Abstract: The present invention provides, a cationic lipid represented by the formula (1) (wherein each symbol is as defined in the specification), a lipid membrane structure using the aforementioned cationic lipid, a nucleic acid-introducing agent using the aforementioned cationic lipid, and a method for introducing a nucleic acid by using the aforementioned nucleic acid-introducing agent.

Abstract: A transgenic plant which exhibits a growth capacity which is enhanced compared to that of a host plant, and has a chimeric protein of a peptide containing an amino acid sequence derived from a motor domain of myosin XI of a donor plant 1, which is a plant species other than the host plant, and a peptide containing an amino acid sequence derived from a domain other than the motor domain of myosin XI of a donor plant 2, which is the host plant or a plant species other than the host plant, the transgenic plant being characterized in that the motor domain loop 2 region has EEPKQGGKGGGKSSFSSIG or EEPKQGGGKGGSKSSFSSIG, and in addition to these sequences, has an amino acid sequence in which one to six amino acids have been deleted, replaced or added.

Abstract: A layer configuration prediction method is provided and includes: a specimen production step of producing multiple specimens by depositing layers of a material in configurations different from each other; a specimen measurement step of performing, on each specimen, measurement to acquire a texture parameter corresponding to a texture; a learning step of causing a computer to perform machine learning of a relation between each of the specimens and the texture parameter; a setting parameter calculation step of calculating a setting parameter corresponding to the texture set to a computer graphics image; and a layer configuration acquisition step of providing the setting parameter as an input to the computer having been caused to perform the machine learning, and acquiring an output representing the layering pattern of layers of the material corresponding to the setting parameter.

Abstract: The problem that differences among lots in components and amounts of growth factors and the like in platelet-rich plasmas derived from an autologous plasma and the freeze-dried preparations thereof are large, and the effects of the lots are not kept constant is solved. Specifically, a freeze-dried preparation comprising megakaryocytes and platelets induced to differentiate from stem cells, a pharmaceutical composition comprising the freeze-dried preparation, and the like are provided.

Abstract: The objective of the present invention is to provide a particle detection device and a particle detection method that can individually and continuously detect a wide range of particles. The objective is achieved by a particle detection device including: a particle separation channel through which particles are separated according to particle sizes in a perpendicular direction to the flow of fluid; and two or more particle recovery channels that are connected to and branched from the particle separation channel, in which each of the particle recovery channels includes a particle detection unit that includes an aperture and an electric detector.

Abstract: An object of the present invention is to provide a method for efficiently producing a heparin-like substance without using an animal-derived tissue. The present invention relates to a method for producing a heparin-like substance and the like, the method comprising: (1) preparing a mammalian cell that produces a heparin-like substance, (2) preparing a recombinant cell in which a gene that encodes an extracellular domain of syndecan is introduced into the mammalian cell that produces a heparin-like substance and is prepared in step (1), and (3) culturing the recombinant cell prepared in step (2) in a medium and collecting the heparin-like substance from the resulting culture supernatant.

Abstract: There is provides a biological condition determining apparatus for determining a biological condition of a subject on a bed. A biological condition determining apparatus includes a plurality of load detectors which are placed in the bed or under feet of the bed and which detect a load of the subject, a biological information extracting unit which extracts biological information from an output of at least one of the load detectors, a determining unit which determines the biological condition of the subject by comparing the extracted biological information with a referential information prepared beforehand, and an output unit which outputs the biological condition of the subject determined by the determining unit.

Abstract: A liquid composition contains a thiophene polymer and a solvent, and the difference |?p2??p1| is 7.7 MPa0.5 or more and 13.4 MPa0.5 or less between a dipole-dipole force term ?p1 of Hansen solubility parameter of the thiophene polymer and a dipole-dipole force term ?p2 of Hansen solubility parameter of the solvent.

Abstract: A lyophilized composition capable of encapsulating any nucleic acid with high efficiency and easily is provided. A lyophilized composition of lipid nanoparticles not containing a nucleic acid but containing an ionic lipid, a sterol, a PEG lipid, an acidic buffer component that shows a buffering action at pH 1-6, and a cryoprotectant, wherein a weight ratio of the cryoprotectant and a total lipid is 10:1-1000:1.

Abstract: Provided is a novel technique for treating cancer using structurally-reinforced S-TuD. Provided are: a composition for the prevention or treatment of tumors, said composition comprising an miRNA inhibitory complex including RNA of analog thereof; and a method for preventing or treating tumors using said composition. The miRNA inhibitory complex preferably includes at least one double-stranded structure and an miRNA-binding sequence. Two strands of the miRNA binding sequence preferably bind individually to two strands on at least one end of the double-stranded structure. According to some of the aspects of the present invention, there is provided a delivery system for delivering such an miRNA inhibitory complex.

