Patents Assigned to National University Corporation Kagawa University
  • Publication number: 20210386767
    Abstract: To provide a brown and beige adipocyte activating agent and a brown and beige adipocyte activating food, each containing D-allulose as an active ingredient. Provided are a brown and beige adipocyte activating agent containing D-allulose as an active ingredient; a brown and beige adipocyte activating agent containing at least D-allulose and having a UCP-1 expression promoting action; a brown and beige adipocyte activating agent which enhances UCP-1 expression and thereby activates brown and beige adipocytes; an energy consumption promoting agent containing D-allulose as an active ingredient; an energy consumption promoting agent which activates brown and beige adipocytes and thereby promotes energy consumption; a UCP-1 expression enhancing agent containing D-allulose as an active ingredient; and a composition or food composition containing these agents.
    Type: Application
    Filed: November 7, 2019
    Publication date: December 16, 2021
    Applicant: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Koji Murao, Hitomi Imachi, Ken Izumori, Akihide Yoshihara
  • Publication number: 20210324434
    Abstract: An object of the present invention is to provide a rare sugar-containing composition having improved properties as a sweetener while maintaining the excellent functionality of D-psicose. The invention relates to a method of producing a rare-sugar containing composition with D-fructose as a raw material. An intended product having a novel composition of D-glucose, D-fructose, and D-psicose is obtained by preparing a mixture of D-fructose and D-psicose by using ketose 3-epimerase in the first stage and converting D-fructose into D-glucose by using D-xylose isomerase inert to D-psicose in the second stage. The first-stage product is a mixture of D-fructose and rare sugar D-psicose. The resulting mixture is a sweetener having a taste quality equal to that of sugar.
    Type: Application
    Filed: November 7, 2019
    Publication date: October 21, 2021
    Applicant: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Kazuya Akimitsu, Ken Izumori, Seizo Takaoka, Akihide Yoshihara, Shiro Kato, Susumu Mochizuki
  • Patent number: 11039576
    Abstract: To provide a vascular sap measurement sensor in which a flow channel that receives incoming flow of vascular sap is unlikely to be blocked by tissues of a plant. A vascular sap measurement sensor 1 includes: a trapping probe 20 for trapping vascular sap; and a support 10 that supports the trapping probe 20. A trapping flow channel 21 that receives incoming flow of the vascular sap is formed in the trapping probe 20. The trapping flow channel 21 has an inlet opening 24 formed on a side surface of the trapping probe 20. This makes it unlikely that the trapping flow channel 21 will be blocked by tissues of a plant when sticking the trapping probe 20 into the plant.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: June 22, 2021
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Fusao Shimokawa, Akihito Ono, Hidekuni Takao, Kyohei Terao, Tsuyoshi Kobayashi, Ikuo Kataoka
  • Patent number: 11035782
    Abstract: A light source, a standing wave forming unit, a detector, and an absorbance calculating unit. The light source irradiates a sample with light. The standing wave forming unit forms, in the sample, an acoustic standing wave perpendicular to a surface of the sample. A node of the acoustic standing wave is positioned at a predetermined distance from the surface of the sample, the light from the light source entering the surface of the sample. The detector detects light emitted from the surface of the sample, and is disposed on the surface of the sample on a side where the light source is disposed. The absorbance calculating unit obtains absorbance.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: June 15, 2021
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventor: Ichiro Ishimaru
  • Patent number: 10935563
    Abstract: To provide a vascular sap flow speed sensor having a size allowing measurement of the flow speed of vascular sap in a part of a plant such as a stem and capable of being manufactured at low cost. A vascular sap flow speed sensor 1 includes a heater sensor HS and a reference sensor RS. The heater sensor HS includes: a first probe unit 10a including a heat transfer plate 11 and a probe 12; a heater 20; a first temperature sensor 30a; and a first housing 40a in which the heat transfer plate 11, the heater 20, and the first temperature sensor 30a are housed. The reference sensor RS includes: a second probe unit 10b including a heat transfer plate 11 and a probe 12; a second temperature sensor 30b; and a second housing 40b in which the heat transfer plate 11 and the second temperature sensor 30b are housed. Each of the first probe unit 10a and the second probe unit 10b is made of a metallic material.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: March 2, 2021
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Fusao Shimokawa, Kyosuke Nakada, Hidekuni Takao, Kyohei Terao, Hidenori Yoshimura, Hiroki Ishizuka, Tsuyoshi Kobayashi, Ikuo Kataoka
  • Publication number: 20210030037
    Abstract: A D-psicose-containing sweetener with the modification of the taste of D-psicose includes D-psicose, a sugar alcohol and/or a high intensity sweetener, preferably containing D-psicose as the main component, particularly a low-calorie sweetener and/or a sweetener giving refreshing feel in the oral cavity, as well as foods and drinks obtained by using the D-psicose-containing sweetener with the modification of the taste of D-psicose, and other products given with sweetness. The sugar alcohol is one or more sugar alcohols selected from the group consisting of sorbitol, mannitol, lactitol, maltitol, xylitol and erythritol, while the high intensity sweetener is one or more high intensity sweeteners as selected from aspartame, acesulfame K, sodium cyclamate, sodium saccharin, Sucralose (under trade name), stevia sweetener, dulcin, taumatin, neotame and monellin.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 4, 2021
    Applicants: MATSUTANI CHEMICAL INDUSTRY CO., LTD., NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Hideki Fujihara, Kazuhiro Okuma, Tetsuo Iida, Ken Izumori, Masaaki Tokuda, Kazuhiro Fukada
  • Publication number: 20200333128
    Abstract: Optical measuring apparatus includes: a light source irradiating an object to be measured; a splitter splitting transmitted light or reflected light from the object to be measured; a phase changer changing a phase of a first light which is one of the lights split; a phase fixer maintaining a phase of a second light which is the other light split; a multiplexer multiplexing lights output from the phase changer and the phase fixer; a detector detecting the light (interference image) output from the multiplexer; and a controller that extracts a reference point from the interference image, when a displacement of the reference point is detected, corrects a luminance value for each pixel of the interference images in accordance with a displacement of the object to be measured indicated by a displacement of the reference point, constructs an interferogram based on the luminance value for each pixel of the interference images after the correction.
