second Golay code signal wave be subtracted from the first Golay code signal wave to eliminate a first and a second noise interference wave to generate a third Golay code signal wave; using a first and a second compression filter to process the third Golay code signal wave to generate a first and a second compressed code signal wave; taking the difference between the first compressed code signal wave and the second compressed code signal wave to generate a third compressed code signal wave which includes at least two second-order harmonic waves; processing ultrasound nonlinear imaging by using the multi-frequency harmonic component waves to generate an ultrasound image.
    Type: Application
    Filed: March 5, 2014
    Publication date: April 30, 2015
    Applicant: National Taiwan University
    Inventor: CHE-CHOU SHEN
  • Patent number: 9020252
    Abstract: An image recognition method and an image recognition system can be applied to fetal ultrasound images. The image recognition method includes: (a) adjusting the image with a filter operator to decrease noise and to homogenize an image expression level of the pixel units within an individual object structure; (b) analyzing the image by a statistic information function, determining a foreground object pixel unit and a background pixel unit according to a max information entropy state of the statistic information function; and (c) searching by a profile setting value and recognizing a target object image among the foreground object pixel unit. The image recognition method can not only increase the efficiency of identifying the object of interests within the image and measuring the object of interests, but also improve the precision of measurements of the object of interests.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 28, 2015
    Assignee: National Taiwan University of Science and Technology
    Inventor: Ching-Wei Wang
  • Patent number: 9018820
    Abstract: The present invention relates to an integral or a non-integral stator structure for reducing the manufacturing complexity by eliminating the boot part of the tooth part thereof. The stator structure is made of a core material, and includes: a plurality of stator units, each having a tooth part and an annular part, in which different stator units can be connected with each other integrally or non-integrally, so as to form an annular stator structure. The tooth part of each stator unit is formed in a pillar shape that has a first end and a second end, and the first end is connected to the annular part.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: April 28, 2015
    Assignee: National Taiwan University of Science and Technology
    Inventors: Jonq-Chin Hwang, Chun-Yu Hsiao, Sheng-Nian Yeh
  • Patent number: 9019601
    Abstract: A light harvesting lens module for collecting an ambient light includes a plurality of annular lenses. The annular lenses are arranged in order from center to outside to form a disc-structure. Each annular lens has a light-input curved surface and a light-output curved surface. The light-input curved surface is in opposition to the center. The light-output curved surface is in opposition to the light-input curved surface, and faces the center. The light is incident on the light-input curved surface, and is refracted and tend to concentrate by the light-input curved surface. Then, the light is emitted from the annular lens, and is refracted to the direction of the center by the light-output curved surface. The ambient light is able to be compressed into a point light by the lens module, so as to increase the concentration ratio and the compression ratio to further get the effective advantage.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: April 28, 2015
    Assignee: National Taiwan University of Science and Technology
    Inventors: Wei-Che Hsieh, Allen Jong-Woei Whang, Yi-Yung Chen
  • Patent number: 9017657
    Abstract: The invention relates to a cell culture method, particularly to a co-culture method for human mesenchymal stem cells and target animal cells, in order to solve the problem that animal cells are not easy to survive alone upon culturing. The invention also provides a method for using a stem cell conditioned medium to culture animal cells. The invention also provides a method to induce the transformation of human fetal islet-like cell clusters from human stem cells and its application thereof.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: April 28, 2015
    Assignee: National Taiwan University
    Inventors: Shing-Hwa Liu, Kuo-Ching Chao, Kuo-Fang Chao
  • Publication number: 20150111226
    Abstract: The present invention provides a method of peptide histochemical diagnosis to detect the peptide binding protein in the cancer tissue. This peptide binding specifically to tumor cells is linked to the dextran coated iron oxide nanoparticle. The peptide linked dextran coated iron oxide nanoparticle can be used to bind to the formalin-fixed and paraffin-embedded tumor surgical specimens, and the method of present invention can be used to evaluate the efficacy of peptide-targeted chemotherapy for treatment of cancer patients.
    Type: Application
    Filed: January 27, 2014
    Publication date: April 23, 2015
    Applicant: National Taiwan University
    Inventors: Chin-Tarng Lin, Han-Chung Wu