Abstract: An information processing apparatus includes circuitry and a memory, the circuitry performing perceptual image conversion of converting two image data generated from one color image data respectively into perceptual images based on human visual characteristics, collation of determining whether the two perceptual images converted by the perceptual image conversion are same, and comparison result outputting of outputting the comparison result by the collation.

Abstract: In this control apparatus design method, a feedback control system comprises a generalization plant including a nominal plant N representing the input/output characteristic of an object to be controlled and a fluctuation unit ? for making at least one model parameter included in the nominal plant N fluctuate, and a controller for applying input to the generalization plant P on the basis of output from the generalization plant P. The controller is designed so as to satisfy a prescribed design condition. The nominal plant N comprises a nominal value multiplication unit for multiplying an input signal ? by a nominal value for the model parameter and an addition unit for adding a fluctuation output signal ? from the fluctuation unit ? and an output signal from the nominal value multiplication unit. Further, the fluctuation unit ? generates the fluctuation output signal ? using a mapping ?p obtained from a Cayley transform of unbounded complex fluctuation ?g.

Abstract: Objects of the present invention are to find a marker by which progression of arteriosclerosis can be directly grasped, to thereby provide motivation for prevention or treatment of arteriosclerosis itself, and to provide means for accurately grasping condition of arteriosclerosis-related disease including arteriosclerotic disease. The invention provides a method for acquiring data on progression of arteriosclerosis, the method including determining a level of an antibody against SH3BP5 protein or a part thereof in a body fluid sample collected from a biological body, and a data acquisition kit for performing the data acquisition method.

Abstract: A medical information providing system 1 includes a medication examination information extracting unit 21d and a database management unit 21e in a medication examination DB server 20. The medication examination information extracting unit 21d extracts information on clinical examination relating to a medication that requires clinical examination when it is prescribed from at least one of package insert data and prescription guideline data concerning functional decline of internal organs, for plural types of medications. In addition, the medication examination information extracting unit 21d generates a medication examination database in which the extracted clinical examination information on the medication and the medication are stored in association with each other.

Abstract: The invention provides a cationic lipid, a lipid membrane structure containing same, and use thereof. The cationic lipid is represented by the formula (1) wherein R1a, R1b, R2a, R2b, R3a, R3b, Xa, Xb, Yb, Za, and Zb are as defined in the specification.

Abstract: A liquid composition includes a thiophene polymer; and at least one polymerization component selected from the group including a monomer and an oligomer.

Abstract: A resonance oscillator circuit is provided to include first and second oscillators. The first oscillator includes a first LC resonator circuit and an amplifier element, and oscillates by shifting a phase of an output voltage with a predetermined phase difference and feeding the output voltage back to the amplifier element. The second oscillator oscillates by generating a gate signal, which has a frequency identical to that of the output voltage, and drives the amplifier element, by shifting the phase of the output voltage with the phase difference and feeding the gate signal back to an input terminal of the amplifier element, by using the amplifier element as a switching element and using the first oscillator as a feedback circuit. The phase difference is a value substantially independent of an inductance of the first LC resonator circuit and a load, to which the output voltage is applied.

Abstract: An image processing apparatus includes a processor including hardware. The processor is configured to: acquire video data; estimate a spatial distribution of a predetermined biological component for which a component spectrum temporally varies with respect to image data of a predetermined frame among a plurality of frames included in the video data; generate biological component video data in which the biological component is extracted from the video data based on the estimated spatial distribution of the biological component in the image data of the predetermined frame; and generate periodic variation video data of the biological component by applying, to the biological component video data, a filter for extracting a predetermined frequency component.

Abstract: Tumor growth was found to be significantly suppressed in vivo by inhibiting both miRNA containing 5?-AACACUG-3? as a seed sequence and miRNA containing 5?-AAUACUG-3? as a seed sequence. The inhibition significantly altered the proportion of subpopulations of tumor cells and reduced the tumorigenicity in all subpopulations. The inhibition also exerted a remarkable tumor-shrinking effect on already-formed tumors. The present invention provides novel therapeutic potential against tumor.

Abstract: An information processing apparatus includes circuitry and a memory, the circuitry performing perceptual image conversion of converting two image data generated from one color image data respectively into perceptual images based on human visual characteristics, collation of determining whether the two perceptual images converted by the perceptual image conversion are same, and comparison result outputting of outputting the comparison result by the collation.