    Type: Application
    Filed: October 30, 2018
    Publication date: October 22, 2020
    Applicants: NEC CORPORATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Takeshi AKAGAWA, Masahiro KUBO, Katsumi ABE, Ersin ALTINTAS, Yuji OHNO, Tetsuri ARIYAMA, Ichiro ISHIMARU
  • Publication number: 20200284717
    Abstract: A light source, a standing wave forming unit, a detector, and an absorbance calculating unit. The light source irradiates a sample with light. The standing wave forming unit forms, in the sample, an acoustic standing wave perpendicular to a surface of the sample. A node of the acoustic standing wave is positioned at a predetermined distance from the surface of the sample, the light from the light source entering the surface of the sample. The detector detects light emitted from the surface of the sample, and is disposed on the surface of the sample on a side where the light source is disposed. The absorbance calculating unit obtains absorbance.
    Type: Application
    Filed: August 18, 2017
    Publication date: September 10, 2020
    Applicant: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventor: Ichiro ISHIMARU
  • Patent number: 10638752
    Abstract: A composition comprising at least one monosaccharide selected from D-tagatose, D-allose, D-psicose, D-talose, D-sorbose, D-galactose, Lfructose, D-mannose and D-mannitol as an active ingredient and multiple surfactants selected from an anionic surfactant selected from aryl sulfonates, formalin condensates of aryl sulfonates, alpha-olefin sulfonates, alkyl sulfonates, alkyl diphenyl ether disulfonates, polyoxyethylene alkyl phenyl ether sulfonates, polyoxyethylene alkyl ether sulfosuccinic acid half esters, alkyl sulfates, sulfosuccinates, polyoxyalkylene aryl ether sulfates, polyoxyalkylene alkyl ether sulfates, polyoxyethylene-polyoxypropylene block polymer sulfates, polyoxyalkylene alkyl ether acetates, polyoxyalkylene aryl ether phosphates, polyoxyalkylene alkyl ether phosphates, polyoxyethylene-polyoxypropylene block polymer phosphates, alkyl phosphate esters, methyl taurates, polycarboxylates and fatty acid salts, wherein the anionic surfactants are at a blending ratio of 0.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: May 5, 2020
    Assignees: MITSUI CHEMICALS AGRO, INC., NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Toshiaki Ohara, Kiyoko Tanaka, Shuji Ishizaki, Shigehiro Kato, Kazuya Akimitsu, Ken Izumori
  • Patent number: 10545016
    Abstract: A light measurement device that maintains high measurement precision. The light measurement device includes: light source that irradiates light upon measurement object; branch part that splits transmitted light or reflected light from measurement object; phase-changing unit that changes the phase of one beam of the branched light beams; phase-fixing unit that maintains the phase of the other beam of the branched light beams; adjustment mechanism, which is provided in phase-changing unit or phase-fixing unit, for adjusting the propagation direction of light; multiplexer that causes the light emitted by each of phase-changing unit and phase-fixing unit to interfere with each other; detection unit that detects light that is interfered with by multiplexer; and control unit that controls the adjustment mechanism on the basis of the luminance values of an interference image that is detected by detection unit and adjusts the propagation direction of light in phase-changing unit or phase-fixing unit.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: January 28, 2020
    Assignees: NEC CORPORATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Takeshi Akagawa, Masahiro Kubo, Katsumi Abe, Kimiyasu Takoh, Ersin Altintas, Yuji Ohno, Tetsuri Ariyama, Ichiro Ishimaru
  • Patent number: 10519213
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: December 31, 2019
    Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, OCHSNER CLINIC FOUNDATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Robert C. Gensure, Joshua Sakon, Osamu Matsushita, Tulasi Ponnapakkam
  • Publication number: 20190338010
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 7, 2019
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, OCHSNER CLINIC FOUNDATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Robert C. Gensure, Joshua Sakon, Osamu Matsushita, Tulasi Ponnapakkam
  • Patent number: 10391286
    Abstract: [Subjects] To provide a biliary tract drainage tube in which both an external drainage tube and an internal drainage tube can be installed in a single endoscopic procedure. [Method to Solve] A biliary tract drainage tube used to drain a biliary tract is provided with long external drainage tube 2 and internal drainage tube 3 that is provided on the tip of the external drainage tube so as to be separable from the external drainage tube. Both external drainage tube 2 and internal drainage tube 3 are placed in biliary tract Cd. Since internal drainage tube 3 can be left behind in the biliary tract by removing external drainage tube 2, another endoscopic procedure is not required when switching from external drainage tube 2 to internal drainage tube 3, and the burden placed on the patient can be lessened.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: August 27, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventor: Hideki Kamada
  • Patent number: 10386236
    Abstract: Reflected light detecting device and method with surface reflected light components collectively be extracted/removed when detecting reflected light arising in casting light onto target-object range having non-planar surface.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: August 20, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Hiroki Hayashi, Ichiro Ishimaru
  • Patent number: 10358471
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: July 23, 2019
    Assignees: The Board of Trustees of the University of Arkansas, Ochsner Clinic Foundation, National University Corporation Kagawa university
    Inventors: Robert C. Gensure, Joshua Sakon, Osamu Matsushita, Tulasi Ponnapakkam
  • Publication number: 20190204065
    Abstract: A light measurement device that maintains high measurement precision. The light measurement device includes: light source that irradiates light upon measurement object; branch part that splits transmitted light or reflected light from measurement object; phase-changing unit that changes the phase of one beam of the branched light beams; phase-fixing unit that maintains the phase of the other beam of the branched light beams; adjustment mechanism, which is provided in phase-changing unit or phase-fixing unit, for adjusting the propagation direction of light; multiplexer that causes the light emitted by each of phase-changing unit and phase-fixing unit to interfere with each other; detection unit that detects light that is interfered with by multiplexer; and control unit that controls the adjustment mechanism on the basis of the luminance values of an interference image that is detected by detection unit and adjusts the propagation direction of light in phase-changing unit or phase-fixing unit.
    Type: Application
    Filed: August 7, 2017
    Publication date: July 4, 2019
    Applicants: NEC CORPORATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Takeshi AKAGAWA, Masahiro KUBO, Katsumi ABE, Kimiyasu TAKOH, Ersin ALTINTAS, Yuji OHNO, Tetsuri ARIYAMA, Ichiro ISHIMARU
  • Publication number: 20190175435
    Abstract: A muscular strength assisting apparatus includes a drive means held by a first attachment tool attached to a torso, and a transmission means for transmitting a force output by the drive means to a second attachment tool attached to an upper arm. The transmission means includes an output shaft member coupled to the second attachment tool, and a switching means capable of switching between transmission and interruption of a force from the drive means to the output shaft member. The switching means is disposed on a rear, upper or laterally outer side of the output shaft member.
    Type: Application
    Filed: June 23, 2017
    Publication date: June 13, 2019
    Applicant: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Daisuke SASAKI, Isao KIKUTANI, Kazuya YOKOYAMA
  • Publication number: 20190135890
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Application
    Filed: January 16, 2019
    Publication date: May 9, 2019
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, OCHSNER CLINIC FOUNDATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Robert C. Gensure, Joshua Sakon, Osamu Matsushita, Tulasi Ponnapakkam
  • Patent number: 10202434
    Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: February 12, 2019
    Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, OCHSNER CLINIC FOUNDATION, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventors: Robert C. Gensure, Joshua Sakon, Osamu Matsushita, Tulasi Ponnapakkam
  • Patent number: 10190927
    Abstract: To provide a tactile sensor that allows a contact to be displaced largely and can detect fine ruggedness, flexibility, and other features of a surface of a measuring object. A sensor part S includes a frame 10 that includes a side part of a substrate B, a contact 20 that is disposed in parallel to the substrate B so that a tip of the contact 20 projects from a side face of the substrate B, a suspension 30 that supports the contact 20 to the frame 10, and displacement detectors 41 and 42 each of which detects displacement of the contact 20. The side face of the substrate B functions as a sensing surface. The contact 20 coming in contact with a measuring object O is displaced on a level parallel to the substrate B. Since the sensor part S can be configured widely in a planar manner along the substrate B, the structure has higher flexibility of design.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: January 29, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
    Inventor: Hidekuni Takao